12-Day France Self-Drive Road Trip With Itinerary from Grenoble to Avignon, Nice, and Lyon and surrounding area
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Escape the ordinary with this exciting 12-day road trip through France. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!
This perfectly planned road trip itinerary in France takes you through some of the best places to see in the country. You will spend 2 nights in Grenoble, 3 nights in Avignon, 3 nights in Nice, and 3 nights in Lyon. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in France. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Grenoble, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover France on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in France. Parc De La Tête D'or and Palais Des Papes are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Monte Carlo Casino, learn more about the unique Pont Du Gard, and immerse yourself in the vibrant atmosphere of Musée Océanographique De Monaco.
As you hit the open road and drive through Grenoble, Avignon, Fontaine-de-Vaucluse, Roussillon, Nimes, Arles, Nice, Monaco, Cannes, Vallauris, La Mulatière, Lyon, Beaujeu, Caluire-et-Cuire, Choranche, Vassieux-en-Vercors, and Pont-en-Royans, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of France. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in France.
Throughout your road trip in France, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in France.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in France fill up quickly, so book your spot early. Select a date and start planning your road trip in France today!
Itinerary summary
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Day 1
- Grenoble - Arrival day
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- Fontaine du Lion
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Your road trip adventure in France begins as soon as you reach Grenoble and pick up your car. You’ll stay in Grenoble for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.
Grenoble is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Fontaine Du Lion, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Grenoble. Make yourself at home and enjoy some downtime before heading out again.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Grenoble, it's often a good idea to reserve a table in advance.
Dine in style at Restaurant Le Rousseau, a top recommendation for dinner tonight. Or, for a change of pace, Bar Au RENCARD boasts a menu that's sure to impress. Also, be sure to check out Ciao a Te. Known as a local hotspot, it’s a great choice for tonight in Grenoble.
After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Le Groove, a well-loved spot among locals and tourists. Or, head to Brasserie La Natation. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Pub Shakesbeer, another top-rated place in the area.
Raise a toast to the start of your 12-day road trip in France!
Day 2
- Grenoble
- Avignon
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Drive 223 km, 2 hours 42 min
- Remparts d'Avignon
- Collection Lambert Avignon
- Palais des Papes
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Dive into day 2 of your remarkable road trip in France. Today you will explore Avignon, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Avignon. You’ll stay here for 3 nights.
Prepare for a day full of family-friendly attractions, breathtaking views, and picturesque spots. When you’re ready, kick off your sightseeing adventure at Remparts D'avignon. This increasingly popular historical landmark is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Hotel Caumont, one of the city’s best highlights.
Next, check out Palais Des Papes, one of the most well-known places to see in Grenoble. This palace is a favorite among locals and travelers alike.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Avignon. Avignon offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Avignon. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Enjoy a delicious meal at Restaurant Pollen, a top-rated dining destination in Avignon. If you're in the mood to try something new, consider Chez Bodus Le Garçon Boucher, another top spot with a mouthwatering menu. You might also want to secure a reservation at La Cuisine de Papa. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Avignon this evening.
After your meal, keep the night alive at a bar like Le 17 Place Aux Vins Avignon • Bar À Vin / Caviste, known for its lively atmosphere. Barberousse Avignon is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, The Red Sky offers an excellent atmosphere for those looking to amp up the evening.
Take some time to reflect on your day and savor another beautiful night in France.
Day 3
- Avignon
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Drive 113 km, 2 hours 49 min
- Vaucluse Spring
- Château de Philippe de Cabassolle
- Le Sentier des Ocres
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Greet day 3 of your road trip in France with a smile and start your day with a hearty breakfast. You will return to Avignon for your remaining 2 nights in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Fontaine-de-Vaucluse and Roussillon.
Bring your curiosity for today’s adventure around Avignon. Some of the village’s most loved attractions await! Vaucluse Spring is the perfect place to start. This sightseeing destination is one of the most frequently visited places to visit in Avignon. Next, head to Château De Philippe De Cabassolle, a beloved castle, known for its heritage-rich features.
In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Le Sentier Des Ocres. This romantic hiking area is a highly recommended experience. Visit these for an interesting touch to your journey.
When you’re done exploring for the day, you’ll return to Avignon and your accommodation.
After a day of adventure, treat yourself to an exquisite dinner at one of Avignon's best restaurants.
Enjoy a lovely dining experience at Le Carré du Palais, a popular restaurant in Avignon. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Avignon at Avenio, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated BAR DU CHANGE. It’s yet another ideal choice to enhance your time in Avignon tonight.
