12-Day France Self-Drive Road Trip With Itinerary from Lyon traveling south to Annecy, Avignon, and Nice

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Photo of summer view over Vieux Lyon, with famous cathedral Fourviere, and Croix Rousse in Lyon, France.
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Experience the freedom of the open road in France as you embark on an unforgettable 12-day road trip! This experience caters to every traveler, featuring destinations like Lyon, Caluire-et-Cuire, Annecy, Chamonix Mont Blanc, Grenoble, Avignon, Sagriès, Uzès, Gaujac, Aix-en-Provence, Nice, Monaco, and Castellane.

This perfectly planned road trip itinerary in France takes you through some of the best places to see in the country. You will spend 3 nights in Lyon, 3 nights in Annecy, 3 nights in Avignon, and 2 nights in Nice. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in France. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Lyon, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover France on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in France. Parc De La Tête D'or and Palais Des Papes are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Monte Carlo Casino, learn more about the unique Pont Du Gard, and immerse yourself in the vibrant atmosphere of Musée Océanographique De Monaco.

As you hit the open road and drive through Lyon, Caluire-et-Cuire, Annecy, Chamonix Mont Blanc, Grenoble, Avignon, Sagriès, Uzès, Gaujac, Aix-en-Provence, Nice, Monaco, and Castellane, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of France. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in France.

Throughout your road trip in France, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in France.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in France fill up quickly, so book your spot early. Select a date and start planning your road trip in France today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Place Bellecour
parc de la Tête d'OrFresque des LyonnaisMusée Cinéma et MiniatureLa Basilique Notre Dame de FourvièreLa Croix-RousseVieux Lyon
Lac d'AnnecyMusée-Château d'AnnecyJardins de l'Europe d'AnnecyPont des AmoursLe Pâquier d'Annecy
Compagnie du Mont BlancLe Pas dans le VideAiguille du Midi
Museum of GrenobleMusée dauphinoisJardin des DauphinsBastille
Pont d'AvignonPalais des PapesMusée du Petit PalaisJardin des doms

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Day 1

Day 1

  • Lyon - Arrival day
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  • Place Bellecour
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Welcome to Lyon, the perfect starting point for your road trip in France! Pick up your rental car and let the adventure begin. You will spend 2 nights immersing yourself in Lyon's charm before embarking on the next leg of your journey.

Lyon is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Place Bellecour, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Lyon. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in France. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Lyon, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Nuage café, an iconic dining spot in Lyon. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Café du Rhône, a popular restaurant in Lyon. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Agastache Restaurant, a hidden gem nestled in Lyon. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, L' Antiquaire stands out as an excellent choice for a post-dinner cocktail. Alternatively, Black Forest Society offers an ideal atmosphere to enjoy the pleasures of the night. Pompette is also a great option that provides a perfect setting for a relaxing evening.

Raise a toast to the start of your 12-day road trip in France!

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Day 2

Day 2

  • Lyon
  • More

Drive 20 km, 1 hour 18 min

  • parc de la Tête d'Or
  • Fresque des Lyonnais
  • Musée Cinéma et Miniature
  • La Basilique Notre Dame de Fourvière
  • La Croix-Rousse
  • Vieux Lyon
  • More

Wake up to day 2 of your extraordinary road trip in France. With 1 night left in Lyon, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

La Croix-Rousse is a neighborhood that stands out as one of the must-see places in Caluire-et-Cuire. Take a moment to explore its distinct atmosphere, and don’t miss the popular sightseeing spots just a short walk away. For another highlight, head to Vieux Lyon, a neighborhood offering its own unique experiences.

Today, you'll explore some of the most beautiful places in Lyon, including a park, a street art, a museum, a church and much more! Start your day with a visit to Parc De La Tête D'or. This astonishing park is a must-visit in the town. When you’re ready for your next discovery, continue to Fresque Des Lyonnais, which may be one of the most breathtaking places you will experience today.

One of the best things about exploring Lyon on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Musée Miniature Et Cinéma, a locally appreciated museum in the town. If you’re up for more discoveries, don’t forget to reserve some time for Basilica Of Notre-dame De Fourvière.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Lyon.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Lyon. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a wonderful meal at Bulle - Restaurant de Fourvière - Guy Lassausaie, a top-rated dining spot in Lyon. If you're in the mood for something new, try Bernachon Chocolats, another premier location with a delectable menu. You might also want to book a table at La Mère Léa. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Lyon.

