5-Day the Czech Republic Self-Drive Road Trip With Itinerary from Prague to Plzeň and surrounding area

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Photo of famous Charles Bridge over the Vltava river in Prague, Czech Republic.
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Description

Experience the freedom of the open road on an unforgettable 5-day road trip in the Czech Republic! Embark on a self-drive tour that caters to every traveler, featuring destinations like Prague, Plzeň, and Karlštejn.

This perfectly planned road trip itinerary takes you through some of the best places to see in the Czech Republic. You will spend 3 nights in Prague and 1 night in Plzeň. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Prague, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Prague Castle and Charles Bridge are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Old Town Square, learn more about the unique St. Vitus Cathedral, and immerse yourself in the vibrant atmosphere of Prague Astronomical Clock.

As you hit the open road and drive through Prague, Plzeň, and Karlštejn, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
Drop-off: 10:00

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Day 1

Day 1

  • Prague - Arrival day
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  • Franz Kafka - Rotating Head
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Your road trip adventure in the Czech Republic begins as soon as you reach Prague and pick up your car. You’ll stay here for 2 nights and explore what to see in Prague, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Prague is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Franz Kafka - Rotating Head By David Cerny, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Prague. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at U Tellerů, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Restaurace U Bansethů offers an enticing alternative with its varied menu. Additionally, Eska Restaurant and Bakery is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Prague.

Cap off your dinner by heading to Anonymous Shrink's Office, ideal for a leisurely evening with a drink in hand. Bar No. 7 - Prague is another bar that offers an enjoyable setting. Similarly, Kontakt Bar is also a popular place to go on a night out, perfect for relaxing and socializing.

Raise a toast to the start of your 5-day road trip in the Czech Republic!

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Day 2

Day 2

  • Prague
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Drive 15 km, 46 min

  • Vyšehrad
  • Dancing House
  • St. Vitus Cathedral
  • Prague Castle
  • Malá Strana
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Day 2 offers an itinerary packed with the best things to see in Prague. You’ll stay in Prague for 1 night more, offering you enough time to explore at a relaxed pace.

Prague is brimming with adventures. Malá Strana is a neighborhood that stands out as one of the must-see places in Prague. Take a moment to explore its distinct atmosphere, and don’t miss the popular sightseeing spots just a short walk away.

Let Vyšehrad set the tone for the day. Spend some time admiring this romantic castle before continuing your journey. Dancing House is your next stop. This astonishing art installation is one of the best-rated sights in Prague.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit St. Vitus Cathedral. This history-steeped church is a sight to behold. To round off your sightseeing experience, visit Prague Castle.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

Prague is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Prague.

Savor the flavors at Brasileiro Restaurant, a top pick for dinner tonight. Alternatively, Restaurant Meat Beer beckons with its unique menu offerings. Also, consider Restaurace Století. With its consistent customer satisfaction, it’s an excellent option for dining in Prague tonight.

Keep the evening going at Bowla Bar, a great choice for enjoying the after-dinner hours with a drink. You could also go to The Saints, which offers a similarly pleasant setting and great drinks. Another option is Beergeek Bar, which provides an inviting environment for unwinding after a busy day out.

Celebrate another amazing day of your road trip adventure in the Czech Republic!

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Day 3

Day 3

  • Prague
  • Plzeň-City District
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Drive 103 km, 1 hour 34 min

  • Old Town Square
  • Prague Astronomical Clock
  • Prague Zoo
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On day 3 of your exciting self-drive vacation in the Czech Republic, you’ll soak in the magnificence of 1 destination, including Prague. When you’re not sightseeing, take time to relax at your chosen hotel in Plzeň, where you’ll be staying for 1 night.

Whatever your travel style is, Old Town Square is an essential stop in Prague. This iconic public square provides an insightful glimpse into the city's identity. Next, discover Prague Astronomical Clock, a grand historical landmark, promising a delightful encounter.

Continue your sightseeing with a visit to Prague Zoo, a top-rated zoo.

At the end of the day, you will drive to Plzeň, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Plzeň is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Plzeň.

Treat yourself to a wonderful meal at Raven Pub City, a top-rated dining spot in Plzeň. If you're in the mood for something new, try Restaurace & Hotel U Salzmannů, another premier location with a delectable menu. You might also want to book a table at Pláž OSTENDE BOLEVÁK. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Plzeň.

After your meal, keep the night alive at a bar like Francis - Beer Café, known for its lively atmosphere. My Friends Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Beer Bar Pioneer offers an excellent atmosphere for those looking to amp up the evening.

As the sun sets, rest up and recharge for the next leg of your road trip in the Czech Republic.

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Day 4

Day 4

  • Plzeň-City District
  • Prague
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Drive 117 km, 1 hour 58 min

  • Cathedral of St. Bartholomew
  • Plzeň Zoo
  • Karlštejn Castle
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Your itinerary for day 4 of your road trip in the Czech Republic includes 2 stops and features some of the highlights of Plzeň and Karlštejn. At the end of the day, enjoy the comforts of a top-rated hotel in Prague, where you'll spend 1 night.

Awaiting your discovery is the worthwhile Cathedral Of St. Bartholomew, a majestic church in Plzeň. Next, go to Dinopark Plzeň.

After visiting Cathedral Of St. Bartholomew and Dinopark Plzeň, have a stroll along Plzeň's streets and take in the local charm. Continue your sightseeing by heading to Karlštejn Castle. This visually striking castle offers a unique experience.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Prague. Prague offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Prague's best restaurants.

Treat yourself to a delightful dinner at BeBop Bar, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Café restaurant Palanda? It's another excellent option with a diverse menu. Consider reserving a table at Restaurace Tiskárna as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Prague.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Uhříněveský Bar stands out as an excellent choice for a post-dinner cocktail. Alternatively, Boothill Bar offers an ideal atmosphere to enjoy the pleasures of the night. Manesova Bar And Books is also a great option that provides a perfect setting for a relaxing evening.

Raise your glass to another unforgettable day in the Czech Republic!

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Day 5

Day 5

  • Prague - Departure day
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  • Charles Bridge
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Day 5 of your road trip in the Czech Republic is your departure day. This is your chance to catch a last glimpse of Prague before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Charles Bridge. This timeless historical landmark is a hotspot among locals.

Take advantage of your accommodation's proximity to Prague’s shopping district for some last-minute bargain hunting. Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in the Czech Republic, drop by another restaurant for a last chance at a memorable dining experience in Prague.

If you're in the mood to try something new, consider U Fleků, another top spot with a mouthwatering menu.

You’ll then say farewell to Prague. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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