6-Day Germany Self-Drive Road Trip With Itinerary from Karlsruhe traveling north to Stuttgart, Frankfurt, and Cologne

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Photo of old Hygieia Fountain in Karlsruhe.
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Explore the best of Germany on a remarkable 6-day road trip! Combine exploration with relaxation on a self-drive tour featuring Karlsruhe, Stuttgart, Heidelberg, Frankfurt, Brühl, Cologne, and Speyer.

This perfectly planned road trip itinerary takes you through some of the best places to see in Germany. You will spend 2 nights in Karlsruhe, 1 night in Stuttgart, 1 night in Frankfurt, and 1 night in Cologne. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Germany. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Karlsruhe, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Germany on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Germany. Phantasialand and Cologne Cathedral are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Heidelberg Castle, learn more about the unique Mercedes-benz Museum, and immerse yourself in the vibrant atmosphere of Schloßplatz.

As you hit the open road and drive through Karlsruhe, Stuttgart, Heidelberg, Frankfurt, Brühl, Cologne, and Speyer, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Germany. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Germany.

Throughout your road trip in Germany, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Germany.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Germany fill up quickly, so book your spot early. Select a date and start planning your road trip in Germany today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day 1

Day 1

  • Karlsruhe - Arrival day
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  • Kaiserstraße
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Your road trip adventure in Germany begins as soon as you reach Karlsruhe and pick up your car. You’ll stay here for 1 night and explore what to see in Karlsruhe, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Karlsruhe is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Kaiserstraße, a must-see street, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Karlsruhe. Check-in typically starts around 2 to 4 PM at hotels in Germany. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Karlsruhe, it's often a good idea to reserve a table in advance.

Dine in style at Hotel Rio Karlsruhe, a top recommendation for dinner tonight. Or, for a change of pace, Zum Kleinen Ketterer boasts a menu that's sure to impress. Also, be sure to check out Seng Sushi & Chinarestaurant. Known as a local hotspot, it’s a great choice for tonight in Karlsruhe.

After savoring a delicious meal, step into the vibrant nightlife at Phono Craftbeer Bar, where the evening is just getting started. In the same way, Electric Eel offers a unique charm perfect for experiencing the local bar scene in Karlsruhe. Jean-claude Cocktail Bar is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise a toast to the start of your 6-day road trip in Germany!

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Day 2

Day 2

  • Karlsruhe
  • Stuttgart
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Drive 81 km, 1 hour 56 min

  • State Museum of Natural History, Karlsruhe
  • Schlossgarten
  • ZKM Center for Art and Media Karlsruhe
  • Zoological Gardens Karlsruhe
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Your itinerary for day 2 of your road trip in Germany includes 1 stop and features some of the highlights of Karlsruhe. At the end of the day, enjoy the comforts of a top-rated hotel in Stuttgart, where you'll spend 1 night.

Awaiting your discovery is the beloved State Museum Of Natural History, Karlsruhe, an instagrammable museum in Karlsruhe. Next, go to Schlossgarten.

Zoological Gardens Karlsruhe is another noteworthy attraction worthwhile a visit.

When you’re done exploring for the day, you’ll drive to your hotel in Stuttgart. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Stuttgart's best restaurants.

Enjoy an outstanding dining experience at Der Zauberlehrling, a 1-star Michelin restaurant offering an exceptional creative menu. Alternatively, if you're in the mood for something different, consider the nearby 2-star Michelin-awardee, Speisemeisterei, known for its delicious creative and innovative cuisine. Another highly-recommended place to eat in Stuttgart is Ritzi Gourmet, a renowned restaurant with a 1-star Guide Michelin recognition and a delicious creative french and modern menu.

After savoring a delicious meal, step into the vibrant nightlife at Le Petit Coq, where the evening is just getting started. In the same way, Jigger & Spoon offers a unique charm perfect for experiencing the local bar scene in Stuttgart. Schwarz Weiß Bar is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Take some time to reflect on your day and savor another beautiful night in Germany.

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Day 3

Day 3

  • Stuttgart
  • Frankfurt
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Drive 223 km, 3 hours 19 min

  • Schlossplatz
  • Mercedes-Benz Museum
  • Heidelberg Palace
  • Old Bridge Heidelberg
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On day 3 of your exciting self-drive vacation in Germany, you’ll soak in the magnificence of 2 destinations, including Stuttgart and Heidelberg. When you’re not sightseeing, take time to relax at your chosen hotel in Frankfurt, where you’ll be staying for 1 night.

Look forward to a unique sightseeing adventure at the popular Schloßplatz and allow yourself time to explore. Just a short distance away you'll find your next stop, Mercedes-benz Museum, an awe-inspiring museum that draws visitors from far and near.

Continue your journey to Heidelberg Castle, one of the city’s most extraordinary spots that you shouldn’t miss. Another great site to visit is the well-known Old Bridge Heidelberg.

