7-Day Czech Republic Road Trip from Prague traveling south to Plzeň, Ceske Budejovice, and Brno

Your road trip adventure in the Czech Republic begins as soon as you reach Prague and pick up your car. You’ll stay in Prague for 2 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Prague is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Powder Tower or taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Prague. Check-in typically starts around 2 to 4 PM at hotels in Czech Republic. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat in Prague. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

This renowned restaurant holds , and offers an exceptional menu of cuisine. Make sure to reserve a table at U Tellerů, an iconic dining spot in Prague. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Brasileiro Restaurant, a popular restaurant in Prague. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of OSSEGG Praha - Pivovar & Restaurace, a hidden gem nestled in Prague. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

If you’re not ready to end the night just yet, BeerGeek Bar offers a perfect venue to relax and savor a drink. Similarly, Hemingway Bar is well-suited for those looking to unwind in a social setting. Anonymous Bar is another excellent spot to enjoy a nightcap after a delightful meal.

Raise a toast to the start of your 7-day road trip in the Czech Republic!

Day 2 of your road trip across Czech Republic promises a magnificent time exploring Prague. You have 1 night left in Prague. Take the opportunity to experience more of the best attractions and activities in the city.

Begin your sightseeing with a visit to Vyšehrad. This fortress gets 45,878 visitors each year and is rated an average of 4.8 out of 5 stars in 45,689 reviews.

Next up, make your way to Národní Muzeum (National Museum, Prague). This national museum has an average rating of 4.5 out of 5 stars from 34,095 reviews.

When you’re ready for your next sight of the day, continue to Letná Park. This park has an average rating of 4.7 out of 5 stars from 25,680 visitors.

Beyond the above-mentioned attractions, you also have the opportunity to visit St. Vitus Cathedral. This catholic cathedral is rated an average of 4.8 out of 5 stars by 80,048 visitors.

If you’re keen to explore even more, then consider a visit to Prague Castle. This castle is a much-appreciated attraction with an average rating of 4.7 out of 5 stars from 167,293 visitors. Approximately 512,800 travelers visit Prague Castle every year.

There are plenty of experiences you can choose from in the Czech Republic that will add excitement to your vacation. When you’re keen to discover what else Prague has in store for you, use this day to go on a tour. This tour allows curious travelers like you to experience the best of the country. You can make the most of your time in the Czech Republic by scrolling down and selecting tours and activities to include on your itinerary for the day.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Prague.

Have a fantastic dining experience at The Grand Mark Prague, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Lokál offers an enticing alternative with its varied menu. Additionally, Gastro Bar 1401 Praha is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Prague.

Extend your evening after a delightful meal by visiting Black Angel's Bar, which offers the perfect atmosphere for a night out. Moreover, DÉJÁVU Music Club Prague is another popular option for a drink or two. Likewise, NIGHTMARE Prague Horror Bar also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Raise your glass and celebrate another amazing day of your road trip in Czech Republic!

On day 3 of your road trip in Czech Republic, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Prague. In the evening, you’ll end up in Plzeň, where you will stay for 1 night.

When you’ve had your share of Prague, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Plzeň. Your travel time is around 1 hour 15 min.

Begin your sightseeing with a visit to Old Town Square. This extraordinary square is rated an average of 4.8 out of 5 stars by 103,139 visitors.

Next, make your way to Prague Astronomical Clock. This top attraction is an astronomical clock with an average rating of 4.7 out of 5 stars by 61,492 visitors.

We also recommend a visit to Franz Kafka - Rotating Head by David Cerny. This sightseeing destination is rated 4.5 out of 5 stars by 25,527 travelers.

If you’re keen to keep exploring, visit Dancing House. This highly recommended sightseeing destination has received an average rating of 4.3 out of 5 stars from 53,539 travelers.

Today is also your chance to spend some time at Prague Zoo. This zoo is rated an average of 4.8 out of 5 stars by 56,551 travelers. It’s estimated that 1,445,126 people visit this fantastic attraction every year.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of Plzeň. Plzeň offers plenty of top-rated hotels and other places to stay on any travel budget. Check in at the hotel of your choice and take some time to relax before you head out to explore.

As you explore more of Plzeň, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Dine in style at Raven Pub City, a top recommendation for dinner tonight. Or, for a change of pace, Restaurace & Hotel U Salzmannů boasts a menu that's sure to impress. Also, be sure to check out Parkan. Known as a local hotspot, it’s a great choice for tonight in Plzeň.

After your meal, keep the night alive at a bar like Francis - Beer Café, known for its lively atmosphere. My Friends Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Cafe la Rose, Ltd. Offers an excellent atmosphere for those looking to amp up the evening.

Raise your glass to another unforgettable day in the Czech Republic!

Embark on another extraordinary experience on day 4 of your road trip in Czech Republic. Today, you will make 2 stops and experience some of the highlights of Plzeň and Český Krumlov. At the end of the day, you will enjoy the comforts of a top-rated hotel in Ceske Budejovice, which will be your home away from home for 1 night.

Continue your road trip and head to your next destination, Český Krumlov. This car ride takes around 2 hours 24 min.

When you're ready to see some sights, DinoPark Plzeň is a great place to start. This dinosaur park is rated an average of 4.7 out of 5 stars by 16,815 visitors.

Another popular attraction you can visit today is Pilsner Urquell Brewery. This sightseeing destination has an average rating of 4.7 out of 5 stars from 9,230 travelers.