Following your dinner, dive into the local bar culture at The James Joyce Pub. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Broc'bar, the perfect place for those looking to experience the best of the nightlife. Similarly, La Passagère provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Say good night to Lyon and look forward to another great day of your road trip in France!

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Day 3

Day 3

  • Lyon
  • Annecy
  • More

Drive 167 km, 2 hours 37 min

  • Lac d'Annecy
  • Musée-Château d'Annecy
  • Jardins de l'Europe d'Annecy
  • Pont des Amours
  • Le Pâquier d'Annecy
  • More

Embark on another extraordinary experience on day 3 of your road trip in France. Today, you will make 1 stop and experience some of the highlights of Annecy. At the end of the day, you will enjoy the comforts of a top-rated hotel in Annecy, which will be your home away from home for 3 nights.

Set out on a day brimming with family-friendly attractions, romantic experiences, and natural wonders. Start at the often recommended Lake Annecy, a mesmerizing lake in Lyon. Next, go to Musée-château D'annecy.

After visiting Lake Annecy and Musée-château D'annecy, have a stroll along Lyon's streets and take in the local charm. Continue your sightseeing by heading to Jardins De L'europe D'annecy. This noteworthy park offers a unique experience. Pont Des Amours is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Le Pâquier D'annecy, one of the most romantic places to visit in Lyon.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Annecy. Annecy offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Annecy's most popular restaurants, and connect with friendly locals for an authentic adventure.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in France.

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Day 4

Day 4

  • Annecy
  • More

Drive 215 km, 2 hours 39 min

  • Compagnie du Mont Blanc
  • Le Pas dans le Vide
  • Aiguille du Midi
  • More

On day 4 of your road trip, you’ll start and end your day in Annecy, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Chamonix Mont Blanc and Bonneville. You still have 2 nights left in Annecy.

Brace yourself for today’s incredible lineup of attractions in Annecy, featuring fun adventures, natural wonders, and breathtaking views. Start at Compagnie Du Mont Blanc, a locally renowned ski resort in the town. Then, head to Le Pas Dans Le Vide and soak in the ambiance of this visually striking observation deck.

There are many interesting places to see in Annecy, and when you are ready for more, go to Aiguille Du Midi. This is one of the town’s most locally appreciated romantic spots of interest.

When you’re done exploring for the day, you’ll return to Annecy and your accommodation.

As you explore more of Annecy, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Head back to your accommodation in Annecy and get some rest in preparation for another magical day of your road trip in France!

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Day 5

Day 5

  • Annecy
  • More

Drive 218 km, 3 hours 41 min

  • Museum of Grenoble
  • Musée dauphinois
  • Jardin des Dauphins
  • Bastille
  • More

On day 5 of your road trip in France, you’ll start and end your day in Annecy, but spend the day exploring what’s beyond the city. Since you will return to Annecy for 1 night more, there’s no need to rush. Experience Grenoble to the fullest today with this curated day itinerary!

Start by visiting Musée De Grenoble, a prime spot to begin your journey. This eye-catching museum is sure to impress. Next on your list is Musée Dauphinois, another must-visit landmark and curiosity-inducing museum renowned for its awe-inspiring features.

While exploring and sightseeing, take time to savor the culture of Annecy by sampling some local delicacies. When you’re ready for more sightseeing, head to Jardin Des Dauphins. This respected park is an essential place to visit for anyone looking for the full Annecy experience. We also recommend visiting Fort De La Bastille, an intriguing castle.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Annecy.

Indulge in a memorable dining experience at one of Annecy's most popular restaurants, and connect with friendly locals for an authentic adventure.

Relax and recharge in preparation for another adventurous day in France!

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Day 6

Day 6

  • Annecy
  • Avignon
  • More

Drive 340 km, 3 hours 41 min

  • Pont d'Avignon
  • Palais des Papes
  • Musée du Petit Palais
  • Jardin des doms
  • More

Experience an unparalleled adventure on day 6 of your road trip in France. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Avignon. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Avignon. You will spend 3 nights here for some well-deserved relaxation.

Enjoy the perfect balance of relaxation and exploration in Annecy today. One of the most popular attractions included on the itinerary is Pont Saint-benezet (le Pont D'avignon). This enchanting historical landmark will help you start your sightseeing on top. Then, take a leisurely stroll to Palais Des Papes and learn what makes this breathtaking palace unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the curiosity-inducing Musée Du Petit Palais. After exploring the museum, head to Jardin Des Doms. This curiosity-inducing park is a highlight in Annecy.

