4-Day the Czech Republic Self-Drive Road Trip With Itinerary from Prague to Plzeň and surrounding area

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Photo of famous Charles Bridge over the Vltava river in Prague, Czech Republic.
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Experience the freedom of the open road on an unforgettable 4-day road trip in the Czech Republic! Embark on a self-drive tour that caters to every traveler, featuring destinations like Prague, Plzeň, Koněprusy, and Karlštejn.

This perfectly planned road trip itinerary takes you through some of the best places to see in the Czech Republic. You will spend 2 nights in Prague and 1 night in Plzeň. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Prague, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Prague Castle and Charles Bridge are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Old Town Square, learn more about the unique St. Vitus Cathedral, and immerse yourself in the vibrant atmosphere of Prague Astronomical Clock.

As you hit the open road and drive through Prague, Plzeň, Koněprusy, and Karlštejn, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
Drop-off: 10:00

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Day 1

Day 1

  • Prague - Arrival day
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  • Dancing House
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Your road trip adventure in the Czech Republic begins as soon as you reach Prague and pick up your car. You’ll stay here for 1 night and explore what to see in Prague, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Prague is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Dancing House, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Prague. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at U Tellerů, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Restaurace U Bansethů? It's another excellent option with a diverse menu. Consider reserving a table at Eska Restaurant and Bakery as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Prague.

If you’re not ready to end the night just yet, Anonymous Shrink's Office offers a perfect venue to relax and savor a drink. Similarly, Bar No. 7 - Prague is well-suited for those looking to unwind in a social setting. Kontakt Bar is another excellent spot to enjoy a nightcap after a delightful meal.

Raise a toast to the start of your 4-day road trip in the Czech Republic!

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Day 2

Day 2

  • Prague
  • Plzeň-City District
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Drive 103 km, 1 hour 47 min

  • Old Town Square
  • Prague Astronomical Clock
  • Vyšehrad
  • Prague Castle
  • St. Vitus Cathedral
  • More

Experience an unparalleled adventure on day 2 of your road trip in the Czech Republic. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Prague. At the end of the day, you will retreat to the hotel of your choice in Plzeň, where will spend 1 night.

Catch Old Town Square before the crowds roll in. This visually striking public square is sure to ignite your curiosity. Next, dive into the enchanting features of Prague Astronomical Clock, a must-visit historical landmark in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Vyšehrad, a popular castle. For a change of scene, check out Prague Castle, known for its majestic features. We also recommend visiting St. Vitus Cathedral. This church is a must for anyone looking to experience the city to the fullest.

When you’re done exploring for the day, you’ll drive to your hotel in Plzeň. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Plzeň. Enjoy a relaxing evening as you savor delicious local cuisine.

Make sure to reserve a table at Raven Pub City, an iconic dining spot in Plzeň. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Restaurace & Hotel U Salzmannů, a popular restaurant in Plzeň. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Pláž OSTENDE BOLEVÁK, a hidden gem nestled in Plzeň. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Keep the evening going at Francis - Beer Café, a great choice for enjoying the after-dinner hours with a drink. You could also go to My Friends Bar, which offers a similarly pleasant setting and great drinks. Another option is Beer Bar Pioneer, which provides an inviting environment for unwinding after a busy day out.

Say good night to Plzeň and look forward to another great day of your road trip in the Czech Republic!

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Day 3

Day 3

  • Plzeň-City District
  • Prague
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Drive 117 km, 2 hours 38 min

  • Pilsner Urquell Brewery
  • Plzeň Zoo
  • Koněpruské Caves
  • Chráněná krajinná oblast Český kras
  • Karlštejn Castle
  • More

Dive into day 3 of your remarkable road trip in the Czech Republic. Today you'll explore 3 destinations, including Plzeň, Koněprusy, and Karlštejn. At the end of the day, you’ll unwind at one of the finest accommodations in Prague, where you'll spend 1 night.

Pilsner Urquell Brewery makes a great addition to your morning plans. This underrated brewery is an instagrammable place to see in Plzeň. Continue your discovery at Dinopark Plzeň, an instagrammable zoo with stories to tell.

As you stroll around Plzeň, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Koněprusy Caves. This increasingly popular cave system offers a history-steeped encounter with Plzeň. Next, make your way to Chráněná Krajinná Oblast Český Kras to add another highlight to your day. After that, visit Karlštejn Castle, a notable castle that’s sure to impress. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Plzeň.

At the end of the day, you will drive to Prague, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Brasileiro Restaurant, an iconic dining spot in Prague. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Restaurant Meat Beer, a popular restaurant in Prague. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Restaurace Století, a hidden gem nestled in Prague. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue the enjoyment post-dinner at Bowla Bar, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, The Saints offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Beergeek Bar. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Relax and recharge in preparation for another adventurous day in the Czech Republic!

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Day 4

Day 4

  • Prague - Departure day
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  • Charles Bridge
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Day 4 of your road trip in the Czech Republic is your departure day. This is your chance to catch a last glimpse of Prague before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Charles Bridge, an enchanting historical landmark before you head out.

For a last-minute shopping spree in Prague, Wenceslas Square is nearby. Enjoy a variety of retail stores, dining options, and essential services in one convenient location.

Before you conclude your road trip in the Czech Republic, drop by another restaurant for a last chance at a memorable dining experience in Prague.

Treat yourself to a delightful dinner at BeBop Bar, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Café restaurant Palanda? It's another excellent option with a diverse menu.

You’ll then say farewell to Prague. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

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