4-Day the Czech Republic Self-Drive Road Trip With Itinerary from Brno to Prague

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Photo of amazing view of the old town and Cathedral of St. Peter and Paul in Brno, Czech Republic.
Photo of building in Denis Gardens in the center of Brno city, Czech Republic.
4-Day the Czech Republic Self-Drive Road Trip With Itinerary from Brno to Prague
4-Day the Czech Republic Self-Drive Road Trip With Itinerary from Brno to Prague
4-Day the Czech Republic Self-Drive Road Trip With Itinerary from Brno to Prague
4-Day the Czech Republic Self-Drive Road Trip With Itinerary from Brno to Prague
4-Day the Czech Republic Self-Drive Road Trip With Itinerary from Brno to Prague
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Explore the best of the Czech Republic on a remarkable 4-day road trip! Combine exploration with relaxation on a self-drive tour featuring Brno, Telč, Prague, Český Krumlov, and Třeboň.

This perfectly planned road trip itinerary takes you through some of the best places to see in the Czech Republic. You will spend 2 nights in Brno and 1 night in Prague. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Brno, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Charles Bridge and Prague Astronomical Clock are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Brno, Telč, Prague, Český Krumlov, and Třeboň, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day1

Day 1

  • Brno - Arrival day
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  • Špilberk Castle
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Welcome to Brno, the perfect starting point for your road trip in the Czech Republic! Pick up your rental car and let the adventure begin. You will spend 1 night discovering what to see in Brno before embarking on the next leg of your journey.

Brno is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Špilberk Castle. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Brno. Check-in typically starts around 2 to 4 PM at hotels in the Czech Republic. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brno, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at U Štíra, a highly-rated dining destination in Brno. If you're eager to try something different, consider Bistro Franz, another top spot with a tantalizing menu. You might also want to secure a reservation at Noem Arch Restaurant. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Brno this evening.

Cap off your dinner by heading to Bar Naproti, ideal for a leisurely evening with a drink in hand. Super Panda Circus is another bar that offers an enjoyable setting. Similarly, Výčep Na Stojáka is also a popular place to go on a night out, perfect for relaxing and socializing.

Raise a toast to the start of your 4-day road trip in the Czech Republic!

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Day2

Day 2

  • Brno
  • Telč
  • Prague
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Drive 280 km, 3 hours 55 min

  • Villa Tugendhat
  • Telč château
  • Charles Bridge
  • Prague Astronomical Clock
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Your itinerary for day 2 of your road trip in the Czech Republic includes 3 stops and features some of the highlights of Brno, Telč, and Prague. At the end of the day, enjoy the comforts of a top-rated hotel in Prague, where you'll spend 1 night.

Make a stop at Villa Tugendhat. This worthwhile museum is a must-visit for travelers looking for a unique holiday experience.

Set your GPS to Telč and hit the road. Expect a journey of approximately 1 hour 31 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Telč beckons with new experiences!

For a more meaningful self-guided tour of the city's best attractions, visit Telč Château, a frequently visited castle that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Prague may take around 2 hours. Upon your arrival in Prague, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Charles Bridge, a timeless historical landmark that everyone visiting Prague should see. Next, head to Prague Astronomical Clock. This romantic historical landmark is one of the most famous attractions in the region.

When you’re done exploring for the day, you’ll drive to your hotel in Prague. Check in and relax before you head out to tour the city.

Prague is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Prague.

Make sure to reserve a table at U Tellerů, an iconic dining spot in Prague. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Restaurace U Bansethů, a popular restaurant in Prague. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Eska Restaurant and Bakery, a hidden gem nestled in Prague. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Extend your evening after a delightful meal by visiting Anonymous Shrink's Office, which offers the perfect atmosphere for a night out. Moreover, Bar No. 7 - Prague is another popular option for a drink or two. Likewise, Kontakt Bar also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

As the sun sets, rest up and recharge for the next leg of your road trip in the Czech Republic.

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Day3

Day 3

  • Prague
  • Český Krumlov
  • Třeboň
  • Brno
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Drive 418 km, 5 hours 41 min

  • Český Krumlov Castle Tower
  • The Castle Garden
  • Třeboň v marcipánu
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Experience an unparalleled adventure on day 3 of your road trip in the Czech Republic. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Český Krumlov and Třeboň. At the end of the day, you will retreat to the hotel of your choice in Brno, where will spend 1 night.

Set your GPS to Český Krumlov and hit the road. Expect a journey of approximately 2 hours 15 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Český Krumlov beckons with new experiences!

Our first attraction recommendation in Český Krumlov is Český Krumlov Castle Tower, a frequently visited castle that draws attention for its enchanting features. Spend some time soaking in the atmosphere before continuing to The Castle Garden, an UNESCO world heritage-designated castle that stands out in the town.

After soaking in Český Krumlov’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Třeboň. Expect your car journey to take a minimum of 52 min. When you arrive in Třeboň, it's time to take a break from the road.

Our first attraction recommendation in Třeboň is Třeboň V Marcipánu, an underrated museum that draws attention for its picture-perfect features.

At the end of the day, you will drive to Brno, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brno, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at Nok Nok Restaurace Brno, a popular restaurant in Brno. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Brno at Sportovní areál Komec, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Restaurace L'Eau Vive. It’s yet another ideal choice to enhance your time in Brno tonight.

Following your dinner, dive into the local bar culture at Jazzový Bar U Kouřícího Králíka. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Queen Luxury Hookah Club, the perfect place for those looking to experience the best of the nightlife. Similarly, Shot Bar provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Relax and recharge in preparation for another adventurous day in the Czech Republic!

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Day4

Day 4

  • Brno - Departure day
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  • Náměstí Svobody
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Day 4 of your road trip in the Czech Republic is your departure day. This is your chance to catch a last glimpse of Brno before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Náměstí Svobody. This locally renowned public square is a hotspot among locals.

Take advantage of your accommodation's proximity to Brno’s shopping district for some last-minute bargain hunting. Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in the Czech Republic, drop by another restaurant for a last chance at a memorable dining experience in Brno.

If you're eager to try something different, consider Valoria, another top spot with a tantalizing menu.

You’ll then say farewell to Brno. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

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