5-Day the Czech Republic Self-Drive Road Trip With Itinerary from Prague to Plzeň and surrounding area

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Photo of famous Charles Bridge over the Vltava river in Prague, Czech Republic.
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Description

Explore the best of the Czech Republic on a remarkable 5-day road trip! Combine exploration with relaxation on a self-drive tour featuring Prague, Plzeň, and Karlštejn.

This perfectly planned road trip itinerary takes you through some of the best places to see in the Czech Republic. You will spend 3 nights in Prague and 1 night in Plzeň. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Prague, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Prague Castle and Charles Bridge are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Prague, Plzeň, and Karlštejn, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
Drop-off: 10:00

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Day1

Day 1

  • Prague - Arrival day
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  • Franz Kafka - Rotating Head
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Your road trip adventure in the Czech Republic begins as soon as you reach Prague and pick up your car. You’ll stay here for 2 nights and explore what to see in Prague, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Prague is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Franz Kafka - Rotating Head By David Cerny. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Prague. Check-in typically starts around 2 to 4 PM at hotels in the Czech Republic. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at U Tellerů, a popular restaurant in Prague. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Prague at Restaurace U Bansethů, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Eska Restaurant and Bakery. It’s yet another ideal choice to enhance your time in Prague tonight.

Continue your evening by exploring the vibrant nightlife scene at Anonymous Shrink's Office, a prime destination for a thrilling night out. Also, don’t forget to check out Bar No. 7 - Prague, a bar that offers unique local touches. Likewise, Kontakt Bar provides an excellent alternative for a fun evening.

Raise a toast to the start of your 5-day road trip in the Czech Republic!

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Day2

Day 2

  • Prague
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Drive 15 km, 46 min

  • Vyšehrad
  • Dancing House
  • St. Vitus Cathedral
  • Prague Castle
  • Malá Strana
  • More

Day 2 of your road trip across the Czech Republic promises a magnificent time exploring what to see in Prague. You have 1 night left in Prague. Take the opportunity to experience more of the best attractions and activities in the city.

Prague is brimming with adventures. Malá Strana is a neighborhood that stands out as one of the must-see places in Prague. Take a moment to explore its distinct atmosphere, and don’t miss the popular sightseeing spots just a short walk away.

Your adventure in Prague is only getting started when you visit Vyšehrad, a notable local hot spot. Another notable attraction to explore is Dancing House. This widely recognized art installation is known for its history-steeped appeal.

After soaking in the highlights of these sights, take some time to wander Prague's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to St. Vitus Cathedral. This grand church offers a fascinating experience that many visitors find memorable. Prague Castle is also worth visiting.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

For an unforgettable shopping experience, visit Na Příkopě Street, the top shopping destination in Prague. Browse local shops and stores, each offering delightful surprises. Find unique souvenirs or items to take home. After shopping, explore what Na Příkopě Street has to offer, including attractions, essential services, and vibrant community activities.

Indulge in a memorable dining experience at one of Prague's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy a delicious meal at Brasileiro Restaurant, a highly-rated dining destination in Prague. If you're eager to try something different, consider Restaurant Meat Beer, another top spot with a tantalizing menu. You might also want to secure a reservation at Restaurace Století. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Prague this evening.

Unwind after your meal by stepping into Bowla Bar. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, The Saints offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Beergeek Bar, another top-rated bar in the area.

Relax and look forward to more memorable moments to come!

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Day3

Day 3

  • Prague
  • Plzeň-City District
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Drive 103 km, 1 hour 34 min

  • Old Town Square
  • Prague Astronomical Clock
  • Prague Zoo
  • More

Your itinerary for day 3 of your road trip in the Czech Republic includes 1 stop and features some of the highlights of Prague. At the end of the day, enjoy the comforts of a top-rated hotel in Plzeň, where you'll spend 1 night.

Experience Old Town Square, a globally renowned public square in the city. Then, head to Prague Astronomical Clock and soak in the ambiance of this enchanting historical landmark.

There are many interesting places to see in Prague, and when you are ready for more, go to Prague Zoo. This is one of the city’s most spectacular stunning spots of interest.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Plzeň. Plzeň offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Plzeň, it's often a good idea to reserve a table in advance.

Savor the flavors at Raven Pub City, a top pick for dinner tonight. Alternatively, Restaurace & Hotel U Salzmannů beckons with its unique menu offerings. Also, consider Pláž OSTENDE BOLEVÁK. With its consistent customer satisfaction, it’s an excellent option for dining in Plzeň tonight.

Continue your evening by exploring the vibrant nightlife scene at Francis - Beer Café, a prime destination for a thrilling night out. Also, don’t forget to check out My Friends Bar, a bar that offers unique local touches. Likewise, Beer Bar Pioneer provides an excellent alternative for a fun evening.

Celebrate another amazing day of your road trip adventure in the Czech Republic!

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Day4

Day 4

  • Plzeň-City District
  • Karlštejn
  • Prague
  • More

Drive 117 km, 1 hour 58 min

  • Cathedral of St. Bartholomew
  • Plzeň Zoo
  • Karlštejn Castle
  • More

On day 4 of your road trip in the Czech Republic, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Plzeň and Karlštejn are on today's agenda. In the evening, you’ll end up in Prague, where you will stay for 1 night.

Cathedral Of St. Bartholomew is must-visit church and a great option for a daytime tour of the area. Continue your journey to Dinopark Plzeň, a captivating zoo, located just a leisurely stroll away.

After soaking in Plzeň’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Karlštejn. Expect your car journey to take a minimum of 1 hour 5 min. When you arrive in Karlštejn, it's time to take a break from the road.

Spend your afternoon discovering Karlštejn Castle, a locally renowned castle known for its visually striking features.

When you’re done exploring for the day, you’ll drive to your hotel in Prague. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Prague's best restaurants.

Make sure to reserve a table at BeBop Bar, an iconic dining spot in Prague. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Café restaurant Palanda, a popular restaurant in Prague. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Restaurace Tiskárna, a hidden gem nestled in Prague. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Following your dinner, dive into the local bar culture at Uhříněveský Bar. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Boothill Bar, the perfect place for those looking to experience the best of the nightlife. Similarly, Manesova Bar And Books provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Raise your glass and celebrate another amazing day of your road trip in the Czech Republic!

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Day5

Day 5

  • Prague - Departure day
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  • Charles Bridge
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Day 5 of your road trip in the Czech Republic is your departure day. This is your chance to catch a last glimpse of Prague before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Charles Bridge, a culturally significant historical landmark before you head out.

For a last-minute shopping spree in Prague, Na Příkopě Street is nearby. Enjoy a variety of retail stores, dining options, and essential services in one convenient location.

Before you conclude your road trip in the Czech Republic, drop by another restaurant for a last chance at a memorable dining experience in Prague.

If you're in the mood to try something new, consider U Fleků, another top spot with a mouthwatering menu.

You’ll then say farewell to Prague. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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