12-Day Greece Self-Drive Road Trip With Itinerary from Athens traveling north to Chalkida, Trikala, Thessaloniki, Ioannina, and Patras
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Explore the best of Greece on a 12-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Athens, Chalkida, Thermopyles, Gorgopotamos, Trikala, Kato Palaiokarya, Kastraki, Thessaloniki, Ioannina, Perama, Neo Bizani, Patras, and Kallithea. This road trip itinerary in Greece seamlessly combines exploration with relaxation.
This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 4 nights in Athens, 1 night in Chalkida, 2 nights in Trikala, 2 nights in Thessaloniki, 1 night in Ioannina, and 1 night in Patras. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Athens, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. Acropolis Of Athens and Parthenon are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Acropolis Museum, learn more about the unique Stavros Niarchos Foundation Cultural Center, and immerse yourself in the vibrant atmosphere of White Tower Of Thessaloniki.
As you hit the open road and drive through Athens, Chalkida, Thermopyles, Gorgopotamos, Trikala, Kato Palaiokarya, Kastraki, Thessaloniki, Ioannina, Perama, Neo Bizani, Patras, and Kallithea, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.
Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!
Itinerary summary
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Day 1
- Athens - Arrival day
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- Syntagma Square
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Your road trip adventure in Greece begins as soon as you reach Athens and pick up your car. You’ll stay in Athens for 3 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.
Athens is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Syntagma Square, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Athens. Make yourself at home and enjoy some downtime before heading out again.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Athens, it's often a good idea to reserve a table in advance.
Don’t miss out on dining at Zampano, a top-rated dining destination in Athens. If you're in the mood to try something new, consider Rosalia, another top spot with a mouthwatering menu. You might also want to secure a reservation at NJV Athens Plaza. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Athens this evening.
Unwind after your meal by stepping into Mayros Gatos. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Kuko's The Bar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Revolt Street Bar, another top-rated bar in the area.
Raise a toast to the start of your 12-day road trip in Greece!
Day 2
- Athens
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Drive 8 km, 1 hour 7 min
- National Archaeological Museum of Athens
- Technopolis City of Athens
- Odeon of Herodes Atticus
- Acropolis of Athens
- Parthenon
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Day 2 offers a multitude of experiences. You will stay in Athens for 2 nights more, offering you enough time to explore at a relaxed pace.
Immerse yourself in Athens’s rich culture with today's sightseeing itinerary. Start your journey at National Archaeological Museum Of Athens. This heritage-rich museum is sure to ignite your curiosity. Next, dive into the eye-catching features of Technopolis City Of Athens, a must-visit cultural center in the city.
In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Odeon Of Herodes Atticus, an interesting archeological site. For a change of scene, check out Acropolis Of Athens, known for its historic features.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Greece is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As dinnertime approaches, it's time to head out for a bite to eat in Athens. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Dive into a culinary adventure like no other in Athens by booking a table at Hytra. This popular restaurant holds 1 Michelin star and offers an exceptional menu of modern cuisine. For another culinary dining option, venture to Spondi, celebrated for its delectable french menu. This acclaimed 1-star Michelin-recipient consistently leaves guests satisfied, ensuring an essential addition to your holiday itinerary. Seeking an alternative? Discover The Zillers, a top local restaurant known for its tantalizing contemporary and greek menu. With a 1-star Michelin recognition, it promises an exceptional dining experience not to be missed.
Extend your evening after a delightful meal by visiting Tiki Bar Athens, which offers the perfect atmosphere for a night out. Moreover, Brettos is another popular option for a drink or two. Likewise, Luxus Bar Bistro also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.
As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Greece.
Day 3
- Athens
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Drive 9 km, 1 hour 3 min
- Philopappos Hill
- Acropolis Museum
- Temple of Olympian Zeus
- Athens National Garden
- Benaki Museum
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Day 3 of your road trip across Greece promises a magnificent time exploring Athens. You have 1 night left in Athens. Take the opportunity to experience more of the best attractions and activities in the city.
Enjoy the perfect balance of relaxation and exploration in Athens today. One of the most captivating attractions included on the itinerary is Philopappos Hill. This standout park will help you start your sightseeing on top. Then, take a leisurely stroll to Acropolis Museum and learn what makes this instagrammable museum unique.
Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the well-known Temple Of Olympian Zeus. After exploring the archeological site, head to National Garden Of Athens. This well-known botanical garden is a highlight in Athens. Lastly, don’t forget to check out the up-and-coming Benaki Museum. Enjoy exploring this incredible museum at your own pace.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Greece is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
Indulge in a memorable dining experience at one of Athens's most popular restaurants, and connect with friendly locals for an authentic adventure.
Enjoy a delicious meal at Cookoovaya, a highly-rated dining destination in Athens. If you're eager to try something different, consider Karamanlidika, another top spot with a tantalizing menu. You might also want to secure a reservation at Estiatorio Auli. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Athens this evening.
After your meal, keep the night alive at a bar like Kazu Cafe-bar, known for its lively atmosphere. Upupa Epops - The Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Gazarte offers an excellent atmosphere for those looking to amp up the evening.
Take some time to reflect on your day and savor another beautiful night in Greece.
Day 4
- Athens
- Chalkida
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Drive 82 km, 1 hour 32 min
- Monastiraki Square
- Roman Forum of Athens (Roman Agora)
- Hadrian's Library
- Ancient Agora of Athens
- Temple of Hephaestus
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Dive into day 4 of your remarkable road trip in Greece. Today you will explore Athens, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Chalkida. You’ll stay here for 1 night.
Prepare for a day full of fun adventures, picturesque spots, and history-rich sites. When you’re ready, kick off your sightseeing adventure at Monastiraki Square 6. This well-known public square is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Roman Agora, one of the city’s best highlights.
Next, check out Hadrian's Library, one of the most increasingly popular places to see in Athens. This archeological site is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Ancient Agora Of Athens. Wander around and soak in the respected atmosphere this archeological site offers. Then, head to Temple Of Hephaestus, a top-rated archeological site that adds another dimension to your day.
When you’re done exploring for the day, you’ll drive to your hotel in Chalkida. Check in and spend some time relaxing before you head out to tour the city.
Indulge in a memorable dining experience at one of Chalkida's most popular restaurants, and connect with friendly locals for an authentic adventure.
Enjoy a lovely meal at Stavento, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, 25 DRAMIA is another top choice with a popular menu. You could also check for a table at Psistaria Apostoloy. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Chalkida tonight.
Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Boheme Cafe Bar stands out as an excellent choice for a post-dinner cocktail. Alternatively, Galatiko Chorio offers an ideal atmosphere to enjoy the pleasures of the night. Euan is also a great option that provides a perfect setting for a relaxing evening.
Celebrate another amazing day of your road trip adventure in Greece!
Day 5
- Chalkida
- Trikala
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Drive 291 km, 3 hours 53 min
- Waterfront of Chalkida
- Karababa Castle
- Memorial of Leonidas and 300 Spartans
- Gorgopotamos bridge
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Experience an unparalleled adventure on day 5 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 3 vibrant destinations - Chalkida, Thermopyles, and Gorgopotamos. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Trikala. You will spend 2 nights here for some well-deserved relaxation.
Chalkida is home to plenty of attractions that offer family-friendly attractions, romantic experiences, and breathtaking views! Start at Chalkida's Seaside, a beloved boardwalk that is worthwhile a visit in the city. Nearby, you’ll find Karababa Castle, enchanting visitors with its majestic appeal. Continue your exploration at Memorial To Leonidas And 300 Spartans. This war memorial is one of the city’s most underrated spots.
Enjoy the freedom of exploring Chalkida at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Gorgopotamos Bridge.
At the end of the day, you will drive to Trikala, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
After a day of adventure, treat yourself to an exquisite dinner at one of Trikala's best restaurants.
Treat yourself to a wonderful meal at ALVEO, a top-rated dining spot in Trikala. If you're in the mood for something new, try Trikala Fortress, another premier location with a delectable menu. You might also want to book a table at Palia Istoria. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Trikala.
Continue your lively evening at Soyita Art Cafe, a perfect place for winding down or revving up the night, depending on which mood you’re in. Factory Café is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, The Love Shake ensures a night out tailored to your taste.
Savor another day of unforgettable experiences in Greece!
Day 6
- Trikala
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Drive 59 km, 1 hour 43 min
- Byzantine Castle of Trikala
- Trikala City Center Square
- Central Bridge
- Matsopoulos Park
- The arch bridge waterfall of Paleokaria
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On day 6 of your road trip, you’ll start and end your day in Trikala, where you'll stay for 1 night more.
