10-Day the Czech Republic Self-Drive Road Trip With Itinerary from Prague to Ceske Budejovice, Plzeň, and Ústí Nad Labem and surrounding area

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Explore the best of the Czech Republic on a 10-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Prague, Průhonice, Český Krumlov, Ceske Budejovice, Hluboká nad Vltavou, Blatná, Plzeň, Loket, Carlsbad, Ústí Nad Labem, Děčín, Mezná, Růžová, and Labská Stráň. This road trip itinerary in the Czech Republic seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in the Czech Republic takes you through some of the best places to see in the country. You will spend 5 nights in Prague, 1 night in Ceske Budejovice, 2 nights in Plzeň, and 1 night in Ústí Nad Labem. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Prague, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Prague Castle and Charles Bridge are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Old Town Square, learn more about the unique St. Vitus Cathedral, and immerse yourself in the vibrant atmosphere of Prague Astronomical Clock.

As you hit the open road and drive through Prague, Průhonice, Český Krumlov, Ceske Budejovice, Hluboká nad Vltavou, Blatná, Plzeň, Loket, Carlsbad, Ústí Nad Labem, Děčín, Mezná, Růžová, and Labská Stráň, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Charles Bridge
Old Town SquarePrague Astronomical ClockLennon WallSt. Vitus CathedralPrague Castle
VyšehradLetná ParkKrálovská obora StromovkaPrague ZooNature Park Draháň-Troja
Dancing HouseNational TheatreFranz Kafka - Rotating HeadPowder TowerNational Museum in Prague
Park PrůhoniceThe Castle GardenState Castle and Chateau Český Krumlov
Samson fountainBlack TowerThe State Chateau of HlubokáOhrada ZooCastle Blatná

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Day 1

Day 1

  • Prague - Arrival day
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  • Charles Bridge
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Welcome to Prague, the perfect starting point for your road trip in the Czech Republic! Pick up your rental car and let the adventure begin. You will spend 4 nights immersing yourself in Prague's charm before embarking on the next leg of your journey.

Prague is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Charles Bridge, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Prague. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in the Czech Republic. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at U Tellerů, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Restaurace U Bansethů? It's another excellent option with a diverse menu. Consider reserving a table at Eska Restaurant and Bakery as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Prague.

Continue your lively evening at Anonymous Shrink's Office, a perfect place for winding down or revving up the night, depending on which mood you’re in. Bar No. 7 - Prague is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Kontakt Bar ensures a night out tailored to your taste.

Raise a toast to the start of your 10-day road trip in the Czech Republic!

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Day 2

Day 2

  • Prague
  • More

Drive 5 km, 49 min

  • Old Town Square
  • Prague Astronomical Clock
  • Lennon Wall
  • St. Vitus Cathedral
  • Prague Castle
  • More

Day 2 of your road trip across the Czech Republic promises a magnificent time exploring Prague. You have 3 nights left in Prague. Take the opportunity to experience more of the best attractions and activities in the city.

Get ready for a day filled with fun adventures, romantic experiences, and breathtaking views in the charming city of Prague. Your adventure starts at Old Town Square, a globally renowned local hot spot. Another notable attraction to explore is Prague Astronomical Clock. This top-rated historical landmark is known for its enchanting appeal.

After soaking in the highlights of these sights, take some time to wander Prague's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Lennon Wall. This culturally significant street art offers a fascinating experience that many visitors find memorable. St. Vitus Cathedral is also worth visiting, along with Prague Castle. These standout landmarks offer unique experiences that add to the day’s enjoyment.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. The Czech Republic is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Indulge in a memorable dining experience at one of Prague's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a lovely meal at Brasileiro Restaurant, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Restaurant Meat Beer is another top choice with a popular menu. You could also check for a table at Restaurace Století. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Prague tonight.

