10-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki to Kalambaka, Athens, Nafplio, and Patras

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Photo of Saint Paul cathedral in Thessaloniki, Greece.
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Escape the ordinary with this exciting 10-day road trip through Greece. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Greece. You will spend 3 nights in Thessaloniki, 1 night in Kalambaka, 3 nights in Athens, 1 night in Nafplio, and 1 night in Patras. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. Acropolis Of Athens and Parthenon are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Acropolis Museum, learn more about the unique White Tower Of Thessaloniki, and immerse yourself in the vibrant atmosphere of Aristotelous Square.

As you hit the open road and drive through Thessaloniki, Kastraki, Kalambaka, Athens, Delphi, Nafplio, Lighourio, Patras, Ioannina, and Perama, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Day 1

Day 1

  • Thessaloniki - Arrival day
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  • Ladadika
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Welcome to Thessaloniki, the perfect starting point for your road trip in Greece! Pick up your rental car and let the adventure begin. You will spend 2 nights discovering what to see in Thessaloniki before embarking on the next leg of your journey.

Thessaloniki is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Thessaloniki. Check-in typically starts around 2 to 4 PM at hotels in Greece. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Kitchen Bar, a top-rated dining destination in Thessaloniki. If you're in the mood to try something new, consider The Greek, another top spot with a mouthwatering menu. You might also want to secure a reservation at Phanós. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Thessaloniki this evening.

Continue the enjoyment post-dinner at Beetle Bar, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Vogatsikou 3 offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Souel. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Raise a toast to the start of your 10-day road trip in Greece!

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Day 2

Day 2

  • Thessaloniki
  • More

Drive 6 km, 56 min

  • Archaeological Museum of Thessaloniki
  • White Tower of Thessaloniki
  • Arch of Galerius
  • Agias Sofias Square
  • Aristotelous Square
  • Tsimiski Street
  • More

On day 2 of your road trip, you will have an entire day to discover what to see in Thessaloniki. You’ll stay in Thessaloniki for 1 night.

Tsimiski Street is a fantastic place you can explore today in Thessaloniki. This street is a testament to the city’s character, and it's easy to spend hours just walking around and admiring the surroundings. Soak in the Thessaloniki-way-of-life and visit all the nearby sights.

Archaeological Museum Of Thessaloniki makes a great addition to your morning plans. This often recommended museum is a visually striking place to see in Thessaloniki. Continue your discovery at White Tower Of Thessaloniki, a culturally significant monument with stories to tell.

As you stroll around Thessaloniki, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Arch Of Galerius And Rotunda. This interesting monument offers an eye-catching encounter with Thessaloniki. Next, make your way to Agias Sofias Square to add another highlight to your day. After that, visit Aristotelous Square, a popular public square that’s sure to impress. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Thessaloniki.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Greece. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at Mamalouka, an excellent option for tonight's dining. Looking for something different? Clochard offers a tantalizing alternative with its diverse menu. And don’t miss Sofi's House Restaurant. Known for great service, it’s a fantastic choice for tonight in Thessaloniki.

After enjoying a fulfilling meal, continue your evening at Castra- All Day Terrace Bar, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Barbaben - Bar/ba/ben offers a welcoming atmosphere for easing into the nightlife. Similarly, Apallou provides an excellent environment for a relaxed and enjoyable evening.

Relax and recharge in preparation for another adventurous day in Greece!

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Day 3

Day 3

  • Thessaloniki
  • Meteora
  • More

Drive 240 km, 3 hours 33 min

  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Monastery of Varlaam
  • Main Observation Deck of Meteora
  • Natural History Museum of Meteora and Mushroom Museum
  • More

Dive into day 3 of your remarkable road trip in Greece. Today you'll explore 2 destinations, including Kastraki and Kalambaka. At the end of the day, you’ll unwind at one of the finest accommodations in Kalambaka, where you'll spend 1 night.

Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour is an ideal stop early in the day. This worthwhile monastery is a must-visit in the village. When you’re ready for your next discovery, continue to Monastery Of Varlaam, which may be one of the most stunning places you will experience today.

One of the best things about exploring Thessaloniki on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Main Observation Deck Of Meteora, a locally appreciated observation deck in the village. If you’re up for more discoveries, don’t forget to reserve some time for Natural History Museum Of Meteora And Mushroom Museum.

When you’re done exploring for the day, you’ll drive to your hotel in Kalambaka. Check in and relax before you head out to tour the town.

Indulge in a memorable dining experience at one of Kalambaka's most popular restaurants, and connect with friendly locals for a true cultural experience.

