One-Week the Czech Republic Self-Drive Road Trip With Itinerary from Prague to Ústí Nad Labem and Špindlerův Mlýn and surrounding area

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Photo of famous Charles Bridge over the Vltava river in Prague, Czech Republic.
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Explore the best of the Czech Republic on a remarkable 8-day road trip! Combine exploration with relaxation on a self-drive tour featuring Prague, Plzeň, Karlštejn, Průhonice, Kutná Hora, Ústí Nad Labem, Mezná, Děčín, Vysoká Lípa, Harrachov, Špindlerův Mlýn, Janské Lázně, and Dvůr Králové nad Labem.

This perfectly planned road trip itinerary takes you through some of the best places to see in the Czech Republic. You will spend 5 nights in Prague, 1 night in Ústí Nad Labem, and 1 night in Špindlerův Mlýn. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Prague, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Prague Castle and Charles Bridge are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Old Town Square, learn more about the unique St. Vitus Cathedral, and immerse yourself in the vibrant atmosphere of Prague Astronomical Clock.

As you hit the open road and drive through Prague, Plzeň, Karlštejn, Průhonice, Kutná Hora, Ústí Nad Labem, Mezná, Děčín, Vysoká Lípa, Harrachov, Špindlerův Mlýn, Janské Lázně, and Dvůr Králové nad Labem, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day 1

Day 1

  • Prague - Arrival day
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  • Charles Bridge
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Your road trip adventure in the Czech Republic begins as soon as you reach Prague and pick up your car. You’ll stay here for 4 nights and explore what to see in Prague, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Prague is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Charles Bridge, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Prague. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at U Tellerů, an excellent option for tonight's dining. Looking for something different? Restaurace U Bansethů offers a tantalizing alternative with its diverse menu. And don’t miss Eska Restaurant and Bakery. Known for great service, it’s a fantastic choice for tonight in Prague.

Continue your lively evening at Anonymous Shrink's Office, a perfect place for winding down or revving up the night, depending on which mood you’re in. Bar No. 7 - Prague is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Kontakt Bar ensures a night out tailored to your taste.

Raise a toast to the start of your 8-day road trip in the Czech Republic!

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Day 2

Day 2

  • Prague
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Drive 15 km, 1 hour 5 min

  • Prague Castle
  • St. Vitus Cathedral
  • Dancing House
  • Vyšehrad
  • National Museum in Prague
  • More

On day 2 of your road trip, you will have an entire day to discover what to see in Prague. You’ll stay in Prague for 3 nights.

Your adventure in Prague is only getting started when you visit Prague Castle, a wondrous local hot spot. Another notable attraction to explore is St. Vitus Cathedral. This astonishing church is known for its UNESCO world heritage-designated appeal.

After soaking in the highlights of these sights, take some time to wander Prague's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Dancing House. This history-steeped art installation offers a fascinating experience that many visitors find memorable. Vyšehrad is also worth visiting, along with Národní Muzeum (national Museum, Prague). These standout landmarks offer unique experiences that add to the day’s enjoyment.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Prague. Enjoy a relaxing evening as you savor delicious local cuisine.

Have a fantastic dining experience at Brasileiro Restaurant, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Restaurant Meat Beer offers an enticing alternative with its varied menu. Additionally, Restaurace Století is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Prague.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Bowla Bar, a well-loved spot among locals and tourists. Or, head to The Saints. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Beergeek Bar, another top-rated place in the area.

Relax and look forward to more memorable moments to come!

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Day 3

Day 3

  • Prague
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Drive 27 km, 1 hour 4 min

  • Petrin Tower
  • Prague Astronomical Clock
  • Old Town Square
  • Powder Tower
  • Prague Zoo
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Day 3 of your road trip will take you to the best attractions Prague has to offer. Cherish the 2 nights you have left in the city and use the provided itinerary to discover what to see in Prague.

One of the most popular attractions included on the itinerary is Petřín Lookout Tower. This enchanting observation deck will help you start your sightseeing on top. Then, take a leisurely stroll to Prague Astronomical Clock and learn what makes this enchanting historical landmark unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the world-famous Old Town Square. After exploring the public square, head to Powder Tower. This interesting monument is a highlight in Prague. As your day continues, stop by Prague Zoo, known for its awe-inspiring features.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

Prague is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Prague.

Treat yourself to a wonderful meal at BeBop Bar, a top-rated dining spot in Prague. If you're in the mood for something new, try Café restaurant Palanda, another premier location with a delectable menu. You might also want to book a table at Restaurace Tiskárna. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Prague.

Round off your dining experience by visiting Uhříněveský Bar, a prime location for a drink. Alternatively, explore the distinctive characteristics of Boothill Bar, a bar catering to every mood and preference. Manesova Bar And Books likewise offers a unique atmosphere, perfect for a memorable night out.

As the sun sets, rest up and recharge for the next leg of your road trip in the Czech Republic.

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Day 4

Day 4

  • Prague
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Drive 212 km, 3 hours 23 min

  • Plzeň Zoo
  • Cathedral of St. Bartholomew
  • Pilsner Urquell Brewery
  • Karlštejn Castle
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Greet day 4 of your road trip in the Czech Republic with a smile and start your day with a hearty breakfast. You have 1 night to stay in Prague, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Plzeň and Karlštejn.

No visit to Prague is complete without Dinopark Plzeň. This locally renowned zoo is one of the top attractions in the city. Proceed to Cathedral Of St. Bartholomew, another must-visit attraction.