Continue your evening by exploring the vibrant nightlife scene at O'collins's Irish Pub, a prime destination for a thrilling night out. Also, don’t forget to check out The Gambrinus, a bar that offers unique local touches.
Celebrate another amazing day of your road trip adventure in France!
Day 4
- Avignon
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Drive 139 km, 2 hours 58 min
- Pont du Gard
- Jardin de La Fontaine
- Musée des beaux-arts de Nîmes
- Roman Theatre of Arles
- Arles Amphitheatre
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On day 4 of your road trip, you’ll start and end your day in Avignon, where you'll stay for 1 night more.
Immerse yourself in Avignon’s rich culture with today's sightseeing itinerary. Start your journey at Pont Du Gard. This visually striking monument is sure to ignite your curiosity. Next, dive into the visually striking features of Jardin De La Fontaine, a must-visit park in the hamlet.
In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Musée Des Beaux-arts De Nîmes, a frequently visited museum. For a change of scene, check out Roman Theatre Of Arles, known for its picture-perfect features. We also recommend visiting Arles Amphitheatre. This archeological site is a must for anyone looking to experience the hamlet to the fullest.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Avignon.
As you explore more of Avignon, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Don’t miss out on dining at Bar La place ☀️ Terrasse 🍸 Cocktail 🎶 Music, a top-rated dining destination in Avignon. If you're in the mood to try something new, consider Vivotto Avignon, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ma belle cuisine. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Avignon this evening.
Head back to your accommodation in Avignon and get some rest in preparation for another magical day of your road trip in France!
Day 5
- Avignon
- Nice
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Drive 264 km, 3 hours 18 min
- Castle Hill
- Ascenseur du Château
- Fontaine du Soleil
- place Masséna
- Promenade du Paillon
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On day 5 of your road trip in France, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Nice. In the evening, you’ll end up in Nice, where you will stay for 3 nights.
Today's adventure in Avignon promises more breathtaking discoveries and enriching experiences! Begin at Castle Hill. This mesmerizing park is a highlight of any visit in the city. Then, enjoy Ascenseur Du Château, another visually striking attraction that never fails to captivate visitors. Next, head over to Fontaine Du Soleil, one of the city’s most locally appreciated attractions, known for its breathtaking features.
If you’re looking for more, spend time soaking in the atmosphere of Place Masséna. This awe-inspiring public square is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Promenade Du Paillon, a worthwhile park, and take a stroll around the area.
When you’re done exploring for the day, you’ll drive to your hotel in Nice. Check in and spend some time relaxing before you head out to tour the city.
Indulge in a memorable dining experience at one of Nice's most popular restaurants, and connect with friendly locals for an authentic adventure.
Enjoy a lovely meal at Le Bocal, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Le Makassar is another top choice with a popular menu. You could also check for a table at Les Amoureux. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Nice tonight.
Unwind after your meal by stepping into Les Distilleries Idéales. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Diane's offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Wayne's Bar, another top-rated bar in the area.
Relax and reminisce about your day in France and look forward to more memorable moments to come!
Day 6
- Nice
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Drive 44 km, 1 hour 46 min
- Musée océanographique de Monaco
- Cathedral of Our Lady Immaculate
- Prince's Palace of Monaco
- Monte Carlo Casino
- Eze village France 🇫🇷
- Église Notre-Dame-de-l'Assomption
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On day 6 of your road trip, you’ll start and end your day in Nice, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Monaco and Nice. You still have 2 nights left in Nice.
Start your adventure at Musée Océanographique De Monaco. This notable aquarium is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the inviting wonders of Cathedral Of Our Lady Immaculate, a must-see church in the city.
Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Prince's Palace Of Monaco. This popular palace offers an enriching experience. For a change of pace, head to Monte Carlo Casino, where you can take in enchanting features. Conclude your self-guided sightseeing tour with a visit to Eze Village France and Église Notre-dame-de-l'assomption. These sights offer a fulfilling end to a perfect day.
When you’re done exploring for the day, you’ll return to Nice and your accommodation.
As dinnertime approaches, it's time to head out for a bite to eat in Nice. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Make sure to reserve a table at Le Windsor Jungle Art Hotel, an iconic dining spot in Nice. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Snug And Cellar, a popular restaurant in Nice. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Le Vingt4, a hidden gem nestled in Nice. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
Round off your dining experience by visiting Trafalbar Nice, a prime location for a drink. Alternatively, explore the distinctive characteristics of Bay Side, a bar catering to every mood and preference.
