One-Week the Czech Republic Self-Drive Road Trip With Itinerary from Prague to Ústí Nad Labem and Špindlerův Mlýn and surrounding area

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Photo of famous Charles Bridge over the Vltava river in Prague, Czech Republic.
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Explore the best of the Czech Republic on a 8-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Prague, Plzeň, Karlštejn, Průhonice, Kutná Hora, Ústí Nad Labem, Mezná, Děčín, Vysoká Lípa, Harrachov, Špindlerův Mlýn, Janské Lázně, and Dvůr Králové nad Labem. This road trip itinerary in the Czech Republic seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in the Czech Republic takes you through some of the best places to see in the country. You will spend 5 nights in Prague, 1 night in Ústí Nad Labem, and 1 night in Špindlerův Mlýn. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Prague, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Prague Castle and Charles Bridge are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Old Town Square, learn more about the unique St. Vitus Cathedral, and immerse yourself in the vibrant atmosphere of Prague Astronomical Clock.

As you hit the open road and drive through Prague, Plzeň, Karlštejn, Průhonice, Kutná Hora, Ústí Nad Labem, Mezná, Děčín, Vysoká Lípa, Harrachov, Špindlerův Mlýn, Janské Lázně, and Dvůr Králové nad Labem, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Charles Bridge
Prague CastleSt. Vitus CathedralDancing HouseVyšehradNational Museum in Prague
Petrin TowerPrague Astronomical ClockOld Town SquarePowder TowerPrague Zoo
Plzeň ZooCathedral of St. BartholomewPilsner Urquell BreweryKarlštejn Castle
Park PrůhoniceSt Barbara's CathedralItalian CourtSedlec Ossuary
Kamenice GorgeBohemian Switzerland National ParkDolský MlýnMumlava Falls
Špindlerův Mlýn Ski ResortKrkonoše National ParkThe Timber Trail, KrkonošeDvůr Králové Zoo
Letná Park

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Day 1

Day 1

  • Prague - Arrival day
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  • Charles Bridge
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Your road trip adventure in the Czech Republic begins as soon as you reach Prague and pick up your car. You’ll stay in Prague for 4 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Prague is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Charles Bridge, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Prague. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in the Czech Republic. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at U Tellerů, a top-rated dining destination in Prague. If you're in the mood to try something new, consider Restaurace U Bansethů, another top spot with a mouthwatering menu. You might also want to secure a reservation at Eska Restaurant and Bakery. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Prague this evening.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Anonymous Shrink's Office, a well-loved spot among locals and tourists. Or, head to Bar No. 7 - Prague. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Kontakt Bar, another top-rated place in the area.

Raise a toast to the start of your 8-day road trip in the Czech Republic!

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Day 2

Day 2

  • Prague
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Drive 15 km, 1 hour 5 min

  • Prague Castle
  • St. Vitus Cathedral
  • Dancing House
  • Vyšehrad
  • National Museum in Prague
  • More

Day 2 of your road trip across the Czech Republic promises a magnificent time exploring Prague. You have 3 nights left in Prague. Take the opportunity to experience more of the best attractions and activities in the city.

Prague is brimming with adventures. Today’s wonderful stops include a castle, a church, an art installation, a museum and much more! Begin your sightseeing adventure at the world-famous Prague Castle and allow yourself time to explore. Just a short distance away you'll find your next stop, St. Vitus Cathedral, an inviting church that draws visitors from far and near.

Continue your journey to Dancing House, one of the city’s most widely recognized spots that you shouldn’t miss. Another great site to visit is the notable Vyšehrad. When you're finished at the castle, Národní Muzeum (national Museum, Prague) awaits your visit. This museum is a history-steeped highlight on today's itinerary.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. The Czech Republic is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Prague. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delicious dinner at Brasileiro Restaurant, an excellent option for tonight's dining. Looking for something different? Restaurant Meat Beer offers a tantalizing alternative with its diverse menu. And don’t miss Restaurace Století. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Prague.

