5-Day Greece road trip from Thessaloniki to Trikala and Larissa

Your road trip adventure in Greece begins as soon as you reach the incredible city of Thessaloniki. You’ll stay in Thessaloniki for 2 nights, experiencing all the best things to do and see in the city.

Thessaloniki has many popular destinations you can explore. You could visit attractions like the incredible Aristotelous Square. This attraction is a square and has an average rating of 4.7 out of 5 stars by 42,179 visitors.

When you're done sightseeing for the day, you'll check in at one of the best hotels or places to stay in the city. Your stay promises to be a delightful continuation of your exploration, providing comfort and tranquility to recharge for the adventures that lie ahead.

When you’re ready for dinner, we recommend you try one of the best restaurants in the city of Thessaloniki, Kanoula. The restaurant is rated an average of 4.8 out of 5 stars by 2,335 customers.

Another of the best restaurants in the city of Thessaloniki is rOOTS. This restaurant is rated an average of 4.7 out of 5 stars by 2,104 customers.

Locals recommend Opsopoion Maganeiai as one of the best restaurants in the city of Thessaloniki. This restaurant has an average rating of 4.7 out of 5 stars by 1,640 customers.

Thessaloniki also has several great bars that will fit all travel budgets. One of the best bars in the city of Thessaloniki is Pulp. This bar has an average rating of 4.7 out of 5 stars by 1,573 customers.

Another of the best bars in the city of Thessaloniki is Makedonia Palace Hotel. This bar is rated an average of 4.7 out of 5 stars by 10,530 customers.

Locals also enjoy Kitchen Bar. This bar has an average rating of 4.3 out of 5 stars by 9,067 customers.

Enjoy toasting the start of your 5-day vacation in Greece!

Day 2 of your road trip through Greece gives you the opportunity to experience two places in one day. You'll start your day with some exploring in the city of Thessaloniki and end it at a top-rated hotel in the city of Trikala. You will stay in Trikala for 1 night. Have a hearty breakfast and get excited for a wonderful day ahead!

One of the best places to visit today in Thessaloniki is the amazing Kapani. This attraction is a market that is rated an average of 4.4 out of 5 stars by 11,510 visitors.

You could also stop at the incredible square, Agias Sofias Square. With an average rating of 4.6 out of 5 stars by 10,128 visitors, this attraction is one of the top sights in the area.

Another unforgettable travel destination in the Thessaloniki is the outstanding The Umbrellas Sculpture by Zogolopoulos. This popular must-see tourist destination and travel destination has an average rating of 4.7 out of 5 stars by 13,531 visitors.

The spectacular White Tower of Thessaloniki is another popular attraction you can visit today. This fascinating fortified tower and attraction has an average rating of 4.7 out of 5 stars from 50,663 visitors. In addition, approximately 290,192 travelers visit this popular site annually.

If you’re keen to explore even more, then consider a visit to the fantastic Heptapyrgion of Thessaloniki. This attraction is a popular top-tier point of interest that has an average rating of 4.6 out of 5 stars from 5,550 visitors.

You can make the most of your new day in Thessaloniki by joining activities and tours that let you discover what else the city has in store for you. There are many top-rated experiences you can include in your travel plan to add flavor to your road trip in Greece. Browse all of your options and reserve your slot before it's too late.

At the end of the day, you will drive to the city of Trikala, where you will access the best hotels and places to stay.

After a long day of driving and exploring, we recommend you try Ouzo Vasilis, one of the best restaurants in the city of Trikala. This restaurant has an average rating of 4.7 out of 5 stars by 972 customers.

Locals also recommend To Chani as one of the best restaurants in the city of Trikala. To Chani is rated an average of 4.6 out of 5 stars by 2,894 customers.

Another of the best restaurants in the city of Trikala is Palia Istoria. This restaurant has been rated an average of 4.5 out of 5 stars by 1,654 customers.

After dinner, visit Krypti Mpar, which is considered one of the best bars in the city of Trikala. This bar is rated an average of 4.7 out of 5 stars by 620 customers.

You can also enjoy drinks at a popular bar like Bonjour Cafe Trikala. This bar has an average rating of 4.3 out of 5 stars by 1,081 customers.

Alternatively, Ivy is one of the best bars that locals recommend in the city of Trikala. This bar is rated an average of 4.6 out of 5 stars by 766 customers.

Raise your glass in celebration of your incredible road trip adventure through Greece!

Day 3 of your road trip through Greece is your chance to discover two places in one day, the city of Trikala and the city of Kastraki. Get ready to experience some of the most famous attractions in the area!

One of the best places to visit in the city of Trikala is the amazing Matsopoulos Park. This attraction is a park and is rated an average of 4.7 out of 5 stars by 8,871 visitors.

Joining a top-rated tour in Trikala is another excellent way to spend your new day in Greece. The best tours in this travel destination will take you on an exploration to some of Greece’s most well-known attractions and best-kept secrets.

With this tour, you’ll set out on a journey to Greece’s most interesting sights. As you go along this remarkable tour, you’ll also have the unique opportunity to catch a glimpse of Greece’s scenic spots.

