One-Week the Czech Republic Self-Drive Road Trip With Itinerary from Prague to Ústí Nad Labem and Špindlerův Mlýn and surrounding area

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Photo of famous Charles Bridge over the Vltava river in Prague, Czech Republic.
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Experience the freedom of the open road on an unforgettable 8-day road trip in the Czech Republic! Embark on a self-drive tour that caters to every traveler, featuring destinations like Prague, Plzeň, Karlštejn, Průhonice, Kutná Hora, Ústí Nad Labem, Mezná, Děčín, Vysoká Lípa, Harrachov, Špindlerův Mlýn, Janské Lázně, and Dvůr Králové nad Labem.

This perfectly planned road trip itinerary takes you through some of the best places to see in the Czech Republic. You will spend 5 nights in Prague, 1 night in Ústí Nad Labem, and 1 night in Špindlerův Mlýn. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Prague, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Prague Castle and Charles Bridge are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Prague, Plzeň, Karlštejn, Průhonice, Kutná Hora, Ústí Nad Labem, Mezná, Děčín, Vysoká Lípa, Harrachov, Špindlerův Mlýn, Janské Lázně, and Dvůr Králové nad Labem, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day1

Day 1

  • Prague - Arrival day
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  • Charles Bridge
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Welcome to Prague, the perfect starting point for your road trip in the Czech Republic! Pick up your rental car and let the adventure begin. You will spend 4 nights discovering what to see in Prague before embarking on the next leg of your journey.

Prague is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Charles Bridge. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Prague. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in the Czech Republic. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at U Tellerů, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Restaurace U Bansethů is another top choice with a popular menu. You could also check for a table at Eska Restaurant and Bakery. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Prague tonight.

Following your dinner, dive into the local bar culture at Anonymous Shrink's Office. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Bar No. 7 - Prague, the perfect place for those looking to experience the best of the nightlife. Similarly, Kontakt Bar provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Raise a toast to the start of your 8-day road trip in the Czech Republic!

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Day2

Day 2

  • Prague
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Drive 15 km, 1 hour 5 min

  • Prague Castle
  • St. Vitus Cathedral
  • Dancing House
  • Vyšehrad
  • National Museum in Prague
  • More

On day 2 of your road trip, you will have an entire day to discover what to see in Prague. You’ll stay in Prague for 3 nights.

Whatever your travel style is, Prague Castle is an essential stop in Prague. This world-famous castle provides an insightful glimpse into the city's identity. Next, discover St. Vitus Cathedral, an UNESCO world heritage-listed church, promising a delightful encounter.

Continue your sightseeing with a visit to Dancing House, a top-rated art installation. When you’re done, don’t forget to make a stop at the popular Vyšehrad. Round off your day at Národní Muzeum (national Museum, Prague), another gem in Prague with photogenic features to discover.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Prague. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a delicious meal at Brasileiro Restaurant, a highly-rated dining destination in Prague. If you're eager to try something different, consider Restaurant Meat Beer, another top spot with a tantalizing menu. You might also want to secure a reservation at Restaurace Století. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Prague this evening.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Bowla Bar stands out as an excellent choice for a post-dinner cocktail. Alternatively, The Saints offers an ideal atmosphere to enjoy the pleasures of the night. Beergeek Bar is also a great option that provides a perfect setting for a relaxing evening.

Relax and recharge in preparation for another adventurous day in the Czech Republic!

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Day3

Day 3

  • Prague
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Drive 27 km, 1 hour 4 min

  • Petrin Tower
  • Prague Astronomical Clock
  • Old Town Square
  • Powder Tower
  • Prague Zoo
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Day 3 offers an itinerary packed with the best things to see in Prague. You’ll stay in Prague for 2 nights more, offering you enough time to explore at a relaxed pace.

Look forward to a unique sightseeing adventure at the notable Petřín Lookout Tower and allow yourself time to explore. Just a short distance away you'll find your next stop, Prague Astronomical Clock, a grand historical landmark that draws visitors from far and near.

Continue your journey to Old Town Square, one of the city’s most timeless spots that you shouldn’t miss. Another great site to visit is the locally renowned Powder Tower. When you're finished at the monument, Prague Zoo awaits your visit. This zoo is a picture-perfect highlight on today's itinerary.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Prague's best restaurants.

