10-Day Greece Self-Drive Road Trip With Itinerary from Ioannina traveling south to Patras, Athens, Chalkida, and Larissa

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Experience the freedom of the open road in Greece as you embark on an unforgettable 10-day road trip! This experience caters to every traveler, featuring destinations like Ioannina, Perama, Neo Bizani, Patras, Antirio, Mesolongi, Kallithea, Athens, Mykines, Chalkida, Thermopyles, Larissa, Trikala, and Kastraki.

This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 2 nights in Ioannina, 1 night in Patras, 4 nights in Athens, 1 night in Chalkida, and 1 night in Larissa. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Ioannina, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. Acropolis Of Athens and Parthenon are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Acropolis Museum, learn more about the unique Stavros Niarchos Foundation Cultural Center, and immerse yourself in the vibrant atmosphere of Meteora.

As you hit the open road and drive through Ioannina, Perama, Neo Bizani, Patras, Antirio, Mesolongi, Kallithea, Athens, Mykines, Chalkida, Thermopyles, Larissa, Trikala, and Kastraki, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Ioannina Castle
The Clock Tower of IoanninaLitharitsia parkIch Kale Acropolis of IoanninaCave of PeramaVrellis Greek History Museum (Wax Museum)
Rion-Antirion BridgeGarden of HeroesWater SquareStavros Niarchos Foundation Cultural CenterStavros Niarchos Park
Archeological Museum of MycenaeMycenaeTreasury of Atreus" or "Tomb of Agamemnon
Temple of Olympian ZeusAcropolis MuseumOdeon of Herodes AtticusAcropolis of AthensParthenon
Philopappos HillMonastiraki SquareAncient Agora of AthensAdrianou StreetMonastiraki

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Day 1

Day 1

  • Ioannina - Arrival day
  • More
  • Ioannina Castle
  • More

Say hello to Ioannina! Your exciting road trip through Greece is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Ioannina for 1 night before you continue your adventure!

Ioannina is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ioannina Castle, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Ioannina. Check-in typically starts around 2 to 4 PM at hotels in Greece. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ioannina, it's often a good idea to reserve a table in advance.

Savor the flavors at To Dodeka Cafe Bar, a top pick for dinner tonight. Alternatively, Mustagogia beckons with its unique menu offerings. Also, consider Accademia Del Panino. With its consistent customer satisfaction, it’s an excellent option for dining in Ioannina tonight.

Let the evening flow smoothly from dinner to drinks at ⚜ V E D E M A ⚜, a top-rated bar in the area. For other recommendations, Hogwarts Tales And Spirits provides a perfect setting for rounding out your night with style and great drinks. Likewise, Chevalier offers a memorable night with diverse drink options and excellent service.

Raise a toast to the start of your 10-day road trip in Greece!

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Day 2

Day 2

  • Ioannina
  • Patras
  • More

Drive 235 km, 3 hours 24 min

  • The Clock Tower of Ioannina
  • Litharitsia park
  • Ich Kale Acropolis of Ioannina
  • Cave of Perama
  • Vrellis Greek History Museum (Wax Museum)
  • More

On day 2 of your road trip in Greece, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Ioannina, Perama, and Neo Bizani. In the evening, you’ll end up in Patras, where you will stay for 1 night.

Get ready for an exciting day in Ioannina. Today’s sightseeing agenda includes a monument, a park, an archeological site, a cave, a museum and much more! Begin your adventure at The Clock Tower Of Ioannina. This is a locally appreciated monument you should not miss. Another must-see is Litharitsia Park, a frequently visited park in Ioannina.

When you’re ready for the next sight, head to Ic Kale Acropolis Of Ioannina. From there, take a leisurely stroll to Cave Of Perama, another of the city’s often recommended attractions. We recommend continuing your self-guided tour at Moyseio Ellinikis Istorias Payloy Vrelli, a history-steeped place of interest in the city.