Take some time to reflect on your day and savor another beautiful night in France.
Day 7
- Nice
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Drive 74 km, 1 hour 46 min
- Marché Forville
- Vieux Port de Cannes
- Palace of Festivals and Congresses of Cannes
- National Picasso Museum
- Rue d'Antibes
- La Croisette
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Wake up to day 7 of your extraordinary road trip in France. With 1 night left in Nice, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!
Set aside time today to explore Rue d'Antibes, a standout street that reflects the essence of the city. While you're there, you'll also be within reach of some of the city's top landmarks, making it easy to maximize your day. You might also want to visit La Croisette, a street offering another perspective on the town.
Today’s route brings family-friendly attractions, picturesque spots, and wallet-friendly activities. The first attraction of today is Marché Forville. This worthwhile food market is an instagrammable place to see in Nice.
As you stroll around Nice, take in the distinct atmosphere and learn what makes this town so unique. Maximize your sightseeing with a visit to Palace Of Festivals And Congresses Of Cannes. Next, make your way to National Picasso Museum to add another highlight to your day. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Nice.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Nice.
Indulge in a memorable dining experience at one of Nice's most popular restaurants, and connect with friendly locals for an authentic adventure.
Enjoy a delicious meal at Hôtel West End Nice, a highly-rated dining destination in Nice. If you're eager to try something different, consider Z Restaurant Tapas, another top spot with a tantalizing menu. You might also want to secure a reservation at Café de Nice. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Nice this evening.
Relax and reminisce about your day in France and look forward to more memorable moments to come!
Day 8
- Nice
- Lyon
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Drive 471 km, 4 hours 50 min
- Parc des Berges du Rhône
- Fontaine de Place Antonin Poncet
- Place Bellecour
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Embark on another extraordinary experience on day 8 of your road trip in France. Today, you will make 2 stops and experience some of the highlights of La Mulatière and Lyon. At the end of the day, you will enjoy the comforts of a top-rated hotel in Lyon, which will be your home away from home for 3 nights.
Nice is brimming with adventures. Today’s wonderful stops include a park and a public square. Begin your sightseeing adventure at the worthwhile Parc Des Berges Du Rhône and allow yourself time to explore. Just a short distance away you'll find your next stop, Fontaine De Place Antonin Poncet, a remarkable public square that draws visitors from far and near.
Continue your journey to Place Bellecour, one of the village’s most captivating spots that you shouldn’t miss.
At the end of the day, you will drive to Lyon, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As dinnertime approaches, it's time to head out for a bite to eat in Lyon. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Dine in style at Nuage café, a top recommendation for dinner tonight. Or, for a change of pace, Café du Rhône boasts a menu that's sure to impress. Also, be sure to check out Agastache Restaurant. Known as a local hotspot, it’s a great choice for tonight in Lyon.
Extend your evening after a delightful meal by visiting L' Antiquaire, which offers the perfect atmosphere for a night out. Moreover, Black Forest Society is another popular option for a drink or two. Likewise, Pompette also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.
Celebrate another amazing day of your road trip adventure in France!
Day 9
- Lyon
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Drive 4 km, 1 hour 3 min
- Gallo-Roman Museum of Lyon-Fourvière
- La Basilique Notre Dame de Fourvière
- Musée Cinéma et Miniature
- Lyon Cathedral
- Vieux Lyon
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On day 9 of your road trip, you will have an entire day to explore Lyon. You’ll stay in Lyon for 2 nights and discover all the best things to see and do in the area.
One of the most iconic places you can visit today in Lyon is Vieux Lyon. Allow yourself some time to explore this neighborhood and discover its unique quirks. You'll also find many of the best sightseeing spots nearby.
Prepare for a day full of family-friendly attractions, breathtaking views, and photo-friendly spots. When you’re ready, kick off your sightseeing adventure at Gallo-roman Museum Of Lyon-fourvière. This curiosity-inducing museum is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Basilica Of Notre-dame De Fourvière, one of the city’s best highlights.
Next, check out Musée Miniature Et Cinéma, one of the most increasingly popular places to see in Lyon. This museum is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Lyon Cathedral. Wander around and soak in the visually striking atmosphere this church offers.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. France is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Lyon. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Treat yourself to a delightful dinner at Bulle - Restaurant de Fourvière - Guy Lassausaie, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Bernachon Chocolats? It's another excellent option with a diverse menu. Consider reserving a table at La Mère Léa as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Lyon.
