6-Day France Self-Drive Road Trip With Itinerary from Lyon to Avignon and Marseille

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Photo of summer view over Vieux Lyon, with famous cathedral Fourviere, and Croix Rousse in Lyon, France.
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Experience the freedom of the open road on an unforgettable 6-day road trip in France! Embark on a self-drive tour that caters to every traveler, featuring destinations like Lyon, Caluire-et-Cuire, Avignon, Marseille, and Cassis.

This perfectly planned road trip itinerary takes you through some of the best places to see in France. You will spend 3 nights in Lyon, 1 night in Avignon, and 1 night in Marseille. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in France. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Lyon, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover France on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in France. Parc De La Tête D'or and Notre-dame De La Garde (marseille) are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Lyon, Caluire-et-Cuire, Avignon, Marseille, and Cassis, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of France. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in France.

Throughout your road trip in France, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in France.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in France fill up quickly, so book your spot early. Select a date and start planning your road trip in France today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day1

Day 1

  • Lyon - Arrival day
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  • Place Bellecour
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Your road trip adventure in France begins as soon as you reach Lyon and pick up your car. You’ll stay here for 2 nights and explore what to see in Lyon, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Lyon is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Place Bellecour. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Lyon. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Lyon, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Nuage café, an iconic dining spot in Lyon. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Café du Rhône, a popular restaurant in Lyon. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Agastache Restaurant, a hidden gem nestled in Lyon. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Round off your dining experience by visiting L' Antiquaire, a prime location for a drink. Alternatively, explore the distinctive characteristics of Black Forest Society, a bar catering to every mood and preference. Pompette likewise offers a unique atmosphere, perfect for a memorable night out.

Raise a toast to the start of your 6-day road trip in France!

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Day2

Day 2

  • Lyon
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Drive 17 km, 1 hour 12 min

  • parc de la Tête d'Or
  • Gallo-Roman Museum of Lyon-Fourvière
  • La Basilique Notre Dame de Fourvière
  • Lyon Cathedral
  • La Croix-Rousse
  • Vieux Lyon
  • More

On day 2 of your road trip, you'll get the chance to experience Caluire-et-Cuire and Lyon. At the end of the day, you'll drive back to Lyon, where you still have 1 night left to stay.

Set aside time today to explore La Croix-Rousse, a standout neighborhood that reflects the essence of the city. While you're there, you'll also be within reach of some of the city's top landmarks, making it easy to maximize your day. You might also want to visit Vieux Lyon, a neighborhood offering another perspective on the town.

Parc De La Tête D'or brings Lyon's character to life. This stunning park is a highlight of any visit in the town. Then, enjoy Gallo-roman Museum Of Lyon-fourvière, another standout attraction that never fails to captivate visitors. Next, head over to Basilica Of Notre-dame De Fourvière, one of the town’s most interesting attractions, known for its grand features.

If you’re looking for more, spend time soaking in the atmosphere of Lyon Cathedral. This visually striking church is frequented by locals and tourists alike. To complete your memorable day, make sure to take a stroll around the area.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Lyon.

After a day of adventure, treat yourself to an exquisite dinner at one of Lyon's best restaurants.

Treat yourself to a delightful dinner at Bulle - Restaurant de Fourvière - Guy Lassausaie, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Bernachon Chocolats? It's another excellent option with a diverse menu. Consider reserving a table at La Mère Léa as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Lyon.

After your delicious meal, get a taste of the vibrant nightlife with a visit to The James Joyce Pub, known for its inviting atmosphere. Broc'bar is another great option if you’re looking for a place to get the night started. Similarly, La Passagère provides a great setting to enjoy the night away.

Relax and recharge in preparation for another adventurous day in France!

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Day3

Day 3

  • Lyon
  • Avignon
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Drive 228 km, 2 hours 52 min

  • Remparts d'Avignon
  • Palais des Papes
  • Jardin des doms
  • Musée du Petit Palais
  • More

Dive into day 3 of your remarkable road trip in France. Today you'll explore 1 destination, including Avignon. At the end of the day, you’ll unwind at one of the finest accommodations in Avignon, where you'll spend 1 night.

Remparts D'avignon is must-visit historical landmark and a great option for a daytime tour of the area. Continue your journey to Palais Des Papes, a captivating palace, located just a leisurely stroll away. Next, head to Jardin Des Doms, a romantic park, also available for your discovery today.

