4-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling west to Kalambaka

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Explore the best of Greece on a 4-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Thessaloniki, Vergina, Kastraki, Kalambaka, Metsovo, Perama, and Ioannina. This road trip itinerary in Greece seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 2 nights in Thessaloniki and 1 night in Kalambaka. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Ioannina Castle are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Museum Of The Royal Tombs At Aigai (aegae), learn more about the unique Monastery Of Varlaam, and immerse yourself in the vibrant atmosphere of Cave Of Perama.

As you hit the open road and drive through Thessaloniki, Vergina, Kastraki, Kalambaka, Metsovo, Perama, and Ioannina, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Ladadika
Museum of the Royal Tombs at Aigai (Aegae)Monastery of VarlaamMonastery of the Holy Trinity at MeteoraMain Observation Deck of MeteoraGreek Education Museum
Metsovo squareCave of PeramaThe Clock Tower of IoanninaIoannina CastleFethiye Mosque
White Tower of Thessaloniki

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Day 1

Day 1

  • Thessaloniki - Arrival day
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  • Ladadika
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Your road trip adventure in Greece begins as soon as you reach Thessaloniki and pick up your car. You’ll stay in Thessaloniki for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Thessaloniki is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ladadika, a must-see neighborhood, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Thessaloniki. Check-in typically starts around 2 to 4 PM at hotels in Greece. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Savor the flavors at Kitchen Bar, a top pick for dinner tonight. Alternatively, The Greek beckons with its unique menu offerings. Also, consider Phanós. With its consistent customer satisfaction, it’s an excellent option for dining in Thessaloniki tonight.

After savoring a delicious meal, step into the vibrant nightlife at Beetle Bar, where the evening is just getting started. In the same way, Vogatsikou 3 offers a unique charm perfect for experiencing the local bar scene in Thessaloniki. Souel is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Raise a toast to the start of your 4-day road trip in Greece!

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Day 2

Day 2

  • Thessaloniki
  • Meteora
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Drive 254 km, 3 hours 40 min

  • Museum of the Royal Tombs at Aigai (Aegae)
  • Monastery of Varlaam
  • Monastery of the Holy Trinity at Meteora
  • Main Observation Deck of Meteora
  • Greek Education Museum
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Dive into day 2 of your remarkable road trip in Greece. Today you will explore Vergina, Kastraki, and Kalambaka, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Kalambaka. You’ll stay here for 1 night.

Enjoy the perfect balance of relaxation and exploration in Thessaloniki today. One of the most underrated attractions included on the itinerary is Museum Of The Royal Tombs At Aigai (aegae). This UNESCO world heritage-listed museum will help you start your sightseeing on top. Then, take a leisurely stroll to Monastery Of Varlaam and learn what makes this monumental monastery unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the intriguing Monastery Of The Holy Trinity At Meteora. After exploring the monastery, head to Main Observation Deck Of Meteora. This beloved observation deck is a highlight in Thessaloniki. As your day continues, stop by Greek Education Museum, known for its photogenic features.

When you’re done exploring for the day, you’ll drive to your hotel in Kalambaka. Check in and spend some time relaxing before you head out to tour the town.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Kalambaka. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Raise your glass to another unforgettable day in Greece!

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Day 3

Day 3

  • Meteora
  • Thessaloniki
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Drive 371 km, 5 hours 20 min

  • Metsovo square
  • Cave of Perama
  • The Clock Tower of Ioannina
  • Ioannina Castle
  • Fethiye Mosque
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Embark on another extraordinary experience on day 3 of your road trip in Greece. Today, you will make 3 stops and experience some of the highlights of Metsovo, Perama, and Ioannina. At the end of the day, you will enjoy the comforts of a top-rated hotel in Thessaloniki, which will be your home away from home for 1 night.

Today, you'll explore some of the most beautiful places in Kalambaka, including a public square, a cave, a monument, a castle, a mosque and much more! Start your day with a visit to Metsovo Square. This often recommended public square is a must-visit in the town. When you’re ready for your next discovery, continue to Cave Of Perama, which may be one of the most visually striking places you will experience today.

One of the best things about exploring Kalambaka on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to The Clock Tower Of Ioannina, a locally appreciated monument in the town. If you’re up for more discoveries, don’t forget to reserve some time for Ioannina Castle and Fethiye Mosque.

At the end of the day, you will drive to Thessaloniki, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Thessaloniki, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a wonderful meal at Mamalouka, a top-rated dining spot in Thessaloniki. If you're in the mood for something new, try Clochard, another premier location with a delectable menu. You might also want to book a table at Sofi's House Restaurant. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Thessaloniki.

Round off your dining experience by visiting Castra- All Day Terrace Bar, a prime location for a drink. Alternatively, explore the distinctive characteristics of Barbaben - Bar/ba/ben, a bar catering to every mood and preference. Apallou likewise offers a unique atmosphere, perfect for a memorable night out.

Relax and recharge in preparation for another adventurous day in Greece!

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Day 4

Day 4

  • Thessaloniki - Departure day
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  • White Tower of Thessaloniki
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Day 4 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at White Tower Of Thessaloniki. This top-rated monument is a popular place to see in the city.

As your final day in Greece unfolds, enjoy a last-minute shopping spree in Thessaloniki's best shopping area, Modiano Market. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Greece.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

If you're in the mood for something new, try O Loytros, another premier location with a delectable menu.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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