When you’re done exploring for the day, you’ll drive to your hotel in Patras. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Patras. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delicious dinner at Tag, an excellent option for tonight's dining. Looking for something different? Bianco offers a tantalizing alternative with its diverse menu. And don’t miss Carousello. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Patras.

Round off your dining experience by visiting Sofita, a prime location for a drink. Alternatively, explore the distinctive characteristics of Charama Therino, a bar catering to every mood and preference. Notos likewise offers a unique atmosphere, perfect for a memorable night out.

Get a good night's sleep and look forward to another great day on the road in Greece!

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Day 3

Day 3

  • Patras
  • Athens
  • More

Drive 301 km, 4 hours 1 min

  • Rion-Antirion Bridge
  • Garden of Heroes
  • Water Square
  • Stavros Niarchos Foundation Cultural Center
  • Stavros Niarchos Park
  • More

Embark on another extraordinary experience on day 3 of your road trip in Greece. Today, you will make 3 stops and experience some of the highlights of Antirio, Mesolongi, and Kallithea. At the end of the day, you will enjoy the comforts of a top-rated hotel in Athens, which will be your home away from home for 4 nights.

Set out on a day brimming with fun adventures, scenic views, and photo-friendly spots. Start at the increasingly popular Charilaos Trikoupis Rio - Antirrio Bridge, a culturally significant monument in Patras. Next, go to Garden Of Heroes.

Stavros Niarchos Foundation Cultural Center is another noteworthy stop. End your self-guided sightseeing tour on top with a visit to Stavros Niarchos Park, one of the most awe-inspiring places to visit in Patras.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Athens. Athens offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Athens's most popular restaurants, and connect with friendly locals for an authentic adventure.

Discover the culinary delights of Athens by securing a reservation at Hytra. Esteemed for its 1-star Guide Michelin recognition, this restaurant offers a remarkable selection of modern cuisine. For an alternative dining experience, try Spondi, renowned for its delicious french dishes. This esteemed 1-star Michelin-recipient consistently impresses guests, making it a must-visit spot during your holiday. Craving more culinary excitement? Head to The Zillers, a highly recommended local eatery celebrated for its mouthwatering contemporary and greek menu. With its 1-star Michelin recognition, it offers an unforgettable dining adventure.

Keep the evening going at Mayros Gatos, a great choice for enjoying the after-dinner hours with a drink. You could also go to Kuko's The Bar, which offers a similarly pleasant setting and great drinks. Another option is Revolt Street Bar, which provides an inviting environment for unwinding after a busy day out.

Raise your glass and celebrate another amazing day of your road trip in Greece!

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Day 4

Day 4

  • Athens
  • More

Drive 237 km, 3 hours 22 min

  • Archeological Museum of Mycenae
  • Mycenae
  • Treasury of Atreus" or "Tomb of Agamemnon
  • More

Wake up to day 4 of your extraordinary road trip in Greece. With 3 nights left in Athens, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

A blend of fun adventures, breathtaking views, and picturesque spots await you in Athens on today’s itinerary. First up is the curiosity-inducing museum, Archeological Museum Of Mycenae. Afterward, continue to Mycenae, an archeological site every traveler should visit.

As you explore Athens’s charming streets, take in the lively atmosphere and get to know the character of the village. Next, make your way to "treasury Of Atreus" Or "tomb Of Agamemnon". This underrated archeological site is an essential stop.

When you’re done exploring for the day, you’ll return to Athens and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Athens. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a lovely dining experience at Harvest Coffee & Wine, a popular restaurant in Athens. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Athens at 42 Barstronomy Athens, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated O Babas. It’s yet another ideal choice to enhance your time in Athens tonight.

Unwind after your meal by stepping into Tiki Bar Athens. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Brettos offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Luxus Bar Bistro, another top-rated bar in the area.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Greece.

