10-Day Greece Self-Drive Road Trip With Itinerary from Kavala Prefecture to Thessaloniki and Afytos

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Explore the best of Greece on a 10-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Kavala Prefecture, Krinides, Lydia, Thessaloniki, Pella, Vergina, Kassandreia, Afytos, Nea Fokaia, Nea Kallikrateia, Sarti, Siviri, Petralona, Arnaia, Stagira, Rentina, Nea Kerdylia, and Amfipoli. This road trip itinerary in Greece seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 3 nights in Kavala Prefecture, 2 nights in Thessaloniki, and 4 nights in Afytos. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Kavala Prefecture, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable The Umbrellas Sculpture By Zogolopoulos, learn more about the unique Arch Of Galerius And Rotunda, and immerse yourself in the vibrant atmosphere of Kapani.

As you hit the open road and drive through Kavala Prefecture, Krinides, Lydia, Thessaloniki, Pella, Vergina, Kassandreia, Afytos, Nea Fokaia, Nea Kallikrateia, Sarti, Siviri, Petralona, Arnaia, Stagira, Rentina, Nea Kerdylia, and Amfipoli, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Lighthouse of Kavala
Kavala FortKamaresTobacco Museum of Municipality of KavalaAncient theatre of PhilippiArchaeological Museum of PhilippiHoly Baptistery of Saint Lydia of Philippi
Museum of Byzantine CivilizationThe Umbrellas by ZongolopoulosWhite Tower of ThessalonikiAristotelous Square
KapaniAgias Sofias SquareCathedral of Agia Sophia ThessalonikiArch of GaleriusArchaeological Museum of PellaMuseum of the Royal Tombs at Aigai (Aegae)
Tzikas' Family WineryFolklore Museum of AthitosΣπήλαιο Αγιάσματος Αποστόλου ΠαύλουNea Kalikratia Central Square
Possidi CapePossidi beachΙερός Ναός Παναγίας Φανερωμένης

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Day 1

Day 1

  • Kavala - Arrival day
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  • Lighthouse of Kavala
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Your road trip adventure in Greece begins as soon as you reach Kavala Prefecture and pick up your car. You’ll stay in Kavala Prefecture for 2 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Kavala Prefecture is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Lighthouse Of Kavala, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Kavala Prefecture. Check-in typically starts around 2 to 4 PM at hotels in Greece. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Kavala Prefecture, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at Meltemi, a popular restaurant in Kavala Prefecture. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Kavala Prefecture at Tsalapeteinos (Tsalapeteinos Urban Farm), another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Marine Cafe Bar Restaurant. It’s yet another ideal choice to enhance your time in Kavala Prefecture tonight.

Round off your dining experience by visiting Sofita, a prime location for a drink. Alternatively, explore the distinctive characteristics of Beyond Cafe-bar, a bar catering to every mood and preference. Brickwall Pub likewise offers a unique atmosphere, perfect for a memorable night out.

Raise a toast to the start of your 10-day road trip in Greece!

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Day 2

Day 2

  • Kavala
  • More

Drive 37 km, 1 hour 43 min

  • Kavala Fort
  • Kamares
  • Tobacco Museum of Municipality of Kavala
  • Ancient theatre of Philippi
  • Archaeological Museum of Philippi
  • Holy Baptistery of Saint Lydia of Philippi
  • More

On day 2 of your road trip, you’ll start and end your day in Kavala Prefecture, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Kavala Prefecture, Krinides, and Lydia. You still have 1 night left in Kavala Prefecture.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Kavala Prefecture allows for both. Start by heading to Kavala Fortress. This worthwhile castle provides an insightful glimpse into the city's identity. Next, discover Kamares, an instagrammable monument, promising a delightful encounter.

