Travel packages in Greece

Road trips in Greece

4-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling west to Kalambaka

1 / 28

Photo of Saint Paul cathedral in Thessaloniki, Greece.

Perfect travel plans

Everything included

Fully customizable

Description

Included

Flights

Hotel

Select dates

Car rental

Select dates

Tours & tickets

Select dates

Travel plan

From A to Z

Travel agent

24/7 fast service

Description

Experience the freedom of the open road on an unforgettable 4-day road trip in Greece! Embark on a self-drive tour that caters to every traveler, featuring destinations like Thessaloniki, Vergina, Kastraki, Kalambaka, Metsovo, Perama, and Ioannina.

This perfectly planned road trip itinerary takes you through some of the best places to see in Greece. You will spend 2 nights in Thessaloniki and 1 night in Kalambaka. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Ioannina Castle are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Museum Of The Royal Tombs At Aigai (aegae), learn more about the unique Monastery Of Varlaam, and immerse yourself in the vibrant atmosphere of Cave Of Perama.

As you hit the open road and drive through Thessaloniki, Vergina, Kastraki, Kalambaka, Metsovo, Perama, and Ioannina, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

Travel details

Set your travel details to find the best price

Flights

Compare and choose from the best flights to Thessaloniki

Include flights

Car

Choose from the best car rental deals or see all options

Driver’s age is 30 - 65

I live in

Pick-up: 10:00

Drop-off: 10:00

Include car

Personalize your itinerary

Customize tours under each day and destination

Day 1

Thessaloniki - Arrival day
More

Ladadika
More

Say hello to Thessaloniki! Your exciting road trip through Greece is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Thessaloniki for 1 night before you continue your adventure!

Thessaloniki is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ladadika, a must-see neighborhood, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Thessaloniki. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Greece. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Kitchen Bar, a top-rated dining destination in Thessaloniki. If you're in the mood to try something new, consider The Greek, another top spot with a mouthwatering menu. You might also want to secure a reservation at Phanós. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Thessaloniki this evening.

After your meal, keep the night alive at a bar like Beetle Bar, known for its lively atmosphere. Vogatsikou 3 is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Souel offers an excellent atmosphere for those looking to amp up the evening.

Raise a toast to the start of your 4-day road trip in Greece!

Day 2

Thessaloniki
Meteora
More

Drive 254 km, 3 hours 40 min

Museum of the Royal Tombs at Aigai (Aegae)
Monastery of Varlaam
Monastery of the Holy Trinity at Meteora
Main Observation Deck of Meteora
Greek Education Museum
More

Experience an unparalleled adventure on day 2 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 3 places, which are Vergina, Kastraki, and Kalambaka. At the end of the day, you will retreat to the hotel of your choice in Kalambaka, where will spend 1 night.

Make time for Museum Of The Royal Tombs At Aigai (aegae), an often recommended museum that is worthwhile a visit in the village. Nearby, you’ll find Monastery Of Varlaam, enchanting visitors with its UNESCO world heritage-listed appeal. Continue your exploration at Monastery Of The Holy Trinity At Meteora. This monastery is one of the village’s most locally appreciated spots.

Enjoy the freedom of exploring Thessaloniki at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Main Observation Deck Of Meteora. After exploring the observation deck, head to the increasingly popular Greek Education Museum.

At the end of the day, you will drive to Kalambaka, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Kalambaka's best restaurants.

Relax and recharge in preparation for another adventurous day in Greece!

Day 3

Meteora
Thessaloniki
More

Drive 371 km, 5 hours 20 min

Metsovo square
Cave of Perama
The Clock Tower of Ioannina
Ioannina Castle
Fethiye Mosque
More

Your itinerary for day 3 of your road trip in Greece includes 3 stops and features some of the highlights of Metsovo, Perama, and Ioannina. At the end of the day, enjoy the comforts of a top-rated hotel in Thessaloniki, where you'll spend 1 night.

Metsovo Square leaves a lasting impression. This public square is one of the most frequently visited places to visit in Kalambaka. Next, head to Cave Of Perama, an up-and-coming cave, known for its idyllic features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to The Clock Tower Of Ioannina. This historic monument is a highly recommended experience. Nearby, you'll also find Ioannina Castle and Fethiye Mosque. Visit these for an interesting touch to your journey.

When you’re done exploring for the day, you’ll drive to your hotel in Thessaloniki. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Thessaloniki. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Mamalouka, a highly-rated dining destination in Thessaloniki. If you're eager to try something different, consider Clochard, another top spot with a tantalizing menu. You might also want to secure a reservation at Sofi's House Restaurant. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Thessaloniki this evening.

Continue your evening by exploring the vibrant nightlife scene at Castra- All Day Terrace Bar, a prime destination for a thrilling night out. Also, don’t forget to check out Barbaben - Bar/ba/ben, a bar that offers unique local touches. Likewise, Apallou provides an excellent alternative for a fun evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Greece.

Day 4

Thessaloniki - Departure day
More

White Tower of Thessaloniki
More

Day 4 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at White Tower Of Thessaloniki. This spectacular monument is a hotspot among locals.

For a last-minute shopping spree in Thessaloniki, Tsimiski Street is nearby. Enjoy a variety of retail stores, dining options, and essential services in one convenient location. Browse through boutiques to find unique and stylish fashion pieces to take home.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

Enjoy a lovely meal at Enoches Bar, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, O Loytros is another top choice with a popular menu.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

How it works

Book your journey with Europe’s biggest travel platform—expert itineraries, instant confirmation, and full flexibility with 24/7 support.

Secure your spot

Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.

Get instant confirmation

Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.

Personalize your itinerary

Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.

Easily make changes

Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.

Enjoy seamless planning

With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.

Explore with confidence

From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

Secure your spot

Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.

Get instant confirmation

Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.

Personalize your itinerary

Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.

Easily make changes

Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.

Enjoy seamless planning

With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.

Explore with confidence

From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

Similar travel packages

Discover other popular vacations in Greece

From 0

Install Europe’s biggest travel app

Download Europe’s biggest travel marketplace to your phone to manage your entire trip in one place

Scan this QR code with your phone camera and press the link that appears to add Europe’s biggest travel marketplace into your pocket. Enter your phone number or email address to receive an SMS or email with the download link.