10-Day the Czech Republic Self-Drive Road Trip With Itinerary from Prague to Ceske Budejovice, Plzeň, and Ústí Nad Labem and surrounding area

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Photo of famous Charles Bridge over the Vltava river in Prague, Czech Republic.
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Explore the best of the Czech Republic on a remarkable 10-day road trip! Combine exploration with relaxation on a self-drive tour featuring Prague, Průhonice, Český Krumlov, Ceske Budejovice, Hluboká nad Vltavou, Blatná, Plzeň, Loket, Carlsbad, Ústí Nad Labem, Děčín, Mezná, Růžová, and Labská Stráň.

This perfectly planned road trip itinerary takes you through some of the best places to see in the Czech Republic. You will spend 5 nights in Prague, 1 night in Ceske Budejovice, 2 nights in Plzeň, and 1 night in Ústí Nad Labem. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Prague, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Prague Castle and Charles Bridge are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Prague, Průhonice, Český Krumlov, Ceske Budejovice, Hluboká nad Vltavou, Blatná, Plzeň, Loket, Carlsbad, Ústí Nad Labem, Děčín, Mezná, Růžová, and Labská Stráň, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Driver’s age is 30 - 65
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Day1

Day 1

  • Prague - Arrival day
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  • Charles Bridge
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Welcome to Prague, the perfect starting point for your road trip in the Czech Republic! Pick up your rental car and let the adventure begin. You will spend 4 nights discovering what to see in Prague before embarking on the next leg of your journey.

Prague is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Charles Bridge. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Prague. Check-in typically starts around 2 to 4 PM at hotels in the Czech Republic. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Savor the flavors at U Tellerů, a top pick for dinner tonight. Alternatively, Restaurace U Bansethů beckons with its unique menu offerings. Also, consider Eska Restaurant and Bakery. With its consistent customer satisfaction, it’s an excellent option for dining in Prague tonight.

After savoring a delicious meal, step into the vibrant nightlife at Anonymous Shrink's Office, where the evening is just getting started. In the same way, Bar No. 7 - Prague offers a unique charm perfect for experiencing the local bar scene in Prague. Kontakt Bar is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise a toast to the start of your 10-day road trip in the Czech Republic!

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Day2

Day 2

  • Prague
  • More

Drive 5 km, 49 min

  • Old Town Square
  • Prague Astronomical Clock
  • Lennon Wall
  • St. Vitus Cathedral
  • Prague Castle
  • More

On day 2 of your road trip, you will have an entire day to discover what to see in Prague. You’ll stay in Prague for 3 nights.

Check out the iconic public square, Old Town Square. Afterward, continue to Prague Astronomical Clock, a historical landmark every traveler should visit. As you explore Prague’s charming streets, take in the lively atmosphere and get to know the character of the city.

Next, make your way to Lennon Wall. This popular street art is an essential stop. Following that, head to St. Vitus Cathedral, another must-visit site that will enhance your experience. Don’t forget to stop by Prague Castle, an iconic castle in the city.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Prague's best restaurants.

Treat yourself to a delightful dinner at Brasileiro Restaurant, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Restaurant Meat Beer? It's another excellent option with a diverse menu. Consider reserving a table at Restaurace Století as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Prague.

Keep the evening going at Bowla Bar, a great choice for enjoying the after-dinner hours with a drink. You could also go to The Saints, which offers a similarly pleasant setting and great drinks. Another option is Beergeek Bar, which provides an inviting environment for unwinding after a busy day out.

Raise your glass and celebrate another amazing day of your road trip in the Czech Republic!

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Day3

Day 3

  • Prague
  • More

Drive 34 km, 1 hour 35 min

  • Vyšehrad
  • Letná Park
  • Královská obora Stromovka
  • Prague Zoo
  • Nature Park Draháň-Troja
  • More

Day 3 offers an itinerary packed with the best things to see in Prague. You’ll stay in Prague for 2 nights more, offering you enough time to explore at a relaxed pace.

Vyšehrad brings Prague's character to life. This enchanting castle is a highlight of any visit in the city. Then, enjoy Letná Park, another serene attraction that never fails to captivate visitors. Next, head over to Stromovka, one of the city’s most well-known attractions, known for its romantic features.

If you’re looking for more, spend time soaking in the atmosphere of Prague Zoo. This stunning zoo is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Nature Park Draháň-troja, an interesting nature reserve, and take a stroll around the area.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

Prague is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Prague.

Treat yourself to a wonderful meal at BeBop Bar, a top-rated dining spot in Prague. If you're in the mood for something new, try Café restaurant Palanda, another premier location with a delectable menu. You might also want to book a table at Restaurace Tiskárna. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Prague.

Continue your evening by exploring the vibrant nightlife scene at Uhříněveský Bar, a prime destination for a thrilling night out. Also, don’t forget to check out Boothill Bar, a bar that offers unique local touches. Likewise, Manesova Bar And Books provides an excellent alternative for a fun evening.

Relax and look forward to more memorable moments to come!