Following your dinner, dive into the local bar culture at Bowla Bar. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to The Saints, the perfect place for those looking to experience the best of the nightlife. Similarly, Beergeek Bar provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Say good night to Prague and look forward to another great day of your road trip in the Czech Republic!

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Day 3

Day 3

  • Prague
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Drive 34 km, 1 hour 35 min

  • Vyšehrad
  • Letná Park
  • Královská obora Stromovka
  • Prague Zoo
  • Nature Park Draháň-Troja
  • More

Day 3 of your road trip will take you to the best attractions Prague has to offer. Cherish the 2 nights you have left in Prague by discovering the best things there are to see and do in the city.

Today's adventure in Prague promises more breathtaking discoveries and enriching experiences! Begin at Vyšehrad. This romantic castle is a highlight of any visit in the city. Then, enjoy Letná Park, another romantic attraction that never fails to captivate visitors. Next, head over to Stromovka, one of the city’s most captivating attractions, known for its stunning features.

If you’re looking for more, spend time soaking in the atmosphere of Prague Zoo. This picture-perfect zoo is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Nature Park Draháň-troja, a locally renowned nature reserve, and take a stroll around the area.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. The Czech Republic is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Prague, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at BeBop Bar, a highly-rated dining destination in Prague. If you're eager to try something different, consider Café restaurant Palanda, another top spot with a tantalizing menu. You might also want to secure a reservation at Restaurace Tiskárna. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Prague this evening.

Keep the evening going at Uhříněveský Bar, a great choice for enjoying the after-dinner hours with a drink. You could also go to Boothill Bar, which offers a similarly pleasant setting and great drinks. Another option is Manesova Bar And Books, which provides an inviting environment for unwinding after a busy day out.

Relax and recharge in preparation for another adventurous day in the Czech Republic!

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Day 4

Day 4

  • Prague
  • More

Drive 10 km, 1 hour 6 min

  • Dancing House
  • National Theatre
  • Franz Kafka - Rotating Head
  • Powder Tower
  • National Museum in Prague
  • More

Day 4 offers a multitude of experiences. You will stay in Prague for 1 night more, offering you enough time to explore at a relaxed pace.

Discover a day packed with fun adventures, romantic experiences, and breathtaking views in Prague. Begin your sightseeing with Dancing House. This impressive art installation is one of the top attractions in the city. Proceed to National Theatre, another must-visit attraction.

As you wander through the inviting streets of Prague, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Franz Kafka - Rotating Head By David Cerny. This locally renowned art installation is a traveler-favorite. Not far away, you’ll find Powder Tower, another key site on your sightseeing itinerary. Národní Muzeum (national Museum, Prague) is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. The Czech Republic is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Prague's best restaurants.

Dine in style at OSSEGG Praha - Pivovar & Restaurace, a top recommendation for dinner tonight. Or, for a change of pace, U Fleků boasts a menu that's sure to impress. Also, be sure to check out Havelská Koruna. Known as a local hotspot, it’s a great choice for tonight in Prague.

Keep the excitement of the evening going by visiting a bar or two. Bar Bohužel is an excellent place to start. You could also check out Hemingway Bar, offering a different kind of charm. A last recommendation for the day is Bar Tečka. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Take some time to reflect on your day and savor another beautiful night in the Czech Republic.

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Day 5

Day 5

  • Prague
  • České Budějovice
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Drive 207 km, 3 hours 7 min

  • Park Průhonice
  • The Castle Garden
  • State Castle and Chateau Český Krumlov
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Embark on another extraordinary experience on day 5 of your road trip in the Czech Republic. Today, you will make 2 stops and experience some of the highlights of Průhonice and Český Krumlov. At the end of the day, you will enjoy the comforts of a top-rated hotel in Ceske Budejovice, which will be your home away from home for 1 night.

Brace yourself for today’s incredible lineup of attractions in Prague, featuring fun adventures, romantic experiences, and natural wonders. Start at Park Průhonice, a worthwhile botanical garden in the village. Then, head to The Castle Garden and soak in the ambiance of this history-steeped castle.