When you’re ready to jump back into the car and say goodbye to Plzeň, you’ll hit the road in the direction of Český Krumlov. This drive usually takes around 2 hours 24 min. When you arrive, enjoy some sightseeing.

Take the opportunity to see Český Krumlov Castle. This attraction has an average rating of 4.8 out of 5 stars from 24,749 visitors and gets around 196,400 visits every year.

The Castle Garden is another sightseeing hotspot in the area. This park has been rated an average of 4.7 out of 5 stars by 5,448 travelers.

At the end of the day, you will drive to Ceske Budejovice, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Ceske Budejovice's most popular restaurants, and connect with friendly locals for an authentic adventure.

This renowned restaurant holds , and offers an exceptional menu of cuisine. Make sure to reserve a table at Potrefená husa IGY, České Budějovice, an iconic dining spot in Ceske Budejovice. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Paluba, a popular restaurant in Ceske Budejovice. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Alchymista, a hidden gem nestled in Ceske Budejovice. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your delicious meal, get a taste of the vibrant nightlife with a visit to The Dark, known for its inviting atmosphere. Cafe Hostel is another great option if you’re looking for a place to get the night started. Similarly, Singer Pub provides a great setting to enjoy the night away.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in the Czech Republic.

On day 5 of your exciting self-drive vacation in Czech Republic, you’ll soak in the magnificence of 3 destinations, Brno, Ceske Budejovice, and Hluboká nad Vltavou. When you’re not sightseeing, take time to relax at your selected hotel in Brno, where you’ll be staying for 1 night.

When you’re ready for some sightseeing, make your way to Špilberk Castle. This much-appreciated castle is rated 4.6 out of 5 stars in 14,289 reviews.

Next up is Špilberk Castle. This castle has an average rating of 4.7 out of 5 stars from 9,187 visitors.

Another top sightseeing recommendation is Náměstí Svobody. This sightseeing destination has been rated 4.6 out of 5 stars in 12,651 reviews.

Continue your road trip and head to your next destination, Hluboká nad Vltavou. This car ride takes around 17 min.

Begin your sightseeing with a visit to Samson fountain. This extraordinary park is rated an average of 4.7 out of 5 stars by 6,231 visitors.

When you’re done exploring for the day, you’ll drive to Brno, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Brno. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a delightful dinner at Bistro Franz, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Nok Nok Restaurace Brno? It's another excellent option with a diverse menu. Consider reserving a table at Borgo Agnese as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Brno.

Let the evening flow smoothly from dinner to drinks at Bar Naproti, a top-rated bar in the area. For other recommendations, Super Panda Circus provides a perfect setting for rounding out your night with style and great drinks. Likewise, Výčep Na Stojáka offers a memorable night with diverse drink options and excellent service.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in the Czech Republic.

Dive into day 6 of your remarkable road trip in Czech Republic. Today you will explore Lednice and Mikulov, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Prague. You’ll stay here for 1 night.

When you’re ready to jump back into the car and say goodbye to Mikulov, you’ll hit the road in the direction of Lednice. This drive usually takes around 17 min. When you arrive, enjoy some sightseeing.

Drop by the renowned Lednice Castle. This popular château has been rated an average of 4.8 out of 5 stars by 21,686 visitors. Based on recent data, this attraction is visited by more than 256,000 travelers every year.

Another unforgettable place to experience is Minaret. Rated 4.7 out of 5 stars by 5,867 visitors, this park deserves a spot on today's sightseeing itinerary.

We also recommend a visit to Lednice–Valtice Cultural Landscape. This park has been rated an average of 4.8 out of 5 stars in 24,450 reviews.

Mikulov’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Brno behind. This drive usually takes around 41 min. Mikulov welcomes you with a multitude of unique vacation experiences.

Begin your sightseeing with a visit to Kozí hrádek. This tower is rated an average of 4.6 out of 5 stars in 1,031 reviews.

Next up, make your way to Pálava Protected Landscape Area. This park has an average rating of 4.8 out of 5 stars from 11,934 reviews.

After soaking up all the sights of today's itinerary, you'll be ready to hit the road in the direction of Prague. Prague offers plenty of top-rated hotels and other places to stay on any travel budget. Check in at the hotel of your choice and take some time to relax before you head out to explore.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Prague.

Enjoy a delicious meal at Café Louvre, a highly-rated dining destination in Prague. If you're eager to try something different, consider U Pivrnce, another top spot with a tantalizing menu. You might also want to secure a reservation at V Zátiší. With a reputation for consistently satisfied customers, it’s an excellent choice to enhance your stay in Prague this evening.

Keep the evening going at Brothers Bar & Cafe, a great choice for enjoying the after-dinner hours with a drink.

Savor another day of unforgettable experiences in the Czech Republic!

Day 7 of your road trip in the Czech Republic is your departure day. This is your chance to catch a last glimpse of Prague before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Make the most of your final day in Czech Republic by visiting Prague’s iconic markets and shopping establishments. Your stay’s proximity to the city’s retail haven invites an unhurried and unforgettable exploration of its variety of stores and establishments. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Czech Republic. Take home a piece of Czech Republic with these souvenirs, keeping your adventures close.

Before you conclude your road trip in Czech Republic, drop by another restaurant for a last chance at a memorable dining experience in Prague.

Treat yourself to a delicious dinner at Restaurace Malostranská beseda, an excellent option for tonight's dining. Looking for something different? U Parlamentu offers a tantalizing alternative with its diverse menu. And don’t miss Café Jen.

You’ll then say farewell to Prague. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Czech Republic!