Have a fantastic dining experience at BeBop Bar, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Café restaurant Palanda offers an enticing alternative with its varied menu. Additionally, Restaurace Tiskárna is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Prague.

To truly maximize your evening out, consider visiting Uhříněveský Bar after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Boothill Bar, another bar with an inviting ambiance. Similarly, Manesova Bar And Books also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Relax and look forward to more memorable moments to come!

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Day4

Day 4

  • Prague
  • Plzeň-City District
  • Karlštejn
  • More

Drive 212 km, 3 hours 23 min

  • Plzeň Zoo
  • Cathedral of St. Bartholomew
  • Pilsner Urquell Brewery
  • Karlštejn Castle
  • More

On day 4 of your road trip, you’ll start and end your day in Prague, where you have 1 night left to stay.

Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Plzeň.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Karlštejn may take around 1 hour 1 min. Upon your arrival in Karlštejn, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Our first attraction recommendation in Plzeň is Dinopark Plzeň, a notable zoo that draws attention for its gorgeous features. Spend some time soaking in the atmosphere before continuing to Cathedral Of St. Bartholomew, a stunning church that stands out in the city.

Time flies when you're having fun! But don't forget to stop for a bit to eat and drink between your adventures. When you're rested and recharged, head to Pilsner Urquell Brewery, an intriguing brewery that offers a unique experience.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Karlštejn may take around 1 hour 1 min. Upon your arrival in Karlštejn, you’ll be greeted with the opportunity to do some sightseeing and exploring.

For a more meaningful self-guided tour of the city's best attractions, visit Karlštejn Castle, a notable castle that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Prague.

Indulge in a memorable dining experience at one of Prague's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy a delicious meal at OSSEGG Praha - Pivovar & Restaurace, a top-rated dining destination in Prague. If you're in the mood to try something new, consider U Fleků, another top spot with a mouthwatering menu. You might also want to secure a reservation at Havelská Koruna. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Prague this evening.

Explore the vibrant nightlife at Bar Bohužel after your meal, a hub for lively evenings and memorable moments. Or, head to Hemingway Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Bar Tečka is perfect for those looking to extend their night with a touch of local flavor.

Raise your glass to another unforgettable day in the Czech Republic!

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Day5

Day 5

  • Prague
  • Průhonice
  • Kutná Hora
  • Ústí nad Labem
  • More

Drive 236 km, 3 hours 29 min

  • Park Průhonice
  • St Barbara's Cathedral
  • Italian Court
  • Sedlec Ossuary
  • More

Your itinerary for day 5 of your road trip in the Czech Republic includes 2 stops and features some of the highlights of Průhonice and Kutná Hora. At the end of the day, enjoy the comforts of a top-rated hotel in Ústí Nad Labem, where you'll spend 1 night.

Fasten your seatbelt and make your way to your next stop — Kutná Hora, home to many well-known sights in the region. Keep in mind that your travel time from Průhonice to Kutná Hora may take around 1 hour 5 min without traffic disruptions. Upon arrival in Kutná Hora, we highly recommend checking out some of the top attractions.

Spend your afternoon discovering Park Průhonice, a beloved botanical garden known for its serene features.

Set your GPS to Kutná Hora and hit the road. Expect a journey of approximately 1 hour 5 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Kutná Hora beckons with new experiences!

When you're ready for some sights, head to St Barbara's Cathedral, a locally renowned church in Kutná Hora. Explore its visually striking features at your own pace before you continue your journey to your next attraction, Italian Court. This beloved castle is a top recommendation in the area.

When you’re ready to explore more, Sedlec Ossuary is an excellent choice. Spend some time discovering what some claim to be the most respected church in the region.

When you’re done exploring for the day, you’ll drive to your hotel in Ústí Nad Labem. Check in and relax before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ústí Nad Labem, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Restaurant Větruše, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Hotel a Restaurant Větruše offers an enticing alternative with its varied menu. Additionally, BLACKSHEEP BAR is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Ústí Nad Labem.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Hp Bar, known for its inviting atmosphere. Ústecká Pivotéka is another great option if you’re looking for a place to get the night started. Similarly, Pubs Bar Hamburg provides a great setting to enjoy the night away.

