11-Day Greece Self-Drive Road Trip With Itinerary from Kavala Prefecture to Thessaloniki, Ioannina, Trikala, Larissa, and Nea Moydania

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Photo of aerial view the city of Kavala in northern Greek, ancient aqueduct Kamares, homes and beaches.
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Explore the best of Greece on a remarkable 11-day road trip! Combine exploration with relaxation on a self-drive tour featuring Kavala Prefecture, Lydia, Krinides, Thessaloniki, Ioannina, Mesopotamo, Kanallaki, Neo Bizani, Perama, Metsovo, Kastraki, Trikala, Kato Palaiokarya, Larissa, Neos Panteleimonas, Litochoro, Katerini, Nea Moydania, Nea Kerdylia, and Rodolivos.

This perfectly planned road trip itinerary takes you through some of the best places to see in Greece. You will spend 2 nights in Kavala Prefecture, 2 nights in Thessaloniki, 3 nights in Ioannina, 1 night in Trikala, 1 night in Larissa, and 1 night in Nea Moydania. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Kavala Prefecture, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Kavala Prefecture, Lydia, Krinides, Thessaloniki, Ioannina, Mesopotamo, Kanallaki, Neo Bizani, Perama, Metsovo, Kastraki, Trikala, Kato Palaiokarya, Larissa, Neos Panteleimonas, Litochoro, Katerini, Nea Moydania, Nea Kerdylia, and Rodolivos, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
Drop-off: 10:00

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Day 1

Day 1

  • Kavala - Arrival day
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  • Kavala Fort
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Your road trip adventure in Greece begins as soon as you reach Kavala Prefecture and pick up your car. You’ll stay here for 1 night and explore what to see in Kavala Prefecture, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Kavala Prefecture is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Kavala Prefecture. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Greece. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Kavala Prefecture, it's often a good idea to reserve a table in advance.

Raise a toast to the start of your 11-day road trip in Greece!

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Day 2

Day 2

  • Kavala
  • Thessaloniki
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Drive 180 km, 2 hours 56 min

  • Faliro Park
  • Holy Baptistery of Saint Lydia of Philippi
  • Archaeological Museum of Philippi
  • Ancient theatre of Philippi
  • More

Experience an unparalleled adventure on day 2 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 3 places, which are Kavala Prefecture, Lydia, and Krinides. At the end of the day, you will retreat to the hotel of your choice in Thessaloniki, where will spend 2 nights.

At the end of the day, you will drive to Thessaloniki, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Thessaloniki. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Get a good night's sleep and look forward to another great day on the road in Greece!

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Day 3

Day 3

  • Thessaloniki
  • More

Drive 9 km, 1 hour 12 min

  • The Umbrellas by Zongolopoulos
  • White Tower of Thessaloniki
  • Arch of Galerius
  • Atatürk Museum
  • Heptapyrgion of Thessalonica
  • More

You’ll stay in Thessaloniki for 1 night.

Throughout the day, make sure to take breaks to appreciate the surroundings.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Greece. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Raise your glass to another unforgettable day in Greece!

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Day 4

Day 4

  • Thessaloniki
  • Ioannina
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Drive 263 km, 3 hours 19 min

  • Kapani
  • Agias Sofias Square
  • Aristotelous Square
  • More

On day 4 of your road trip in Greece, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Thessaloniki are on today's agenda. In the evening, you’ll end up in Ioannina, where you will stay for 3 nights.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Ioannina. Ioannina offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Ioannina is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Ioannina.

Savor another day of unforgettable experiences in Greece!

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Day 5

Day 5

  • Ioannina
  • More

Drive 219 km, 3 hours 21 min

  • Arta's Bridge
  • Necromanteion of Acheron
  • Αcheron Springs
  • More

Wake up to day 5 of your road trip in Greece. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Mesopotamo and Kanallaki. With 2 nights to stay in Ioannina, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

When you’re done exploring for the day, you’ll return to Ioannina and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ioannina, it's often a good idea to reserve a table in advance.

Celebrate another amazing day of your road trip adventure in Greece!

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Day 6

Day 6

  • Ioannina
  • More

Drive 38 km, 1 hour 18 min

  • Vrellis Greek History Museum (Wax Museum)
  • The Clock Tower of Ioannina
  • Ioannina Castle
  • Ich Kale Acropolis of Ioannina
  • Cave of Perama
  • More

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Greece. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Ioannina. Enjoy a satisfying meal that will recharge you for tonight's adventures.

As the sun sets, rest up and recharge for the next leg of your road trip in Greece.

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Day 7

Day 7

  • Ioannina
  • Trikala
  • More

Drive 145 km, 3 hours 20 min

  • Metsovo square
  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Monastery of Varlaam
  • Meteora
  • More

Your itinerary for day 7 of your road trip in Greece includes 2 stops and features some of the highlights of Metsovo and Kastraki. At the end of the day, enjoy the comforts of a top-rated hotel in Trikala, where you'll spend 1 night.

Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Ioannina.

When you’re done exploring for the day, you’ll drive to your hotel in Trikala. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Trikala's most popular restaurants, and connect with friendly locals for a true cultural experience.

Raise your glass to another unforgettable day in Greece!

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Day 8

Day 8

  • Trikala
  • Larissa
  • More

Drive 119 km, 2 hours 11 min

  • Trikala City Center Square
  • Central Bridge
  • Κέντρο Έρευνας - Μουσείο Τσιτσάνη
  • Matsopoulos Park
  • The arch bridge waterfall of Paleokaria
  • More

On day 8 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 2 destinations, including Trikala and Kato Palaiokarya. When you’re not sightseeing, take time to relax at your chosen hotel in Larissa, where you’ll be staying for 1 night.

Throughout the day, make sure to take breaks to appreciate the surroundings.

At the end of the day, you will drive to Larissa, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Larissa's best restaurants.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Greece.

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Day 9

Day 9

  • Larissa
  • Nea Moydania
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Drive 244 km, 3 hours 28 min

  • Byzantine Castle of Platamon
  • Monastery of St Dionysios in Olympus
  • Katerini Municipal Park
  • Lazaristes Monastery
  • More

Dive into day 9 of your remarkable road trip in Greece. Today you'll explore 3 destinations, including Neos Panteleimonas, Litochoro, and Katerini. At the end of the day, you’ll unwind at one of the finest accommodations in Nea Moydania, where you'll spend 1 night.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Nea Moydania. Nea Moydania offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Nea Moydania, it's often a good idea to reserve a table in advance.

Raise your glass and celebrate another amazing day of your road trip in Greece!

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Day 10

Day 10

  • Nea Moydania
  • Kavala
  • More

Drive 241 km, 3 hours 22 min

  • Thermi Dam
  • Noesis
  • Lion of Amphipolis
  • Virgin Mary Eikosifoinissa Holy Convent
  • More

Experience an unparalleled adventure on day 10 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Nea Kerdylia and Rodolivos. At the end of the day, you will retreat to the hotel of your choice in Kavala Prefecture, where will spend 1 night.

When you’re done exploring for the day, you’ll drive to your hotel in Kavala Prefecture. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Kavala Prefecture. Enjoy a relaxing evening as you savor delicious local cuisine.

Relax and look forward to more memorable moments to come!

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Day 11

Day 11

  • Kavala - Departure day
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  • Τουριστική Επιχείρηση Καβάλας
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Day 11 of your road trip in Greece is your departure day. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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