One-Week the Czech Republic Self-Drive Road Trip With Itinerary from Prague traveling south to Český Krumlov and Brno

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Photo of famous Charles Bridge over the Vltava river in Prague, Czech Republic.
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Explore the best of the Czech Republic on a remarkable 8-day road trip! Combine exploration with relaxation on a self-drive tour featuring Prague, Karlštejn, Hostim, Beroun, Český Krumlov, Hluboká nad Vltavou, Třeboň, Telč, Brno, and Kutná Hora.

This perfectly planned road trip itinerary takes you through some of the best places to see in the Czech Republic. You will spend 4 nights in Prague, 2 nights in Český Krumlov, and 1 night in Brno. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in the Czech Republic. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Prague, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover the Czech Republic on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in the Czech Republic. Prague Castle and Charles Bridge are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Prague, Karlštejn, Hostim, Beroun, Český Krumlov, Hluboká nad Vltavou, Třeboň, Telč, Brno, and Kutná Hora, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of the Czech Republic. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in the Czech Republic.

Throughout your road trip in the Czech Republic, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in the Czech Republic.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in the Czech Republic fill up quickly, so book your spot early. Select a date and start planning your road trip in the Czech Republic today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day1

Day 1

  • Prague - Arrival day
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  • Malá Strana
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Welcome to Prague, the perfect starting point for your road trip in the Czech Republic! Pick up your rental car and let the adventure begin. You will spend 3 nights discovering what to see in Prague before embarking on the next leg of your journey.

Prague is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Prague. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in the Czech Republic. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Prague, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at U Tellerů, a top-rated dining destination in Prague. If you're in the mood to try something new, consider Restaurace U Bansethů, another top spot with a mouthwatering menu. You might also want to secure a reservation at Eska Restaurant and Bakery. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Prague this evening.

If you’re not ready to end the night just yet, Anonymous Shrink's Office offers a perfect venue to relax and savor a drink. Similarly, Bar No. 7 - Prague is well-suited for those looking to unwind in a social setting. Kontakt Bar is another excellent spot to enjoy a nightcap after a delightful meal.

Raise a toast to the start of your 8-day road trip in the Czech Republic!

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Day2

Day 2

  • Prague
  • More

Drive 6 km, 58 min

  • Prague Castle
  • St. Vitus Cathedral
  • National Technical Museum
  • Old Town Square
  • Staré Město
  • More

Day 2 of your road trip will take you to the best attractions Prague has to offer. Cherish the 2 nights you have left in the city and use the provided itinerary to discover what to see in Prague.

Don’t miss Staré Město today, a must-see neighborhood that offers a glimpse into the city’s vibrant character. Take your time to explore its best features, and enjoy the convenience of nearby top-rated landmarks.

Prague Castle is must-visit castle and a great option for a daytime tour of the area. Continue your journey to St. Vitus Cathedral, a spectacular church, located just a leisurely stroll away. Next, head to National Technical Museum, a history-steeped museum, also available for your discovery today.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in the Czech Republic. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Prague's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy a lovely dining experience at Brasileiro Restaurant, a popular restaurant in Prague. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Prague at Restaurant Meat Beer, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Restaurace Století. It’s yet another ideal choice to enhance your time in Prague tonight.

Cap off your dinner by heading to Bowla Bar, ideal for a leisurely evening with a drink in hand. The Saints is another bar that offers an enjoyable setting. Similarly, Beergeek Bar is also a popular place to go on a night out, perfect for relaxing and socializing.

Get a good night's sleep and look forward to another great day on the road in the Czech Republic!

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Day3

Day 3

  • Prague
  • More

Drive 90 km, 2 hours 25 min

  • Karlštejn Castle
  • Chráněná krajinná oblast Český kras
  • Lom Alkazar (Hostim I)
  • Husovo náměstí, Beroun
  • Medvědárium Beroun
  • More

On day 3 of your road trip in the Czech Republic, you’ll start and end your day in Prague, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Prague, there’s no need to rush. Experience Karlštejn, Hostim, and Beroun to the fullest today with this curated day itinerary.

Check out the locally renowned castle, Karlštejn Castle. Afterward, continue to Chráněná Krajinná Oblast Český Kras, a nature reserve every traveler should visit. As you explore Prague’s charming streets, take in the lively atmosphere and get to know the character of the village.

Next, make your way to Lom Alkazar. This frequently visited cave is an essential stop. Following that, head to Husovo Náměstí, Beroun, another must-visit site that will enhance your experience. Don’t forget to stop by Medvědárium Beroun, a worthwhile zoo in the village.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Prague.

Indulge in a memorable dining experience at one of Prague's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a delicious dinner at BeBop Bar, an excellent option for tonight's dining. Looking for something different? Café restaurant Palanda offers a tantalizing alternative with its diverse menu. And don’t miss Restaurace Tiskárna. Known for great service, it’s a fantastic choice for tonight in Prague.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Uhříněveský Bar stands out as an excellent choice for a post-dinner cocktail. Alternatively, Boothill Bar offers an ideal atmosphere to enjoy the pleasures of the night. Manesova Bar And Books is also a great option that provides a perfect setting for a relaxing evening.

Celebrate another amazing day of your road trip adventure in the Czech Republic!