You could then travel to the amazing Meteora in the city of Kastraki for some sightseeing. This popular attraction is a monastery and has been rated an average of 4.9 out of 5 stars by 35,413 visitors.

Another unforgettable travel destination in the village of Kastraki is the outstanding The Great Meteoron Holy Monastery of the Transfiguration of the Saviour. Rated 4.8 out of 5 stars by 8,462 visitors, this place of worship deserves a spot on travelers' bucket lists.

You’ll also have your choice of the best hotels and places to stay in the city of Larissa.

After a long day of driving and exploring, we recommend you try Las Ramblas Coffeebar, one of the best restaurants in the city of Larissa. This restaurant has an average rating of 4.5 out of 5 stars by 2,338 customers.

Locals also recommend Mpakalógatos as one of the best restaurants in the city of Larissa. Mpakalógatos is rated an average of 4.4 out of 5 stars by 1,836 customers.

Another of the best restaurants in the city of Larissa is Akamatra - Akamatra. This restaurant has been rated an average of 4.6 out of 5 stars by 1,383 customers.

After dinner, visit Nonna Rossa, which is considered one of the best bars in the city of Larissa. This bar is rated an average of 4.5 out of 5 stars by 2,797 customers.

You can also enjoy drinks at a popular bar like Gossip Downtown. This bar has an average rating of 4.6 out of 5 stars by 1,557 customers.

Alternatively, Klímax is one of the best bars that locals recommend in the city of Larissa. This bar is rated an average of 4.3 out of 5 stars by 1,734 customers.

Raise your glass in celebration of your incredible road trip adventure through Greece!

Rise and shine on day 4 of your road trip in Greece. Today, you'll wake up in Larissa and embark on a scenic drive to Thessaloniki, where you'll stay at one of the best hotels for 1 night. Seize the opportunity to explore spectacular attractions in Larissa and Vergina before you reach your end destination for the day.

It’s hard not to feel excited about visiting attractions in a destination as lovely as Larissa. When you’re eager to explore the city and nearby areas, we recommend visiting some local favorites, such as the wonderful Katerini Municipal Park. This attraction is a park that has an average rating of 4.6 out of 5 stars from 6,501 visitors.

Wave goodbye to Katerini and continue your journey by car. If you want to break up today’s drive into two, take the opportunity to stop and discover what the city of Vergina has to offer.

One of the most popular attractions you can visit is the remarkable Museum of the Royal Tombs at Aigai (Aegae). This attraction is a museum that has an average rating of 4.8 out of 5 stars from 8,329 visitors.

When you're done with your sightseeing in Vergina, it's time to continue your drive to the city of Thessaloniki. When you arrive in Thessaloniki you’ll check in at one of the best hotels in the area.

We recommend you end the day with a dinner at a popular restaurant near your accommodation, like Giok Balik. This restaurant offers various delicious and comforting meals and has an average rating of 4.4 out of 5 stars from 4,336 customers.

Locals also recommend Loupino Restaurant, another of the best restaurants in Thessaloniki. Loupino Restaurant is rated an average of 4.4 out of 5 stars by 3,657 customers.

If you feel like having something else, check out the menu at Sebriko. This restaurant has been rated an average of 4.6 out of 5 stars by 2,978 customers and is a great place to enjoy a lovely meal.

After dinner, visit Dentro sto Bar to enjoy a couple of drinks and relax. This bar is one of the best in Thessaloniki, with an average rating of 4.5 out of 5 stars by 4,446 customers.

You can also enjoy drinks at a popular bar like Wall by Wall. This bar is a great spot to meet new friends and celebrate your vacation. Wall by Wall has an average rating of 4.5 out of 5 stars by 4,128 customers.

SKYLINE - OTE Tower is another bar locals often recommend. This bar offers a great variety of snacks and drinks and is rated an average of 4.6 out of 5 stars by 3,534 customers.

End your day by raising your glass in celebration of your incredible road trip adventure in Greece, and look forward to more great days to come!

Day 5 of your road trip in Greece is your departure day. This is your chance to catch one last glimpse of Thessaloniki before saying goodbye to this wonderful destination. When you have time to explore the area before you make your way home, we recommend visiting some of the following attractions.

Arch of Galerius and Rotunda is an extraordinary attraction you could visit to enjoy your last day in Thessaloniki. This tetrapylon and popular site of interest has an average rating of 4.6 out of 5 stars by 11,979 visitors.

Take a stroll along the main shopping streets of Thessaloniki and find some souvenirs to remind you of your road trip in Greece.

You could then enjoy your last meal in the city of Thessaloniki at Charoupi before you travel home. This popular restaurant is rated an average of 4.6 out of 5 stars by 2,912 customers.

Alternatively, we also recommend The Rouga for your last chance at a meal in the city of Thessaloniki. The The Rouga restaurant has an average rating of 4.6 out of 5 stars by 2,900 customers.

If you'd prefer a popular restaurant that locals enjoy, try The Greek. This restaurant has an average rating of 4.5 out of 5 stars by 3,117 customers.

You’ll then say farewell to Thessaloniki. We wish you a pleasant journey home, with many wonderful memories of your unforgettable vacation in Greece!