5-Day France Self-Drive Road Trip With Itinerary from Lyon to Avignon and Mâcon and surrounding area

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Photo of summer view over Vieux Lyon, with famous cathedral Fourviere, and Croix Rousse in Lyon, France.
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Experience the freedom of the open road on an unforgettable 5-day road trip in France! Embark on a self-drive tour that caters to every traveler, featuring destinations like Lyon, Caluire-et-Cuire, Avignon, Sagriès, Nimes, Mâcon, Vougeot, Nuits-Saint-Georges, and Beaune.

This perfectly planned road trip itinerary takes you through some of the best places to see in France. You will spend 2 nights in Lyon, 1 night in Avignon, and 1 night in Mâcon. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in France. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Lyon, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover France on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in France. Parc De La Tête D'or and Pont Du Gard are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Basilica Of Notre-dame De Fourvière, learn more about the unique Place Bellecour, and immerse yourself in the vibrant atmosphere of Jardin De La Fontaine.

As you hit the open road and drive through Lyon, Caluire-et-Cuire, Avignon, Sagriès, Nimes, Mâcon, Vougeot, Nuits-Saint-Georges, and Beaune, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of France. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in France.

Throughout your road trip in France, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in France.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in France fill up quickly, so book your spot early. Select a date and start planning your road trip in France today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
Drop-off: 10:00

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Day 1

Day 1

  • Lyon - Arrival day
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  • Place Bellecour
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Say hello to Lyon! Your exciting road trip through France is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Lyon for 1 night before you continue your adventure!

Lyon is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Place Bellecour, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Lyon. Check-in typically starts around 2 to 4 PM at hotels in France. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Lyon, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Nuage café, a top-rated dining spot in Lyon. If you're in the mood for something new, try Café du Rhône, another premier location with a delectable menu. You might also want to book a table at Agastache Restaurant. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Lyon.

Explore the vibrant nightlife at L' Antiquaire after your meal, a hub for lively evenings and memorable moments. Or, head to Black Forest Society for a great selection of flavorful drinks and a charming setting. Furthermore, Pompette is perfect for those looking to extend their night with a touch of local flavor.

Raise a toast to the start of your 5-day road trip in France!

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Day 2

Day 2

  • Lyon
  • Avignon
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Drive 250 km, 3 hours 6 min

  • Musée Cinéma et Miniature
  • Lyon Cathedral
  • La Basilique Notre Dame de Fourvière
  • parc de la Tête d'Or
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On day 2 of your road trip in France, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Lyon and Caluire-et-Cuire are on today's agenda. In the evening, you’ll end up in Avignon, where you will stay for 1 night.

Visiting Musée Miniature Et Cinéma is always a good idea. This beloved museum is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the romantic wonders of Lyon Cathedral, a must-see church in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Basilica Of Notre-dame De Fourvière. This interesting church offers an enriching experience. For a change of pace, head to Parc De La Tête D'or, where you can take in instagrammable features. These sights offer a fulfilling end to a perfect day.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Avignon. Avignon offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Avignon is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Avignon.

Make sure to reserve a table at Restaurant Pollen, an iconic dining spot in Avignon. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Chez Bodus Le Garçon Boucher, a popular restaurant in Avignon. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of La Cuisine de Papa, a hidden gem nestled in Avignon. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After savoring a delicious meal, step into the vibrant nightlife at Le 17 Place Aux Vins Avignon • Bar À Vin / Caviste, where the evening is just getting started. In the same way, Barberousse Avignon offers a unique charm perfect for experiencing the local bar scene in Avignon. The Red Sky is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Relax and look forward to more memorable moments to come!

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Day 3

Day 3

  • Avignon
  • Mâcon
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Drive 391 km, 4 hours 46 min

  • Pont du Gard
  • Haribo Candy Museum
  • Jardin de La Fontaine
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On day 3 of your exciting self-drive vacation in France, you’ll soak in the magnificence of 3 destinations, including La Bégude de Vers-Pont-du-Gard, Sagriès, and Nimes. When you’re not sightseeing, take time to relax at your chosen hotel in Mâcon, where you’ll be staying for 1 night.

Look forward to a unique sightseeing adventure at the captivating Pont Du Gard and allow yourself time to explore. Just a short distance away you'll find your next stop, Haribo Candy Museum, a picture-perfect museum that draws visitors from far and near.

Continue your journey to Jardin De La Fontaine, one of the hamlet’s most well-known spots that you shouldn’t miss.

When you’re done exploring for the day, you’ll drive to your hotel in Mâcon. Check in and relax before you head out to tour the town.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Mâcon. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Say good night to Mâcon and look forward to another great day of your road trip in France!

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Day 4

Day 4

  • Mâcon
  • Lyon
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Drive 291 km, 3 hours 29 min

  • Clos de Vougeot Castle
  • Le Cassissium
  • Park Bouzaise
  • La Moutarderie Fallot
  • Hôtel-Dieu Museum - Hospices de Beaune
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Your itinerary for day 4 of your road trip in France includes 3 stops and features some of the highlights of Vougeot, Nuits-Saint-Georges, and Beaune. At the end of the day, enjoy the comforts of a top-rated hotel in Lyon, where you'll spend 1 night.

To truly experience Mâcon, make sure to drop by Clos De Vougeot. This underrated castle is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Le Cassissium, one of the village’s best highlights.

Next, check out Park Bouzaise, one of the most often recommended places to see in Mâcon. This park is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, La Moutarderie Fallot. Wander around and soak in the respected atmosphere this museum offers. Then, head to Hôtel-dieu Museum - Hospices De Beaune, a top-rated museum that adds another dimension to your day.

At the end of the day, you will drive to Lyon, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Lyon. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a lovely dining experience at Bulle - Restaurant de Fourvière - Guy Lassausaie, a popular restaurant in Lyon. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Lyon at Bernachon Chocolats, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated La Mère Léa. It’s yet another ideal choice to enhance your time in Lyon tonight.

After your delicious meal, get a taste of the vibrant nightlife with a visit to The James Joyce Pub, known for its inviting atmosphere. Broc'bar is another great option if you’re looking for a place to get the night started. Similarly, La Passagère provides a great setting to enjoy the night away.

As the sun sets, rest up and recharge for the next leg of your road trip in France.

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Day 5

Day 5

  • Lyon - Departure day
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  • Fresque des Lyonnais
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Day 5 of your road trip in France is your departure day. This is your chance to catch a last glimpse of Lyon before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Fresque Des Lyonnais, a picture-perfect street art before you head out.

Make the most of your final day in France by visiting Lyon’s iconic markets and shopping establishments in the buzzing Part-Dieu Mall. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation.

Before you conclude your road trip in France, drop by another restaurant for a last chance at a memorable dining experience in Lyon.

Treat yourself to a delicious dinner at Nosch, an excellent option for tonight's dining. Looking for something different? Auberge des canuts - Bouchon Lyonnais offers a tantalizing alternative with its diverse menu. And don’t miss Vieille Canaille.

You’ll then say farewell to Lyon. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in France!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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