As you wander through the inviting streets of Prague, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Pilsner Urquell Brewery. This locally appreciated brewery is a traveler-favorite. Not far away, you’ll find Karlštejn Castle, another key site on your sightseeing itinerary.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Prague.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at OSSEGG Praha - Pivovar & Restaurace, a highly-rated dining destination in Prague. If you're eager to try something different, consider U Fleků, another top spot with a tantalizing menu. You might also want to secure a reservation at Havelská Koruna. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Prague this evening.

Explore the vibrant nightlife at Bar Bohužel after your meal, a hub for lively evenings and memorable moments. Or, head to Hemingway Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Bar Tečka is perfect for those looking to extend their night with a touch of local flavor.

Say good night to Prague and look forward to another great day of your road trip in the Czech Republic!

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Day 5

Day 5

  • Prague
  • Ústí nad Labem
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Drive 236 km, 3 hours 29 min

  • Park Průhonice
  • St Barbara's Cathedral
  • Italian Court
  • Sedlec Ossuary
  • More

Dive into day 5 of your remarkable road trip in the Czech Republic. Today you'll explore 2 destinations, including Průhonice and Kutná Hora. At the end of the day, you’ll unwind at one of the finest accommodations in Ústí Nad Labem, where you'll spend 1 night.

Look forward to a unique sightseeing adventure at the often recommended Park Průhonice and allow yourself time to explore. Just a short distance away you'll find your next stop, St Barbara's Cathedral, a majestic church that draws visitors from far and near.

Continue your journey to Italian Court, one of the village’s most increasingly popular spots that you shouldn’t miss. Another great site to visit is the locally renowned Sedlec Ossuary.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Ústí Nad Labem. Ústí Nad Labem offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Ústí Nad Labem is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Ústí Nad Labem.

Enjoy a lovely meal at Restaurant Větruše, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Hotel a Restaurant Větruše is another top choice with a popular menu. You could also check for a table at BLACKSHEEP BAR. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Ústí Nad Labem tonight.

Following your dinner, dive into the local bar culture at Hp Bar. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Ústecká Pivotéka, the perfect place for those looking to experience the best of the nightlife. Similarly, Pubs Bar Hamburg provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Head back to your accommodation in Ústí Nad Labem and get some rest to prepare for another magical day of your road trip in the Czech Republic.

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Day 6

Day 6

  • Ústí nad Labem
  • Špindlerův Mlýn
  • More

Drive 217 km, 4 hours 16 min

  • Kamenice Gorge
  • Bohemian Switzerland National Park
  • Dolský Mlýn
  • Mumlava Falls
  • More

Your itinerary for day 6 of your road trip in the Czech Republic includes 4 stops and features some of the highlights of Mezná, Děčín, Vysoká Lípa, and Harrachov. At the end of the day, enjoy the comforts of a top-rated hotel in Špindlerův Mlýn, where you'll spend 1 night.

Kamenice Gorge is must-visit canyon and a great option for a daytime tour of the area. Continue your journey to České Švýcarsko National Park, a notable national park, located just a leisurely stroll away. Next, head to Dolský Mlýn, a history-steeped historical landmark, also available for your discovery today.

At the end of the day, you will drive to Špindlerův Mlýn, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Špindlerův Mlýn, it's often a good idea to reserve a table in advance.

Known for great service, it’s a fantastic choice for tonight in Špindlerův Mlýn.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in the Czech Republic.

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Day 7

Day 7

  • Špindlerův Mlýn
  • Prague
  • More

Drive 232 km, 3 hours 28 min

  • Špindlerův Mlýn Ski Resort
  • Krkonoše National Park
  • The Timber Trail, Krkonoše
  • Dvůr Králové Zoo
  • More

Experience an unparalleled adventure on day 7 of your road trip in the Czech Republic. This exciting part of your journey invites you to discover the renowned landmarks in 3 places, which are Špindlerův Mlýn, Janské Lázně, and Dvůr Králové nad Labem. At the end of the day, you will retreat to the hotel of your choice in Prague, where will spend 1 night.

One of the most captivating attractions included on the itinerary is Špindlerův Mlýn Ski Resort. This instagrammable ski resort will help you start your sightseeing on top. Then, take a leisurely stroll to Krkonoše National Park and learn what makes this peaceful national park unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the interesting The Timber Trail, Krkonoše. After exploring the canopy walk, head to Dvůr Králové Zoo. This captivating zoo is a highlight in Špindlerův Mlýn.

When you’re done exploring for the day, you’ll drive to your hotel in Prague. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Prague's best restaurants.

Enjoy a lovely dining experience at MAURIZIO restaurant & café, a popular restaurant in Prague. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Prague at Gate Restaurant, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated U Houmra. It’s yet another ideal choice to enhance your time in Prague tonight.

After enjoying a fulfilling meal, continue your evening at Crazy Daisy, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Puerto Rico Cafe & Cocktail Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Anonymous Bar provides an excellent environment for a relaxed and enjoyable evening.

Relax and look forward to more memorable moments to come!

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Day 8

Day 8

  • Prague - Departure day
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  • Letná Park
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Day 8 of your road trip in the Czech Republic is your departure day. This is your chance to catch a last glimpse of Prague before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Letná Park, a romantic park before you head out.

Make the most of your final day in the Czech Republic by visiting Prague’s iconic markets and shopping establishments in the buzzing Wenceslas Square. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation.

Before you conclude your road trip in the Czech Republic, drop by another restaurant for a last chance at a memorable dining experience in Prague.

If you're eager to try something different, consider The Grand Mark Prague, another top spot with a tantalizing menu.

You’ll then say farewell to Prague. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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