10-Day France Self-Drive Road Trip With Itinerary from Lyon traveling south to Avignon

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Photo of summer view over Vieux Lyon, with famous cathedral Fourviere, and Croix Rousse in Lyon, France.
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Explore the best of France on a remarkable 10-day road trip! Combine exploration with relaxation on a self-drive tour featuring Lyon, Caluire-et-Cuire, Annecy, Chamonix Mont Blanc, Grenoble, Avignon, Arles, Aix-en-Provence, Cassis, and Vienne.

This perfectly planned road trip itinerary takes you through some of the best places to see in France. You will spend 6 nights in Lyon and 3 nights in Avignon. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in France. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Lyon, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover France on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in France. Parc De La Tête D'or and Palais Des Papes are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Lyon, Caluire-et-Cuire, Annecy, Chamonix Mont Blanc, Grenoble, Avignon, Arles, Aix-en-Provence, Cassis, and Vienne, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of France. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in France.

Throughout your road trip in France, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in France.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in France fill up quickly, so book your spot early. Select a date and start planning your road trip in France today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day1

Day 1

  • Lyon - Arrival day
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  • Place Bellecour
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Say hello to Lyon! Your exciting road trip through France is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Lyon for 5 nights before you continue your adventure!

Lyon is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Place Bellecour. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Lyon. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Lyon, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Nuage café, an iconic dining spot in Lyon. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Café du Rhône, a popular restaurant in Lyon. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Agastache Restaurant, a hidden gem nestled in Lyon. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After savoring a delicious meal, step into the vibrant nightlife at L' Antiquaire, where the evening is just getting started. In the same way, Black Forest Society offers a unique charm perfect for experiencing the local bar scene in Lyon. Pompette is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise a toast to the start of your 10-day road trip in France!

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Day2

Day 2

  • Lyon
  • More

Drive 21 km, 1 hour 22 min

  • parc de la Tête d'Or
  • Fresque des Lyonnais
  • Lyon Cathedral
  • La Basilique Notre Dame de Fourvière
  • La Croix-Rousse
  • Vieux Lyon
  • More

On day 2 of your road trip, you’ll start and end your day in Lyon, where you still have 4 nights left. You'll spend part of the day exploring places of interest outside the immediate city, including Caluire-et-Cuire and Lyon.

Caluire-et-Cuire is brimming with adventures. La Croix-Rousse is a neighborhood that stands out as one of the must-see places in Caluire-et-Cuire. Take a moment to explore its distinct atmosphere, and don’t miss the popular sightseeing spots just a short walk away. For another highlight, head to Vieux Lyon, a neighborhood offering its own unique experiences.

To truly experience Lyon, make sure to drop by Parc De La Tête D'or. This impressive park is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Fresque Des Lyonnais, one of the town’s best highlights.

Next, check out Lyon Cathedral, one of the most interesting places to see in Lyon. This church is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Basilica Of Notre-dame De Fourvière. Wander around and soak in the grand atmosphere this church offers.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Lyon.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Lyon. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Bulle - Restaurant de Fourvière - Guy Lassausaie, a top-rated dining destination in Lyon. If you're in the mood to try something new, consider Bernachon Chocolats, another top spot with a mouthwatering menu. You might also want to secure a reservation at La Mère Léa. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Lyon this evening.

Let the evening flow smoothly from dinner to drinks at The James Joyce Pub, a top-rated bar in the area. For other recommendations, Broc'bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, La Passagère offers a memorable night with diverse drink options and excellent service.

As the sun sets, rest up and recharge for the next leg of your road trip in France.

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Day3

Day 3

  • Lyon
  • More

Drive 312 km, 3 hours 53 min

  • Jardins de l'Europe d'Annecy
  • Pont des Amours
  • Le Pâquier d'Annecy
  • Lac d'Annecy
  • More

Greet day 3 of your road trip in France with a smile and start your day with a hearty breakfast. You have 3 nights to stay in Lyon, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Annecy.

Jardins De L'europe D'annecy makes a great addition to your morning plans. This curiosity-inducing park is a romantic place to see in Lyon.

As you stroll around Lyon, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Le Pâquier D'annecy. This beloved park offers a romantic encounter with Lyon. Next, make your way to Lake Annecy to add another highlight to your day. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Lyon.

When you’re done exploring for the day, you’ll return to Lyon and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Lyon. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a wonderful meal at Nosch, a top-rated dining spot in Lyon. If you're in the mood for something new, try Auberge des canuts - Bouchon Lyonnais, another premier location with a delectable menu. You might also want to book a table at Vieille Canaille. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Lyon.