There are many interesting places to see in Prague, and when you are ready for more, go to Český Krumlov Castle. This is one of the village’s most locally renowned visually striking spots of interest.

When you’re done exploring for the day, you’ll drive to your hotel in Ceske Budejovice. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Ceske Budejovice. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely dining experience at Potrefená husa IGY, České Budějovice, a popular restaurant in Ceske Budejovice. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Ceske Budejovice at Paluba, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Alchymista. It’s yet another ideal choice to enhance your time in Ceske Budejovice tonight.

If you’re not ready to end the night just yet, The Dark offers a perfect venue to relax and savor a drink. Similarly, Cafe Hostel is well-suited for those looking to unwind in a social setting. Singer Pub is another excellent spot to enjoy a nightcap after a delightful meal.

Get a good night's sleep and look forward to another great day on the road in the Czech Republic!

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Day 6

Day 6

  • České Budějovice
  • Plzeň-City District
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Drive 147 km, 2 hours 25 min

  • Samson fountain
  • Black Tower
  • The State Chateau of Hluboká
  • Ohrada Zoo
  • Castle Blatná
  • More

Dive into day 6 of your remarkable road trip in the Czech Republic. Today you will explore Ceske Budejovice, Hluboká nad Vltavou, and Blatná, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Plzeň. You’ll stay here for 2 nights.

Bring your curiosity for today’s adventure around Ceske Budejovice. Some of the city’s most loved attractions await! Samson Fountain is the perfect place to start. This monument is one of the most underrated places to visit in Ceske Budejovice. Next, head to Black Tower, a worthwhile monument, known for its culturally significant features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to The State Chateau Of Hluboká. This instagrammable castle is a highly recommended experience. Nearby, you'll also find Ohrada Zoo and Castle Blatná. Visit these for an interesting touch to your journey.

At the end of the day, you will drive to Plzeň, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Plzeň. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Raven Pub City, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Restaurace & Hotel U Salzmannů is another top choice with a popular menu. You could also check for a table at Pláž OSTENDE BOLEVÁK. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Plzeň tonight.

Let the evening flow smoothly from dinner to drinks at Francis - Beer Café, a top-rated bar in the area. For other recommendations, My Friends Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Beer Bar Pioneer offers a memorable night with diverse drink options and excellent service.

Relax and reminisce about your day in the Czech Republic and look forward to more memorable moments to come!

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Day 7

Day 7

  • Plzeň-City District
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Drive 8 km, 44 min

  • Plzeň Zoo
  • Cathedral of St. Bartholomew
  • Náměstí Republiky, Plzeň
  • Pilsner Urquell Brewery
  • More

On day 7 of your road trip, you will have an entire day to explore Plzeň. You’ll stay in Plzeň for 1 night and discover all the best things to see and do in the area.

A blend of family-friendly attractions, scenic views, and photo-friendly spots await you in Plzeň on today’s itinerary. First up is the popular zoo, Dinopark Plzeň. Afterward, continue to Cathedral Of St. Bartholomew, a church every traveler should visit.

As you explore Plzeň’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Náměstí Republiky, Plzeň. This increasingly popular public square is an essential stop. Following that, head to Pilsner Urquell Brewery, another must-visit site that will enhance your experience.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. The Czech Republic is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Plzeň. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Make sure to reserve a table at Mely Restaurant, an iconic dining spot in Plzeň. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Parkan, a popular restaurant in Plzeň. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Restaurace U Lízalky, a hidden gem nestled in Plzeň. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Cafe La Rose, Ltd. Stands out as an excellent choice for a post-dinner cocktail. Alternatively, Forest Bar offers an ideal atmosphere to enjoy the pleasures of the night. Vinyl Coffee & Pub is also a great option that provides a perfect setting for a relaxing evening.

Relax and reminisce about your day in the Czech Republic and look forward to more memorable moments to come!