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Day 5

Day 5

  • Athens
  • More

Drive 6 km, 45 min

  • Temple of Olympian Zeus
  • Acropolis Museum
  • Odeon of Herodes Atticus
  • Acropolis of Athens
  • Parthenon
  • More

Day 5 of your road trip will take you to the best attractions Athens has to offer. Cherish the 2 nights you have left in Athens by discovering the best things there are to see and do in the city.

Get ready for a day filled with family-friendly attractions, scenic views, and photo-friendly spots in the charming city of Athens. Your adventure starts at Temple Of Olympian Zeus, a locally renowned local hot spot. Another notable attraction to explore is Acropolis Museum. This impressive museum is known for its historic appeal.

After soaking in the highlights of these sights, take some time to wander Athens's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Odeon Of Herodes Atticus. This enchanting archeological site offers a fascinating experience that many visitors find memorable. Acropolis Of Athens is also worth visiting, along with Parthenon. These standout landmarks offer unique experiences that add to the day’s enjoyment.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Greece is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Athens's best restaurants.

Treat yourself to a delightful dinner at Cookoovaya, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Karamanlidika? It's another excellent option with a diverse menu. Consider reserving a table at Estiatorio Auli as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Athens.

Explore the vibrant nightlife at Kazu Cafe-bar after your meal, a hub for lively evenings and memorable moments. Or, head to Upupa Epops - The Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Gazarte is perfect for those looking to extend their night with a touch of local flavor.

Take some time to reflect on your day and savor another beautiful night in Greece.

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Day 6

Day 6

  • Athens
  • More

Drive 7 km, 46 min

  • Philopappos Hill
  • Monastiraki Square
  • Ancient Agora of Athens
  • Adrianou Street
  • Monastiraki
  • More

Day 6 of your road trip across Greece promises a magnificent time exploring Athens. You have 1 night left in Athens. Take the opportunity to experience more of the best attractions and activities in the city.

A visit to Adrianou Street in Athens is a must on the agenda today. This street is full of hidden gems and character, perfect for a leisurely stroll. Plus, you’ll be close to some of the city’s most famous sights. Don’t forget to check out Monastiraki as well, a neighborhood that adds another layer to your exploration.

Immerse yourself in Athens’s rich culture with today's sightseeing itinerary. Start your journey at Philopappos Hill. This romantic park is sure to ignite your curiosity. Next, dive into the heritage-rich features of Monastiraki Square 6, a must-visit public square in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Ancient Agora Of Athens, a locally renowned archeological site.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Greece is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Athens. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a wonderful meal at Beer Tales, a top-rated dining spot in Athens. If you're in the mood for something new, try Oinomageireio Epirus (est.1898), another premier location with a delectable menu. You might also want to book a table at To Kafeneio. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Athens.

To truly maximize your evening out, consider visiting Ipitou The Bar after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Lot 51, another bar with an inviting ambiance. Similarly, Klōstḗrion also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Get a good night's sleep and look forward to another great day on the road in Greece!

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Day 7

Day 7

  • Athens
  • Chalkida
  • More

Drive 87 km, 1 hour 35 min

  • National Archaeological Museum of Athens
  • Athens National Garden
  • Technopolis City of Athens
  • More

Dive into day 7 of your remarkable road trip in Greece. Today you will explore Athens, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Chalkida. You’ll stay here for 1 night.

Today, you'll explore some of the most beautiful places in Athens, including a museum, a botanical garden, and a cultural center. Start your day with a visit to National Archaeological Museum Of Athens. This locally renowned museum is a must-visit in the city. When you’re ready for your next discovery, continue to National Garden Of Athens, which may be one of the most awe-inspiring places you will experience today.

One of the best things about exploring Athens on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Technopolis City Of Athens, a notable cultural center in the city.

At the end of the day, you will drive to Chalkida, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Chalkida's best restaurants.

