Two-Week the Czech Republic Self-Drive Road Trip With Itinerary from Prague to Liberec, Ústí Nad Labem, Carlsbad, and Plzeň and surrounding area

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Photo of famous Charles Bridge over the Vltava river in Prague, Czech Republic.
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Explore the best of the Czech Republic on a remarkable 15-day road trip! Combine exploration with relaxation on a self-drive tour featuring Prague, Průhonice, Křivoklát, Mělník, Jestřebice, Dvůr Králové nad Labem, Trutnov, Liberec, Sychrov, Sloup v Čechách, Kamenický Šenov, Děčín, Labská Stráň, Ústí Nad Labem, Most, Chomutov, Carlsbad, Plzeň, Nová Ves, Bečov nad Teplou, Loket, Mariánské Lázně, and Karlštejn.

This perfectly planned road trip itinerary takes you through some of the best places to see in the Czech Republic. You will spend 7 nights in Prague, 2 nights in Liberec, 1 night in Ústí Nad Labem, 1 night in Carlsbad, and 3 nights in Plzeň. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Prague, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Prague Castle and Charles Bridge are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Prague, Průhonice, Křivoklát, Mělník, Jestřebice, Dvůr Králové nad Labem, Trutnov, Liberec, Sychrov, Sloup v Čechách, Kamenický Šenov, Děčín, Labská Stráň, Ústí Nad Labem, Most, Chomutov, Carlsbad, Plzeň, Nová Ves, Bečov nad Teplou, Loket, Mariánské Lázně, and Karlštejn, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day 1

Day 1

  • Prague - Arrival day
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  • Franz Kafka - Rotating Head
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Welcome to Prague, the perfect starting point for your road trip in the Czech Republic! Pick up your rental car and let the adventure begin. You will spend 6 nights discovering what to see in Prague before embarking on the next leg of your journey.

Prague is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Prague. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in the Czech Republic. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Raise a toast to the start of your 15-day road trip in the Czech Republic!

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Day 2

Day 2

  • Prague
  • More

Drive 16 km, 59 min

  • Prague Zoo
  • Powder Tower
  • Old Town Square
  • Prague Astronomical Clock
  • Charles Bridge
  • More

Day 2 offers an itinerary packed with the best things to see in Prague. You’ll stay in Prague for 5 nights more, offering you enough time to explore at a relaxed pace.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

Prague is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Prague.

Raise your glass to another unforgettable day in the Czech Republic!

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Day 3

Day 3

  • Prague
  • More

Drive 7 km, 1 hour 17 min

  • Prague Castle
  • St. Vitus Cathedral
  • Lennon Wall
  • National Theatre
  • Dancing House
  • More

You’ll stay in Prague for 4 nights.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Prague's most popular restaurants, and connect with friendly locals for a true cultural experience.

Say good night to Prague and look forward to another great day of your road trip in the Czech Republic!

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Day 4

Day 4

  • Prague
  • More

Drive 15 km, 1 hour 15 min

  • National Technical Museum
  • Letná Park
  • National Museum in Prague
  • Náměstí Míru
  • Vyšehrad
  • More

You have 3 nights left in Prague. Take the opportunity to experience more of the best attractions and activities in the city.

Throughout the day, make sure to take breaks to appreciate the surroundings.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Prague. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Head back to your accommodation in Prague and get some rest to prepare for another magical day of your road trip in the Czech Republic.

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Day 5

Day 5

  • Prague
  • More

Drive 160 km, 2 hours 20 min

  • Park Průhonice
  • Křivoklát Castle
  • Malá Strana
  • Parizska Street
  • More

On day 5 of your road trip, you’ll start and end your day in Prague, where you still have 2 nights left. You'll spend part of the day exploring places of interest outside the immediate city, including Průhonice and Křivoklát.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Prague.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Prague. Enjoy a relaxing evening as you savor delicious local cuisine.

Relax and recharge in preparation for another adventurous day in the Czech Republic!

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Day 6

Day 6

  • Prague
  • More

Drive 151 km, 2 hours 35 min

  • Chráněná krajinná oblast Kokořínsko - Máchův kraj
  • Pokličky
  • Castle Kokorin
  • More

Greet day 6 of your road trip in the Czech Republic with a smile and start your day with a hearty breakfast. You have 1 night to stay in Prague, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Mělník, Jestřebice, and Kokořínský Důl.

When you’re done exploring for the day, you’ll return to Prague and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Prague. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Relax and look forward to more memorable moments to come!

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Day 7

Day 7

  • Prague
  • Liberec
  • More

Drive 271 km, 4 hours 8 min

  • Dvůr Králové Zoo
  • Royal Forest Dam
  • Krkonoše National Park
  • More

Dive into day 7 of your remarkable road trip in the Czech Republic. Today you'll explore 3 destinations, including Dvůr Králové nad Labem, Podháj, and Trutnov. At the end of the day, you’ll unwind at one of the finest accommodations in Liberec, where you'll spend 2 nights.

