6-Day the Czech Republic Self-Drive Road Trip With Itinerary from Prague traveling east to Český Krumlov and Brno

On day 2 of your road trip in the Czech Republic, you’ll start and end your day in Prague, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Prague, there’s no need to rush. Experience Prague and Kutná Hora to the fullest today with this curated day itinerary.

Don’t miss Malá Strana today, a must-see neighborhood that offers a glimpse into the city’s vibrant character. Take your time to explore its best features, and enjoy the convenience of nearby top-rated landmarks.

Check out the iconic castle, Prague Castle. Afterward, continue to Powder Tower, a monument every traveler should visit. As you explore Prague’s charming streets, take in the lively atmosphere and get to know the character of the city.

Next, make your way to Sedlec Ossuary. This interesting church is an essential stop. Following that, head to St Barbara's Cathedral, another must-visit site that will enhance your experience.

When you’re done exploring for the day, you’ll return to Prague and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Prague. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a wonderful meal at Brasileiro Restaurant, a top-rated dining spot in Prague. If you're in the mood for something new, try Restaurant Meat Beer, another premier location with a delectable menu. You might also want to book a table at Restaurace Století. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Prague.

Keep the evening going at Bowla Bar, a great choice for enjoying the after-dinner hours with a drink. You could also go to The Saints, which offers a similarly pleasant setting and great drinks. Another option is Beergeek Bar, which provides an inviting environment for unwinding after a busy day out.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in the Czech Republic.

On day 3 of your road trip in the Czech Republic, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Český Krumlov are on today's agenda. In the evening, you’ll end up in Český Krumlov, where you will stay for 1 night.

The Castle Garden is an ideal stop early in the day. This intriguing castle is a must-visit in the town. When you’re ready for your next discovery, continue to Český Krumlov Castle Tower, which may be one of the most history-steeped places you will experience today.

One of the best things about exploring Prague on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Lazebnický Most, an often recommended bridge in the town. If you’re up for more discoveries, don’t forget to reserve some time for House Of Mirrors and Egon Schiele Art Centrum. End your day with a visit to Moldavite Museum, a beloved museum that’s sure to leave a lasting impression.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Český Krumlov. Český Krumlov offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Český Krumlov. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Raise your glass to another unforgettable day in the Czech Republic!

On day 4 of your exciting self-drive vacation in the Czech Republic, you’ll soak in the magnificence of 2 destinations, including Telč and Brno. When you’re not sightseeing, take time to relax at your chosen hotel in Brno, where you’ll be staying for 1 night.

Visiting Telč Château is always a good idea. This often recommended castle is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the breathtaking wonders of Villa Tugendhat, a must-see museum in the town.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Cathedral Of St. Peter And Paul. This frequently visited church offers an enriching experience. For a change of pace, head to Špilberk Castle, where you can take in instagrammable features.

At the end of the day, you will drive to Brno, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brno, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at U Štíra, a popular restaurant in Brno. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Brno at Bistro Franz, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Noem Arch Restaurant. It’s yet another ideal choice to enhance your time in Brno tonight.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Bar Naproti stands out as an excellent choice for a post-dinner cocktail. Alternatively, Super Panda Circus offers an ideal atmosphere to enjoy the pleasures of the night. Výčep Na Stojáka is also a great option that provides a perfect setting for a relaxing evening.

As the sun sets, rest up and recharge for the next leg of your road trip in the Czech Republic.

Your itinerary for day 5 of your road trip in the Czech Republic includes 3 stops and features some of the highlights of Nové Dvory, Sloup, and Litomyšl. At the end of the day, enjoy the comforts of a top-rated hotel in Prague, where you'll spend 1 night.

To truly experience Brno, make sure to drop by Macocha Abyss. This increasingly popular cave is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Punkva Caves, one of the village’s best highlights.

Next, check out Sloupsko-šošůvské Jeskyně, one of the most locally appreciated places to see in Brno. This cave system is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Monastery Gardens In Litomyšl. Wander around and soak in the visually striking atmosphere this monastery offers.

When you’re done exploring for the day, you’ll drive to your hotel in Prague. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Prague. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a delightful dinner at BeBop Bar, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Café restaurant Palanda? It's another excellent option with a diverse menu. Consider reserving a table at Restaurace Tiskárna as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Prague.

Keep the evening going at Uhříněveský Bar, a great choice for enjoying the after-dinner hours with a drink. You could also go to Boothill Bar, which offers a similarly pleasant setting and great drinks. Another option is Manesova Bar And Books, which provides an inviting environment for unwinding after a busy day out.

Raise your glass and celebrate another amazing day of your road trip in the Czech Republic!