Following your dinner, dive into the local bar culture at The James Joyce Pub. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Broc'bar, the perfect place for those looking to experience the best of the nightlife. Similarly, La Passagère provides excellent drinks and a great atmosphere, ensuring a memorable night out.
As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in France.
Day 10
- Lyon
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Drive 146 km, 2 hours 22 min
- La Maison du terroir beaujolais
- Vins Georges Duboeuf SA
- parc de la Tête d'Or
- Wall of the Canuts
- La Croix-Rousse
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On day 10 of your road trip in France, you’ll start and end your day in Lyon, but spend the day exploring what’s beyond the city. Since you will return to Lyon for 1 night more, there’s no need to rush. Experience Beaujeu, La Gare, Caluire-et-Cuire, and Lyon to the fullest today with this curated day itinerary!
At the top of the list of things to do today is to explore La Croix-Rousse, a neighborhood that captures the true essence of Beaujeu. Take your time to uncover its best sides and enjoy its proximity to many of the area’s best attractions.
Lyon is home to plenty of attractions that offer family-friendly attractions, picturesque spots, and history-rich sites! Start at La Maison Du Terroir Beaujolais, a beloved visitor center that is worthwhile a visit in the village. Nearby, you’ll find Vins Georges Duboeuf Sa, enchanting visitors with its romantic appeal. Continue your exploration at Parc De La Tête D'or. This park is one of the village’s most top-rated spots.
Enjoy the freedom of exploring Lyon at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Wall Of The Canuts.
When you’re done exploring for the day, you’ll return to Lyon and your accommodation.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Lyon. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Enjoy a delicious meal at Nosch, a top-rated dining destination in Lyon. If you're in the mood to try something new, consider Auberge des canuts - Bouchon Lyonnais, another top spot with a mouthwatering menu. You might also want to secure a reservation at Vieille Canaille. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Lyon this evening.
Following your dinner, dive into the local bar culture at La Raffinerie. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Bar Le Florian, Cocktails & Spirits, the perfect place for those looking to experience the best of the nightlife. Similarly, Mos - Maker Of Stories provides excellent drinks and a great atmosphere, ensuring a memorable night out.
Raise your glass to another unforgettable day in France!
Day 11
- Lyon
- Grenoble
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Drive 315 km, 5 hours 9 min
- Route touristique de Combe Laval
- Choranche cave
- Musée départemental de la Résistance du Vercors
- La cascade monumentale
- Les maisons suspendues de Pont-en-Royans
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Experience an unparalleled adventure on day 11 of your road trip in France. This exciting part of your journey invites you to discover the renowned landmarks in 4 vibrant destinations - Die, Choranche, Vassieux-en-Vercors, and Pont-en-Royans. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Grenoble. You will spend 1 night here for some well-deserved relaxation.
Get ready to discover some of the most iconic wonders in Lyon, including a cliff, a cave, a museum, a monument, a historical landmark and much more! Start your day at Route Touristique De Combe Laval. This eye-catching cliff is an increasingly popular place to see in Lyon. Then, wander over to Choranche Cave. If majestic sites excite you, this cave will be right up your alley. Nearby, you’ll also find Musée Départemental De La Résistance Du Vercors. This standout museum is a favorite among visitors.
Lyon offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, La Cascade Monumentale is a locally appreciated spot in the region that will captivate you with its unique charm. When you’re done at the monument, don’t forget to check out the visually striking Les Maisons Suspendues De Pont-en-royans. Take a moment to appreciate the fascinating details of this often recommended historical landmark.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Grenoble. Grenoble offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Grenoble. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Treat yourself to a wonderful meal at La Bobine, a top-rated dining spot in Grenoble. If you're in the mood for something new, try Restaurant Une Semaine sur Deux, another premier location with a delectable menu. You might also want to book a table at restaurant brasserie L'Albatros Grenoble. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Grenoble.
After your delicious meal, get a taste of the vibrant nightlife with a visit to Pub Des Copains, known for its inviting atmosphere. Blind Pig is another great option if you’re looking for a place to get the night started.
As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in France.
Day 12
- Grenoble - Departure day
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- Cathédrale Notre-Dame
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Day 12 of your road trip in France is your departure day. This is your chance to catch a last glimpse of Grenoble before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, begin at Cathédrale Notre-dame. This curiosity-inducing church is a popular place to see in the city.
Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.
Before you conclude your road trip in France, drop by another restaurant for a last chance at a memorable dining experience in Grenoble.
If you're in the mood to try something new, consider Little copains, another top spot with a mouthwatering menu.
You’ll then say farewell to Grenoble. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in France!
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