12-Day the Czech Republic Self-Drive Road Trip With Itinerary from Prague to Hradec Králové, Brno, Ceske Budejovice, and Plzeň and surrounding area

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Photo of famous Charles Bridge over the Vltava river in Prague, Czech Republic.
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Description

Experience the freedom of the open road on an unforgettable 12-day road trip in the Czech Republic! Embark on a self-drive tour that caters to every traveler, featuring destinations like Prague, Dvůr Králové nad Labem, Janské Lázně, Hradec Králové, Kutná Hora, Brno, Mikulov, Lednice, Jihlava, Ceske Budejovice, Hluboká nad Vltavou, Český Krumlov, Plzeň, Loket, Carlsbad, and Karlštejn.

This perfectly planned road trip itinerary takes you through some of the best places to see in the Czech Republic. You will spend 5 nights in Prague, 1 night in Hradec Králové, 2 nights in Brno, 1 night in Ceske Budejovice, and 2 nights in Plzeň. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Prague, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Prague Castle and Charles Bridge are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Prague, Dvůr Králové nad Labem, Janské Lázně, Hradec Králové, Kutná Hora, Brno, Mikulov, Lednice, Jihlava, Ceske Budejovice, Hluboká nad Vltavou, Český Krumlov, Plzeň, Loket, Carlsbad, and Karlštejn, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Travel details

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Flights

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Driver’s age is 30 - 65
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Pick-up: 10:00
Drop-off: 10:00

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Customize tours under each day and destination

Day 1

Day 1

  • Prague - Arrival day
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  • Letná Park
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Your road trip adventure in the Czech Republic begins as soon as you reach Prague and pick up your car. You’ll stay here for 4 nights and explore what to see in Prague, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Prague is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Prague. Check-in typically starts around 2 to 4 PM at hotels in the Czech Republic. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Raise a toast to the start of your 12-day road trip in the Czech Republic!

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Day 2

Day 2

  • Prague
  • More

Drive 15 km, 35 min

  • Old Town Square
  • Prague Astronomical Clock
  • Prague Zoo
  • Staré Město
  • Parizska Street
  • More

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Savor another day of unforgettable experiences in the Czech Republic!

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Day 3

Day 3

  • Prague
  • More

Drive 11 km, 1 hour 6 min

  • Petrin Tower
  • Lennon Wall
  • St. Vitus Cathedral
  • Prague Castle
  • Malá Strana
  • More

Day 3 offers an itinerary packed with the best things to see in Prague. You’ll stay in Prague for 2 nights more, offering you enough time to explore at a relaxed pace.

Set aside time today to explore Malá Strana, a standout neighborhood that reflects the essence of the city. While you're there, you'll also be within reach of some of the city's top landmarks, making it easy to maximize your day.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Prague. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Take some time to reflect on your day and savor another beautiful night in the Czech Republic.

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Day 4

Day 4

  • Prague
  • More

Drive 14 km, 1 hour 16 min

  • Vyšehrad
  • Dancing House
  • Franz Kafka - Rotating Head
  • Powder Tower
  • National Museum in Prague
  • More

You have 1 night left in Prague. Take the opportunity to experience more of the best attractions and activities in the city.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Prague. Enjoy a relaxing evening as you savor delicious local cuisine.

Relax and recharge in preparation for another adventurous day in the Czech Republic!

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Day 5

Day 5

  • Prague
  • Hradec Králové
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Drive 249 km, 3 hours 31 min

  • Dvůr Králové Zoo
  • Royal Forest Dam
  • The Timber Trail, Krkonoše
  • More

On day 5 of your exciting self-drive vacation in the Czech Republic, you’ll soak in the magnificence of 3 destinations, including Dvůr Králové nad Labem, Podháj, and Janské Lázně. When you’re not sightseeing, take time to relax at your chosen hotel in Hradec Králové, where you’ll be staying for 1 night.

At the end of the day, you will drive to Hradec Králové, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Hradec Králové, it's often a good idea to reserve a table in advance.

