4-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling west to Kalambaka

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Experience the freedom of the open road in Greece as you embark on an unforgettable 4-day road trip! This experience caters to every traveler, featuring destinations like Thessaloniki, Vergina, Kastraki, Kalambaka, Metsovo, Perama, and Ioannina.

This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 2 nights in Thessaloniki and 1 night in Kalambaka. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Ioannina Castle are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Museum Of The Royal Tombs At Aigai (aegae), learn more about the unique Monastery Of Varlaam, and immerse yourself in the vibrant atmosphere of Cave Of Perama.

As you hit the open road and drive through Thessaloniki, Vergina, Kastraki, Kalambaka, Metsovo, Perama, and Ioannina, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Ladadika
Museum of the Royal Tombs at Aigai (Aegae)Monastery of VarlaamMonastery of the Holy Trinity at MeteoraMain Observation Deck of MeteoraGreek Education Museum
Metsovo squareCave of PeramaThe Clock Tower of IoanninaIoannina CastleFethiye Mosque
White Tower of Thessaloniki

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Day 1

Day 1

  • Thessaloniki - Arrival day
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  • Ladadika
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Your road trip adventure in Greece begins as soon as you reach Thessaloniki and pick up your car. You’ll stay in Thessaloniki for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Thessaloniki is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ladadika, a must-see neighborhood, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Thessaloniki. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Greece. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at Kitchen Bar, an excellent option for tonight's dining. Looking for something different? The Greek offers a tantalizing alternative with its diverse menu. And don’t miss Phanós. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Thessaloniki.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Beetle Bar stands out as an excellent choice for a post-dinner cocktail. Alternatively, Vogatsikou 3 offers an ideal atmosphere to enjoy the pleasures of the night. Souel is also a great option that provides a perfect setting for a relaxing evening.

Raise a toast to the start of your 4-day road trip in Greece!

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Day 2

Day 2

  • Thessaloniki
  • Meteora
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Drive 254 km, 3 hours 40 min

  • Museum of the Royal Tombs at Aigai (Aegae)
  • Monastery of Varlaam
  • Monastery of the Holy Trinity at Meteora
  • Main Observation Deck of Meteora
  • Greek Education Museum
  • More

On day 2 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 3 destinations, Vergina, Kastraki, and Kalambaka. When you’re not sightseeing, take time to relax at your selected hotel in Kalambaka, where you’ll be staying for 1 night.

Today’s route brings family-friendly attractions, photo-friendly spots, and historic treasures. The first attraction of today is Museum Of The Royal Tombs At Aigai (aegae). This intriguing museum is an UNESCO world heritage-designated place to see in Thessaloniki. Continue your discovery at Monastery Of Varlaam, a breathtaking monastery with stories to tell.

As you stroll around Thessaloniki, take in the distinct atmosphere and learn what makes this village so unique. Maximize your sightseeing with a visit to Monastery Of The Holy Trinity At Meteora. This often recommended monastery offers a historic encounter with Thessaloniki. Next, make your way to Main Observation Deck Of Meteora to add another highlight to your day. After that, visit Greek Education Museum, an intriguing museum that’s sure to impress. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Thessaloniki.

When you’re done exploring for the day, you’ll drive to your hotel in Kalambaka. Check in and spend some time relaxing before you head out to tour the town.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Kalambaka. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Relax and recharge in preparation for another adventurous day in Greece!

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Day 3

Day 3

  • Meteora
  • Thessaloniki
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Drive 371 km, 5 hours 20 min

  • Metsovo square
  • Cave of Perama
  • The Clock Tower of Ioannina
  • Ioannina Castle
  • Fethiye Mosque
  • More

Experience an unparalleled adventure on day 3 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 3 vibrant destinations - Metsovo, Perama, and Ioannina. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Thessaloniki. You will spend 1 night here for some well-deserved relaxation.

Immerse yourself in Kalambaka’s rich culture with today's sightseeing itinerary. Start your journey at Metsovo Square. This awe-inspiring public square is sure to ignite your curiosity. Next, dive into the gorgeous features of Cave Of Perama, a must-visit cave in the town.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to The Clock Tower Of Ioannina, an increasingly popular monument. For a change of scene, check out Ioannina Castle, known for its visually striking features. We also recommend visiting Fethiye Mosque. This mosque is a must for anyone looking to experience the town to the fullest.

At the end of the day, you will drive to Thessaloniki, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Thessaloniki. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Dine in style at Mamalouka, a top recommendation for dinner tonight. Or, for a change of pace, Clochard boasts a menu that's sure to impress. Also, be sure to check out Sofi's House Restaurant. Known as a local hotspot, it’s a great choice for tonight in Thessaloniki.

After your meal, keep the night alive at a bar like Castra- All Day Terrace Bar, known for its lively atmosphere. Barbaben - Bar/ba/ben is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Apallou offers an excellent atmosphere for those looking to amp up the evening.

Get a good night's sleep and look forward to another great day on the road in Greece!

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Day 4

Day 4

  • Thessaloniki - Departure day
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  • White Tower of Thessaloniki
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Day 4 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting White Tower Of Thessaloniki, a breathtaking monument before you head out.

Maximize your last day in Greece and go on a shopping spree in Thessaloniki’s shopping center, the lively Modiano Market. Browse for souvenirs to remind you of your wonderful journey in Greece.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

Treat yourself to a delightful dinner at Enoches Bar, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try O Loytros? It's another excellent option with a diverse menu.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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