Get ready for a day filled with fun adventures, romantic experiences, and scenic views in the charming city of Trikala. Your adventure starts at Byzantine Castle Of Trikala, a frequently visited local hot spot. Another notable attraction to explore is Trikala City Center Square. This beloved public square is known for its enchanting appeal.
After soaking in the highlights of these sights, take some time to wander Trikala's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Central Bridge. This romantic public square offers a fascinating experience that many visitors find memorable. Matsopoulos Park is also worth visiting, along with Stone Bridge And Waterfall Of Palaiokarya. These standout landmarks offer unique experiences that add to the day’s enjoyment.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Trikala.
As you explore more of Trikala, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Treat yourself to a wonderful meal at Gyrománia, a top-rated dining spot in Trikala. If you're in the mood for something new, try Tavern Katogi, another premier location with a delectable menu. You might also want to book a table at Pans and Grills. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Trikala.
Keep the evening going at Bittersweet Cocktail Bar, a great choice for enjoying the after-dinner hours with a drink. You could also go to Krypti Bar, which offers a similarly pleasant setting and great drinks.
As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Greece.
Day 7
- Trikala
- Thessaloniki
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Drive 256 km, 4 hours 19 min
- Meteora
- The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
- Monastery of Varlaam
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On day 7 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 1 destination, Kastraki. When you’re not sightseeing, take time to relax at your selected hotel in Thessaloniki, where you’ll be staying for 2 nights.
Meteora is must-visit monastery and a great starting point for the day. Next, continue your journey to Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour, an often recommended monastery, located just a leisurely stroll away. Next, head to Monastery Of Varlaam, a historic monastery, also available for your discovery today.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Thessaloniki. Thessaloniki offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Thessaloniki. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Enjoy a delicious meal at Kitchen Bar, a top-rated dining destination in Thessaloniki. If you're in the mood to try something new, consider The Greek, another top spot with a mouthwatering menu. You might also want to secure a reservation at Phanós. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Thessaloniki this evening.
Unwind after your meal by stepping into Beetle Bar. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Vogatsikou 3 offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Souel, another top-rated bar in the area.
Raise your glass to another unforgettable day in Greece!
Day 8
- Thessaloniki
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Drive 10 km, 1 hour 3 min
- Heptapyrgion of Thessalonica
- Atatürk Museum
- Arch of Galerius
- White Tower of Thessaloniki
- The Umbrellas by Zongolopoulos
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On day 8 of your road trip, you will have an entire day to explore Thessaloniki. You’ll stay in Thessaloniki for 1 night and discover all the best things to see and do in the area.
Thessaloniki is home to plenty of attractions that offer fun adventures, scenic views, and picturesque spots! Start at Heptapyrgion Of Thessaloniki, an increasingly popular castle that is worthwhile a visit in the city. Nearby, you’ll find Atatürk Museum, enchanting visitors with its instagrammable appeal. Continue your exploration at Arch Of Galerius And Rotunda. This monument is one of the city’s most locally renowned spots.
Enjoy the freedom of exploring Thessaloniki at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit White Tower Of Thessaloniki. After exploring the monument, head to the interesting The Umbrellas Sculpture By Zogolopoulos. This art installation will wrap up today’s self-guided sightseeing tour in the city.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Greece is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Thessaloniki. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.
Enjoy a delicious meal at Mamalouka, a top-rated dining destination in Thessaloniki. If you're in the mood to try something new, consider Clochard, another top spot with a mouthwatering menu. You might also want to secure a reservation at Sofi's House Restaurant. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Thessaloniki this evening.
After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Castra- All Day Terrace Bar, a well-loved spot among locals and tourists. Or, head to Barbaben - Bar/ba/ben. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Apallou, another top-rated place in the area.
As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Greece.
Day 9
- Thessaloniki
- Ioannina
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Drive 263 km, 3 hours 19 min
- Kapani
- Agias Sofias Square
- Aristotelous Square
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On day 9 of your road trip in Greece, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Thessaloniki. In the evening, you’ll end up in Ioannina, where you will stay for 1 night.
Set out on a day brimming with family-friendly attractions, picturesque spots, and historic treasures. Start at the interesting Kapani, an instagrammable market in Thessaloniki. Next, go to Agias Sofias Square.