Raise your glass to another unforgettable day in the Czech Republic!

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Day 6

Day 6

  • Hradec Králové
  • Brno
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Drive 218 km, 3 hours 17 min

  • Jiráskovy sady
  • Sedlec Ossuary
  • Italian Court
  • St Barbara's Cathedral
  • More

On day 6 of your road trip in the Czech Republic, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Hradec Králové and Kutná Hora are on today's agenda. In the evening, you’ll end up in Brno, where you will stay for 2 nights.

Throughout the day, make sure to take breaks to appreciate the surroundings.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Brno. Brno offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Brno is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Brno.

Savor another day of unforgettable experiences in the Czech Republic!

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Day 7

Day 7

  • Brno
  • More

Drive 125 km, 2 hours 10 min

  • Mikulov Castle
  • Pálava Protected Landscape Area
  • Castle Lednice
  • Lednice–Valtice Cultural Landscape
  • Minaret
  • More

Wake up to day 7 of your road trip in the Czech Republic. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Mikulov and Lednice. With 1 night to stay in Brno, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

When you’re done exploring for the day, you’ll return to Brno and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Brno's best restaurants.

Savor another day of unforgettable experiences in the Czech Republic!

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Day 8

Day 8

  • Brno
  • České Budějovice
  • More

Drive 215 km, 3 hours 8 min

  • Náměstí Svobody
  • Špilberk Castle
  • Zoological Garden in Jihlava
  • More

Experience an unparalleled adventure on day 8 of your road trip in the Czech Republic. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Brno and Jihlava. At the end of the day, you will retreat to the hotel of your choice in Ceske Budejovice, where will spend 1 night.

When you’re done exploring for the day, you’ll drive to your hotel in Ceske Budejovice. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Ceske Budejovice's most popular restaurants, and connect with friendly locals for a true cultural experience.

Head back to your accommodation in Ceske Budejovice and get some rest to prepare for another magical day of your road trip in the Czech Republic.

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Day 9

Day 9

  • České Budějovice
  • Plzeň-City District
  • More

Drive 208 km, 3 hours 32 min

  • Samson fountain
  • The State Chateau of Hluboká
  • Ohrada Zoo
  • State Castle and Chateau Český Krumlov
  • More

Dive into day 9 of your remarkable road trip in the Czech Republic. Today you'll explore 3 destinations, including Ceske Budejovice, Hluboká nad Vltavou, and Český Krumlov. At the end of the day, you’ll unwind at one of the finest accommodations in Plzeň, where you'll spend 2 nights.

At the end of the day, you will drive to Plzeň, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Plzeň's best restaurants.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in the Czech Republic.

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Day 10

Day 10

  • Plzeň-City District
  • More

Drive 171 km, 3 hours 39 min

  • Loket Castle
  • Park Colonnade
  • Mill Colonnade
  • Vřídelní kolonáda
  • Diana Observation Tower
  • More

On day 10 of your road trip, you’ll start and end your day in Plzeň, where you have 1 night left to stay.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Plzeň.

Plzeň is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Plzeň.

Celebrate another amazing day of your road trip adventure in the Czech Republic!

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Day 11

Day 11

  • Plzeň-City District
  • Prague
  • More

Drive 119 km, 2 hours 11 min

  • Cathedral of St. Bartholomew
  • Pilsner Urquell Brewery
  • Plzeň Zoo
  • Karlštejn Castle
  • More

Your itinerary for day 11 of your road trip in the Czech Republic includes 2 stops and features some of the highlights of Plzeň and Karlštejn. At the end of the day, enjoy the comforts of a top-rated hotel in Prague, where you'll spend 1 night.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Prague. Prague offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Prague. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Relax and recharge in preparation for another adventurous day in the Czech Republic!

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Day 12

Day 12

  • Prague - Departure day
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  • Charles Bridge
  • More

Day 12 of your road trip in the Czech Republic is your departure day. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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How it works

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

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