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Day4

Day 4

  • Prague
  • More

Drive 10 km, 1 hour 6 min

  • Dancing House
  • National Theatre
  • Franz Kafka - Rotating Head
  • Powder Tower
  • National Museum in Prague
  • More

Day 4 of your road trip will take you to the best attractions Prague has to offer. Cherish the 1 night you have left in the city and use the provided itinerary to discover what to see in Prague.

Catch Dancing House before the crowds roll in. This standout art installation is sure to ignite your curiosity. Next, dive into the enchanting features of National Theatre, a must-visit performing arts theater in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Franz Kafka - Rotating Head By David Cerny, a notable art installation. For a change of scene, check out Powder Tower, known for its culturally significant features. We also recommend visiting Národní Muzeum (national Museum, Prague). This museum is a must for anyone looking to experience the city to the fullest.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at OSSEGG Praha - Pivovar & Restaurace, an excellent option for tonight's dining. Looking for something different? U Fleků offers a tantalizing alternative with its diverse menu. And don’t miss Havelská Koruna. Known for great service, it’s a fantastic choice for tonight in Prague.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Bar Bohužel, a well-loved spot among locals and tourists. Or, head to Hemingway Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Bar Tečka, another top-rated place in the area.

As the sun sets, rest up and recharge for the next leg of your road trip in the Czech Republic.

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Day5

Day 5

  • Prague
  • České Budějovice
  • More

Drive 207 km, 3 hours 7 min

  • Park Průhonice
  • The Castle Garden
  • State Castle and Chateau Český Krumlov
  • More

Dive into day 5 of your remarkable road trip in the Czech Republic. Today you'll explore 2 destinations, including Průhonice and Český Krumlov. At the end of the day, you’ll unwind at one of the finest accommodations in Ceske Budejovice, where you'll spend 1 night.

Whatever your travel style is, Park Průhonice is an essential stop in Prague. This underrated botanical garden provides an insightful glimpse into the village's identity. Next, discover The Castle Garden, an UNESCO world heritage-designated castle, promising a delightful encounter.

Continue your sightseeing with a visit to Český Krumlov Castle, a notable castle.

When you’re done exploring for the day, you’ll drive to your hotel in Ceske Budejovice. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Ceske Budejovice's best restaurants.

Make sure to reserve a table at Potrefená husa IGY, České Budějovice, an iconic dining spot in Ceske Budejovice. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Paluba, a popular restaurant in Ceske Budejovice. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Alchymista, a hidden gem nestled in Ceske Budejovice. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your dinner by heading to The Dark, ideal for a leisurely evening with a drink in hand. Cafe Hostel is another bar that offers an enjoyable setting. Similarly, Singer Pub is also a popular place to go on a night out, perfect for relaxing and socializing.

Take some time to reflect on your day and savor another beautiful night in the Czech Republic.

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Day6

Day 6

  • České Budějovice
  • Plzeň-City District
  • More

Drive 147 km, 2 hours 25 min

  • Samson fountain
  • Black Tower
  • The State Chateau of Hluboká
  • Ohrada Zoo
  • Castle Blatná
  • More

On day 6 of your road trip in the Czech Republic, your travel plans include 3 stops at the most scenic, wondrous, and interesting places in the region. Ceske Budejovice, Hluboká nad Vltavou, and Blatná are on today's agenda. In the evening, you’ll end up in Plzeň, where you will stay for 2 nights.

Look forward to a unique sightseeing adventure at the curiosity-inducing Samson Fountain and allow yourself time to explore. Just a short distance away you'll find your next stop, Black Tower, a picture-perfect monument that draws visitors from far and near.

Continue your journey to The State Chateau Of Hluboká, one of the city’s most notable spots that you shouldn’t miss. Another great site to visit is the notable Ohrada Zoo. When you're finished at the zoo, Castle Blatná awaits your visit. This castle is a stunning highlight on today's itinerary.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Plzeň. Plzeň offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Plzeň. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Dine in style at Raven Pub City, a top recommendation for dinner tonight. Or, for a change of pace, Restaurace & Hotel U Salzmannů boasts a menu that's sure to impress. Also, be sure to check out Pláž OSTENDE BOLEVÁK. Known as a local hotspot, it’s a great choice for tonight in Plzeň.

Keep the excitement of the evening going by visiting a bar or two. Francis - Beer Café is an excellent place to start. You could also check out My Friends Bar, offering a different kind of charm. A last recommendation for the day is Beer Bar Pioneer. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Raise your glass and celebrate another amazing day of your road trip in the Czech Republic!

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Day7

Day 7

  • Plzeň-City District
  • More

Drive 8 km, 44 min

  • Plzeň Zoo
  • Cathedral of St. Bartholomew
  • Náměstí Republiky, Plzeň
  • Pilsner Urquell Brewery
  • More

Day 7 of your road trip across the Czech Republic promises a magnificent time exploring what to see in Plzeň. You have 1 night left in Plzeň. Take the opportunity to experience more of the best attractions and activities in the city.

