5-Day the Czech Republic Self-Drive Road Trip With Itinerary from Prague to Český Krumlov

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Photo of famous Charles Bridge over the Vltava river in Prague, Czech Republic.
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Experience the freedom of the open road on an unforgettable 5-day road trip in the Czech Republic! Embark on a self-drive tour that caters to every traveler, featuring destinations like Prague, Český Krumlov, Carlsbad, and Loket.

This perfectly planned road trip itinerary takes you through some of the best places to see in the Czech Republic. You will spend 3 nights in Prague and 1 night in Český Krumlov. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Prague, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Prague Castle and Charles Bridge are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Old Town Square, learn more about the unique St. Vitus Cathedral, and immerse yourself in the vibrant atmosphere of Prague Astronomical Clock.

As you hit the open road and drive through Prague, Český Krumlov, Carlsbad, and Loket, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
Drop-off: 10:00

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Day 1

Day 1

  • Prague - Arrival day
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  • Malá Strana
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Say hello to Prague! Your exciting road trip through the Czech Republic is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Prague for 2 nights before you continue your adventure!

Prague is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Prague. Check-in typically starts around 2 to 4 PM at hotels in the Czech Republic. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at U Tellerů, a highly-rated dining destination in Prague. If you're eager to try something different, consider Restaurace U Bansethů, another top spot with a tantalizing menu. You might also want to secure a reservation at Eska Restaurant and Bakery. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Prague this evening.

After enjoying a fulfilling meal, continue your evening at Anonymous Shrink's Office, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Bar No. 7 - Prague offers a welcoming atmosphere for easing into the nightlife. Similarly, Kontakt Bar provides an excellent environment for a relaxed and enjoyable evening.

Raise a toast to the start of your 5-day road trip in the Czech Republic!

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Day 2

Day 2

  • Prague
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Drive 5 km, 42 min

  • Old Town Square
  • Prague Astronomical Clock
  • Charles Bridge
  • St. Vitus Cathedral
  • Prague Castle
  • Staré Město
  • More

Day 2 of your road trip will take you to the best attractions Prague has to offer. Cherish the 1 night you have left in the city and use the provided itinerary to discover what to see in Prague.

One of the most iconic spots you can visit today is Staré Město. Allow yourself some time to explore this neighborhood and discover its unique quirks. You'll also find many of the best sightseeing spots nearby.

Look forward to a unique sightseeing adventure at the iconic Old Town Square and allow yourself time to explore. Just a short distance away you'll find your next stop, Prague Astronomical Clock, a grand historical landmark that draws visitors from far and near.

Continue your journey to Charles Bridge, one of the city’s most iconic spots that you shouldn’t miss. Another great site to visit is the astonishing St. Vitus Cathedral. When you're finished at the church, Prague Castle awaits your visit. This castle is an inviting highlight on today's itinerary.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Prague's best restaurants.

Enjoy a delicious meal at Brasileiro Restaurant, a highly-rated dining destination in Prague. If you're eager to try something different, consider Restaurant Meat Beer, another top spot with a tantalizing menu. You might also want to secure a reservation at Restaurace Století. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Prague this evening.

After savoring a delicious meal, step into the vibrant nightlife at Bowla Bar, where the evening is just getting started. In the same way, The Saints offers a unique charm perfect for experiencing the local bar scene in Prague. Beergeek Bar is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in the Czech Republic.

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Day 3

Day 3

  • Prague
  • Český Krumlov
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Drive 179 km, 2 hours 44 min

  • The Castle Garden
  • Český Krumlov Castle Tower
  • Monastery of the Minorites
  • Regional Museum in the Czech Krumlov
  • Egon Schiele Art Centrum
  • More

Your itinerary for day 3 of your road trip in the Czech Republic includes 1 stop and features some of the highlights of Český Krumlov. At the end of the day, enjoy the comforts of a top-rated hotel in Český Krumlov, where you'll spend 1 night.

Enjoy all that The Castle Garden has to offer. This is an often recommended castle you should not miss. Another must-see is Český Krumlov Castle Tower, a curiosity-inducing castle in Prague.

When you’re ready for the next sight, head to Monastery Of The Minorites. From there, take a leisurely stroll to Regional Museum In The Czech Krumlov, another of the town’s worthwhile attractions. We recommend continuing your self-guided tour at Egon Schiele Art Centrum, a visually striking place of interest in the town.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Český Krumlov. Český Krumlov offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Český Krumlov is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Český Krumlov.

Raise your glass and celebrate another amazing day of your road trip in the Czech Republic!

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Day 4

Day 4

  • Český Krumlov
  • Prague
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Drive 464 km, 6 hours 3 min

  • Park Colonnade
  • Market Colonnade
  • Diana Observation Tower
  • Loket Castle
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Dive into day 4 of your remarkable road trip in the Czech Republic. Today you'll explore 2 destinations, including Carlsbad and Loket. At the end of the day, you’ll unwind at one of the finest accommodations in Prague, where you'll spend 1 night.

One of the most locally appreciated attractions included on the itinerary is Park Colonnade. This romantic monument will help you start your sightseeing on top. Then, take a leisurely stroll to Market Colonnade and learn what makes this majestic monument unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the captivating Rozhledna Diana. After exploring the observation deck, head to Loket Castle. This locally renowned castle is a highlight in Český Krumlov.

When you’re done exploring for the day, you’ll drive to your hotel in Prague. Check in and relax before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at BeBop Bar, an excellent option for tonight's dining. Looking for something different? Café restaurant Palanda offers a tantalizing alternative with its diverse menu. And don’t miss Restaurace Tiskárna. Known for great service, it’s a fantastic choice for tonight in Prague.

Round off your dining experience by visiting Uhříněveský Bar, a prime location for a drink. Alternatively, explore the distinctive characteristics of Boothill Bar, a bar catering to every mood and preference. Manesova Bar And Books likewise offers a unique atmosphere, perfect for a memorable night out.

Savor another day of unforgettable experiences in the Czech Republic!

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Day 5

Day 5

  • Prague - Departure day
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  • Vyšehrad
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Day 5 of your road trip in the Czech Republic is your departure day. This is your chance to catch a last glimpse of Prague before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Vyšehrad, an inviting castle before you head out.

Take advantage of your accommodation's proximity to Prague’s shopping district for some last-minute bargain hunting. Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in the Czech Republic, drop by another restaurant for a last chance at a memorable dining experience in Prague.

You’ll then say farewell to Prague. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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