When you’re done exploring for the day, you’ll drive to your hotel in Avignon. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Avignon. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a fantastic dining experience at Restaurant Pollen, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Chez Bodus Le Garçon Boucher offers an enticing alternative with its varied menu. Additionally, La Cuisine de Papa is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Avignon.

Let the evening flow smoothly from dinner to drinks at Le 17 Place Aux Vins Avignon • Bar À Vin / Caviste, a top-rated bar in the area. For other recommendations, Barberousse Avignon provides a perfect setting for rounding out your night with style and great drinks. Likewise, The Red Sky offers a memorable night with diverse drink options and excellent service.

As the sun sets, rest up and recharge for the next leg of your road trip in France.

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Day4

Day 4

  • Avignon
  • Marseille
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Drive 132 km, 2 hours 31 min

  • Calanques National Park
  • Basilica of Notre-Dame of la Garde
  • Mucem - Museum of Civilizations of Europe and the Mediterranean
  • More

On day 4 of your road trip in France, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Marseille are on today's agenda. In the evening, you’ll end up in Marseille, where you will stay for 1 night.

Visiting Calanques National Park is always a good idea. This well-known national park is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the visually striking wonders of Notre-dame De La Garde (marseille), a must-see church in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Mucem - Museum Of Civilizations Of Europe And The Mediterranean. This well-known museum offers an enriching experience.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Marseille. Marseille offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Marseille's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a delightful dinner at Chez Roger, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Les Mets des Saintes? It's another excellent option with a diverse menu. Consider reserving a table at Hôtel Maison Montgrand Vieux-Port as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Marseille.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Le Traquenard stands out as an excellent choice for a post-dinner cocktail. Alternatively, La Dame Du Mont offers an ideal atmosphere to enjoy the pleasures of the night. Polikarpov is also a great option that provides a perfect setting for a relaxing evening.

Get a good night's sleep and look forward to another great day on the road in France!

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Day5

Day 5

  • Marseille
  • Lyon
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Drive 387 km, 4 hours 41 min

  • Old Port of Marseille
  • St Vincent de Paul Church
  • Calanque de Port-Miou
  • Route des crêtes
  • More

Your itinerary for day 5 of your road trip in France includes 2 stops and features some of the highlights of Marseille and Cassis. At the end of the day, enjoy the comforts of a top-rated hotel in Lyon, where you'll spend 1 night.

Check out the increasingly popular marina, Old Port Of Marseille. Afterward, continue to St. Vincent De Paul Church, a church every traveler should visit. As you explore Marseille’s charming streets, take in the lively atmosphere and get to know the character of the city.

Next, make your way to Calanque De Port-miou. This up-and-coming marina is an essential stop. Following that, head to Route Des Crêtes, another must-visit site that will enhance your experience.

At the end of the day, you will drive to Lyon, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Lyon's best restaurants.

Treat yourself to a wonderful meal at Nosch, a top-rated dining spot in Lyon. If you're in the mood for something new, try Auberge des canuts - Bouchon Lyonnais, another premier location with a delectable menu. You might also want to book a table at Vieille Canaille. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Lyon.

Explore the vibrant nightlife at La Raffinerie after your meal, a hub for lively evenings and memorable moments. Or, head to Bar Le Florian, Cocktails & Spirits for a great selection of flavorful drinks and a charming setting. Furthermore, Mos - Maker Of Stories is perfect for those looking to extend their night with a touch of local flavor.

Head back to your accommodation in Lyon and get some rest to prepare for another magical day of your road trip in France.

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Day6

Day 6

  • Lyon - Departure day
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  • Porte des Enfants du Rhône
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Day 6 of your road trip in France is your departure day. This is your chance to catch a last glimpse of Lyon before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Porte Des Enfants Du Rhône. This frequently visited monument is a hotspot among locals.

Make the most of your final day in France by visiting Lyon’s iconic markets and shopping establishments in the buzzing Part-Dieu Mall. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation.

Before you conclude your road trip in France, drop by another restaurant for a last chance at a memorable dining experience in Lyon.

If you're eager to try something different, consider Café Terroir, another top spot with a tantalizing menu.

You’ll then say farewell to Lyon. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in France!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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