At the end of the day, you will drive to Liberec, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Liberec's most popular restaurants, and connect with friendly locals for a true cultural experience.

Head back to your accommodation in Liberec and get some rest to prepare for another magical day of your road trip in the Czech Republic.

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Day 8

Day 8

  • Liberec
  • More

Drive 45 km, 47 min

  • Liberec Town Hall
  • DinoPark Liberec Plaza
  • Sychrov Castle
  • More

On day 8 of your road trip, you’ll start and end your day in Liberec, where you have 1 night left to stay.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Liberec.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Liberec, it's often a good idea to reserve a table in advance.

Get a good night's sleep and look forward to another great day on the road in the Czech Republic!

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Day 9

Day 9

  • Liberec
  • Ústí nad Labem
  • More

Drive 146 km, 3 hours 3 min

  • Rock Castle Sloup
  • Mansion Rock (basalt columns)
  • Bohemian Switzerland National Park
  • Labské pískovce Protected Landscape Area
  • Děčín Zoo
  • More

Experience an unparalleled adventure on day 9 of your road trip in the Czech Republic. This exciting part of your journey invites you to discover the renowned landmarks in 4 places, which are Sloup v Čechách, Kamenický Šenov, Děčín, and Labská Stráň. At the end of the day, you will retreat to the hotel of your choice in Ústí Nad Labem, where will spend 1 night.

When you’re done exploring for the day, you’ll drive to your hotel in Ústí Nad Labem. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Ústí Nad Labem. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Savor another day of unforgettable experiences in the Czech Republic!

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Day 10

Day 10

  • Ústí nad Labem
  • Carlsbad
  • More

Drive 129 km, 2 hours 5 min

  • Ústí nad Labem Zoo
  • Hněvín
  • Chomutov Zoo
  • More

On day 10 of your exciting self-drive vacation in the Czech Republic, you’ll soak in the magnificence of 3 destinations, including Ústí Nad Labem, Most, and Chomutov. When you’re not sightseeing, take time to relax at your chosen hotel in Carlsbad, where you’ll be staying for 1 night.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Carlsbad. Carlsbad offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Carlsbad's best restaurants.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in the Czech Republic.

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Day 11

Day 11

  • Carlsbad
  • Plzeň-City District
  • More

Drive 79 km, 2 hours 31 min

  • Park Colonnade
  • Mill Colonnade
  • Vřídelní kolonáda
  • Saint Peter and Paul Cathedral
  • Diana Observation Tower
  • More

Your itinerary for day 11 of your road trip in the Czech Republic includes 1 stop and features some of the highlights of Carlsbad. At the end of the day, enjoy the comforts of a top-rated hotel in Plzeň, where you'll spend 3 nights.

At the end of the day, you will drive to Plzeň, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Plzeň is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Plzeň.

As the sun sets, rest up and recharge for the next leg of your road trip in the Czech Republic.

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Day 12

Day 12

  • Plzeň-City District
  • More

Drive 175 km, 2 hours 52 min

  • Slavkov forest
  • State Castle Bečov
  • Loket Castle
  • More

Wake up to day 12 of your road trip in the Czech Republic. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Nová Ves, Bečov nad Teplou, and Loket. With 2 nights to stay in Plzeň, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

When you’re done exploring for the day, you’ll return to Plzeň and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Plzeň's best restaurants.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in the Czech Republic.

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Day 13

Day 13

  • Plzeň-City District
  • More

Drive 145 km, 2 hours 56 min

  • Zpívající fontána
  • Ski resort Mariánky
  • Park Boheminium Mariánské Lázně
  • More

On day 13 of your road trip in the Czech Republic, you’ll start and end your day in Plzeň, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Plzeň, there’s no need to rush. Experience Mariánské Lázně to the fullest today with this curated day itinerary.

Throughout the day, make sure to take breaks to appreciate the surroundings.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Plzeň.

Plzeň is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Plzeň.

Savor another day of unforgettable experiences in the Czech Republic!

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Day 14

Day 14

  • Plzeň-City District
  • Prague
  • More

Drive 119 km, 2 hours 11 min

  • Cathedral of St. Bartholomew
  • Pilsner Urquell Brewery
  • Plzeň Zoo
  • Karlštejn Castle
  • More

On day 14 of your road trip in the Czech Republic, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Plzeň and Karlštejn are on today's agenda. In the evening, you’ll end up in Prague, where you will stay for 1 night.

When you’re done exploring for the day, you’ll drive to your hotel in Prague. Check in and relax before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Say good night to Prague and look forward to another great day of your road trip in the Czech Republic!

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Day 15

Day 15

  • Prague - Departure day
  • More
  • Clementinum
  • More

Day 15 of your road trip in the Czech Republic is your departure day. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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