Make sure to reserve a table at Stavento, an iconic dining spot in Chalkida. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of 25 DRAMIA, a popular restaurant in Chalkida. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Psistaria Apostoloy, a hidden gem nestled in Chalkida. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Boheme Cafe Bar, a well-loved spot among locals and tourists. Or, head to Galatiko Chorio. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Euan, another top-rated place in the area.

Raise your glass to another unforgettable day in Greece!

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Day 8

Day 8

  • Chalkida
  • Larissa
  • More

Drive 301 km, 3 hours 34 min

  • Waterfront of Chalkida
  • Karababa Castle
  • Memorial of Leonidas and 300 Spartans
  • More

Experience an unparalleled adventure on day 8 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Chalkida and Thermopyles. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Larissa. You will spend 1 night here for some well-deserved relaxation.

A blend of fun adventures, romantic experiences, and scenic views await you in Chalkida on today’s itinerary. First up is the curiosity-inducing boardwalk, Chalkida's Seaside. Afterward, continue to Karababa Castle, a castle every traveler should visit.

As you explore Chalkida’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Memorial To Leonidas And 300 Spartans. This beloved war memorial is an essential stop.

When you’re done exploring for the day, you’ll drive to your hotel in Larissa. Check in and spend some time relaxing before you head out to tour the city.

As you explore more of Larissa, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at Nonna Rossa, a highly-rated dining destination in Larissa. If you're eager to try something different, consider Vosporos | Restaurant • Bar, another top spot with a tantalizing menu. You might also want to secure a reservation at THE ALLEY. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Larissa this evening.

If you’re not ready to end the night just yet, Sherlock Easy Bar offers a perfect venue to relax and savor a drink. Similarly, Kiou is well-suited for those looking to unwind in a social setting. Wisedog is another excellent spot to enjoy a nightcap after a delightful meal.

Celebrate another amazing day of your road trip adventure in Greece!

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Day 9

Day 9

  • Larissa
  • Ioannina
  • More

Drive 199 km, 4 hours 20 min

  • Trikala City Center Square
  • Matsopoulos Park
  • Meteora
  • Monastery of Varlaam
  • More

On day 9 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 2 destinations, Trikala and Kastraki. When you’re not sightseeing, take time to relax at your selected hotel in Ioannina, where you’ll be staying for 1 night.

Get ready to discover some of the most iconic wonders in Larissa, including a public square, a park, and a monastery. Start your day at Trikala City Center Square. This instagrammable public square is an intriguing place to see in Larissa. Then, wander over to Matsopoulos Park. If majestic sites excite you, this park will be right up your alley. Nearby, you’ll also find Meteora. This enchanting monastery is a favorite among visitors.

Larissa offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Monastery Of Varlaam is a beloved spot in the city that will captivate you with its unique charm.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Ioannina. Ioannina offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Ioannina. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Spitaki me thea, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Frontzoy Politeia - Frontzu Politia Restaurant is another top choice with a popular menu. You could also check for a table at Papi Cafe Bistro. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Ioannina tonight.

Cap off your dinner by heading to Scala, ideal for a leisurely evening with a drink in hand. Route 66 Bar is another bar that offers an enjoyable setting. Similarly, Palia Agora is also a popular place to go on a night out, perfect for relaxing and socializing.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Greece.

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Day 10

Day 10

  • Ioannina - Departure day
  • More
  • Kaloutsiani Mosque
  • More

Day 10 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Ioannina before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Kaloutsiani Mosque. This curiosity-inducing mosque is a popular place to see in the city.

Maximize your last day in Greece and go on a shopping spree in Ioannina’s shopping center, the lively Epirus Street. Browse for souvenirs to remind you of your wonderful journey in Greece. Discover boutiques with stylish fashion choices to upgrade your wardrobe. Take one last moment to soak in Greece, and unwind with tea or coffee at a cozy cafe.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Ioannina.

If you're eager to try something different, consider Frontzu Politia - Hotel, another top spot with a tantalizing menu.

You’ll then say farewell to Ioannina. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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