Two-Week Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling south to Kalambaka, Athens, Nafplio, Patras, and Ioannina

1 / 85
Photo of Saint Paul cathedral in Thessaloniki, Greece.
Perfect travel plans
Everything included
Fully customizable

Description

Included

Flights
Hotel
Select dates
Car rental
Select dates
Tours & tickets
Select dates
Travel plan
From A to Z
Travel agent
24/7 fast service

Description

Experience the freedom of the open road on an unforgettable 15-day road trip in Greece! Embark on a self-drive tour that caters to every traveler, featuring destinations like Thessaloniki, Kastraki, Kalambaka, Athens, Delphi, Lavreotiki, Nafplio, Mykines, Lighourio, Antirio, Patras, Olympia, Ioannina, Zagori, Mikro Papigko, Vikos, and Vergina.

This perfectly planned road trip itinerary takes you through some of the best places to see in Greece. You will spend 3 nights in Thessaloniki, 1 night in Kalambaka, 4 nights in Athens, 2 nights in Nafplio, 2 nights in Patras, and 2 nights in Ioannina. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. Acropolis Of Athens and Parthenon are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Thessaloniki, Kastraki, Kalambaka, Athens, Delphi, Lavreotiki, Nafplio, Mykines, Lighourio, Antirio, Patras, Olympia, Ioannina, Zagori, Mikro Papigko, Vikos, and Vergina, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

Read more

Travel details

Set your travel details to find the best price

Flights

Round trip
Round trip
Travel dates

Travelers

Rooms

Flights

Compare and choose from the best flights to Thessaloniki

Car

Choose from the best car rental deals or see all options

Driver’s age is 30 - 65
I live in
Pick-up: 10:00
Drop-off: 10:00

Personalize your itinerary

Customize tours under each day and destination

Day 1

Day 1

  • Thessaloniki - Arrival day
  • More
  • Ladadika
  • More

Welcome to Thessaloniki, the perfect starting point for your road trip in Greece! Pick up your rental car and let the adventure begin. You will spend 2 nights discovering what to see in Thessaloniki before embarking on the next leg of your journey.

Thessaloniki is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Thessaloniki. Check-in typically starts around 2 to 4 PM at hotels in Greece. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Raise a toast to the start of your 15-day road trip in Greece!

Read more
Day 2

Day 2

  • Thessaloniki
  • More

Drive 6 km, 52 min

  • The Umbrellas by Zongolopoulos
  • White Tower of Thessaloniki
  • Agias Sofias Square
  • Aristotelous Square
  • Tsimiski Street
  • More

You have 1 night left in Thessaloniki. Take the opportunity to experience more of the best attractions and activities in the city.

Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Thessaloniki.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Greece. You can explore and select activities under each day of your itinerary.

For an unforgettable shopping experience, visit Tsimiski Street, the top shopping destination in Thessaloniki. Browse local boutique shops and stores, each offering delightful surprises. Find unique souvenirs or items to take home. After shopping, explore what Tsimiski Street has to offer, including attractions, essential services, and vibrant community activities.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Thessaloniki. Enjoy a relaxing evening as you savor delicious local cuisine.

Take some time to reflect on your day and savor another beautiful night in Greece.

Read more
Day 3

Day 3

  • Thessaloniki
  • Meteora
  • More

Drive 244 km, 3 hours 27 min

  • Holy Monastery of Rousanos - Saint Barbara
  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Monastery of St Stephan
  • Meteora
  • More

Your itinerary for day 3 of your road trip in Greece includes 2 stops and features some of the highlights of Kastraki and Kalambaka. At the end of the day, enjoy the comforts of a top-rated hotel in Kalambaka, where you'll spend 1 night.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Kalambaka. Kalambaka offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Kalambaka. Enjoy a relaxing evening as you savor delicious local cuisine.

Get a good night's sleep and look forward to another great day on the road in Greece!

Read more
Day 4

Day 4

  • Meteora
  • Athens
  • More

Drive 357 km, 4 hours 13 min

  • Natural History Museum of Meteora and Mushroom Museum
  • Monastery of the Holy Trinity at Meteora
  • Main Observation Deck of Meteora
  • Monastery of Varlaam
  • More

On day 4 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 2 destinations, including Kalambaka and Kastraki. When you’re not sightseeing, take time to relax at your chosen hotel in Athens, where you’ll be staying for 4 nights.

At the end of the day, you will drive to Athens, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Athens, it's often a good idea to reserve a table in advance.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Greece.

Read more
Day 5

Day 5

  • Athens
  • More

Drive 365 km, 4 hours 56 min

  • Temple of Apollo
  • Treasury of Athenians
  • Delphi Archaeological Museum
  • Tholos of Delphi
  • More

On day 5 of your road trip in Greece, you’ll start and end your day in Athens, but spend the day exploring what’s beyond the city. Since you still have 3 nights to spend in Athens, there’s no need to rush. Experience Delphi to the fullest today with this curated day itinerary.

When you’re done exploring for the day, you’ll return to Athens and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Athens, it's often a good idea to reserve a table in advance.

Head back to your accommodation in Athens and get some rest to prepare for another magical day of your road trip in Greece.

Read more
Day 6

Day 6

  • Athens
  • More

Drive 4 km, 1 hour 2 min

  • Parthenon
  • Acropolis of Athens
  • Acropolis Museum
  • Plaka
  • Monastiraki
  • More

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Greece. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Athens. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Relax and recharge in preparation for another adventurous day in Greece!

Read more
Day 7

Day 7

  • Athens
  • More

Drive 153 km, 2 hours 25 min

  • Archaeological Site of Sounion
  • Temple of Poseidon
  • Archaeological Museum of Lavrion
  • More

On day 7 of your road trip, you’ll start and end your day in Athens, where you have 1 night left to stay.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Athens.