Continue your sightseeing with a visit to Kavala Municipality Tobacco Museum, an intriguing museum. When you’re done, don’t forget to make a stop at the increasingly popular Ancient Theatre Of Philippi. Not far away from the archeological site, you will find the majestic Holy Baptistery Of Saint Lydia Of Philippi, perfect for a quick visit. Round off your day at Archaeological Museum Of Philippi, another gem in Kavala Prefecture with UNESCO world heritage-listed features to discover.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Kavala Prefecture.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Kavala Prefecture. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Have a fantastic dining experience at FRANCO'S, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Psaraki offers an enticing alternative with its varied menu. Additionally, Proto Katsiki is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Kavala Prefecture.

Cap off your dinner by heading to Blue, ideal for a leisurely evening with a drink in hand. Meta Tis Deka is another bar that offers an enjoyable setting. Similarly, Ypobrýchio is also a popular place to go on a night out, perfect for relaxing and socializing.

Raise your glass to another unforgettable day in Greece!

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Day 3

Day 3

  • Kavala
  • Thessaloniki
  • More

Drive 163 km, 2 hours 35 min

  • Museum of Byzantine Civilization
  • The Umbrellas by Zongolopoulos
  • White Tower of Thessaloniki
  • Aristotelous Square
  • More

Dive into day 3 of your remarkable road trip in Greece. Today you will explore Thessaloniki, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Thessaloniki. You’ll stay here for 2 nights.

Today’s route brings family-friendly attractions, picturesque spots, and historic treasures. The first attraction of today is Museum Of Byzantine Culture. This increasingly popular museum is a history-steeped place to see in Kavala Prefecture. Continue your discovery at The Umbrellas Sculpture By Zogolopoulos, a stunning art installation with stories to tell.

As you stroll around Kavala Prefecture, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to White Tower Of Thessaloniki. This spectacular monument offers a culturally significant encounter with Kavala Prefecture. Next, make your way to Aristotelous Square to add another highlight to your day. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Kavala Prefecture.

When you’re done exploring for the day, you’ll drive to your hotel in Thessaloniki. Check in and spend some time relaxing before you head out to tour the city.

As you explore more of Thessaloniki, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a delightful dinner at Kitchen Bar, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try The Greek? It's another excellent option with a diverse menu. Consider reserving a table at Phanós as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Thessaloniki.

Cap off your dinner by heading to Beetle Bar, ideal for a leisurely evening with a drink in hand. Vogatsikou 3 is another bar that offers an enjoyable setting. Similarly, Souel is also a popular place to go on a night out, perfect for relaxing and socializing.

Get a good night's sleep and look forward to another great day on the road in Greece!

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Day 4

Day 4

  • Thessaloniki
  • More

Drive 167 km, 2 hours 53 min

  • Kapani
  • Agias Sofias Square
  • Cathedral of Agia Sophia Thessaloniki
  • Arch of Galerius
  • Archaeological Museum of Pella
  • Museum of the Royal Tombs at Aigai (Aegae)
  • More

Wake up to day 4 of your extraordinary road trip in Greece. With 1 night left in Thessaloniki, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Get ready for a day filled with fun adventures, photo-friendly spots, and historic treasures in the charming city of Thessaloniki. Your adventure starts at Kapani, a locally renowned local hot spot. Another notable attraction to explore is Agias Sofias Square. This interesting public square is known for its historic appeal.

After soaking in the highlights of these sights, take some time to wander Thessaloniki's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Holy Church Of Hagia Sophia. This stunning church offers a fascinating experience that many visitors find memorable. Arch Of Galerius And Rotunda is also worth visiting, along with Archaeological Museum Of Pella. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at Museum Of The Royal Tombs At Aigai (aegae). This worthwhile museum provides a fitting finale to your sightseeing.

When you’re done exploring for the day, you’ll return to Thessaloniki and your accommodation.

Indulge in a memorable dining experience at one of Thessaloniki's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a delicious meal at Mamalouka, a highly-rated dining destination in Thessaloniki. If you're eager to try something different, consider Clochard, another top spot with a tantalizing menu. You might also want to secure a reservation at Sofi's House Restaurant. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Thessaloniki this evening.

