6-Day Italy Self-Drive Road Trip With Itinerary from Ancona traveling south to L'aquila, Rome, and Siena

Dive into day 2 of your remarkable road trip in Italy. Today you will explore Ancona, San Vittore, and Loreto, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in L'aquila. You’ll stay here for 1 night.

Immerse yourself in Ancona’s rich culture with today's sightseeing itinerary. Start your journey at Parco Belvedere Posatora. This eye-catching park is sure to ignite your curiosity. Next, dive into the eye-catching features of Frasassi Caves, a must-visit cave system in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Sanctuary Of The Holy House Of Loreto, a captivating church.

When you’re done exploring for the day, you’ll drive to your hotel in L'aquila. Check in and spend some time relaxing before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in L'aquila. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Experience a harmony of flavors at FØRMA contemporary restaurant in L'aquila by securing a reservation in advance. Known for its Bib Gourmand status, FØRMA contemporary restaurant offers a delightful variety of dishes highlighting its delicious contemporary and creative menu. If you're looking to mix things up, DECA offers an enticing alternative with its varied menu.

After savoring a delicious meal, step into the vibrant nightlife at Art Cafè L'aquila, where the evening is just getting started.

Savor another day of unforgettable experiences in Italy!

On day 3 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Vatican City. When you’re not sightseeing, take time to relax at your selected hotel in Rome, where you’ll be staying for 1 night.

Begin your sightseeing with Vatican Museums. This wondrous art museum is one of the top attractions in the city. Proceed to Saint Peter's Square, another must-visit attraction that enhances the city’s allure.

As you wander through the inviting streets of L'aquila, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Sistine Chapel. This astonishing chapel is a traveler-favorite. Not far away, you’ll find St. Peter's Basilica, another key site on your sightseeing itinerary.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Have a memorable dining experience in Rome by booking a table at La Pergola, renowned as a 3-star Michelin restaurant presenting an exceptional mediterranean and contemporary menu. For a different culinary experience in Rome, Il Pagliaccio shines as one of the top destinations, known for its delicious creative and innovative cuisine. This 2-star Michelin-awardee earns consistently high praises from previous guests, making it a must-visit addition to your holiday experience. If you're looking for an alternative, Enoteca La Torre is known as a top local spot for its delicious mediterranean and creative cuisine in Rome. This 2-star Michelin awardee is a highly recommended choice for an unforgettable meal.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at La Botticella Of Poggi Giovanni, a well-loved spot among locals and tourists. Or, head to Almalu Trastevere. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Bar Viminale Di Pepi Maurilio, another top-rated place in the area.

Take some time to reflect on your day and savor another beautiful night in Italy.

Experience an unparalleled adventure on day 4 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Rome. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Siena. You will spend 1 night here for some well-deserved relaxation.

Prepare for a day full of fun adventures, scenic views, and photo-friendly spots. When you’re ready, kick off your sightseeing adventure at Roman Forum. This globally renowned archeological site is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Colosseum, one of the city’s most promising highlights.

Next, check out Piazza Navona, one of the most globally renowned places to see in Rome. This public square is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Pantheon. Wander around and soak in the respected atmosphere this monument offers. Finally, take the path to the globally renowned Trevi Fountain, the last of our attraction recommendations for today.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Siena. Siena offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Siena's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a lovely meal at Enoteca I Terzi, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Ristorante Tar-Tufo is another top choice with a popular menu. You could also check for a table at Antica Trattoria Papei. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Siena tonight.

Explore the vibrant nightlife at Meet Life Cafè after your meal, a hub for lively evenings and memorable moments. Or, head to Maudit Pub for a great selection of flavorful drinks and a charming setting. Furthermore, Bar Impero Siena is perfect for those looking to extend their night with a touch of local flavor.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Embark on another extraordinary experience on day 5 of your road trip in Italy. Today, you will make 2 stops and experience some of the highlights of Siena and Santa Maria degli Angeli. At the end of the day, you will enjoy the comforts of a top-rated hotel in Ancona, which will be your home away from home for 1 night.

Get ready for a day filled with family-friendly attractions, romantic experiences, and breathtaking views in the charming city of Siena. Your adventure starts at Piazza Del Campo, a spectacular local hot spot. Another notable attraction to explore is Siena Cathedral. This locally renowned church is known for its UNESCO world heritage-designated appeal.

After soaking in the highlights of these sights, take some time to wander Siena's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Fortezza Medicea (siena). This awe-inspiring monument offers a fascinating experience that many visitors find memorable. Basilica Of San Francesco D'assisi is also worth visiting.

When you’re done exploring for the day, you’ll drive to your hotel in Ancona. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Ancona's best restaurants.

Start your culinary exploration in Ancona by securing a reservation at Sot'Ajarchi. This renowned restaurant holds a Bib Gourmand award and offers an exceptional menu of seafood and from the marches cuisine. Immerse yourself in the culinary delights of Bontà delle Marche, a popular restaurant in Ancona. With a menu designed to delight, it ensures a dining experience that transcends the ordinary.

Following your dinner, dive into the local bar culture at Alla Tazza D'oro. Enjoy this evening's relaxed ambiance with delightful drinks.

Say good night to Ancona and look forward to another great day of your road trip in Italy!