At the end of the day, you will drive to Avignon, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Avignon, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a delightful dinner at Restaurant Pollen, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Chez Bodus Le Garçon Boucher? It's another excellent option with a diverse menu. Consider reserving a table at La Cuisine de Papa as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Avignon.

Continue your lively evening at Le 17 Place Aux Vins Avignon • Bar À Vin / Caviste, a perfect place for winding down or revving up the night, depending on which mood you’re in. Barberousse Avignon is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, The Red Sky ensures a night out tailored to your taste.

Head back to your accommodation in Avignon and get some rest in preparation for another magical day of your road trip in France!

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Day 7

Day 7

  • Avignon
  • More

Drive 98 km, 2 hours 21 min

  • Pont du Gard
  • Pont du Gard Museum
  • Haribo Candy Museum
  • La vallée de l'Eure à Uzès
  • Oppidum Saint-Vincent
  • More

On day 7 of your road trip, you’ll start and end your day in Avignon, where you'll stay for 2 nights more.

Avignon is brimming with adventures. Today’s wonderful stops include a monument, a museum, a park, an archeological site and much more! Begin your sightseeing adventure at the notable Pont Du Gard and allow yourself time to explore. Just a short distance away you'll find your next stop, Pont Du Gard Museum, an UNESCO world heritage-designated museum that draws visitors from far and near.

Continue your journey to Haribo Candy Museum, one of the hamlet’s most interesting spots that you shouldn’t miss. Another great site to visit is the curiosity-inducing La Vallée De L'eure À Uzès. When you're finished at the park, Oppidum Saint-vincent awaits your visit. This archeological site is a breathtaking highlight on today's itinerary.

When you’re done exploring for the day, you’ll return to Avignon and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat in Avignon. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Le Carré du Palais, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Avenio is another top choice with a popular menu. You could also check for a table at BAR DU CHANGE. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Avignon tonight.

Extend your evening after a delightful meal by visiting O'collins's Irish Pub, which offers the perfect atmosphere for a night out. Moreover, The Gambrinus is another popular option for a drink or two.

Celebrate another amazing day of your road trip adventure in France!

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Day 8

Day 8

  • Avignon
  • More

Drive 180 km, 2 hours 55 min

  • Pavillon Vendôme
  • Paroisse Cathédrale Saint Sauveur Aix-en-Provence
  • forum des Cardeurs
  • Fontaine de la Rotonde
  • Musée Granet
  • Cours Mirabeau
  • More

At the end of the day, you'll drive back to Avignon, where you'll stay for 1 night more.

At the top of the list of things to do today is to explore Cours Mirabeau, a street that captures the true essence of Aix-en-Provence. Take your time to uncover its best sides and enjoy its proximity to many of the area’s best attractions.

Savor the day by visiting some of the best places to see in Avignon, including a museum, a church, a public square, a monument and much more! Start your adventure at Pavillon Vendôme. This intriguing museum is a must-visit for travelers looking for a unique holiday experience. Make your way to Paroisse Cathédrale Saint Sauveur Aix-en-provence located in Avignon for another exciting encounter.

Next, immerse yourself in the setting of Place Des Cardeurs. Its romantic features will captivate you. After the public square, continue your tour of the city with a visit to Fontaine De La Rotonde. Visitors usually appreciate the history-steeped features of this monument. Next up is Musée Granet, a highly recommended museum.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Avignon.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Avignon. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Bar La place ☀️ Terrasse 🍸 Cocktail 🎶 Music, a top-rated dining destination in Avignon. If you're in the mood to try something new, consider Vivotto Avignon, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ma belle cuisine. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Avignon this evening.

Raise your glass to another unforgettable day in France!

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Day 9

Day 9

  • Avignon
  • Nice
  • More

Drive 269 km, 3 hours 18 min

  • Marc Chagall National Museum
  • Castle Hill
  • place Masséna
  • Promenade du Paillon
  • More

On day 9 of your road trip in France, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Nice. In the evening, you’ll end up in Nice, where you will stay for 2 nights.

Avignon is home to plenty of attractions that offer fun adventures, romantic experiences, and natural wonders! Start at Marc Chagall National Museum, an underrated museum that is worthwhile a visit in the city. Nearby, you’ll find Castle Hill, enchanting visitors with its standout appeal. Continue your exploration at Place Masséna. This public square is one of the city’s most worthwhile spots.

Enjoy the freedom of exploring Avignon at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Promenade Du Paillon.

