10-Day Greece Self-Drive Road Trip With Itinerary from Kavala Prefecture to Thessaloniki and Afytos

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Photo of aerial view the city of Kavala in northern Greek, ancient aqueduct Kamares, homes and beaches.
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Description

Escape the ordinary with this exciting 10-day road trip through Greece. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Greece. You will spend 3 nights in Kavala Prefecture, 2 nights in Thessaloniki, and 4 nights in Afytos. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Kavala Prefecture, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Kavala Prefecture, Krinides, Lydia, Thessaloniki, Pella, Vergina, Kassandreia, Afytos, Nea Fokaia, Nea Kallikrateia, Sarti, Siviri, Petralona, Arnaia, Stagira, Rentina, Nea Kerdylia, and Amfipoli, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
Drop-off: 10:00

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Day 1

Day 1

  • Kavala - Arrival day
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  • Lighthouse of Kavala
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Welcome to Kavala Prefecture, the perfect starting point for your road trip in Greece! Pick up your rental car and let the adventure begin. You will spend 2 nights discovering what to see in Kavala Prefecture before embarking on the next leg of your journey.

Kavala Prefecture is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Kavala Prefecture. Check-in typically starts around 2 to 4 PM at hotels in Greece. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Kavala Prefecture, it's often a good idea to reserve a table in advance.

Raise a toast to the start of your 10-day road trip in Greece!

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Day 2

Day 2

  • Kavala
  • More

Drive 37 km, 1 hour 43 min

  • Kavala Fort
  • Kamares
  • Tobacco Museum of Municipality of Kavala
  • Ancient theatre of Philippi
  • Archaeological Museum of Philippi
  • Holy Baptistery of Saint Lydia of Philippi
  • More

Greet day 2 of your road trip in Greece with a smile and start your day with a hearty breakfast. You have 1 night to stay in Kavala Prefecture, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Kavala Prefecture, Krinides, and Lydia.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Kavala Prefecture.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Kavala Prefecture, it's often a good idea to reserve a table in advance.

Take some time to reflect on your day and savor another beautiful night in Greece.

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Day 3

Day 3

  • Kavala
  • Thessaloniki
  • More

Drive 163 km, 2 hours 35 min

  • Museum of Byzantine Civilization
  • The Umbrellas by Zongolopoulos
  • White Tower of Thessaloniki
  • Aristotelous Square
  • More

On day 3 of your road trip in Greece, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Thessaloniki are on today's agenda. In the evening, you’ll end up in Thessaloniki, where you will stay for 2 nights.

At the end of the day, you will drive to Thessaloniki, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Thessaloniki. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Relax and recharge in preparation for another adventurous day in Greece!

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Day 4

Day 4

  • Thessaloniki
  • More

Drive 167 km, 2 hours 53 min

  • Kapani
  • Agias Sofias Square
  • Cathedral of Agia Sophia Thessaloniki
  • Arch of Galerius
  • Archaeological Museum of Pella
  • Museum of the Royal Tombs at Aigai (Aegae)
  • More

On day 4 of your road trip, you'll get the chance to experience Thessaloniki, Pella, and Vergina. At the end of the day, you'll drive back to Thessaloniki, where you still have 1 night left to stay.

When you’re done exploring for the day, you’ll return to Thessaloniki and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Thessaloniki's best restaurants.

Say good night to Thessaloniki and look forward to another great day of your road trip in Greece!

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Day 5

Day 5

  • Thessaloniki
  • Afytos
  • More

Drive 190 km, 2 hours 42 min

  • Tzikas' Family Winery
  • Folklore Museum of Athitos
  • Σπήλαιο Αγιάσματος Αποστόλου Παύλου
  • Nea Kalikratia Central Square
  • More

Experience an unparalleled adventure on day 5 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 4 places, which are Kassandreia, Afytos, Nea Fokaia, and Nea Kallikrateia. At the end of the day, you will retreat to the hotel of your choice in Afytos, where will spend 4 nights.

When you’re done exploring for the day, you’ll drive to your hotel in Afytos. Check in and relax before you head out to tour the village.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Afytos. Enjoy a relaxing evening as you savor delicious local cuisine.

Head back to your accommodation in Afytos and get some rest to prepare for another magical day of your road trip in Greece.

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Day 6

Day 6

  • Afytos
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Drive 72 km, 1 hour 36 min

  • Possidi Cape
  • Possidi beach
  • Ιερός Ναός Παναγίας Φανερωμένης
  • More

You have 3 nights left in Afytos. Take the opportunity to experience more of the best attractions and activities in the village.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Greece. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Afytos's best restaurants.

Celebrate another amazing day of your road trip adventure in Greece!

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Day 7

Day 7

  • Afytos
  • More

Drive 220 km, 3 hours 46 min

  • Θέση θέασης Παραλίας Συκιάς
  • Heart-Shaped Bay
  • Paradise Kavourotripes Beach
  • More

On day 7 of your road trip, you’ll start and end your day in Afytos, where you have 2 nights left to stay.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Afytos.

Indulge in a memorable dining experience at one of Afytos's most popular restaurants, and connect with friendly locals for a true cultural experience.

As the sun sets, rest up and recharge for the next leg of your road trip in Greece.

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Day 8

Day 8

  • Afytos
  • More

Drive 166 km, 2 hours 53 min

  • Agios Nikolaos Beach
  • Petralona Cave
  • Saint Anastasia Farmakolytria Monastery
  • More

On day 8 of your road trip, you’ll start and end your day in Afytos, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate village, including Siviri and Petralona.

When you’re done exploring for the day, you’ll return to Afytos and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Afytos. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Relax and look forward to more memorable moments to come!

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Day 9

Day 9

  • Afytos
  • Kavala
  • More

Drive 236 km, 3 hours 50 min

  • ΑΛΣΟΣ ΑΓΙΑΣ ΠΑΡΑΣΚΕΥΗΣ
  • Κεντρική Πλατεία Αρναίας
  • Aristotle's Park
  • Byzantine Castle of Rentina
  • Lion of Amphipolis
  • Archaeological Museum of Amphipolis
  • More

Your itinerary for day 9 of your road trip in Greece includes 5 stops and features some of the highlights of Arnaia, Stagira, Rentina, Nea Kerdylia, and Amfipoli. At the end of the day, enjoy the comforts of a top-rated hotel in Kavala Prefecture, where you'll spend 1 night.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Kavala Prefecture. Kavala Prefecture offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Kavala Prefecture's most popular restaurants, and connect with friendly locals for a true cultural experience.

Take some time to reflect on your day and savor another beautiful night in Greece.

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Day 10

Day 10

  • Kavala - Departure day
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  • Cross & fire lookout station
  • More

Day 10 of your road trip in Greece is your departure day. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation.

Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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