Keep the evening going at La Raffinerie, a great choice for enjoying the after-dinner hours with a drink. You could also go to Bar Le Florian, Cocktails & Spirits, which offers a similarly pleasant setting and great drinks. Another option is Mos - Maker Of Stories, which provides an inviting environment for unwinding after a busy day out.

Celebrate another amazing day of your road trip adventure in France!

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Day4

Day 4

  • Lyon
  • More

Drive 464 km, 5 hours 8 min

  • Le Pas dans le Vide
  • Aiguille du Midi
  • MUSEE DES CRISTAUX - EspaceTairraz (en Rénovation)
  • More

On day 4 of your road trip, you’ll start and end your day in Lyon, where you have 2 nights left to stay.

Le Pas Dans Le Vide is an ideal stop early in the day. This beloved observation deck is a must-visit in the region. When you’re ready for your next discovery, continue to Aiguille Du Midi, which may be one of the most romantic places you will experience today.

One of the best things about exploring Lyon on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Musee Des Cristaux - Espacetairraz, a worthwhile museum in the region.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Lyon.

Lyon is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Lyon.

Enjoy a lovely meal at Restaurant Le Parloir, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Café Terroir is another top choice with a popular menu. You could also check for a table at Cactus Bar. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Lyon tonight.

Explore the vibrant nightlife at Le Dôme after your meal, a hub for lively evenings and memorable moments.

Savor another day of unforgettable experiences in France!

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Day5

Day 5

  • Lyon
  • More

Drive 235 km, 3 hours 50 min

  • Bastille
  • Jardin des Dauphins
  • Téléphérique Grenoble - Bastille
  • Fontaine du Lion
  • Museum of Grenoble
  • More

On day 5 of your road trip, you'll get the chance to experience Grenoble. At the end of the day, you'll drive back to Lyon, where you still have 1 night left to stay.

Make a stop at Fort De La Bastille. This beloved castle is a must-visit for travelers looking for a unique holiday experience. Make your way to Jardin Des Dauphins located in Lyon for another exciting encounter.

Next, immerse yourself in the setting of Téléphérique Grenoble - Bastille. Its visually striking features will captivate you. After the tramway, continue your tour of the city with a visit to Fontaine Du Lion. Visitors usually appreciate the heritage-rich features of this monument. Next up is Musée De Grenoble, a highly recommended museum.

When you’re done exploring for the day, you’ll return to Lyon and your accommodation.

Indulge in a memorable dining experience at one of Lyon's most popular restaurants, and connect with friendly locals for a true cultural experience.

Have a fantastic dining experience at Pho 69, a highly recommended choice for tonight's dinner. If you're looking to mix things up, L Bar food & drink offers an enticing alternative with its varied menu. Additionally, Le François Villon is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Lyon.

Raise your glass and celebrate another amazing day of your road trip in France!

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Day6

Day 6

  • Lyon
  • Avignon
  • More

Drive 230 km, 2 hours 52 min

  • Jardin des doms
  • Palais des Papes
  • Remparts d'Avignon
  • Collection Lambert Avignon
  • Musée Lapidaire
  • More

Dive into day 6 of your remarkable road trip in France. Today you'll explore 1 destination, including Avignon. At the end of the day, you’ll unwind at one of the finest accommodations in Avignon, where you'll spend 3 nights.

Awaiting your discovery is the curiosity-inducing Jardin Des Doms, an enchanting park in Lyon. Next, go to Palais Des Papes.

After visiting Jardin Des Doms and Palais Des Papes, have a stroll along Lyon's streets and take in the local charm. Continue your sightseeing by heading to Remparts D'avignon. This culturally significant historical landmark offers a unique experience. Hotel Caumont is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Musée Lapidaire D'avignon, one of the most instagrammable places to visit in Lyon.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Avignon. Avignon offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Avignon is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Avignon.

Savor the flavors at Restaurant Pollen, a top pick for dinner tonight. Alternatively, Chez Bodus Le Garçon Boucher beckons with its unique menu offerings. Also, consider La Cuisine de Papa. With its consistent customer satisfaction, it’s an excellent option for dining in Avignon tonight.

Continue your lively evening at Le 17 Place Aux Vins Avignon • Bar À Vin / Caviste, a perfect place for winding down or revving up the night, depending on which mood you’re in. Barberousse Avignon is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, The Red Sky ensures a night out tailored to your taste.

Raise your glass to another unforgettable day in France!