At the end of the day, you will drive to Frankfurt, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Frankfurt. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a memorable dining experience in Frankfurt by booking a table at Gustav, a 2-star Michelin restaurant presenting an exceptional creative menu. For a different culinary experience in Frankfurt, Lafleur shines as one of the top destinations, known for its delicious modern french and creative cuisine. This 2-star Michelin-awardee consistently earns high praises, making it a must-visit addition to your holiday experience. If you're looking for an alternative, Erno's Bistro is known as a top local spot in Frankfurt for its delicious classic french and modern cuisine. This 1-star Michelin awardee is a highly recommended choice for an unforgettable meal.

If you’re not ready to end the night just yet, Gute Stute offers a perfect venue to relax and savor a drink. Similarly, Flemings Hotel Frankfurt-central (former Flemings Express Frankfurt) is well-suited for those looking to unwind in a social setting. Gleis 25 is another excellent spot to enjoy a nightcap after a delightful meal.

Savor another day of unforgettable experiences in Germany!

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Day 4

Day 4

  • Frankfurt
  • Cologne
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Drive 228 km, 2 hours 54 min

  • Römerberg
  • Iron Footbridge
  • Palmengarten Frankfurt
  • Phantasialand
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Dive into day 4 of your remarkable road trip in Germany. Today you'll explore 2 destinations, including Frankfurt and Brühl. At the end of the day, you’ll unwind at one of the finest accommodations in Cologne, where you'll spend 1 night.

Make a stop at Römerberg. This popular public square is a must-visit for travelers looking for a unique holiday experience. Make your way to Iron Footbridge located in Frankfurt for another exciting encounter.

Next, immerse yourself in the setting of Palmengarten. Its majestic features will captivate you. After the botanical garden, continue your tour of the city with a visit to Phantasialand. Visitors usually appreciate the instagrammable features of this amusement park.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Cologne. Cologne offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Cologne, it's often a good idea to reserve a table in advance.

Dive into a culinary adventure like no other in Cologne by booking a table at Le Moissonnier Bistro. This popular restaurant holds 1 Michelin star and offers an exceptional menu of french and seafood cuisine. For another dining option, venture to Ox & Klee, celebrated for its delectable modern and creative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, ensuring an essential addition to your holiday itinerary. Seeking an alternative? Discover La Cuisine Rademacher, a top local restaurant known for its tantalizing modern french menu. With a 1-star Michelin recognition, it promises an exceptional dining experience not to be missed.

Explore the vibrant nightlife at The Grid Bar after your meal, a hub for lively evenings and memorable moments. Or, head to Toddy Tapper for a great selection of flavorful drinks and a charming setting. Furthermore, Legends Bar & Terrasse is perfect for those looking to extend their night with a touch of local flavor.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Germany.

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Day 5

Day 5

  • Cologne
  • Karlsruhe
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Drive 323 km, 3 hours 42 min

  • Cologne Cathedral
  • Technic Museum Speyer
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Experience an unparalleled adventure on day 5 of your road trip in Germany. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Cologne and Speyer. At the end of the day, you will retreat to the hotel of your choice in Karlsruhe, where will spend 1 night.

Cologne Cathedral is an ideal stop early in the day. This famous church is a must-visit in the city. When you’re ready for your next discovery, continue to Technik Museum Speyer, which may be one of the most historic places you will experience today.

When you’re done exploring for the day, you’ll drive to your hotel in Karlsruhe. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Karlsruhe's most popular restaurants, and connect with friendly locals for a true cultural experience.

Set out on a gastronomic journey in Karlsruhe by reserving a table at Bistro Margarete. Renowned for its Bib Gourmand award, this restaurant presents an outstanding menu of regional cuisine. For a different taste, head over to sein, renowned for its delectable modern dishes. This distinguished 2-star Michelin-recipient is a favorite among guests, making it a worthy addition to your holiday plans. Craving more culinary excitement? Explore TAWA YAMA FINE, a highly rated local gem known for its exquisite modern and international menu. With a 1-star Michelin acclaim, it promises a dining experience you won't want to miss. Known for great service, it’s a fantastic choice for tonight in Karlsruhe.

Extend your evening after a delightful meal by visiting Carlos Cocktailbar, which offers the perfect atmosphere for a night out. Moreover, Ubu is another popular option for a drink or two. Likewise, Der Kofferraum - Cocktailbar also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Relax and look forward to more memorable moments to come!

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Day 6

Day 6

  • Karlsruhe - Departure day
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  • Marktplatz
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Day 6 of your road trip in Germany is your departure day. This is your chance to catch a last glimpse of Karlsruhe before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Marktplatz, a historic public square before you head out.

For a last-minute shopping spree in Karlsruhe, Postgalerie Karlsruhe is nearby. Enjoy a variety of retail stores, dining options, and essential services in one convenient location.

Before you conclude your road trip in Germany, drop by another restaurant for a last chance at a memorable dining experience in Karlsruhe.

Treat yourself to a delightful dinner at Kaiseki Japan Restaurant Karlsruhe, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try L'Osteria Karlsruhe? It's another excellent option with a diverse menu.

You’ll then say farewell to Karlsruhe. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Germany!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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