10-Day Greece Self-Drive Road Trip With Itinerary from Ioannina traveling south to Patras, Athens, Chalkida, and Larissa

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Photo of Ioannina lake Pamvotida in Epirus Region, Greece.
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Escape the ordinary with this exciting 10-day road trip through Greece. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Greece. You will spend 2 nights in Ioannina, 1 night in Patras, 4 nights in Athens, 1 night in Chalkida, and 1 night in Larissa. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Ioannina, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. Acropolis Of Athens and Parthenon are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Acropolis Museum, learn more about the unique Stavros Niarchos Foundation Cultural Center, and immerse yourself in the vibrant atmosphere of Meteora.

As you hit the open road and drive through Ioannina, Perama, Neo Bizani, Patras, Antirio, Mesolongi, Kallithea, Athens, Mykines, Chalkida, Thermopyles, Larissa, Trikala, and Kastraki, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day 1

Day 1

  • Ioannina - Arrival day
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  • Ioannina Castle
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Your road trip adventure in Greece begins as soon as you reach Ioannina and pick up your car. You’ll stay here for 1 night and explore what to see in Ioannina, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Ioannina is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ioannina Castle, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Ioannina. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Greece. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ioannina, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at To Dodeka Cafe Bar, an iconic dining spot in Ioannina. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Mustagogia, a popular restaurant in Ioannina. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Accademia Del Panino, a hidden gem nestled in Ioannina. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Round off your dining experience by visiting ⚜ V E D E M A ⚜, a prime location for a drink. Alternatively, explore the distinctive characteristics of Hogwarts Tales And Spirits, a bar catering to every mood and preference. Chevalier likewise offers a unique atmosphere, perfect for a memorable night out.

Raise a toast to the start of your 10-day road trip in Greece!

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Day 2

Day 2

  • Ioannina
  • Patras
  • More

Drive 235 km, 3 hours 24 min

  • The Clock Tower of Ioannina
  • Litharitsia park
  • Ich Kale Acropolis of Ioannina
  • Cave of Perama
  • Vrellis Greek History Museum (Wax Museum)
  • More

Your itinerary for day 2 of your road trip in Greece includes 3 stops and features some of the highlights of Ioannina, Perama, and Neo Bizani. At the end of the day, enjoy the comforts of a top-rated hotel in Patras, where you'll spend 1 night.

Let The Clock Tower Of Ioannina set the tone for the day. Spend some time admiring this culturally significant monument before continuing your journey. Litharitsia Park is your next stop. This often recommended park is one of the best-rated sights in Ioannina.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Ic Kale Acropolis Of Ioannina. This picture-perfect archeological site is a sight to behold. To round off your sightseeing experience, visit Cave Of Perama and Moyseio Ellinikis Istorias Payloy Vrelli.

When you’re done exploring for the day, you’ll drive to your hotel in Patras. Check in and relax before you head out to tour the city.

Patras is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Patras.

Treat yourself to a wonderful meal at Tag, a top-rated dining spot in Patras. If you're in the mood for something new, try Bianco, another premier location with a delectable menu. You might also want to book a table at Carousello. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Patras.

Continue your lively evening at Sofita, a perfect place for winding down or revving up the night, depending on which mood you’re in. Charama Therino is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Notos ensures a night out tailored to your taste.

As the sun sets, rest up and recharge for the next leg of your road trip in Greece.

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Day 3

Day 3

  • Patras
  • Athens
  • More

Drive 301 km, 4 hours 1 min

  • Rion-Antirion Bridge
  • Garden of Heroes
  • Water Square
  • Stavros Niarchos Foundation Cultural Center
  • Stavros Niarchos Park
  • More

On day 3 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 3 destinations, including Antirio, Mesolongi, and Kallithea. When you’re not sightseeing, take time to relax at your chosen hotel in Athens, where you’ll be staying for 4 nights.

Charilaos Trikoupis Rio - Antirrio Bridge is perfect for a self-paced visit during the day. This symbolic monument is sure to impress. Next on your list is Garden Of Heroes, another must-visit landmark and often recommended cemetery renowned for its historic features.

We also recommend visiting Stavros Niarchos Foundation Cultural Center, a famous cultural center. Nearby, you'll also find Stavros Niarchos Park, ready to add charm to your journey.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Athens. Athens offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Athens's best restaurants.

Begin your culinary exploration in Athens by securing a reservation at Hytra. This renowned restaurant holds 1 Michelin star and offers an exceptional menu of modern cuisine. For another dining delight, visit Spondi, celebrated for its delectable french menu. This acclaimed 1-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover The Zillers, a top local spot known for its tantalizing contemporary and greek menu. With a 1-star Michelin recognition, it guarantees an exceptional dining adventure.