After visiting Kapani and Agias Sofias Square, take time to explore Thessaloniki's streets and absorb its charm. Continue your sightseeing by heading to Aristotelous Square. This romantic public square offers a unique experience.
When you’re done exploring for the day, you’ll drive to your hotel in Ioannina. Check in and spend some time relaxing before you head out to tour the city.
As you explore more of Ioannina, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Enjoy a delicious meal at To Dodeka Cafe Bar, a highly-rated dining destination in Ioannina. If you're eager to try something different, consider Mustagogia, another top spot with a tantalizing menu. You might also want to secure a reservation at Accademia Del Panino. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Ioannina this evening.
To truly maximize your evening out, consider visiting ⚜ V E D E M A ⚜ after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Hogwarts Tales And Spirits, another bar with an inviting ambiance. Similarly, Chevalier also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.
As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Greece.
Day 10
- Ioannina
- Patras
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Drive 235 km, 3 hours 23 min
- Litharitsia park
- Ioannina Castle
- Ich Kale Acropolis of Ioannina
- Cave of Perama
- Vrellis Greek History Museum (Wax Museum)
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Embark on another extraordinary experience on day 10 of your road trip in Greece. Today, you will make 3 stops and experience some of the highlights of Ioannina, Perama, and Neo Bizani. At the end of the day, you will enjoy the comforts of a top-rated hotel in Patras, which will be your home away from home for 1 night.
Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Ioannina allows for both. Start by heading to Litharitsia Park. This frequently visited park provides an insightful glimpse into the city's identity. Next, discover Ioannina Castle, a history-steeped castle, promising a delightful encounter.
Continue your sightseeing with a visit to Ic Kale Acropolis Of Ioannina, an increasingly popular archeological site. When you’re done, don’t forget to make a stop at the increasingly popular Cave Of Perama. Round off your day at Moyseio Ellinikis Istorias Payloy Vrelli, another gem in Ioannina with detailed features to discover.
At the end of the day, you will drive to Patras, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As dinnertime approaches, it's time to head out for a bite to eat in Patras. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Treat yourself to a delightful dinner at Tag, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Bianco? It's another excellent option with a diverse menu. Consider reserving a table at Carousello as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Patras.
Continue your evening by exploring the vibrant nightlife scene at Sofita, a prime destination for a thrilling night out. Also, don’t forget to check out Charama Therino, a bar that offers unique local touches. Likewise, Notos provides an excellent alternative for a fun evening.
Relax and reminisce about your day in Greece and look forward to more memorable moments to come!
Day 11
- Patras
- Athens
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Drive 224 km, 2 hours 47 min
- Stavros Niarchos Foundation Cultural Center
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Dive into day 11 of your remarkable road trip in Greece. Today you will explore Kallithea, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Athens. You’ll stay here for 1 night.
Enjoy the perfect balance of relaxation and exploration in Patras today. One of the most famous attractions included on the itinerary is Stavros Niarchos Foundation Cultural Center. This breathtaking cultural center will help you start your sightseeing on top.
Throughout the day, make sure to take breaks to appreciate the surroundings.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Athens. Athens offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Athens. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Savor the flavors at Beer Tales, a top pick for dinner tonight. Alternatively, Oinomageireio Epirus (est.1898) beckons with its unique menu offerings. Also, consider To Kafeneio. With its consistent customer satisfaction, it’s an excellent option for dining in Athens tonight.
Explore the vibrant nightlife at Ipitou The Bar after your meal, a hub for lively evenings and memorable moments. Or, head to Lot 51 for a great selection of flavorful drinks and a charming setting. Furthermore, Klōstḗrion is perfect for those looking to extend their night with a touch of local flavor.
Take some time to reflect on your day and savor another beautiful night in Greece.
Day 12
- Athens - Departure day
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- Self-managed Park Navarinou
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Day 12 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Athens before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, we recommend visiting Self-managed Park Navarinou, a visually striking park before you head out.
Make the most of your final day in Greece by visiting Athens’s iconic markets and shopping establishments in the buzzing Kolonaki. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Greece. You can also browse through boutiques for stylish fashion choices.
Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Athens.
If you're in the mood to try something new, consider Ama Lachei, another top spot with a mouthwatering menu.
You’ll then say farewell to Athens. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!
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