4-Day Greece road trip from Thessaloniki to Larissa

Your road trip adventure in Greece begins as soon as you reach Thessaloniki and pick up your car. You’ll stay in Thessaloniki for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Thessaloniki is a beautiful city with plenty to discover. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Thessaloniki. Check-in typically starts around 2 to 4 PM at hotels in Greece. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat in Thessaloniki. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Don't miss out on experiencing Kanoula, a renowned dining spot in Thessaloniki. This restaurant's rich flavors have left a lasting impression on diners. Its dedication to culinary perfection is evident in its 4.8 out of 5-star rating from 2,335 satisfied guests.

Make a reservation at rOOTS while immersing yourself in Thessaloniki. This distinguished restaurant offers imaginative dishes, with a remarkable rating of 4.7 out of 5 stars by 2,104 guests.

Discover the culinary treasures of Kitchen Bar, a beloved dining establishment within Thessaloniki. Its exquisite menu promises to tantalize your taste buds and transport you to culinary bliss. Renowned for its exceptional service, it has earned a 4.3 out of 5-star rating from 9,067 satisfied customers.

When you’ve finished your meal, Pulp is one of the best bars in Thessaloniki for an after-dinner drink. This bar is rated an average of 4.7 out of 5 stars by 1,573 customers.

Wall by Wall is another of the most popular bars in the city. This bar is rated an average of 4.5 out of 5 stars by 4,128 customers.

Alternatively, check out Loupino Restaurant. This popular place has an average rating of 4.4 out of 5 stars, as rated by 3,657 customers.

Raise a toast to the start of your 4-day road trip in Greece!

Experience an unparalleled adventure on day 2 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Thessaloniki and Larissa. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Larissa. You will spend 1 night here for some well-deserved relaxation.

Make Kapani one of your first sightseeing stops in Thessaloniki. Rated an average of 4.4 out of 5 stars by 11,618 travelers, a visit to this local attraction makes for a great introduction to the area.

Agias Sofias Square is a worthwhile attraction you can visit next. This square is a valued place of interest in the area, with an average rating of 4.6 out of 5 stars from 10,231 reviews.

Today is also the perfect opportunity to drop by White Tower of Thessaloniki. This fortified tower has been rated an average of 4.7 out of 5 stars by 51,335 visitors. Up to 290,192 people travel to this site annually.

If you’re keen to explore more, head to Arch of Galerius and Rotunda. A trip to this popular tetrapylon is also your opportunity to see if it lives up to the reputable 4.6 out of 5-star rating as given by 12,215 previous visitors.

Another top place to visit is Atatürk Museum. This house museum enjoys an average rating of 4.6 out of 5 stars from 7,650 local and international travelers.

As you’ve unraveled the marvels of Thessaloniki, it’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Larissa may take around 2 hours 6 min. Upon your arrival in Larissa, you’ll be greeted with the opportunity to do some sightseeing and exploring.

When you’re done exploring for the day, you’ll drive to Larissa, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Larissa's best restaurants.

Reserve your spot at Nonna Rossa, a popular local restaurant in Larissa. This culinary hotspot and its flavorful dishes have left a lasting impression on guests. Its dedication to culinary mastery is reflected by its 4.5 out of 5-star rating from 2,797 satisfied guests.

Make it a priority to experience Las Ramblas Coffeebar during your stay in Larissa. This popular local restaurant offers an unparalleled menu, with a rating of 4.5 out of 5 stars by 2,338 discerning guests.

Explore the culinary wonders of Mpakalógatos, a popular local gem in Larissa. Its enticing menu promises a journey through flavors that will leave a lasting impression. Renowned for its impeccable service, it boasts a 4.4 out of 5-star rating from 1,836 satisfied guests.

After dinner, visit Gossip Downtown, which is considered one of the best bars in the city of Larissa. This bar is rated an average of 4.6 out of 5 stars by 1,557 customers.

You can also enjoy drinks at a popular bar like Klímax. This bar has an average rating of 4.3 out of 5 stars by 1,734 customers.

Alternatively, locals recommend KUBRICK Pure Social “ Club ”. This bar, rated an average of 4.5 out of 5 stars by 1,128 customers, is one of the best bars in the city of Larissa.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Greece.

On day 3 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 2 destinations, Trikala and Thessaloniki. When you’re not sightseeing, take time to relax at your selected hotel in Thessaloniki, where you’ll be staying for 1 night.

After soaking in Larissa’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Trikala. Expect your car journey to take a minimum of 56 min. When you arrive in Trikala, it's time to take a break from the road.

Seize the day by visiting some of the best attractions in the area, like Matsopoulos Park. This extraordinary park has an average rating of 4.7 out of 5 stars from 8,887 visitors.

Next, make your way to Byzantine Castle of Trikala. This point of interest is rated an average of 4.6 out of 5 stars in 2,098 reviews.

While in Trikala, we also recommend a visit to Central Bridge. This sightseeing destination has been rated an average of 4.8 out of 5 stars in 2,978 reviews.

If you’re keen to explore even more, then consider a visit to Trikala City Center Square. With an average rating of 4.7 out of 5 stars by 3,972 travelers, this park is a highly recommended stop on your sightseeing around Trikala.

Set your GPS to Thessaloniki and hit the road. Expect a journey of approximately 2 hours 29 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Thessaloniki beckons with new experiences!

At the end of the day, you will drive to Thessaloniki, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Thessaloniki. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Book a table at Giok Balik, a famous dining establishment in Thessaloniki. This culinary hotspot and its appetizing cuisine have captured the hearts of food enthusiasts. Its reputation for food excellence is reflected in its 4.4 out of 5-star rating from 4,336 satisfied diners.

Another dining place you should visit in Thessaloniki is Sebriko, which boasts a variety of tasteful dishes that cater to different palates. It has earned a commendable 4.6 out of 5 stars, demonstrating the positive feedback from 2,978 satisfied customers.

Locals and visitors alike recommend Thessaloniki’s Charoupi for the delightful dining experience it gives. The establishment has garnered positive reviews for its tasty dishes, holding an admirable score of 4.6 out of 5 stars from 2,912 satisfied diners.

If you’re looking for a bar to end the evening at, many locals recommend Tribeca, claiming it’s one of the best in the city. This bar has an average rating of 4.4 out of 5 stars by 3,262 customers.

Another popular place to go for a drink is Castra- All Day Terrace Bar. This bar is rated an average of 4.5 out of 5 stars by 2,882 customers.

The Blue Cup | Creative bar is another top-rated bar where you can spend an hour or two. This bar is rated an average of 4.6 out of 5 stars by 2,254 customers.

Savor another day of unforgettable experiences in Greece!

Day 4 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Optimize your last day in Greece and go on a shopping spree in Thessaloniki’s shopping center. This bustling commercial district is conveniently located near your lodging, granting you leisure time to roam and explore its assortment of establishments.

If you love the adrenaline rush of hunting for the best offers and deals in Greece, you’re in for a treat. A variety of goods and gifts await your discovery.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!