After your meal, keep the night alive at a bar like Mayros Gatos, known for its lively atmosphere. Kuko's The Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Revolt Street Bar offers an excellent atmosphere for those looking to amp up the evening.

Head back to your accommodation in Athens and get some rest to prepare for another magical day of your road trip in Greece.

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Day 4

Day 4

  • Athens
  • More

Drive 237 km, 3 hours 22 min

  • Archeological Museum of Mycenae
  • Mycenae
  • Treasury of Atreus" or "Tomb of Agamemnon
  • More

Wake up to day 4 of your road trip in Greece. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Mykines. With 3 nights to stay in Athens, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Archeological Museum Of Mycenae makes a great addition to your morning plans. This underrated museum is an awe-inspiring place to see in Athens. Continue your discovery at Mycenae, a culturally significant archeological site with stories to tell.

As you stroll around Athens, take in the distinct atmosphere and learn what makes this village so unique. Maximize your sightseeing with a visit to "treasury Of Atreus" Or "tomb Of Agamemnon". This intriguing archeological site offers a heritage-rich encounter with Athens. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Athens.

When you’re done exploring for the day, you’ll return to Athens and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Athens. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a delicious dinner at Harvest Coffee & Wine, an excellent option for tonight's dining. Looking for something different? 42 Barstronomy Athens offers a tantalizing alternative with its diverse menu. And don’t miss O Babas. Known for great service, it’s a fantastic choice for tonight in Athens.

Keep the excitement of the evening going by visiting a bar or two. Tiki Bar Athens is an excellent place to start. You could also check out Brettos, offering a different kind of charm. A last recommendation for the day is Luxus Bar Bistro. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

As the sun sets, rest up and recharge for the next leg of your road trip in Greece.

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Day 5

Day 5

  • Athens
  • More

Drive 6 km, 45 min

  • Temple of Olympian Zeus
  • Acropolis Museum
  • Odeon of Herodes Atticus
  • Acropolis of Athens
  • Parthenon
  • More

Day 5 of your road trip across Greece promises a magnificent time exploring what to see in Athens. You have 2 nights left in Athens. Take the opportunity to experience more of the best attractions and activities in the city.

Athens is brimming with adventures.

Whatever your travel style is, Temple Of Olympian Zeus is an essential stop in Athens. This well-known archeological site provides an insightful glimpse into the city's identity. Next, discover Acropolis Museum, a historic museum, promising a delightful encounter.

Continue your sightseeing with a visit to Odeon Of Herodes Atticus, a captivating archeological site. When you’re done, don’t forget to make a stop at the globally renowned Acropolis Of Athens. Round off your day at Parthenon, another gem in Athens with historic features to discover.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Greece. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Athens's most popular restaurants, and connect with friendly locals for a true cultural experience.

Dine in style at Cookoovaya, a top recommendation for dinner tonight. Or, for a change of pace, Karamanlidika boasts a menu that's sure to impress. Also, be sure to check out Estiatorio Auli. Known as a local hotspot, it’s a great choice for tonight in Athens.

Following your dinner, dive into the local bar culture at Kazu Cafe-bar. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Upupa Epops - The Bar, the perfect place for those looking to experience the best of the nightlife. Similarly, Gazarte provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Relax and look forward to more memorable moments to come!

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Day 6

Day 6

  • Athens
  • More

Drive 7 km, 46 min

  • Philopappos Hill
  • Monastiraki Square
  • Ancient Agora of Athens
  • Adrianou Street
  • Monastiraki
  • More

Day 6 offers an itinerary packed with the best things to see in Athens. You’ll stay in Athens for 1 night more, offering you enough time to explore at a relaxed pace.

Don’t miss Adrianou Street today, a must-see street that offers a glimpse into the city’s vibrant character. Take your time to explore its best features, and enjoy the convenience of nearby top-rated landmarks. While you’re in the area, consider visiting Monastiraki, another neighborhood that adds to the charm of Athens.

Awaiting your discovery is the captivating Philopappos Hill, a standout park in Athens. Next, go to Monastiraki Square 6.

After visiting Philopappos Hill and Monastiraki Square 6, have a stroll along Athens's streets and take in the local charm. Continue your sightseeing by heading to Ancient Agora Of Athens. This standout archeological site offers a unique experience.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Greece. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Athens's best restaurants.

Make sure to reserve a table at Beer Tales, an iconic dining spot in Athens. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Oinomageireio Epirus (est.1898), a popular restaurant in Athens. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of To Kafeneio, a hidden gem nestled in Athens. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue your lively evening at Ipitou The Bar, a perfect place for winding down or revving up the night, depending on which mood you’re in. Lot 51 is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Klōstḗrion ensures a night out tailored to your taste.

