5-Day the Czech Republic Self-Drive Road Trip With Itinerary from Brno traveling west to Prague

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Escape the ordinary with this exciting 5-day road trip through the Czech Republic. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in the Czech Republic takes you through some of the best places to see in the country. You will spend 2 nights in Brno and 2 nights in Prague. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Brno, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Prague Castle and Charles Bridge are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Old Town Square, learn more about the unique St. Vitus Cathedral, and immerse yourself in the vibrant atmosphere of Prague Astronomical Clock.

As you hit the open road and drive through Brno, Prague, Karlštejn, and Telč, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Špilberk Castle
VyšehradCharles BridgePrague Astronomical ClockOld Town Square
Karlštejn CastleSt. Vitus CathedralPrague CastleDancing HousePowder TowerMalá Strana
Zámecká ZahradaTelč châteauZacharias of Hradec SquareTelč HouseRozhledna Oslednice
Masarykova Street

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Day 1

Day 1

  • Brno - Arrival day
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  • Špilberk Castle
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Welcome to Brno, the perfect starting point for your road trip in the Czech Republic! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Brno's charm before embarking on the next leg of your journey.

Brno is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Špilberk Castle, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Brno. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brno, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at U Štíra, an excellent option for tonight's dining. Looking for something different? Bistro Franz offers a tantalizing alternative with its diverse menu. And don’t miss Noem Arch Restaurant. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Brno.

Keep the excitement of the evening going by visiting a bar or two. Bar Naproti is an excellent place to start. You could also check out Super Panda Circus, offering a different kind of charm. A last recommendation for the day is Výčep Na Stojáka. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Raise a toast to the start of your 5-day road trip in the Czech Republic!

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Day 2

Day 2

  • Brno
  • Prague
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Drive 212 km, 2 hours 33 min

  • Vyšehrad
  • Charles Bridge
  • Prague Astronomical Clock
  • Old Town Square
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On day 2 of your exciting self-drive vacation in the Czech Republic, you’ll soak in the magnificence of 1 destination, Prague. When you’re not sightseeing, take time to relax at your selected hotel in Prague, where you’ll be staying for 2 nights.

Today, you'll explore some of the most beautiful places in Brno, including a castle, a historical landmark, and a public square. Start your day with a visit to Vyšehrad. This notable castle is a must-visit in the city. When you’re ready for your next discovery, continue to Charles Bridge, which may be one of the most history-steeped places you will experience today.

One of the best things about exploring Brno on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Prague Astronomical Clock, an astonishing historical landmark in the city. If you’re up for more discoveries, don’t forget to reserve some time for Old Town Square.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Prague. Prague offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Prague, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a delicious dinner at U Tellerů, an excellent option for tonight's dining. Looking for something different? Restaurace U Bansethů offers a tantalizing alternative with its diverse menu. And don’t miss Eska Restaurant and Bakery. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Prague.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Anonymous Shrink's Office stands out as an excellent choice for a post-dinner cocktail. Alternatively, Bar No. 7 - Prague offers an ideal atmosphere to enjoy the pleasures of the night. Kontakt Bar is also a great option that provides a perfect setting for a relaxing evening.

Head back to your accommodation in Prague and get some rest in preparation for another magical day of your road trip in the Czech Republic!

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Day 3

Day 3

  • Prague
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Drive 76 km, 1 hour 57 min

  • Karlštejn Castle
  • St. Vitus Cathedral
  • Prague Castle
  • Dancing House
  • Powder Tower
  • Malá Strana
  • More

At the end of the day, you'll drive back to Prague, where you'll stay for 1 night more.

Make sure to visit Malá Strana, a popular neighborhood in Karlštejn. Spend some time wandering around the area and soak in its distinctive charm. You’ll also discover that several of the city’s must-see attractions are just around the corner.

Savor the day by visiting some of the best places to see in Prague, including a castle, a church, an art installation, a monument and much more! Start your adventure at Karlštejn Castle. This interesting castle is a must-visit for travelers looking for a unique holiday experience. Make your way to St. Vitus Cathedral located in Prague for another exciting encounter.

Next, immerse yourself in the setting of Prague Castle. Its culturally significant features will captivate you. After the castle, continue your tour of the village with a visit to Dancing House. Visitors usually appreciate the visually striking features of this art installation. Next up is Powder Tower, a highly recommended monument.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Prague.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Prague. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Don’t miss out on dining at Brasileiro Restaurant, a top-rated dining destination in Prague. If you're in the mood to try something new, consider Restaurant Meat Beer, another top spot with a mouthwatering menu. You might also want to secure a reservation at Restaurace Století. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Prague this evening.

Explore the vibrant nightlife at Bowla Bar after your meal, a hub for lively evenings and memorable moments. Or, head to The Saints for a great selection of flavorful drinks and a charming setting. Furthermore, Beergeek Bar is perfect for those looking to extend their night with a touch of local flavor.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in the Czech Republic.

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Day 4

Day 4

  • Prague
  • Brno
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Drive 285 km, 3 hours 55 min

  • Zámecká Zahrada
  • Telč château
  • Zacharias of Hradec Square
  • Telč House
  • Rozhledna Oslednice
  • More

Dive into day 4 of your remarkable road trip in the Czech Republic. Today you will explore Telč, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Brno. You’ll stay here for 1 night.

Set out on a day brimming with fun adventures, romantic experiences, and breathtaking views. Start at the intriguing Castle Garden, a romantic castle in Prague. Next, go to Telč Château.

After visiting Castle Garden and Telč Château, have a stroll along Prague's streets and take in the local charm. Continue your sightseeing by heading to Zacharias Of Hradec Square. This romantic public square offers a unique experience. Telč is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Observation Tower Oslednice, one of the most romantic places to visit in Prague.

At the end of the day, you will drive to Brno, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Brno's best restaurants.

Make sure to reserve a table at Nok Nok Restaurace Brno, an iconic dining spot in Brno. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Sportovní areál Komec, a popular restaurant in Brno. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Restaurace L'Eau Vive, a hidden gem nestled in Brno. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Round off your dining experience by visiting Jazzový Bar U Kouřícího Králíka, a prime location for a drink. Alternatively, explore the distinctive characteristics of Queen Luxury Hookah Club, a bar catering to every mood and preference. Shot Bar likewise offers a unique atmosphere, perfect for a memorable night out.

Relax and recharge in preparation for another adventurous day in the Czech Republic!

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Day 5

Day 5

  • Brno - Departure day
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  • Masarykova Street
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Day 5 of your road trip in the Czech Republic is your departure day. This is your chance to catch a last glimpse of Brno before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

One of the best things to do on your last day is to explore Masarykova Street, a street that captures the true essence of Brno. Take your time to uncover its best sides and enjoy its proximity to many of the area’s best attractions.

Maximize your last day in the Czech Republic and go on a shopping spree in Brno’s shopping center, the lively Galerie Vaňkovka. Browse for souvenirs to remind you of your wonderful journey in the Czech Republic.

Before you conclude your road trip in the Czech Republic, drop by another restaurant for a last chance at a memorable dining experience in Brno.

You’ll then say farewell to Brno. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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