10-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki to Kalambaka, Athens, Nafplio, and Patras

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Photo of Saint Paul cathedral in Thessaloniki, Greece.
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Experience the freedom of the open road in Greece as you embark on an unforgettable 10-day road trip! This experience caters to every traveler, featuring destinations like Thessaloniki, Kastraki, Kalambaka, Athens, Delphi, Nafplio, Lighourio, Patras, Ioannina, and Perama.

This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 3 nights in Thessaloniki, 1 night in Kalambaka, 3 nights in Athens, 1 night in Nafplio, and 1 night in Patras. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. Acropolis Of Athens and Parthenon are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Acropolis Museum, learn more about the unique White Tower Of Thessaloniki, and immerse yourself in the vibrant atmosphere of Aristotelous Square.

As you hit the open road and drive through Thessaloniki, Kastraki, Kalambaka, Athens, Delphi, Nafplio, Lighourio, Patras, Ioannina, and Perama, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Ladadika
Archaeological Museum of ThessalonikiWhite Tower of ThessalonikiArch of GaleriusAgias Sofias SquareAristotelous SquareTsimiski Street
The Great Meteoron Holy Monastery of the Transfiguration of the SaviourMonastery of VarlaamMain Observation Deck of MeteoraNatural History Museum of Meteora and Mushroom Museum
Greek Education MuseumMeteora Digital Projection CenterMonastery of the Holy Trinity at MeteoraMonastery of St Stephan
Delphi Archaeological MuseumCastalian SpringTemple of Apollo
ParthenonAcropolis of AthensAcropolis MuseumErmou StreetPlakaMonastiraki

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Day 1

Day 1

  • Thessaloniki - Arrival day
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  • Ladadika
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Your road trip adventure in Greece begins as soon as you reach Thessaloniki and pick up your car. You’ll stay in Thessaloniki for 2 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Thessaloniki is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ladadika, a must-see neighborhood, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Thessaloniki. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Dine in style at Kitchen Bar, a top recommendation for dinner tonight. Or, for a change of pace, The Greek boasts a menu that's sure to impress. Also, be sure to check out Phanós. Known as a local hotspot, it’s a great choice for tonight in Thessaloniki.

Keep the evening going at Beetle Bar, a great choice for enjoying the after-dinner hours with a drink. You could also go to Vogatsikou 3, which offers a similarly pleasant setting and great drinks. Another option is Souel, which provides an inviting environment for unwinding after a busy day out.

Raise a toast to the start of your 10-day road trip in Greece!

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Day 2

Day 2

  • Thessaloniki
  • More

Drive 6 km, 56 min

  • Archaeological Museum of Thessaloniki
  • White Tower of Thessaloniki
  • Arch of Galerius
  • Agias Sofias Square
  • Aristotelous Square
  • Tsimiski Street
  • More

Day 2 offers a multitude of experiences. You will stay in Thessaloniki for 1 night more, offering you enough time to explore at a relaxed pace.

A top thing to do today is to explore Tsimiski Street, a must-see street in Thessaloniki. It's the perfect starting point for touring the top attractions in the area.

Today, you'll explore some of the most beautiful places in Thessaloniki, including a museum, a monument, and a public square. Start your day with a visit to Archaeological Museum Of Thessaloniki. This intriguing museum is a must-visit in the city. When you’re ready for your next discovery, continue to White Tower Of Thessaloniki, which may be one of the most picture-perfect places you will experience today.

One of the best things about exploring Thessaloniki on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Arch Of Galerius And Rotunda, a captivating monument in the city. If you’re up for more discoveries, don’t forget to reserve some time for Agias Sofias Square and Aristotelous Square.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Greece is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Thessaloniki. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Mamalouka, a top-rated dining destination in Thessaloniki. If you're in the mood to try something new, consider Clochard, another top spot with a mouthwatering menu. You might also want to secure a reservation at Sofi's House Restaurant. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Thessaloniki this evening.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Castra- All Day Terrace Bar, known for its inviting atmosphere. Barbaben - Bar/ba/ben is another great option if you’re looking for a place to get the night started. Similarly, Apallou provides a great setting to enjoy the night away.

Raise your glass to another unforgettable day in Greece!

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Day 3

Day 3

  • Thessaloniki
  • Meteora
  • More

Drive 240 km, 3 hours 33 min

  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Monastery of Varlaam
  • Main Observation Deck of Meteora
  • Natural History Museum of Meteora and Mushroom Museum
  • More

On day 3 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 2 destinations, Kastraki and Kalambaka. When you’re not sightseeing, take time to relax at your selected hotel in Kalambaka, where you’ll be staying for 1 night.

Get ready to discover some of the most iconic wonders in Thessaloniki, including a monastery, an observation deck, and a museum. Start your day at Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour. This historic monastery is an often recommended place to see in Thessaloniki. Then, wander over to Monastery Of Varlaam. If picture-perfect sites excite you, this monastery will be right up your alley. Nearby, you’ll also find Main Observation Deck Of Meteora. This mesmerizing observation deck is a favorite among visitors.