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Day4

Day 4

  • Prague
  • Český Krumlov
  • More

Drive 176 km, 2 hours 36 min

  • Monastery of the Minorites
  • State Castle and Chateau Český Krumlov
  • Český Krumlov Castle Tower
  • Lazebnický most
  • Egon Schiele Art Centrum
  • More

Dive into day 4 of your remarkable road trip in the Czech Republic. Today you'll explore 1 destination, including Český Krumlov. At the end of the day, you’ll unwind at one of the finest accommodations in Český Krumlov, where you'll spend 2 nights.

Make time for Monastery Of The Minorites, an often recommended monastery that is worthwhile a visit in the town. Nearby, you’ll find Český Krumlov Castle, enchanting visitors with its history-steeped appeal. Continue your exploration at Český Krumlov Castle Tower. This castle is one of the town’s most up-and-coming spots.

Enjoy the freedom of exploring Prague at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Lazebnický Most. After exploring the bridge, head to the curiosity-inducing Egon Schiele Art Centrum.

At the end of the day, you will drive to Český Krumlov, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Český Krumlov. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Raise your glass and celebrate another amazing day of your road trip in the Czech Republic!

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Day5

Day 5

  • Český Krumlov
  • More

Drive 118 km, 2 hours 20 min

  • The State Chateau of Hluboká
  • Kostel svatého Jana Nepomuckého
  • Ohrada Zoo
  • State Chateau Trebon
  • More

On day 5 of your road trip, you’ll start and end your day in Český Krumlov, where you have 1 night left to stay.

Hluboká nad Vltavou is brimming with adventures.

Look forward to a unique sightseeing adventure at the notable The State Chateau Of Hluboká and allow yourself time to explore. Just a short distance away you'll find your next stop, Kostel Svatého Jana Nepomuckého, an instagrammable church that draws visitors from far and near.

Continue your journey to Ohrada Zoo, one of the town’s most popular spots that you shouldn’t miss. Another great site to visit is the often recommended State Chateau Trebon.

When you’re done exploring for the day, you’ll return to Český Krumlov and your accommodation.

Český Krumlov is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Český Krumlov.

As the sun sets, rest up and recharge for the next leg of your road trip in the Czech Republic.

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Day6

Day 6

  • Český Krumlov
  • Brno
  • More

Drive 246 km, 3 hours 59 min

  • Telč château
  • Villa Tugendhat
  • cathedral of St. Peter and Paul
  • Špilberk Castle
  • More

Your itinerary for day 6 of your road trip in the Czech Republic includes 2 stops and features some of the highlights of Telč and Brno. At the end of the day, enjoy the comforts of a top-rated hotel in Brno, where you'll spend 1 night.

Whatever your travel style is, Telč Château is an essential stop in Český Krumlov. This frequently visited castle provides an insightful glimpse into the town's identity. Next, discover Villa Tugendhat, a historic museum, promising a delightful encounter.

Continue your sightseeing with a visit to Cathedral Of St. Peter And Paul, an underrated church. When you’re done, don’t forget to make a stop at the well-known Špilberk Castle.

When you’re done exploring for the day, you’ll drive to your hotel in Brno. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Brno. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a lovely dining experience at U Štíra, a popular restaurant in Brno. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Brno at Bistro Franz, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Noem Arch Restaurant. It’s yet another ideal choice to enhance your time in Brno tonight.

Cap off your dinner by heading to Bar Naproti, ideal for a leisurely evening with a drink in hand. Super Panda Circus is another bar that offers an enjoyable setting. Similarly, Výčep Na Stojáka is also a popular place to go on a night out, perfect for relaxing and socializing.

Head back to your accommodation in Brno and get some rest to prepare for another magical day of your road trip in the Czech Republic.

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Day7

Day 7

  • Brno
  • Prague
  • More

Drive 243 km, 3 hours 42 min

  • Geologická expozice Čížkova skála
  • St Barbara's Cathedral
  • Gothic Stone Fountain
  • Italian Court
  • Breuer Gardens
  • Sedlec Ossuary
  • More

Experience an unparalleled adventure on day 7 of your road trip in the Czech Republic. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Kutná Hora. At the end of the day, you will retreat to the hotel of your choice in Prague, where will spend 1 night.

Look forward to a unique sightseeing adventure at the frequently visited Geologická Expozice Čížkova Skála and allow yourself time to explore. Just a short distance away you'll find your next stop, St Barbara's Cathedral, an inviting church that draws visitors from far and near.

Continue your journey to Stone Fountain, one of the town’s most beloved spots that you shouldn’t miss. Another great site to visit is the intriguing Italian Court. When you're finished at the castle, Breuer Gardens awaits your visit. Last up is a church - the captivating Sedlec Ossuary.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Prague. Prague offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Prague is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Prague.

Treat yourself to a delightful dinner at OSSEGG Praha - Pivovar & Restaurace, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try U Fleků? It's another excellent option with a diverse menu. Consider reserving a table at Havelská Koruna as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Prague.

After enjoying a fulfilling meal, continue your evening at Bar Bohužel, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Hemingway Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Tečka provides an excellent environment for a relaxed and enjoyable evening.

Celebrate another amazing day of your road trip adventure in the Czech Republic!

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Day8

Day 8

  • Prague - Departure day
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  • Charles Bridge
  • More

Day 8 of your road trip in the Czech Republic is your departure day. This is your chance to catch a last glimpse of Prague before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Charles Bridge, a romantic historical landmark before you head out.

Take advantage of your accommodation's proximity to Prague’s shopping district for some last-minute bargain hunting. Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in the Czech Republic, drop by another restaurant for a last chance at a memorable dining experience in Prague.

You’ll then say farewell to Prague. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in the Czech Republic!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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