5-Day Greece Self-Drive Road Trip With Itinerary from Ioannina traveling south to Preveza and Patras

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Photo of Ioannina lake Pamvotida in Epirus Region, Greece.
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Experience the freedom of the open road on an unforgettable 5-day road trip in Greece! Embark on a self-drive tour that caters to every traveler, featuring destinations like Ioannina, Perama, Neo Bizani, Preveza, Agios Nikitas, Fryni, Patras, Antirio, and Mesolongi.

This perfectly planned road trip itinerary takes you through some of the best places to see in Greece. You will spend 2 nights in Ioannina, 1 night in Preveza, and 1 night in Patras. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Ioannina, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. Kathisma 1 and Ioannina Castle are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Ioannina, Perama, Neo Bizani, Preveza, Agios Nikitas, Fryni, Patras, Antirio, and Mesolongi, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
Drop-off: 10:00

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Day1

Day 1

  • Ioannina - Arrival day
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  • Ioannina Castle
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Your road trip adventure in Greece begins as soon as you reach Ioannina and pick up your car. You’ll stay here for 1 night and explore what to see in Ioannina, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Ioannina is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ioannina Castle. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Ioannina. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ioannina, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at To Dodeka Cafe Bar, a top-rated dining spot in Ioannina. If you're in the mood for something new, try Mustagogia, another premier location with a delectable menu. You might also want to book a table at Accademia Del Panino. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Ioannina.

After enjoying a fulfilling meal, continue your evening at ⚜ V E D E M A ⚜, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Hogwarts Tales And Spirits offers a welcoming atmosphere for easing into the nightlife. Similarly, Chevalier provides an excellent environment for a relaxed and enjoyable evening.

Raise a toast to the start of your 5-day road trip in Greece!

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Day2

Day 2

  • Ioannina
  • Perama
  • Neo Bizani
  • Preveza
  • More

Drive 111 km, 2 hours 5 min

  • Cave of Perama
  • Museum "Arslan Pasha"
  • Ich Kale Acropolis of Ioannina
  • Silversmithing Museum
  • Vrellis Greek History Museum (Wax Museum)
  • More

Your itinerary for day 2 of your road trip in Greece includes 3 stops and features some of the highlights of Perama, Ioannina, and Neo Bizani. At the end of the day, enjoy the comforts of a top-rated hotel in Preveza, where you'll spend 1 night.

Enjoy all that Museum "arslan Pasha" has to offer. This is an up-and-coming sightseeing destination you should not miss. Another must-see is Ic Kale Acropolis Of Ioannina, an up-and-coming archeological site in Ioannina.

When you’re ready for the next sight, head to Silversmithing Museum Of Ioannina.

Perama welcomes you with a multitude of unique vacation experiences.

Cave Of Perama is an increasingly popular cave we recommend visiting today. Discover its scenic features before continuing your self-guided tour.

Embrace the thrill of the open road as you wave goodbye to Ioannina and set your GPS to Neo Bizani. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 22 min. Upon reaching Neo Bizani, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Moyseio Ellinikis Istorias Payloy Vrelli is an intriguing museum we recommend visiting today. Discover its detailed features before continuing your self-guided tour.

When you’re done exploring for the day, you’ll drive to your hotel in Preveza. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Preveza's most popular restaurants, and connect with friendly locals for a true cultural experience.

Make sure to reserve a table at Ano Vlanto (Ano Vlanto), an iconic dining spot in Preveza. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ventura Tavern, a popular restaurant in Preveza. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Monolithi Beach Bar, a hidden gem nestled in Preveza. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Keep the evening going at Roloi, a great choice for enjoying the after-dinner hours with a drink. You could also go to Markus Espresso & Wine Bar, which offers a similarly pleasant setting and great drinks. Another option is Metropolis Cafe (mitropolis Kafe), which provides an inviting environment for unwinding after a busy day out.

Raise your glass to another unforgettable day in Greece!