Thessaloniki offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Natural History Museum Of Meteora And Mushroom Museum is an often recommended spot in the village that will captivate you with its unique charm.

At the end of the day, you will drive to Kalambaka, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Kalambaka. If you are looking to dine at a popular restaurant in the town, it's often a good idea to reserve a table in advance.

Take some time to reflect on your day and savor another beautiful night in Greece.

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Day 4

Day 4

  • Meteora
  • Athens
  • More

Drive 352 km, 4 hours 27 min

  • Greek Education Museum
  • Meteora Digital Projection Center
  • Monastery of the Holy Trinity at Meteora
  • Monastery of St Stephan
  • More

On day 4 of your road trip in Greece, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Kalambaka. In the evening, you’ll end up in Athens, where you will stay for 3 nights.

Kalambaka is home to plenty of attractions that offer fun adventures, picturesque spots, and historic treasures! Start at Greek Education Museum, an intriguing museum that is worthwhile a visit in the town. Continue your exploration at Monastery Of The Holy Trinity At Meteora. This monastery is one of the town’s most worthwhile spots.

Enjoy the freedom of exploring Kalambaka at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Holy Monastery Of Saint Stephan.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Athens. Athens offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Athens, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a lovely dining experience at Zampano, a popular restaurant in Athens. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Athens at Rosalia, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated NJV Athens Plaza. It’s yet another ideal choice to enhance your time in Athens tonight.

Continue your evening by exploring the vibrant nightlife scene at Mayros Gatos, a prime destination for a thrilling night out. Also, don’t forget to check out Kuko's The Bar, a bar that offers unique local touches. Likewise, Revolt Street Bar provides an excellent alternative for a fun evening.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Greece.

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Day 5

Day 5

  • Athens
  • More

Drive 365 km, 4 hours 46 min

  • Delphi Archaeological Museum
  • Castalian Spring
  • Temple of Apollo
  • More

Greet day 5 of your road trip in Greece with a smile and start your day with a hearty breakfast. You will return to Athens for your remaining 2 nights in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Delphi.

Today, you'll explore some of the most beautiful places in Athens, including a museum and an archeological site. Start your day with a visit to Delphi Archaeological Museum. This notable museum is a must-visit in the village. When you’re ready for your next discovery, continue to Castalian Spring, which may be one of the most UNESCO world heritage-listed places you will experience today.

One of the best things about exploring Athens on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Temple Of Apollo In Delphi, a worthwhile archeological site in the village.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Athens.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Athens. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Make sure to reserve a table at Harvest Coffee & Wine, an iconic dining spot in Athens. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of 42 Barstronomy Athens, a popular restaurant in Athens. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of O Babas, a hidden gem nestled in Athens. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Keep the evening going at Tiki Bar Athens, a great choice for enjoying the after-dinner hours with a drink. You could also go to Brettos, which offers a similarly pleasant setting and great drinks. Another option is Luxus Bar Bistro, which provides an inviting environment for unwinding after a busy day out.

Take some time to reflect on your day and savor another beautiful night in Greece.

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Day 6

Day 6

  • Athens
  • More

Drive 4 km, 1 hour 2 min

  • Parthenon
  • Acropolis of Athens
  • Acropolis Museum
  • Ermou Street
  • Plaka
  • Monastiraki
  • More

Day 6 of your road trip across Greece promises a magnificent time exploring Athens. You have 1 night left in Athens. Take the opportunity to experience more of the best attractions and activities in the city.

Ermou Street is a street that stands out as one of the must-see places in Athens. Take a moment to explore its distinct atmosphere, and don’t miss the popular sightseeing spots just a short walk away. For another highlight, head to Plaka, a neighborhood offering its own unique experiences.

Today’s well-planned self-sightseeing route offers several fun adventures, breathtaking views, and picturesque spots. Whether you decide to explore Athens on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Parthenon is the first of them. Spend some time admiring this culturally significant archeological site before continuing your journey. Acropolis Of Athens is your next stop. This world-famous archeological site is one of the best-rated sights in Athens.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Acropolis Museum. This historic museum is a sight to behold.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Greece is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Athens's best restaurants.

Make sure to reserve a table at Cookoovaya, an iconic dining spot in Athens. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Karamanlidika, a popular restaurant in Athens. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Estiatorio Auli, a hidden gem nestled in Athens. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Kazu Cafe-bar stands out as an excellent choice for a post-dinner cocktail. Alternatively, Upupa Epops - The Bar offers an ideal atmosphere to enjoy the pleasures of the night. Gazarte is also a great option that provides a perfect setting for a relaxing evening.

Say good night to Athens and look forward to another great day of your road trip in Greece!

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Day 7

Day 7

  • Athens
  • Nafplio
  • More

Drive 193 km, 3 hours 3 min

  • Nafplio Lighthouse
  • Nafplio Port
  • Archaeological Site of the Sanctuary of Asclepius at Epidaurus
  • Archaeological Museum of the Asklepeion at Epidaurus
  • Ancient Theatre at the Asclepieion of Epidaurus
  • More

Dive into day 7 of your remarkable road trip in Greece. Today you will explore Nafplio and Lighourio, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Nafplio. You’ll stay here for 1 night.