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Day7

Day 7

  • Avignon
  • More

Drive 109 km, 2 hours 26 min

  • Pont du Gard
  • Pont du Gard Museum
  • L'espace Van Gogh
  • Obélisque d'Arles
  • Saint-Trophime Primatial Catholic Church
  • Arles Amphitheatre
  • More

On day 7 of your road trip in France, you’ll start and end your day in Avignon, but spend the day exploring what’s beyond the city. Since you still have 2 nights to spend in Avignon, there’s no need to rush. Experience La Bégude de Vers-Pont-du-Gard and Arles to the fullest today with this curated day itinerary.

Catch Pont Du Gard before the crowds roll in. This history-steeped monument is sure to ignite your curiosity. Next, dive into the picture-perfect features of Pont Du Gard Museum, a must-visit museum in the hamlet.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to L'espace Van Gogh, an increasingly popular cultural center. For a change of scene, check out Obélisque D'arles, known for its noteworthy features. We also recommend visiting Saint-trophime Primatial Catholic Church. This church is a must for anyone looking to experience the hamlet to the fullest. Lastly, end your day with a visit to Arles Amphitheatre, yet another popular attraction in Avignon.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Avignon.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Avignon, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at Le Carré du Palais, a popular restaurant in Avignon. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Avignon at Avenio, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated BAR DU CHANGE. It’s yet another ideal choice to enhance your time in Avignon tonight.

Round off your dining experience by visiting O'collins's Irish Pub, a prime location for a drink. Alternatively, explore the distinctive characteristics of The Gambrinus, a bar catering to every mood and preference.

Relax and recharge in preparation for another adventurous day in France!

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Day8

Day 8

  • Avignon
  • More

Drive 179 km, 2 hours 50 min

  • Paroisse Cathédrale Saint Sauveur Aix-en-Provence
  • forum des Cardeurs
  • Fontaine de la Rotonde
  • Hôtel de Caumont
  • Musée Granet
  • Cours Mirabeau
  • More

Wake up to day 8 of your road trip in France. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Aix-en-Provence. With 1 night to stay in Avignon, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Set aside time today to explore Cours Mirabeau, a standout street that reflects the essence of the city. While you're there, you'll also be within reach of some of the city's top landmarks, making it easy to maximize your day.

Awaiting your discovery is the beloved Paroisse Cathédrale Saint Sauveur Aix-en-provence, a grand church in Avignon. Next, go to Place Des Cardeurs.

After visiting Paroisse Cathédrale Saint Sauveur Aix-en-provence and Place Des Cardeurs, have a stroll along Avignon's streets and take in the local charm. Continue your sightseeing by heading to Fontaine De La Rotonde. This noteworthy monument offers a unique experience. Hôtel De Caumont is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Musée Granet, one of the most photogenic places to visit in Avignon.

When you’re done exploring for the day, you’ll return to Avignon and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Avignon's best restaurants.

Treat yourself to a delicious dinner at Bar La place ☀️ Terrasse 🍸 Cocktail 🎶 Music, an excellent option for tonight's dining. Looking for something different? Vivotto Avignon offers a tantalizing alternative with its diverse menu. And don’t miss Ma belle cuisine. Known for great service, it’s a fantastic choice for tonight in Avignon.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in France.

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Day9

Day 9

  • Avignon
  • Lyon
  • More

Drive 482 km, 5 hours 42 min

  • Calanque de Port-Miou
  • Ville Garden
  • Roman Temple of Augustus and Livia
  • More

Experience an unparalleled adventure on day 9 of your road trip in France. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Cassis and Vienne. At the end of the day, you will retreat to the hotel of your choice in Lyon, where will spend 1 night.

Catch Calanque De Port-miou before the crowds roll in. This stunning marina is sure to ignite your curiosity.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Roman Temple Of Augustus And Livia, an often recommended monument.

At the end of the day, you will drive to Lyon, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Lyon. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Make sure to reserve a table at NEWTREE Café Bellecour, an iconic dining spot in Lyon. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Le Garet, a popular restaurant in Lyon. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Le Mirtillo, a hidden gem nestled in Lyon. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Say good night to Lyon and look forward to another great day of your road trip in France!

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Day10

Day 10

  • Lyon - Departure day
  • More
  • Porte des Enfants du Rhône
  • More

Day 10 of your road trip in France is your departure day. This is your chance to catch a last glimpse of Lyon before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Porte Des Enfants Du Rhône, a noteworthy monument before you head out.

Take advantage of your accommodation's proximity to Lyon’s shopping district for some last-minute bargain hunting. Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in France, drop by another restaurant for a last chance at a memorable dining experience in Lyon.

You’ll then say farewell to Lyon. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in France!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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