To truly maximize your evening out, consider visiting Bowla Bar after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to The Saints, another bar with an inviting ambiance. Similarly, Beergeek Bar also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Savor another day of unforgettable experiences in the Czech Republic!

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Day 3

Day 3

  • Prague
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Drive 27 km, 1 hour 4 min

  • Petrin Tower
  • Prague Astronomical Clock
  • Old Town Square
  • Powder Tower
  • Prague Zoo
  • More

On day 3 of your road trip, you will have an entire day to explore Prague. You’ll stay in Prague for 2 nights and discover all the best things to see and do in the area.

Discover a day packed with fun adventures, romantic experiences, and scenic views in Prague. Begin your sightseeing with Petřín Lookout Tower. This popular observation deck is one of the top attractions in the city. Proceed to Prague Astronomical Clock, another must-visit attraction.

As you wander through the inviting streets of Prague, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Old Town Square. This timeless public square is a traveler-favorite. Not far away, you’ll find Powder Tower, another key site on your sightseeing itinerary. Prague Zoo is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. The Czech Republic is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Prague, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Dine in style at BeBop Bar, a top recommendation for dinner tonight. Or, for a change of pace, Café restaurant Palanda boasts a menu that's sure to impress. Also, be sure to check out Restaurace Tiskárna. Known as a local hotspot, it’s a great choice for tonight in Prague.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Uhříněveský Bar stands out as an excellent choice for a post-dinner cocktail. Alternatively, Boothill Bar offers an ideal atmosphere to enjoy the pleasures of the night. Manesova Bar And Books is also a great option that provides a perfect setting for a relaxing evening.

Relax and recharge in preparation for another adventurous day in the Czech Republic!

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Day 4

Day 4

  • Prague
  • More

Drive 212 km, 3 hours 23 min

  • Plzeň Zoo
  • Cathedral of St. Bartholomew
  • Pilsner Urquell Brewery
  • Karlštejn Castle
  • More

On day 4 of your road trip, you’ll start and end your day in Prague, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Plzeň and Karlštejn. You still have 1 night left in Prague.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Prague allows for both. Start by heading to Dinopark Plzeň. This well-known zoo provides an insightful glimpse into the city's identity. Next, discover Cathedral Of St. Bartholomew, a majestic church, promising a delightful encounter.

Continue your sightseeing with a visit to Pilsner Urquell Brewery, an intriguing brewery. When you’re done, don’t forget to make a stop at the interesting Karlštejn Castle.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Prague.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Prague. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delightful dinner at OSSEGG Praha - Pivovar & Restaurace, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try U Fleků? It's another excellent option with a diverse menu. Consider reserving a table at Havelská Koruna as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Prague.

After savoring a delicious meal, step into the vibrant nightlife at Bar Bohužel, where the evening is just getting started. In the same way, Hemingway Bar offers a unique charm perfect for experiencing the local bar scene in Prague. Bar Tečka is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Relax and recharge in preparation for another adventurous day in the Czech Republic!

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Day 5

Day 5

  • Prague
  • Ústí nad Labem
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Drive 236 km, 3 hours 29 min

  • Park Průhonice
  • St Barbara's Cathedral
  • Italian Court
  • Sedlec Ossuary
  • More

Dive into day 5 of your remarkable road trip in the Czech Republic. Today you will explore Průhonice and Kutná Hora, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Ústí Nad Labem. You’ll stay here for 1 night.

Prepare for a day full of fun adventures, romantic experiences, and natural wonders. When you’re ready, kick off your sightseeing adventure at Park Průhonice. This frequently visited botanical garden is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is St Barbara's Cathedral, one of the village’s best highlights.

Next, check out Italian Court, one of the most up-and-coming places to see in Prague. This castle is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Sedlec Ossuary. Wander around and soak in the heritage-rich atmosphere this church offers.