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Day3

Day 3

  • Preveza
  • Agios Nikitas
  • Fryni
  • Patras
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Drive 216 km, 3 hours 32 min

  • Kathisma 1
  • Faneromeni Monastery
  • Patras' South Park - Notio Parko Patras
  • Church of Agios Andreas
  • More

On day 3 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 3 destinations, including Agios Nikitas, Fryni, and Patras. When you’re not sightseeing, take time to relax at your chosen hotel in Patras, where you’ll be staying for 1 night.

Continue your road trip and head to your next destination, Agios Nikitas. This car ride takes around 58 min.

When you're ready for some sights, head to Kathisma 1, a locally renowned beach in Agios Nikitas. Explore its mesmerizing features at your own pace before you continue your journey.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Fryni may take around 18 min. Upon your arrival in Fryni, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Our first attraction recommendation in Fryni is Faneromeni Monastery, an intriguing monastery that draws attention for its historic features.

Continue your road trip and head to your next destination, Patras. This car ride takes around 1 hour 59 min.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Patras' South Park - Notio Parko Patras, an intriguing park that everyone visiting Patras should see. Next, head to Holy Church Of Saint Andrew. This majestic church is one of the most intriguing attractions in the region.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Patras. Patras offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Patras. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a delicious meal at Tag, a highly-rated dining destination in Patras. If you're eager to try something different, consider Bianco, another top spot with a tantalizing menu. You might also want to secure a reservation at Carousello. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Patras this evening.

Let the evening flow smoothly from dinner to drinks at Sofita, a top-rated bar in the area. For other recommendations, Charama Therino provides a perfect setting for rounding out your night with style and great drinks. Likewise, Notos offers a memorable night with diverse drink options and excellent service.

Relax and recharge in preparation for another adventurous day in Greece!

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Day4

Day 4

  • Patras
  • Antirio
  • Mesolongi
  • Ioannina
  • More

Drive 220 km, 2 hours 53 min

  • King George Ι Square (Patras)
  • St Nicholas Stairway
  • Patras Castle
  • Rion-Antirion Bridge
  • Garden of Heroes
  • More

Dive into day 4 of your remarkable road trip in Greece. Today you'll explore 3 destinations, including Patras, Antirio, and Mesolongi. At the end of the day, you’ll unwind at one of the finest accommodations in Ioannina, where you'll spend 1 night.

King George I Square (patras) makes a great addition to your morning plans. This often recommended public square is a visually striking place to see in Patras. Continue your discovery at St. Nicholas Stairway, an instagrammable street with stories to tell.

As you stroll around Patras, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Patras Castle. This increasingly popular castle offers a culturally significant encounter with Patras. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Patras.

When you’ve had your share of Patras, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Antirio. Your travel time is around 15 min.

Spend your afternoon discovering Charilaos Trikoupis Rio - Antirrio Bridge, an underrated monument known for its culturally significant features.

When you’re ready to jump back into the car and say goodbye to Antirio, you’ll hit the road in the direction of Mesolongi. This drive usually takes around 25 min.

Set out on a self-guided sightseeing tour at Garden Of Heroes and explore the picture-perfect features.

At the end of the day, you will drive to Ioannina, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ioannina, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Spitaki me thea, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Frontzoy Politeia - Frontzu Politia Restaurant is another top choice with a popular menu. You could also check for a table at Papi Cafe Bistro. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Ioannina tonight.

Cap off your dinner by heading to Scala, ideal for a leisurely evening with a drink in hand. Route 66 Bar is another bar that offers an enjoyable setting. Similarly, Palia Agora is also a popular place to go on a night out, perfect for relaxing and socializing.

As the sun sets, rest up and recharge for the next leg of your road trip in Greece.

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Day5

Day 5

  • Ioannina - Departure day
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  • The Clock Tower of Ioannina
  • More

Day 5 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Ioannina before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting The Clock Tower Of Ioannina, a respected monument before you head out.

Make the most of your final day in Greece by visiting Ioannina’s iconic markets and shopping establishments in the buzzing Epirus Street. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation. You can also browse through boutiques for stylish fashion choices. Savor your final moments in Greece at a cozy cafe while relaxing with a cup of coffee or tea.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Ioannina.

You’ll then say farewell to Ioannina. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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