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Day 8

Day 8

  • Plzeň-City District
  • Ústí nad Labem
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Drive 217 km, 4 hours 9 min

  • Loket Castle
  • Vřídelní kolonáda
  • Mill Colonnade
  • Diana Observation Tower
  • More

Experience an unparalleled adventure on day 8 of your road trip in the Czech Republic. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Loket and Carlsbad. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Ústí Nad Labem. You will spend 1 night here for some well-deserved relaxation.

Enjoy the perfect balance of relaxation and exploration in Plzeň today. One of the most captivating attractions included on the itinerary is Loket Castle. This standout castle will help you start your sightseeing on top. Then, take a leisurely stroll to Vřídelní Kolonáda and learn what makes this grand hot spring unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the locally renowned Mill Colonnade. After exploring the monument, head to Rozhledna Diana. This notable observation deck is a highlight in Plzeň.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Ústí Nad Labem. Ústí Nad Labem offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Ústí Nad Labem's best restaurants.

Dine in style at Restaurant Větruše, a top recommendation for dinner tonight. Or, for a change of pace, Hotel a Restaurant Větruše boasts a menu that's sure to impress. Also, be sure to check out BLACKSHEEP BAR. Known as a local hotspot, it’s a great choice for tonight in Ústí Nad Labem.

Extend your evening after a delightful meal by visiting Hp Bar, which offers the perfect atmosphere for a night out. Moreover, Ústecká Pivotéka is another popular option for a drink or two. Likewise, Pubs Bar Hamburg also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in the Czech Republic.

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Day 9

Day 9

  • Ústí nad Labem
  • Prague
  • More

Drive 199 km, 3 hours 16 min

  • Děčín Zoo
  • Kamenice Gorge
  • Bohemian Switzerland National Park
  • Mýdlárna Rubens
  • Labské pískovce Protected Landscape Area
  • More

On day 9 of your exciting self-drive vacation in the Czech Republic, you’ll soak in the magnificence of 4 destinations, Děčín, Mezná, Růžová, and Labská Stráň. When you’re not sightseeing, take time to relax at your selected hotel in Prague, where you’ll be staying for 1 night.

Get ready for a day filled with fun adventures, breathtaking views, and photo-friendly spots in the charming town of Ústí Nad Labem. Your adventure starts at Děčín Zoo, a curiosity-inducing local hot spot. Another notable attraction to explore is Kamenice Gorge. This underrated canyon is known for its breathtaking appeal.

After soaking in the highlights of these sights, take some time to wander Ústí Nad Labem's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to České Švýcarsko National Park. This serene national park offers a fascinating experience that many visitors find memorable. Mýdlárna Rubens is also worth visiting, along with Protected Landscape Area Elbe Sandstone Mountains. These standout landmarks offer unique experiences that add to the day’s enjoyment.

When you’re done exploring for the day, you’ll drive to your hotel in Prague. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of Prague's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a delicious meal at MAURIZIO restaurant & café, a highly-rated dining destination in Prague. If you're eager to try something different, consider Gate Restaurant, another top spot with a tantalizing menu. You might also want to secure a reservation at U Houmra. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Prague this evening.

After enjoying a fulfilling meal, continue your evening at Crazy Daisy, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Puerto Rico Cafe & Cocktail Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Anonymous Bar provides an excellent environment for a relaxed and enjoyable evening.

Say good night to Prague and look forward to another great day of your road trip in the Czech Republic!

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Day 10

Day 10

  • Prague - Departure day
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  • Clementinum
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Day 10 of your road trip in the Czech Republic is your departure day. This is your chance to catch a last glimpse of Prague before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Clementinum. This well-known library is a popular place to see in the city.

Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in the Czech Republic, drop by another restaurant for a last chance at a memorable dining experience in Prague.

If you're eager to try something different, consider The Grand Mark Prague, another top spot with a tantalizing menu.

You’ll then say farewell to Prague. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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