4-Day the Czech Republic Self-Drive Road Trip With Itinerary from Brno to Prague

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Escape the ordinary with this exciting 4-day road trip through the Czech Republic. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in the Czech Republic takes you through some of the best places to see in the country. You will spend 2 nights in Brno and 1 night in Prague. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Brno, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Charles Bridge and Prague Astronomical Clock are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Špilberk Castle, learn more about the unique Náměstí Svobody, and immerse yourself in the vibrant atmosphere of The Castle Garden.

As you hit the open road and drive through Brno, Telč, Prague, Český Krumlov, and Třeboň, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Špilberk Castle
Villa TugendhatTelč châteauCharles BridgePrague Astronomical Clock
Český Krumlov Castle TowerThe Castle GardenTřeboň v marcipánu
Náměstí Svobody

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Day 1

Day 1

  • Brno - Arrival day
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  • Špilberk Castle
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Say hello to Brno! Your exciting road trip through the Czech Republic is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Brno for 1 night before you continue your adventure!

Brno is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Špilberk Castle, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Brno. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brno, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at U Štíra, an iconic dining spot in Brno. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bistro Franz, a popular restaurant in Brno. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Noem Arch Restaurant, a hidden gem nestled in Brno. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Following your dinner, dive into the local bar culture at Bar Naproti. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Super Panda Circus, the perfect place for those looking to experience the best of the nightlife. Similarly, Výčep Na Stojáka provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Raise a toast to the start of your 4-day road trip in the Czech Republic!

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Day 2

Day 2

  • Brno
  • Prague
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Drive 280 km, 3 hours 55 min

  • Villa Tugendhat
  • Telč château
  • Charles Bridge
  • Prague Astronomical Clock
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Dive into day 2 of your remarkable road trip in the Czech Republic. Today you will explore Brno, Telč, and Prague, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Prague. You’ll stay here for 1 night.

Prepare for a day full of fun adventures, scenic views, and picturesque spots. When you’re ready, kick off your sightseeing adventure at Villa Tugendhat. This frequently visited museum is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Telč Château, one of the city’s best highlights.

Next, check out Charles Bridge, one of the most iconic places to see in Brno. This historical landmark is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Prague Astronomical Clock. Wander around and soak in the grand atmosphere this historical landmark offers.

When you’re done exploring for the day, you’ll drive to your hotel in Prague. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Prague's best restaurants.

Don’t miss out on dining at U Tellerů, a top-rated dining destination in Prague. If you're in the mood to try something new, consider Restaurace U Bansethů, another top spot with a mouthwatering menu. You might also want to secure a reservation at Eska Restaurant and Bakery. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Prague this evening.

Unwind after your meal by stepping into Anonymous Shrink's Office. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Bar No. 7 - Prague offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Kontakt Bar, another top-rated bar in the area.

Say good night to Prague and look forward to another great day of your road trip in the Czech Republic!

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Day 3

Day 3

  • Prague
  • Brno
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Drive 418 km, 5 hours 41 min

  • Český Krumlov Castle Tower
  • The Castle Garden
  • Třeboň v marcipánu
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Experience an unparalleled adventure on day 3 of your road trip in the Czech Republic. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Český Krumlov and Třeboň. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Brno. You will spend 1 night here for some well-deserved relaxation.

Bring your curiosity for today’s adventure around Prague. Some of the town’s most loved attractions await! Český Krumlov Castle Tower is the perfect place to start. This castle is one of the most intriguing places to visit in Prague. Next, head to The Castle Garden, an often recommended castle, known for its visually striking features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Třeboň V Marcipánu. This eye-catching museum is a highly recommended experience. Visit these for an interesting touch to your journey.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Brno. Brno offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Brno. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Nok Nok Restaurace Brno, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Sportovní areál Komec? It's another excellent option with a diverse menu. Consider reserving a table at Restaurace L'Eau Vive as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Brno.

Cap off your dinner by heading to Jazzový Bar U Kouřícího Králíka, ideal for a leisurely evening with a drink in hand. Queen Luxury Hookah Club is another bar that offers an enjoyable setting. Similarly, Shot Bar is also a popular place to go on a night out, perfect for relaxing and socializing.

Celebrate another amazing day of your road trip adventure in the Czech Republic!

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Day 4

Day 4

  • Brno - Departure day
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  • Náměstí Svobody
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Day 4 of your road trip in the Czech Republic is your departure day. This is your chance to catch a last glimpse of Brno before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Náměstí Svobody, a romantic public square before you head out.

Maximize your last day in the Czech Republic and go on a shopping spree in Brno’s shopping center, the lively Avion Shopping Park. Browse for souvenirs to remind you of your wonderful journey in the Czech Republic.

Before you conclude your road trip in the Czech Republic, drop by another restaurant for a last chance at a memorable dining experience in Brno.

You’ll then say farewell to Brno. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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