Say good night to Ústí Nad Labem and look forward to another great day of your road trip in the Czech Republic!

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Day6

Day 6

  • Ústí nad Labem
  • Mezná
  • Děčín
  • Vysoká Lípa
  • Špindlerův Mlýn
  • More

Drive 217 km, 4 hours 16 min

  • Kamenice Gorge
  • Bohemian Switzerland National Park
  • Dolský Mlýn
  • More

Experience an unparalleled adventure on day 6 of your road trip in the Czech Republic. This exciting part of your journey invites you to discover the renowned landmarks in 4 places, which are Mezná, Děčín, Vysoká Lípa, and Harrachov. At the end of the day, you will retreat to the hotel of your choice in Špindlerův Mlýn, where will spend 1 night.

Continue your road trip and head to your next destination, Mezná. This car ride takes around 45 min.

Kamenice Gorge is an up-and-coming canyon we recommend visiting today. Discover its idyllic features before continuing your self-guided tour.

Fasten your seatbelt and make your way to your next stop — Děčín, home to many well-known sights in the region. Keep in mind that your travel time from Mezná to Děčín may take around 12 min without traffic disruptions. Upon arrival in Děčín, we highly recommend checking out some of the top attractions.

One of our top recommendations for your sightseeing is České Švýcarsko National Park. Spend some time admiring the serene features of the national park before you continue to your next stop.

Set your GPS to Vysoká Lípa and hit the road. Expect a journey of approximately 9 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Vysoká Lípa beckons with new experiences!

Our first attraction recommendation in Vysoká Lípa is Dolský Mlýn, an increasingly popular historical landmark that draws attention for its history-steeped features.

At the end of the day, you will drive to Špindlerův Mlýn, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Špindlerův Mlýn is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Špindlerův Mlýn.

Celebrate another amazing day of your road trip adventure in the Czech Republic!

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Day7

Day 7

  • Špindlerův Mlýn
  • Janské Lázně
  • Prague
  • More

Drive 232 km, 3 hours 28 min

  • Špindlerův Mlýn Ski Resort
  • The Timber Trail, Krkonoše
  • More

On day 7 of your road trip in the Czech Republic, your travel plans include 3 stops at the most scenic, wondrous, and interesting places in the region. Špindlerův Mlýn, Janské Lázně, and Dvůr Králové nad Labem are on today's agenda. In the evening, you’ll end up in Prague, where you will stay for 1 night.

Awaiting your discovery is the locally renowned Špindlerův Mlýn Ski Resort, a visually striking ski resort in Špindlerův Mlýn.

Continue your road trip and head to your next destination, Janské Lázně. This car ride takes around 35 min.

Savor the day by heading to The Timber Trail, Krkonoše, an interesting canopy walk that draws visitors from near and far.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Prague. Prague offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Prague. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a delicious meal at MAURIZIO restaurant & café, a top-rated dining destination in Prague. If you're in the mood to try something new, consider Gate Restaurant, another top spot with a mouthwatering menu. You might also want to secure a reservation at U Houmra. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Prague this evening.

Continue your evening by exploring the vibrant nightlife scene at Crazy Daisy, a prime destination for a thrilling night out. Also, don’t forget to check out Puerto Rico Cafe & Cocktail Bar, a bar that offers unique local touches. Likewise, Anonymous Bar provides an excellent alternative for a fun evening.

Get a good night's sleep and look forward to another great day on the road in the Czech Republic!

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Day8

Day 8

  • Prague - Departure day
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  • Letná Park
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Day 8 of your road trip in the Czech Republic is your departure day. This is your chance to catch a last glimpse of Prague before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Letná Park, an eye-catching park before you head out.

Make the most of your final day in the Czech Republic by visiting Prague’s iconic markets and shopping establishments in the buzzing Palladium. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation.

Before you conclude your road trip in the Czech Republic, drop by another restaurant for a last chance at a memorable dining experience in Prague.

If you're eager to try something different, consider The Grand Mark Prague, another top spot with a tantalizing menu.

You’ll then say farewell to Prague. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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