Continue your evening by exploring the vibrant nightlife scene at Castra- All Day Terrace Bar, a prime destination for a thrilling night out. Also, don’t forget to check out Barbaben - Bar/ba/ben, a bar that offers unique local touches. Likewise, Apallou provides an excellent alternative for a fun evening.

Say good night to Thessaloniki and look forward to another great day of your road trip in Greece!

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Day 5

Day 5

  • Thessaloniki
  • Afytos
  • More

Drive 190 km, 2 hours 42 min

  • Tzikas' Family Winery
  • Folklore Museum of Athitos
  • Σπήλαιο Αγιάσματος Αποστόλου Παύλου
  • Nea Kalikratia Central Square
  • More

Embark on another extraordinary experience on day 5 of your road trip in Greece. Today, you will make 4 stops and experience some of the highlights of Kassandreia, Afytos, Nea Fokaia, and Nea Kallikrateia. At the end of the day, you will enjoy the comforts of a top-rated hotel in Afytos, which will be your home away from home for 4 nights.

Get ready for a day filled with family-friendly attractions, romantic experiences, and scenic views in the charming town of Thessaloniki. Your adventure starts at Tzikas' Family Winery, a frequently visited local hot spot. Another notable attraction to explore is Folklore Museum Of Athitos. This up-and-coming museum is known for its enchanting appeal.

After soaking in the highlights of these sights, take some time to wander Thessaloniki's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Cave Of Saint Paul The Apostle. This stunning cave offers a fascinating experience that many visitors find memorable. Nea Kalikratia Central Square is also worth visiting.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Afytos. Afytos offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Afytos's best restaurants.

Don’t miss out on dining at TAVERNA to STEKI, a top-rated dining destination in Afytos. If you're in the mood to try something new, consider vouka, another top spot with a mouthwatering menu. You might also want to secure a reservation at To Kyma. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Afytos this evening.

Continue the enjoyment post-dinner at Afutaion Agora Koozina Bar, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Fortuna offers a vibrant space for indulging in well-crafted drinks and engaging conversation.

Head back to your accommodation in Afytos and get some rest in preparation for another magical day of your road trip in Greece!

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Day 6

Day 6

  • Afytos
  • More

Drive 72 km, 1 hour 36 min

  • Possidi Cape
  • Possidi beach
  • Ιερός Ναός Παναγίας Φανερωμένης
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Day 6 of your road trip will take you to the best attractions Afytos has to offer. Cherish the 3 nights you have left in Afytos by discovering the best things there are to see and do in the village.

Today's adventure in Afytos promises more breathtaking discoveries and enriching experiences! Begin at Possidi Cape. This serene beach is a highlight of any visit in the village. Then, enjoy Possidi Beach, another romantic attraction that never fails to captivate visitors. Next, head over to Ieros Naos Panagias Faneromenis, one of the village’s most increasingly popular attractions, known for its stunning features.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Greece is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Afytos, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Have a fantastic dining experience at Ta Mpakaliarakia Tou Peirati, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Oceanides Seafood Restaurant offers an enticing alternative with its varied menu. Additionally, Notos All Day Bar is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Afytos.

Get a good night's sleep and look forward to another great day on the road in Greece!

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Day 7

Day 7

  • Afytos
  • More

Drive 220 km, 3 hours 46 min

  • Θέση θέασης Παραλίας Συκιάς
  • Heart-Shaped Bay
  • Paradise Kavourotripes Beach
  • More

Greet day 7 of your road trip in Greece with a smile and start your day with a hearty breakfast. You will return to Afytos for your remaining 2 nights in the village later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Paralia Sykias and Sarti.

Get ready to discover some of the most iconic wonders in Afytos, including an observation deck and a beach. Start your day at Thesi Theasis Paralias Sukias. This mesmerizing observation deck is a beloved place to see in Afytos. Then, wander over to Heart-shaped Bay. If romantic sites excite you, this beach will be right up your alley. Nearby, you’ll also find Paradise Kavourotripes Beach. This romantic beach is a favorite among visitors.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Afytos.