After a day of adventure, treat yourself to an exquisite dinner at one of Athens's best restaurants.

Raise your glass to another unforgettable day in Greece!

Read more
Day 8

Day 8

  • Athens
  • Nafplio
  • More

Drive 147 km, 3 hours 49 min

  • Nafplio Port
  • Archaeological Museum of Nafplion
  • Church of Saint Spyridon
  • Akronauplía
  • Palamidi
  • More

Dive into day 8 of your remarkable road trip in Greece. Today you'll explore 1 destination, including Nafplio. At the end of the day, you’ll unwind at one of the finest accommodations in Nafplio, where you'll spend 2 nights.

When you’re done exploring for the day, you’ll drive to your hotel in Nafplio. Check in and relax before you head out to tour the town.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Nafplio. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Take some time to reflect on your day and savor another beautiful night in Greece.

Read more
Day 9

Day 9

  • Nafplio
  • More

Drive 98 km, 2 hours 4 min

  • Archeological Museum of Mycenae
  • Mycenae
  • Treasury of Atreus" or "Tomb of Agamemnon
  • Archaeological Site of the Sanctuary of Asclepius at Epidaurus
  • Ancient Theatre at the Asclepieion of Epidaurus
  • More

Wake up to day 9 of your road trip in Greece. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Mykines and Lighourio. With 1 night to stay in Nafplio, we encourage you to seize the day and discover the unexplored beauty of the town’s surroundings!

When you’re done exploring for the day, you’ll return to Nafplio and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Nafplio. Enjoy a relaxing evening as you savor delicious local cuisine.

Get a good night's sleep and look forward to another great day on the road in Greece!

Read more
Day 10

Day 10

  • Nafplio
  • Patras
  • More

Drive 198 km, 3 hours 3 min

  • Rion-Antirion Bridge
  • Patras' South Park - Notio Parko Patras
  • Church of Agios Andreas
  • St Nicholas Stairway
  • King George Ι Square (Patras)
  • More

On day 10 of your road trip in Greece, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Antirio and Patras are on today's agenda. In the evening, you’ll end up in Patras, where you will stay for 2 nights.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Patras. Patras offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Patras is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Patras.

Relax and look forward to more memorable moments to come!

Read more
Day 11

Day 11

  • Patras
  • More

Drive 213 km, 4 hours 15 min

  • Archaeological Site of Olympia
  • Temple of Hera
  • Άλσος Ολυμπιακής Εκεχειρίας
  • Parking Olimpia
  • Museum of the History of the Olympic games of antiquity
  • More

On day 11 of your road trip, you'll get the chance to experience Olympia. At the end of the day, you'll drive back to Patras, where you still have 1 night left to stay.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Patras.

Indulge in a memorable dining experience at one of Patras's most popular restaurants, and connect with friendly locals for a true cultural experience.

Celebrate another amazing day of your road trip adventure in Greece!

Read more
Day 12

Day 12

  • Patras
  • Ioannina
  • More

Drive 220 km, 3 hours

  • Silversmithing Museum
  • Ich Kale Acropolis of Ioannina
  • Ioannina Castle
  • Litharitsia park
  • The Clock Tower of Ioannina
  • More

Experience an unparalleled adventure on day 12 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Ioannina. At the end of the day, you will retreat to the hotel of your choice in Ioannina, where will spend 2 nights.

At the end of the day, you will drive to Ioannina, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Ioannina's most popular restaurants, and connect with friendly locals for a true cultural experience.

Relax and recharge in preparation for another adventurous day in Greece!

Read more
Day 13

Day 13

  • Ioannina
  • More

Drive 134 km, 3 hours 15 min

  • Vikos National Park
  • Papingo Rock Pools
  • Voidomatis Springs
  • Angastromeni Springs
  • More

On day 13 of your road trip, you’ll start and end your day in Ioannina, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate city, including Zagori, Mikro Papigko, and Vikos.

When you’re done exploring for the day, you’ll return to Ioannina and your accommodation.

Ioannina is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Ioannina.

Relax and look forward to more memorable moments to come!

Read more
Day 14

Day 14

  • Ioannina
  • Thessaloniki
  • More

Drive 280 km, 3 hours 10 min

  • Polycentric Museum of Aigai (Aegae) - Main Building
  • Museum of the Royal Tombs at Aigai (Aegae)
  • Haliacmon Dam - Artificial Lake at Saint Barbara of Veria
  • More

Your itinerary for day 14 of your road trip in Greece includes 1 stop and features some of the highlights of Vergina. At the end of the day, enjoy the comforts of a top-rated hotel in Thessaloniki, where you'll spend 1 night.

When you’re done exploring for the day, you’ll drive to your hotel in Thessaloniki. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Thessaloniki's best restaurants.

As the sun sets, rest up and recharge for the next leg of your road trip in Greece.

Read more
Day 15

Day 15

  • Thessaloniki - Departure day
  • More
  • Arch of Galerius
  • More

Day 15 of your road trip in Greece is your departure day. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

Read more

How it works

Book your journey with Europe’s biggest travel platform—expert itineraries, instant confirmation, and full flexibility with 24/7 support.

Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

Similar travel packages

Discover other popular vacations in Greece

Link to appstore phone
Install Europe’s biggest travel app

Download Europe’s biggest travel marketplace to your phone to manage your entire trip in one place

Scan this QR code with your phone camera and press the link that appears to add Europe’s biggest travel marketplace into your pocket. Enter your phone number or email address to receive an SMS or email with the download link.