Today’s well-planned self-sightseeing route offers several fun adventures, romantic experiences, and scenic views. Whether you decide to explore Athens on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Nafplio Lighthouse is the first of them. Spend some time admiring this enchanting lighthouse before continuing your journey. Nafplio Port is your next stop. This curiosity-inducing marina is one of the best-rated sights in Athens.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Archaeological Site Of The Sanctuary Of Asclepius At Epidaurus. This picture-perfect archeological site is a sight to behold. To round off your sightseeing experience, visit Archaeological Museum Of The Asclepieion Of Epidaurus and Ancient Theatre At The Asclepieion Of Epidaurus.

When you’re done exploring for the day, you’ll drive to your hotel in Nafplio. Check in and spend some time relaxing before you head out to tour the town.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Nafplio. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at Arapakos, a highly-rated dining destination in Nafplio. If you're eager to try something different, consider The Corner of Kavalaris, another top spot with a tantalizing menu. You might also want to secure a reservation at To Omorfo Tavernaki. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Nafplio this evening.

Following your dinner, dive into the local bar culture at Jukebox Espresso Bar. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Allotino Coffee & Bar, the perfect place for those looking to experience the best of the nightlife.

Relax and recharge in preparation for another adventurous day in Greece!

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Day 8

Day 8

  • Nafplio
  • Patras
  • More

Drive 192 km, 4 hours 1 min

  • Lion of the Bavarians
  • Nafplio national gallery
  • War Museum Nafplio
  • Church of Saint Spyridon
  • Akronauplía
  • Palamidi
  • More

Embark on another extraordinary experience on day 8 of your road trip in Greece. Today, you will make 1 stop and experience some of the highlights of Nafplio. At the end of the day, you will enjoy the comforts of a top-rated hotel in Patras, which will be your home away from home for 1 night.

Immerse yourself in Nafplio’s rich culture with today's sightseeing itinerary. Start your journey at Lion Of The Bavarians, Nafplion. This historic monument is sure to ignite your curiosity. Next, dive into the photogenic features of Nafplio National Gallery, a must-visit art gallery in the town.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to War Museum Nafplio, an underrated military museum. For a change of scene, check out Church Of Saint Spyridon, known for its photogenic features. We also recommend visiting Fortress Of Akronauplía. This castle is a must for anyone looking to experience the town to the fullest. Lastly, end your day with a visit to Palamidi, yet another notable attraction in Nafplio.

At the end of the day, you will drive to Patras, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Patras's best restaurants.

Don’t miss out on dining at Tag, a top-rated dining destination in Patras. If you're in the mood to try something new, consider Bianco, another top spot with a mouthwatering menu. You might also want to secure a reservation at Carousello. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Patras this evening.

Keep the evening going at Sofita, a great choice for enjoying the after-dinner hours with a drink. You could also go to Charama Therino, which offers a similarly pleasant setting and great drinks. Another option is Notos, which provides an inviting environment for unwinding after a busy day out.

Relax and reminisce about your day in Greece and look forward to more memorable moments to come!

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Day 9

Day 9

  • Patras
  • Thessaloniki
  • More

Drive 476 km, 5 hours 33 min

  • Ioannina Castle
  • Ich Kale Acropolis of Ioannina
  • Cave of Perama
  • More

Experience an unparalleled adventure on day 9 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Ioannina and Perama. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Thessaloniki. You will spend 1 night here for some well-deserved relaxation.

A blend of family-friendly attractions, romantic experiences, and breathtaking views await you in Patras on today’s itinerary. First up is the locally renowned castle, Ioannina Castle. Afterward, continue to Ic Kale Acropolis Of Ioannina, an archeological site every traveler should visit.

As you explore Patras’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Cave Of Perama. This curiosity-inducing cave is an essential stop.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Thessaloniki. Thessaloniki offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Thessaloniki's most popular restaurants, and connect with friendly locals for an authentic adventure.

Have a fantastic dining experience at Enoches Bar, a highly recommended choice for tonight's dinner. If you're looking to mix things up, O Loytros offers an enticing alternative with its varied menu. Additionally, rOOTS is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Thessaloniki.

Round off your dining experience by visiting Peiratis Cafe-bar, a prime location for a drink. Alternatively, explore the distinctive characteristics of In Rock Cafe Bar, a bar catering to every mood and preference. Tribeca likewise offers a unique atmosphere, perfect for a memorable night out.

Get a good night's sleep and look forward to another great day on the road in Greece!

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Day 10

Day 10

  • Thessaloniki - Departure day
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  • The Umbrellas by Zongolopoulos
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Day 10 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting The Umbrellas Sculpture By Zogolopoulos, a noteworthy art installation before you head out.

Maximize your last day in Greece and go on a shopping spree in Thessaloniki’s shopping center, the lively Tsimiski Street. Browse for souvenirs to remind you of your wonderful journey in Greece. Discover boutiques with stylish fashion choices to upgrade your wardrobe.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

Treat yourself to a delightful dinner at Millet, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Agora Ouzeri? It's another excellent option with a diverse menu.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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