After a day of adventure, treat yourself to an exquisite dinner at one of Afytos's best restaurants.

Dine in style at To Palio Rementzo, a top recommendation for dinner tonight. Or, for a change of pace, Zoyias Sweets & Drinks (📍Afitos) boasts a menu that's sure to impress. Also, be sure to check out Mpogiata. Known as a local hotspot, it’s a great choice for tonight in Afytos.

Take some time to reflect on your day and savor another beautiful night in Greece.

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Day 8

Day 8

  • Afytos
  • More

Drive 166 km, 2 hours 53 min

  • Agios Nikolaos Beach
  • Petralona Cave
  • Saint Anastasia Farmakolytria Monastery
  • More

On day 8 of your road trip, you’ll start and end your day in Afytos, where you'll stay for 1 night more.

Discover a day packed with fun adventures, romantic experiences, and natural wonders in Afytos. Begin your sightseeing with Agios Nikolaos Beach. This underrated beach is one of the top attractions in the village. Proceed to Petralona Cave, another must-visit attraction.

As you wander through the inviting streets of Afytos, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Saint Anastasia Farmakolytria Monastery. This underrated monastery is a traveler-favorite.

When you’re done exploring for the day, you’ll return to Afytos and your accommodation.

As you explore more of Afytos, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a lovely dining experience at To Steki fast food, a popular restaurant in Afytos. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Afytos at Sto. Psito, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated.

Celebrate another amazing day of your road trip adventure in Greece!

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Day 9

Day 9

  • Afytos
  • Kavala
  • More

Drive 236 km, 3 hours 50 min

  • ΑΛΣΟΣ ΑΓΙΑΣ ΠΑΡΑΣΚΕΥΗΣ
  • Κεντρική Πλατεία Αρναίας
  • Aristotle's Park
  • Byzantine Castle of Rentina
  • Lion of Amphipolis
  • Archaeological Museum of Amphipolis
  • More

On day 9 of your road trip in Greece, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Arnaia, Stagira, Rentina, Nea Kerdylia, and Amfipoli. In the evening, you’ll end up in Kavala Prefecture, where you will stay for 1 night.

Today’s well-planned self-sightseeing route offers several fun adventures, natural wonders, and breathtaking views. Whether you decide to explore Afytos on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Άlsos Agias Paraskeuis is the first of them. Spend some time admiring this picturesque park before continuing your journey. Kentriki Plateia Arnaias is your next stop. This often recommended public square is one of the best-rated sights in Afytos.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Aristotle's Park. This noteworthy park is a sight to behold. To round off your sightseeing experience, visit Byzantine Settlement - Castle Of Rentina and Lion Of Amphipolis. If time allows, end your day with Archaeological Museum Of Amphipolis, a heritage-rich museum that offers a memorable conclusion to your exploration.

At the end of the day, you will drive to Kavala Prefecture, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Kavala Prefecture. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a lovely meal at “Paraliakon” Estiatorio, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, 180° sun & lounge is another top choice with a popular menu. You could also check for a table at Krokodeilos. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Kavala Prefecture tonight.

Following your dinner, dive into the local bar culture at 1901 Old Town Cafe Wine Bar. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Lychnari Cafe, the perfect place for those looking to experience the best of the nightlife. Similarly, La Place provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Savor another day of unforgettable experiences in Greece!

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Day 10

Day 10

  • Kavala - Departure day
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  • Cross & fire lookout station
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Day 10 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Kavala Prefecture before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Cross & Fire Lookout Station, a romantic observation deck before you head out.

As your final day in Greece unfolds, enjoy a last-minute shopping spree in Kavala Prefecture's best shopping area. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Greece.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Kavala Prefecture.

Savor the flavors at Tsipouradiko Nemesis, a top pick for dinner tonight. Alternatively, tavern Koutoukaki beckons with its unique menu offerings.

You’ll then say farewell to Kavala Prefecture. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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