Make time for Dinopark Plzeň, a locally renowned zoo that is worthwhile a visit in the city. Nearby, you’ll find Cathedral Of St. Bartholomew, enchanting visitors with its breathtaking appeal. Continue your exploration at Náměstí Republiky, Plzeň. This public square is one of the city’s most underrated spots.

Enjoy the freedom of exploring Plzeň at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Pilsner Urquell Brewery.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Plzeň. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a delicious meal at Mely Restaurant, a top-rated dining destination in Plzeň. If you're in the mood to try something new, consider Parkan, another top spot with a mouthwatering menu. You might also want to secure a reservation at Restaurace U Lízalky. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Plzeň this evening.

Let the evening flow smoothly from dinner to drinks at Cafe La Rose, Ltd. , a top-rated bar in the area. For other recommendations, Forest Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Vinyl Coffee & Pub offers a memorable night with diverse drink options and excellent service.

Get a good night's sleep and look forward to another great day on the road in the Czech Republic!

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Day8

Day 8

  • Plzeň-City District
  • Ústí nad Labem
  • More

Drive 217 km, 4 hours 9 min

  • Loket Castle
  • Vřídelní kolonáda
  • Mill Colonnade
  • Diana Observation Tower
  • More

Your itinerary for day 8 of your road trip in the Czech Republic includes 2 stops and features some of the highlights of Loket and Carlsbad. At the end of the day, enjoy the comforts of a top-rated hotel in Ústí Nad Labem, where you'll spend 1 night.

Loket Castle brings Plzeň's character to life. This awe-inspiring castle is a highlight of any visit in the town. Then, enjoy Vřídelní Kolonáda, another history-steeped attraction that never fails to captivate visitors. Next, head over to Mill Colonnade, one of the town’s most interesting attractions, known for its majestic features.

If you’re looking for more, spend time soaking in the atmosphere of Rozhledna Diana. This visually striking observation deck is frequented by locals and tourists alike. To complete your memorable day, make sure to take a stroll around the area.

At the end of the day, you will drive to Ústí Nad Labem, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Ústí Nad Labem. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a lovely meal at Restaurant Větruše, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Hotel a Restaurant Větruše is another top choice with a popular menu. You could also check for a table at BLACKSHEEP BAR. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Ústí Nad Labem tonight.

Explore the vibrant nightlife at Hp Bar after your meal, a hub for lively evenings and memorable moments. Or, head to Ústecká Pivotéka for a great selection of flavorful drinks and a charming setting. Furthermore, Pubs Bar Hamburg is perfect for those looking to extend their night with a touch of local flavor.

Head back to your accommodation in Ústí Nad Labem and get some rest to prepare for another magical day of your road trip in the Czech Republic.

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Day9

Day 9

  • Ústí nad Labem
  • Prague
  • More

Drive 199 km, 3 hours 16 min

  • Děčín Zoo
  • Kamenice Gorge
  • Bohemian Switzerland National Park
  • Mýdlárna Rubens
  • Labské pískovce Protected Landscape Area
  • More

On day 9 of your exciting self-drive vacation in the Czech Republic, you’ll soak in the magnificence of 4 destinations, including Děčín, Mezná, Růžová, and Labská Stráň. When you’re not sightseeing, take time to relax at your chosen hotel in Prague, where you’ll be staying for 1 night.

Enjoy all that Děčín Zoo has to offer. This is a frequently visited zoo you should not miss. Another must-see is Kamenice Gorge, an intriguing canyon in Ústí Nad Labem.

When you’re ready for the next sight, head to České Švýcarsko National Park. From there, take a leisurely stroll to Mýdlárna Rubens, another of the town’s curiosity-inducing attractions. We recommend continuing your self-guided tour at Protected Landscape Area Elbe Sandstone Mountains, a romantic place of interest in the town.

When you’re done exploring for the day, you’ll drive to your hotel in Prague. Check in and relax before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at MAURIZIO restaurant & café, an excellent option for tonight's dining. Looking for something different? Gate Restaurant offers a tantalizing alternative with its diverse menu. And don’t miss U Houmra. Known for great service, it’s a fantastic choice for tonight in Prague.

Following your dinner, dive into the local bar culture at Crazy Daisy. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Puerto Rico Cafe & Cocktail Bar, the perfect place for those looking to experience the best of the nightlife. Similarly, Anonymous Bar provides excellent drinks and a great atmosphere, ensuring a memorable night out.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in the Czech Republic.

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Day10

Day 10

  • Prague - Departure day
  • More
  • Clementinum
  • More

Day 10 of your road trip in the Czech Republic is your departure day. This is your chance to catch a last glimpse of Prague before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Clementinum, an eye-catching library before you head out.

For a shopping spree in Prague, we recommend the lively Na Příkopě Street. Here, you'll find a range of shops you can browse for some souvenir shopping.

Before you conclude your road trip in the Czech Republic, drop by another restaurant for a last chance at a memorable dining experience in Prague.

You’ll then say farewell to Prague. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
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Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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