When you’re done exploring for the day, you’ll drive to your hotel in Nice. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Nice. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a wonderful meal at Le Bocal, a top-rated dining spot in Nice. If you're in the mood for something new, try Le Makassar, another premier location with a delectable menu. You might also want to book a table at Les Amoureux. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Nice.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Les Distilleries Idéales, known for its inviting atmosphere. Diane's is another great option if you’re looking for a place to get the night started. Similarly, Wayne's Bar provides a great setting to enjoy the night away.

Relax and reminisce about your day in France and look forward to more memorable moments to come!

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Day 10

Day 10

  • Nice
  • More

Drive 42 km, 1 hour 48 min

  • Jardin Exotique de Monaco
  • Prince's Palace of Monaco
  • Cathedral of Our Lady Immaculate
  • Musée océanographique de Monaco
  • Monte Carlo Casino
  • Monte Carlo
  • More

Greet day 10 of your road trip in France with a smile and start your day with a hearty breakfast. You will return to Nice for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Monaco.

A visit to Monte Carlo in Monaco is a must on the agenda today. This neighborhood is full of hidden gems and character, perfect for a leisurely stroll. Plus, you’ll be close to some of the city’s most famous sights.

A blend of family-friendly attractions, romantic experiences, and natural wonders await you in Nice on today’s itinerary. First up is the frequently visited botanical garden, Jardin Exotique De Monaco. Afterward, continue to Prince's Palace Of Monaco, a palace every traveler should visit.

As you explore Nice’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Cathedral Of Our Lady Immaculate. This frequently visited church is an essential stop. Following that, head to Musée Océanographique De Monaco, another must-visit site that will enhance your experience. Don’t forget to stop by Monte Carlo Casino, a locally renowned casino in the city.

When you’re done exploring for the day, you’ll return to Nice and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Nice's best restaurants.

Make sure to reserve a table at Le Windsor Jungle Art Hotel, an iconic dining spot in Nice. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Snug And Cellar, a popular restaurant in Nice. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Le Vingt4, a hidden gem nestled in Nice. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Explore the vibrant nightlife at Trafalbar Nice after your meal, a hub for lively evenings and memorable moments. Or, head to Bay Side for a great selection of flavorful drinks and a charming setting.

Relax and reminisce about your day in France and look forward to more memorable moments to come!

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Day 11

Day 11

  • Nice
  • Lyon
  • More

Drive 519 km, 7 hours 23 min

  • Pont du Roc
  • Le Roc au Serre et la chapelle Notre-Dame du Roc
  • Châteauneuf-lès-Moustiers
  • More

On day 11 of your exciting self-drive vacation in France, you’ll soak in the magnificence of 2 destinations, Castellane and Le Plan. When you’re not sightseeing, take time to relax at your selected hotel in Lyon, where you’ll be staying for 1 night.

Today, you'll explore some of the most beautiful places in Nice, including a monument, a church, and a ghost town. Start your day with a visit to Pont Du Roc. This beloved monument is a must-visit in the town. When you’re ready for your next discovery, continue to Le Roc Au Serre Et La Chapelle Notre-dame Du Roc, which may be one of the most inviting places you will experience today.

One of the best things about exploring Nice on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Châteauneuf-lès-moustiers, a beloved ghost town in the town.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Lyon. Lyon offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Lyon. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Have a fantastic dining experience at Nosch, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Auberge des canuts - Bouchon Lyonnais offers an enticing alternative with its varied menu. Additionally, Vieille Canaille is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Lyon.

Unwind after your meal by stepping into La Raffinerie. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Bar Le Florian, Cocktails & Spirits offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Mos - Maker Of Stories, another top-rated bar in the area.

Relax and recharge in preparation for another adventurous day in France!

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Day 12

Day 12

  • Lyon - Departure day
  • More
  • Porte des Enfants du Rhône
  • More

Day 12 of your road trip in France is your departure day. This is your chance to catch a last glimpse of Lyon before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Porte Des Enfants Du Rhône, a breathtaking monument before you head out.

On your last day in France, take time to indulge in shopping at Lyon’s popular marketplace, Rue de la République. Look for keepsakes or souvenirs to remind you of your trip. Browse boutiques to find unique and stylish fashion pieces.

Before you conclude your road trip in France, drop by another restaurant for a last chance at a memorable dining experience in Lyon.

If you're in the mood to try something new, consider Café Terroir, another top spot with a mouthwatering menu.

You’ll then say farewell to Lyon. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in France!

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