When you’re done exploring for the day, you’ll drive to your hotel in Ústí Nad Labem. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Ústí Nad Labem. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Make sure to reserve a table at Restaurant Větruše, an iconic dining spot in Ústí Nad Labem. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Hotel a Restaurant Větruše, a popular restaurant in Ústí Nad Labem. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of BLACKSHEEP BAR, a hidden gem nestled in Ústí Nad Labem. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Explore the vibrant nightlife at Hp Bar after your meal, a hub for lively evenings and memorable moments. Or, head to Ústecká Pivotéka for a great selection of flavorful drinks and a charming setting. Furthermore, Pubs Bar Hamburg is perfect for those looking to extend their night with a touch of local flavor.

Get a good night's sleep and look forward to another great day on the road in the Czech Republic!

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Day 6

Day 6

  • Ústí nad Labem
  • Špindlerův Mlýn
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Drive 217 km, 4 hours 16 min

  • Kamenice Gorge
  • Bohemian Switzerland National Park
  • Dolský Mlýn
  • Mumlava Falls
  • More

Embark on another extraordinary experience on day 6 of your road trip in the Czech Republic. Today, you will make 4 stops and experience some of the highlights of Mezná, Děčín, Vysoká Lípa, and Harrachov. At the end of the day, you will enjoy the comforts of a top-rated hotel in Špindlerův Mlýn, which will be your home away from home for 1 night.

Get ready for an exciting day in Ústí Nad Labem. Today’s sightseeing agenda includes a canyon, a national park, a historical landmark, a waterfall and much more! Begin your adventure at Kamenice Gorge. This is a curiosity-inducing canyon you should not miss. Another must-see is České Švýcarsko National Park, a notable national park in Ústí Nad Labem.

When you’re ready for the next sight, head to Dolský Mlýn. From there, take a leisurely stroll to Mumlava Falls, another of the village’s captivating attractions.

At the end of the day, you will drive to Špindlerův Mlýn, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Špindlerův Mlýn. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Take some time to reflect on your day and savor another beautiful night in the Czech Republic.

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Day 7

Day 7

  • Špindlerův Mlýn
  • Prague
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Drive 232 km, 3 hours 28 min

  • Špindlerův Mlýn Ski Resort
  • Krkonoše National Park
  • The Timber Trail, Krkonoše
  • Dvůr Králové Zoo
  • More

On day 7 of your road trip in the Czech Republic, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Špindlerův Mlýn, Janské Lázně, and Dvůr Králové nad Labem. In the evening, you’ll end up in Prague, where you will stay for 1 night.

Immerse yourself in Špindlerův Mlýn’s rich culture with today's sightseeing itinerary. Start your journey at Špindlerův Mlýn Ski Resort. This majestic ski resort is sure to ignite your curiosity. Next, dive into the peaceful features of Krkonoše National Park, a must-visit national park in the village.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to The Timber Trail, Krkonoše, a captivating canopy walk. For a change of scene, check out Dvůr Králové Zoo, known for its visually striking features.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Prague. Prague offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Prague. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Dine in style at MAURIZIO restaurant & café, a top recommendation for dinner tonight. Or, for a change of pace, Gate Restaurant boasts a menu that's sure to impress. Also, be sure to check out U Houmra. Known as a local hotspot, it’s a great choice for tonight in Prague.

Continue the enjoyment post-dinner at Crazy Daisy, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Puerto Rico Cafe & Cocktail Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Anonymous Bar. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in the Czech Republic.

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Day 8

Day 8

  • Prague - Departure day
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  • Letná Park
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Day 8 of your road trip in the Czech Republic is your departure day. This is your chance to catch a last glimpse of Prague before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Letná Park, a serene park before you head out.

Maximize your last day in the Czech Republic and go on a shopping spree in Prague’s shopping center, the lively Wenceslas Square. Browse for souvenirs to remind you of your wonderful journey in the Czech Republic.

Before you conclude your road trip in the Czech Republic, drop by another restaurant for a last chance at a memorable dining experience in Prague.

Dine in style at Restaurace U Jindřišské věže, a top recommendation for dinner tonight. Or, for a change of pace, The Grand Mark Prague boasts a menu that's sure to impress.

You’ll then say farewell to Prague. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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