As the sun sets, rest up and recharge for the next leg of your road trip in Greece.

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Day 7

Day 7

  • Athens
  • Chalkida
  • More

Drive 87 km, 1 hour 35 min

  • National Archaeological Museum of Athens
  • Athens National Garden
  • Technopolis City of Athens
  • More

Experience an unparalleled adventure on day 7 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Athens. At the end of the day, you will retreat to the hotel of your choice in Chalkida, where will spend 1 night.

Catch National Archaeological Museum Of Athens before the crowds roll in. This respected museum is sure to ignite your curiosity. Next, dive into the instagrammable features of National Garden Of Athens, a must-visit botanical garden in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Technopolis City Of Athens, a notable cultural center.

At the end of the day, you will drive to Chalkida, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Chalkida's most popular restaurants, and connect with friendly locals for a true cultural experience.

Make sure to reserve a table at Stavento, an iconic dining spot in Chalkida. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of 25 DRAMIA, a popular restaurant in Chalkida. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Psistaria Apostoloy, a hidden gem nestled in Chalkida. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Boheme Cafe Bar, a well-loved spot among locals and tourists. Or, head to Galatiko Chorio. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Euan, another top-rated place in the area.

Savor another day of unforgettable experiences in Greece!

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Day 8

Day 8

  • Chalkida
  • Larissa
  • More

Drive 301 km, 3 hours 34 min

  • Waterfront of Chalkida
  • Karababa Castle
  • Memorial of Leonidas and 300 Spartans
  • More

On day 8 of your road trip in Greece, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Chalkida and Thermopyles are on today's agenda. In the evening, you’ll end up in Larissa, where you will stay for 1 night.

Enjoy all that Chalkida's Seaside has to offer. This is an increasingly popular boardwalk you should not miss. Another must-see is Karababa Castle, an up-and-coming castle in Chalkida.

When you’re ready for the next sight, head to Memorial To Leonidas And 300 Spartans.

When you’re done exploring for the day, you’ll drive to your hotel in Larissa. Check in and relax before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Larissa, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at Nonna Rossa, a popular restaurant in Larissa. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Larissa at Vosporos | Restaurant • Bar, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated THE ALLEY. It’s yet another ideal choice to enhance your time in Larissa tonight.

Keep the evening going at Sherlock Easy Bar, a great choice for enjoying the after-dinner hours with a drink. You could also go to Kiou, which offers a similarly pleasant setting and great drinks. Another option is Wisedog, which provides an inviting environment for unwinding after a busy day out.

Relax and look forward to more memorable moments to come!

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Day 9

Day 9

  • Larissa
  • Ioannina
  • More

Drive 199 km, 4 hours 20 min

  • Trikala City Center Square
  • Matsopoulos Park
  • Meteora
  • Monastery of Varlaam
  • More

Dive into day 9 of your remarkable road trip in Greece. Today you'll explore 2 destinations, including Trikala and Kastraki. At the end of the day, you’ll unwind at one of the finest accommodations in Ioannina, where you'll spend 1 night.

Trikala City Center Square leaves a lasting impression. This public square is one of the most frequently visited places to visit in Larissa. Next, head to Matsopoulos Park, a curiosity-inducing park, known for its visually striking features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Meteora. This visually striking monastery is a highly recommended experience. Nearby, you'll also find Monastery Of Varlaam. Visit these for an interesting touch to your journey.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Ioannina. Ioannina offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Ioannina. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delicious dinner at Spitaki me thea, an excellent option for tonight's dining. Looking for something different? Frontzoy Politeia - Frontzu Politia Restaurant offers a tantalizing alternative with its diverse menu. And don’t miss Papi Cafe Bistro. Known for great service, it’s a fantastic choice for tonight in Ioannina.

Following your dinner, dive into the local bar culture at Scala. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Route 66 Bar, the perfect place for those looking to experience the best of the nightlife. Similarly, Palia Agora provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Get a good night's sleep and look forward to another great day on the road in Greece!

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Day 10

Day 10

  • Ioannina - Departure day
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  • Kaloutsiani Mosque
  • More

Day 10 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Ioannina before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Kaloutsiani Mosque. This curiosity-inducing mosque is a hotspot among locals.

Take some time to indulge in shopping at Ioannina’s popular marketplace, Epirus Street. Look for keepsakes or souvenirs to remind you of your trip. Browse boutiques to find unique and stylish fashion pieces. Wrap up your shopping with a drink and some pastries at a cozy cafe.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Ioannina.

Dine in style at PRESVEIA Restaurant Meze, a top recommendation for dinner tonight. Or, for a change of pace, Frontzu Politia - Hotel boasts a menu that's sure to impress.

You’ll then say farewell to Ioannina. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
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Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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