Get a good night's sleep and look forward to another great day on the road in Greece!

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Day 4

Day 4

  • Meteora
  • Athens
  • More

Drive 352 km, 4 hours 27 min

  • Greek Education Museum
  • Meteora Digital Projection Center
  • Monastery of the Holy Trinity at Meteora
  • Monastery of St Stephan
  • More

Your itinerary for day 4 of your road trip in Greece includes 1 stop and features some of the highlights of Kalambaka. At the end of the day, enjoy the comforts of a top-rated hotel in Athens, where you'll spend 3 nights.

No visit to Kalambaka is complete without Greek Education Museum. This increasingly popular museum is one of the top attractions in the town. Proceed to Meteora Digital Projection Center, another must-visit attraction.

As you wander through the inviting streets of Kalambaka, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Monastery Of The Holy Trinity At Meteora. This intriguing monastery is a traveler-favorite. Not far away, you’ll find Holy Monastery Of Saint Stephan, another key site on your sightseeing itinerary.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Athens. Athens offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Athens's best restaurants.

Dine in style at Zampano, a top recommendation for dinner tonight. Or, for a change of pace, Rosalia boasts a menu that's sure to impress. Also, be sure to check out NJV Athens Plaza. Known as a local hotspot, it’s a great choice for tonight in Athens.

Continue the enjoyment post-dinner at Mayros Gatos, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Kuko's The Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Revolt Street Bar. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Say good night to Athens and look forward to another great day of your road trip in Greece!

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Day 5

Day 5

  • Athens
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Drive 365 km, 4 hours 46 min

  • Delphi Archaeological Museum
  • Castalian Spring
  • Temple of Apollo
  • More

On day 5 of your road trip, you’ll start and end your day in Athens, where you have 2 nights left to stay.

Delphi Archaeological Museum is must-visit museum and a great option for a daytime tour of the area. Continue your journey to Castalian Spring, a worthwhile archeological site, located just a leisurely stroll away. Next, head to Temple Of Apollo In Delphi, a historic archeological site, also available for your discovery today.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Athens.

Indulge in a memorable dining experience at one of Athens's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy a lovely meal at Harvest Coffee & Wine, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, 42 Barstronomy Athens is another top choice with a popular menu. You could also check for a table at O Babas. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Athens tonight.

Round off your dining experience by visiting Tiki Bar Athens, a prime location for a drink. Alternatively, explore the distinctive characteristics of Brettos, a bar catering to every mood and preference. Luxus Bar Bistro likewise offers a unique atmosphere, perfect for a memorable night out.

Relax and look forward to more memorable moments to come!

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Day 6

Day 6

  • Athens
  • More

Drive 4 km, 1 hour 2 min

  • Parthenon
  • Acropolis of Athens
  • Acropolis Museum
  • Ermou Street
  • Plaka
  • Monastiraki
  • More

Day 6 of your road trip across Greece promises a magnificent time exploring what to see in Athens. You have 1 night left in Athens. Take the opportunity to experience more of the best attractions and activities in the city.

One of the most iconic spots you can visit today is Ermou Street. Allow yourself some time to explore this street and discover its unique quirks. You'll also find many of the best sightseeing spots nearby. You can also explore Plaka, a neighborhood that offers a glimpse into local life and culture.

To truly experience Athens, make sure to drop by Parthenon. This top-rated archeological site is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Acropolis Of Athens, one of the city’s best highlights.

Next, check out Acropolis Museum, one of the most extraordinary places to see in Athens. This museum is a favorite among locals and travelers alike.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Greece. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Athens's best restaurants.

Enjoy a delicious meal at Cookoovaya, a highly-rated dining destination in Athens. If you're eager to try something different, consider Karamanlidika, another top spot with a tantalizing menu. You might also want to secure a reservation at Estiatorio Auli. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Athens this evening.

Continue the enjoyment post-dinner at Kazu Cafe-bar, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Upupa Epops - The Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Gazarte. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

As the sun sets, rest up and recharge for the next leg of your road trip in Greece.

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Day 7

Day 7

  • Athens
  • Nafplio
  • More

Drive 193 km, 3 hours 3 min

  • Nafplio Lighthouse
  • Nafplio Port
  • Archaeological Site of the Sanctuary of Asclepius at Epidaurus
  • Archaeological Museum of the Asklepeion at Epidaurus
  • Ancient Theatre at the Asclepieion of Epidaurus
  • More

On day 7 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 2 destinations, including Nafplio and Lighourio. When you’re not sightseeing, take time to relax at your chosen hotel in Nafplio, where you’ll be staying for 1 night.

