10-Day the Czech Republic Self-Drive Road Trip With Itinerary from Prague to Ceske Budejovice, Plzeň, and Ústí Nad Labem and surrounding area

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Photo of famous Charles Bridge over the Vltava river in Prague, Czech Republic.
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Description

Explore the best of the Czech Republic on a remarkable 10-day road trip! Combine exploration with relaxation on a self-drive tour featuring Prague, Průhonice, Český Krumlov, Ceske Budejovice, Hluboká nad Vltavou, Blatná, Plzeň, Loket, Carlsbad, Ústí Nad Labem, Děčín, Mezná, Růžová, and Labská Stráň.

This perfectly planned road trip itinerary takes you through some of the best places to see in the Czech Republic. You will spend 5 nights in Prague, 1 night in Ceske Budejovice, 2 nights in Plzeň, and 1 night in Ústí Nad Labem. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Prague, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Prague Castle and Charles Bridge are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Prague, Průhonice, Český Krumlov, Ceske Budejovice, Hluboká nad Vltavou, Blatná, Plzeň, Loket, Carlsbad, Ústí Nad Labem, Děčín, Mezná, Růžová, and Labská Stráň, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
Drop-off: 10:00

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Day 1

Day 1

  • Prague - Arrival day
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  • Charles Bridge
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Your road trip adventure in the Czech Republic begins as soon as you reach Prague and pick up your car. You’ll stay here for 4 nights and explore what to see in Prague, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Prague is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Prague. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in the Czech Republic. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Raise a toast to the start of your 10-day road trip in the Czech Republic!

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Day 2

Day 2

  • Prague
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Drive 5 km, 49 min

  • Old Town Square
  • Prague Astronomical Clock
  • Lennon Wall
  • St. Vitus Cathedral
  • Prague Castle
  • More

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Prague. Enjoy a relaxing evening as you savor delicious local cuisine.

As the sun sets, rest up and recharge for the next leg of your road trip in the Czech Republic.

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Day 3

Day 3

  • Prague
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Drive 34 km, 1 hour 35 min

  • Vyšehrad
  • Letná Park
  • Královská obora Stromovka
  • Prague Zoo
  • Nature Park Draháň-Troja
  • More

You have 2 nights left in Prague. Take the opportunity to experience more of the best attractions and activities in the city.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Prague's best restaurants.

Savor another day of unforgettable experiences in the Czech Republic!

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Day 4

Day 4

  • Prague
  • More

Drive 10 km, 1 hour 6 min

  • Dancing House
  • National Theatre
  • Franz Kafka - Rotating Head
  • Powder Tower
  • National Museum in Prague
  • More

Day 4 offers an itinerary packed with the best things to see in Prague. You’ll stay in Prague for 1 night more, offering you enough time to explore at a relaxed pace.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

Bring home unique finds from Prague's bustling shopping hub, Na Příkopě Street. Enjoy a leisurely exploration of unique stores where locals shop. Don’t forget to browse souvenirs and local specialties that make perfect gifts for your loved ones. Beyond shopping, Na Příkopě Street offers plenty of options, including primary services, unique landmarks, and community events.

Indulge in a memorable dining experience at one of Prague's most popular restaurants, and connect with friendly locals for a true cultural experience.

Relax and look forward to more memorable moments to come!

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Day 5

Day 5

  • Prague
  • České Budějovice
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Drive 207 km, 3 hours 7 min

  • Park Průhonice
  • The Castle Garden
  • State Castle and Chateau Český Krumlov
  • More

Dive into day 5 of your remarkable road trip in the Czech Republic. Today you'll explore 2 destinations, including Průhonice and Český Krumlov. At the end of the day, you’ll unwind at one of the finest accommodations in Ceske Budejovice, where you'll spend 1 night.

Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Prague.

When you’re done exploring for the day, you’ll drive to your hotel in Ceske Budejovice. Check in and relax before you head out to tour the city.

Ceske Budejovice is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Ceske Budejovice.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in the Czech Republic.

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Day 6

Day 6

  • České Budějovice
  • Plzeň-City District
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Drive 147 km, 2 hours 25 min

  • Samson fountain
  • Black Tower
  • The State Chateau of Hluboká
  • Ohrada Zoo
  • Castle Blatná
  • More

Your itinerary for day 6 of your road trip in the Czech Republic includes 3 stops and features some of the highlights of Ceske Budejovice, Hluboká nad Vltavou, and Blatná. At the end of the day, enjoy the comforts of a top-rated hotel in Plzeň, where you'll spend 2 nights.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Plzeň. Plzeň offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Plzeň, it's often a good idea to reserve a table in advance.

Raise your glass and celebrate another amazing day of your road trip in the Czech Republic!

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Day 7

Day 7

  • Plzeň-City District
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Drive 8 km, 44 min

  • Plzeň Zoo
  • Cathedral of St. Bartholomew
  • Náměstí Republiky, Plzeň
  • Pilsner Urquell Brewery
  • More

You’ll stay in Plzeň for 1 night.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Plzeň. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Head back to your accommodation in Plzeň and get some rest to prepare for another magical day of your road trip in the Czech Republic.

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Day 8

Day 8

  • Plzeň-City District
  • Ústí nad Labem
  • More

Drive 217 km, 4 hours 9 min

  • Loket Castle
  • Vřídelní kolonáda
  • Mill Colonnade
  • Diana Observation Tower
  • More

Experience an unparalleled adventure on day 8 of your road trip in the Czech Republic. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Loket and Carlsbad. At the end of the day, you will retreat to the hotel of your choice in Ústí Nad Labem, where will spend 1 night.

At the end of the day, you will drive to Ústí Nad Labem, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Ústí Nad Labem. Enjoy a relaxing evening as you savor delicious local cuisine.

Say good night to Ústí Nad Labem and look forward to another great day of your road trip in the Czech Republic!

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Day 9

Day 9

  • Ústí nad Labem
  • Prague
  • More

Drive 199 km, 3 hours 16 min

  • Děčín Zoo
  • Kamenice Gorge
  • Bohemian Switzerland National Park
  • Mýdlárna Rubens
  • Labské pískovce Protected Landscape Area
  • More

On day 9 of your exciting self-drive vacation in the Czech Republic, you’ll soak in the magnificence of 4 destinations, including Děčín, Mezná, Růžová, and Labská Stráň. When you’re not sightseeing, take time to relax at your chosen hotel in Prague, where you’ll be staying for 1 night.

When you’re done exploring for the day, you’ll drive to your hotel in Prague. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Prague. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Take some time to reflect on your day and savor another beautiful night in the Czech Republic.

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Day 10

Day 10

  • Prague - Departure day
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  • Clementinum
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Day 10 of your road trip in the Czech Republic is your departure day. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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How it works

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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