5-Day the Czech Republic Self-Drive Road Trip With Itinerary from Brno traveling west to Prague

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Photo of amazing view of the old town and Cathedral of St. Peter and Paul in Brno, Czech Republic.
Photo of building in Denis Gardens in the center of Brno city, Czech Republic.
5-Day the Czech Republic Self-Drive Road Trip With Itinerary from Brno traveling west to Prague
5-Day the Czech Republic Self-Drive Road Trip With Itinerary from Brno traveling west to Prague
5-Day the Czech Republic Self-Drive Road Trip With Itinerary from Brno traveling west to Prague
5-Day the Czech Republic Self-Drive Road Trip With Itinerary from Brno traveling west to Prague
5-Day the Czech Republic Self-Drive Road Trip With Itinerary from Brno traveling west to Prague
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Escape the ordinary with this exciting 5-day road trip through the Czech Republic. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in the Czech Republic. You will spend 2 nights in Brno and 2 nights in Prague. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Brno, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Prague Castle and Charles Bridge are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Brno, Prague, Karlštejn, and Telč, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day1

Day 1

  • Brno - Arrival day
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  • Špilberk Castle
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Say hello to Brno! Your exciting road trip through the Czech Republic is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Brno for 1 night before you continue your adventure!

Brno is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Špilberk Castle. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Brno. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in the Czech Republic. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brno, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at U Štíra, an iconic dining spot in Brno. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bistro Franz, a popular restaurant in Brno. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Noem Arch Restaurant, a hidden gem nestled in Brno. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

To truly maximize your evening out, consider visiting Bar Naproti after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Super Panda Circus, another bar with an inviting ambiance. Similarly, Výčep Na Stojáka also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Raise a toast to the start of your 5-day road trip in the Czech Republic!

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Day2

Day 2

  • Brno
  • Prague
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Drive 212 km, 2 hours 33 min

  • Vyšehrad
  • Charles Bridge
  • Prague Astronomical Clock
  • Old Town Square
  • More

On day 2 of your road trip in the Czech Republic, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Prague are on today's agenda. In the evening, you’ll end up in Prague, where you will stay for 2 nights.

As you explore Prague’s charming streets, take in the lively atmosphere and get to know the character of the city.

When you’re ready to jump back into the car and say goodbye to Brno, you’ll hit the road in the direction of Prague. This drive usually takes around 2 hours 4 min.

Spend your afternoon discovering Vyšehrad, a popular castle known for its enchanting features. Next, continue your sightseeing at Charles Bridge, a world-famous historical landmark.

If you're starting to feel hungry, this is a great time for a break at a nearby restaurant or cafe. When you're ready for more, stop by Prague Astronomical Clock and uncover the details of this grand historical landmark. Make sure to also explore Old Town Square, a world-famous public square.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Prague. Prague offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Prague's best restaurants.

Have a fantastic dining experience at U Tellerů, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Restaurace U Bansethů offers an enticing alternative with its varied menu. Additionally, Eska Restaurant and Bakery is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Prague.

Let the evening flow smoothly from dinner to drinks at Anonymous Shrink's Office, a top-rated bar in the area. For other recommendations, Bar No. 7 - Prague provides a perfect setting for rounding out your night with style and great drinks. Likewise, Kontakt Bar offers a memorable night with diverse drink options and excellent service.

Head back to your accommodation in Prague and get some rest to prepare for another magical day of your road trip in the Czech Republic.

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Day3

Day 3

  • Prague
  • Karlštejn
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Drive 76 km, 1 hour 57 min

  • Karlštejn Castle
  • St. Vitus Cathedral
  • Prague Castle
  • Dancing House
  • Powder Tower
  • Malá Strana
  • More

On day 3 of your road trip, you’ll start and end your day in Prague, where you have 1 night left to stay.

One of the most iconic spots you can visit today is Malá Strana. Allow yourself some time to explore this neighborhood and discover its unique quirks. You'll also find many of the best sightseeing spots nearby.

One of the most famous attractions included on the itinerary is St. Vitus Cathedral. This romantic church will help you start your sightseeing on top. Then, take a leisurely stroll to Prague Castle and learn what makes this romantic castle unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the top-rated Dancing House. After exploring the art installation, head to Powder Tower. This notable monument is a highlight in Prague.

Spend your afternoon discovering Karlštejn Castle, an interesting castle known for its awe-inspiring features.

When you’re done exploring for the day, you’ll return to Prague and your accommodation.

Indulge in a memorable dining experience at one of Prague's most popular restaurants, and connect with friendly locals for a true cultural experience.

Make sure to reserve a table at Brasileiro Restaurant, an iconic dining spot in Prague. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Restaurant Meat Beer, a popular restaurant in Prague. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Restaurace Století, a hidden gem nestled in Prague. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Let the evening flow smoothly from dinner to drinks at Bowla Bar, a top-rated bar in the area. For other recommendations, The Saints provides a perfect setting for rounding out your night with style and great drinks. Likewise, Beergeek Bar offers a memorable night with diverse drink options and excellent service.

Say good night to Prague and look forward to another great day of your road trip in the Czech Republic!

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Day4

Day 4

  • Prague
  • Telč
  • Brno
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Drive 285 km, 3 hours 55 min

  • Zámecká Zahrada
  • Telč château
  • Zacharias of Hradec Square
  • Telč House
  • Rozhledna Oslednice
  • More

On day 4 of your exciting self-drive vacation in the Czech Republic, you’ll soak in the magnificence of 1 destination, including Telč. When you’re not sightseeing, take time to relax at your chosen hotel in Brno, where you’ll be staying for 1 night.

Embrace the thrill of the open road as you wave goodbye to Prague and set your GPS to Telč. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 1 hour 54 min. Upon reaching Telč, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

One of our top recommendations for your sightseeing is Castle Garden. Spend some time admiring the visually striking features of the castle before you continue to your next stop. Then, head to Telč Château. This increasingly popular castle is a traveler-favorite in the town.

If you're keen to see more, continue to Zacharias Of Hradec Square. Feed your curiosity by learning something new about the public square. Next, take your journey to Telč, a frequently visited museum. Conclude your sightseeing at Observation Tower Oslednice, known for its gorgeous features.

When you’re done exploring for the day, you’ll drive to your hotel in Brno. Check in and relax before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brno, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Nok Nok Restaurace Brno, a top-rated dining destination in Brno. If you're in the mood to try something new, consider Sportovní areál Komec, another top spot with a mouthwatering menu. You might also want to secure a reservation at Restaurace L'Eau Vive. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Brno this evening.

To truly maximize your evening out, consider visiting Jazzový Bar U Kouřícího Králíka after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Queen Luxury Hookah Club, another bar with an inviting ambiance. Similarly, Shot Bar also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Savor another day of unforgettable experiences in the Czech Republic!

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Day5

Day 5

  • Brno - Departure day
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  • Masarykova Street
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Day 5 of your road trip in the Czech Republic is your departure day. This is your chance to catch a last glimpse of Brno before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

One of the best things to do on your last day is to explore Masarykova Street, a street that you shouldn't miss while in Brno. Take your time to uncover its best sides and enjoy its proximity to many of the area’s best attractions.

For a shopping spree in Brno, we recommend the lively Avion Shopping Park. Here, you'll find a range of shops you can browse for some souvenir shopping.

Before you conclude your road trip in the Czech Republic, drop by another restaurant for a last chance at a memorable dining experience in Brno.

Enjoy a lovely meal at HOTEL INTERNATIONAL BRNO, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Valoria is another top choice with a popular menu.

You’ll then say farewell to Brno. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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