One of the most frequently visited attractions included on the itinerary is Nafplio Lighthouse. This enchanting lighthouse will help you start your sightseeing on top. Then, take a leisurely stroll to Nafplio Port and learn what makes this history-steeped marina unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the beloved Archaeological Site Of The Sanctuary Of Asclepius At Epidaurus. After exploring the archeological site, head to Archaeological Museum Of The Asclepieion Of Epidaurus. This intriguing museum is a highlight in Athens. As your day continues, stop by Ancient Theatre At The Asclepieion Of Epidaurus, known for its picture-perfect features.

At the end of the day, you will drive to Nafplio, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Nafplio is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Nafplio.

Savor the flavors at Arapakos, a top pick for dinner tonight. Alternatively, The Corner of Kavalaris beckons with its unique menu offerings. Also, consider To Omorfo Tavernaki. With its consistent customer satisfaction, it’s an excellent option for dining in Nafplio tonight.

Explore the vibrant nightlife at Jukebox Espresso Bar after your meal, a hub for lively evenings and memorable moments. Or, head to Allotino Coffee & Bar for a great selection of flavorful drinks and a charming setting.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Greece.

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Day 8

Day 8

  • Nafplio
  • Patras
  • More

Drive 192 km, 4 hours 1 min

  • Lion of the Bavarians
  • Nafplio national gallery
  • War Museum Nafplio
  • Church of Saint Spyridon
  • Akronauplía
  • Palamidi
  • More

Experience an unparalleled adventure on day 8 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Nafplio. At the end of the day, you will retreat to the hotel of your choice in Patras, where will spend 1 night.

Lion Of The Bavarians, Nafplion is perfect for a self-paced visit during the day. This historic monument is sure to impress. Next on your list is Nafplio National Gallery, another must-visit landmark and worthwhile art gallery renowned for its standout features.

While exploring and sightseeing, take time to savor the culture of Nafplio by sampling some local delicacies. When you’re ready for more sightseeing, head to War Museum Nafplio. This heritage-rich military museum is an essential place to visit for anyone looking for the full Nafplio experience. We also recommend visiting Church Of Saint Spyridon, a locally appreciated church. Nearby, you'll also find Fortress Of Akronauplía, ready to add charm to your journey. End your self-guided sightseeing tour with a stop at Palamidi and wrap up your day with its visually striking appeal.

When you’re done exploring for the day, you’ll drive to your hotel in Patras. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Patras. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely meal at Tag, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Bianco is another top choice with a popular menu. You could also check for a table at Carousello. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Patras tonight.

Continue your lively evening at Sofita, a perfect place for winding down or revving up the night, depending on which mood you’re in. Charama Therino is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Notos ensures a night out tailored to your taste.

Relax and look forward to more memorable moments to come!

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Day 9

Day 9

  • Patras
  • Thessaloniki
  • More

Drive 476 km, 5 hours 33 min

  • Ioannina Castle
  • Ich Kale Acropolis of Ioannina
  • Cave of Perama
  • More

On day 9 of your road trip in Greece, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Ioannina and Perama are on today's agenda. In the evening, you’ll end up in Thessaloniki, where you will stay for 1 night.

Make time for Ioannina Castle, a popular castle that is worthwhile a visit in the city. Nearby, you’ll find Ic Kale Acropolis Of Ioannina, enchanting visitors with its picture-perfect appeal. Continue your exploration at Cave Of Perama. This cave is one of the city’s most worthwhile spots.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Thessaloniki. Thessaloniki offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Enoches Bar, a top-rated dining destination in Thessaloniki. If you're in the mood to try something new, consider O Loytros, another top spot with a mouthwatering menu. You might also want to secure a reservation at rOOTS. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Thessaloniki this evening.

After enjoying a fulfilling meal, continue your evening at Peiratis Cafe-bar, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, In Rock Cafe Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Tribeca provides an excellent environment for a relaxed and enjoyable evening.

Raise your glass to another unforgettable day in Greece!

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Day 10

Day 10

  • Thessaloniki - Departure day
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  • The Umbrellas by Zongolopoulos
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Day 10 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting The Umbrellas Sculpture By Zogolopoulos, a romantic art installation before you head out.

Take advantage of your accommodation's proximity to Thessaloniki’s shopping district for some last-minute bargain hunting. Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones. Discover boutiques offering an array of stylish fashion choices.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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