One-Week the Czech Republic Road Trip from Prague to Ústí Nad Labem, and Špindlerův Mlýn and surrounding area

On day 2 of your road trip, you will have an entire day to explore Prague. You’ll stay in Prague for 3 nights and discover all the best things to see and do in the area.

Take the opportunity to see Prague Castle. This attraction has an average rating of 4.7 out of 5 stars from 168,149 visitors and gets around 512,800 visits every year.

St. Vitus Cathedral is another sightseeing hotspot in the area. This catholic cathedral has been rated an average of 4.8 out of 5 stars by 80,499 travelers.

Prague is also the home of Dancing House. Around 54,043 people have rated this office building an average of 4.3 out of 5 stars.

Another place you’ll want to visit is Vyšehrad, which hosts up to 45,878 visitors every year. With an average rating of 4.8 out of 5 stars from a total of 46,225 reviews, a visit to this fortress is a great idea.

This day of your vacation in Prague is also your chance to admire Národní Muzeum (national Museum, Prague). This must-visit national museum enjoys an average rating of 4.5 out of 5 stars from 34,864 reviews.

There are plenty of experiences you can choose from in the Czech Republic that will add excitement to your vacation. When you’re keen to discover what else Prague has in store for you, use this day to go on a tour. Scroll down and select tours and activities to include on your itinerary for the day.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Prague. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Set out on a gastronomic journey in Prague by reserving a table at Divinis. Renowned for its Bib Gourmand award, this restaurant presents an outstanding menu of italian cuisine. For a different taste, head over to Field, renowned for its delectable modern dishes. This distinguished 1-star Michelin-recipient is a favorite among guests, making it a worthy addition to your holiday plans. Craving more culinary excitement? Explore La Degustation Bohême Bourgeoise, a highly rated local gem known for its exquisite modern menu. With a 1-star Michelin acclaim, it promises a dining experience you won't want to miss. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Prague.

Continue the enjoyment post-dinner at Black Angel's Bar, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Déjávu Music Club Prague offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Nightmare Prague Horror Bar. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Relax and recharge in preparation for another adventurous day in the Czech Republic!

Day 3 offers a multitude of experiences. You will stay in Prague for 2 nights more, offering you enough time to explore at a relaxed pace.

An excellent attraction to start your day with is Petřín Lookout Tower. This observation tower typically receives around 234,200 visitors every year and is rated an average of 4.5 out of 5 stars in 29,077 reviews.

Continue your journey at Prague Astronomical Clock. This astronomical clock is rated 4.7 out of 5 stars by 62,538 travelers from near and far.

Prague is also the home of Old Town Square. This square has an average rating of 4.8 out of 5 stars from 103,679 visitors.

You can continue your self-guided sightseeing tour at Powder Tower. A total of 27,072 people explore this attraction every year. Rated 4.6 out of 5 stars by 41,605 visitors, a visit to this top sight is time well spent.

Lastly, don't miss out on Prague Zoo. With an average rating of 4.8 out of 5 stars from 57,548 reviews, it’s hard to refuse the opportunity to see this zoo. Approximately 1,445,126 people visit this attraction every year.

To immerse yourself in more memorable moments in Prague, check out the best-rated tours the region offers. You can discover and choose from all of the top-rated activities you can do on this day in Prague below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Prague. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Dine in style at Café Louvre, a top recommendation for dinner tonight. Or, for a change of pace, U Pivrnce boasts a menu that's sure to impress. Also, be sure to check out V Zátiší. Known as a local hotspot, it’s a great choice for tonight in Prague.

Extend your evening after a delightful meal by visiting Brothers Bar & Cafe, which offers the perfect atmosphere for a night out.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in the Czech Republic.

Wake up to day 4 of your extraordinary road trip in the Czech Republic. With 1 night left in Prague, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Karlštejn. This drive usually takes around 1 hour 1 min, without any stops or traffic disruptions.

Take the opportunity to see Dinopark Plzeň. This attraction has an average rating of 4.7 out of 5 stars from 17,031 visitors.

Cathedral Of St. Bartholomew is another sightseeing hotspot in the area. This catholic cathedral has been rated an average of 4.7 out of 5 stars by 6,897 travelers. Up to 50,412 people visit Cathedral Of St. Bartholomew every year.

Plzeň is also the home of Pilsner Urquell Brewery. Around 9,276 people have rated this point of interest an average of 4.7 out of 5 stars.

Fasten your seatbelt and make your way to your next stop. Karlštejn, home to many well-known sights in the region, is a lovely destination on today’s itinerary. Keep in mind that your travel time from Plzeň to Karlštejn may take around 1 hour 1 min without traffic disruptions. Upon arrival in Karlštejn, we highly recommend checking out some of the top attractions.

A top pick for your self-guided sightseeing tour today is Karlštejn Castle. Over 104,409 travelers visit this attraction every year. Previous visitors have rated this castle an average of 4.6 out of 5 stars in 23,287 reviews.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Prague.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Prague. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a wonderful meal at Restaurace Malostranská beseda, a top-rated dining spot in Prague. If you're in the mood for something new, try U Parlamentu, another premier location with a delectable menu. You might also want to book a table at Café Jen. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Prague.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in the Czech Republic.

On day 6 of your road trip in the Czech Republic, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Mezná, Děčín, Vysoká Lípa, and Harrachov. In the evening, you’ll end up in Špindlerův Mlýn, where you will stay for 1 night.

As you’ve unraveled the marvels of Ústí Nad Labem, it’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Mezná may take around 45 min. Upon your arrival in Mezná, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Journey into the unknown at Kamenice Gorge, a unique attraction awaiting your visit. This remarkable point of interest has an average rating of 4.8 out of 5 stars from 1,602 reviews.

Embrace the thrill of the open road as you wave goodbye to Mezná and set your GPS to Děčín. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 12 min. Upon reaching Děčín, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Take the opportunity to see České Švýcarsko National Park. This attraction has an average rating of 4.8 out of 5 stars from 17,415 visitors.

At the end of the day, you will drive to Špindlerův Mlýn, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Špindlerův Mlýn. If you are looking to dine at a popular restaurant in the village, it's often a good idea to reserve a table in advance.

Relax and recharge in preparation for another adventurous day in the Czech Republic!