5-Day Greece Self-Drive Road Trip With Itinerary from Kavala Prefecture to Thessaloniki and Kalambaka

1 / 48
Photo of aerial view the city of Kavala in northern Greek, ancient aqueduct Kamares, homes and beaches.
Perfect travel plans
Everything included
Fully customizable

Description

Included

Flights
Select dates
Hotel
Select dates
Car rental
Select dates
Tours & tickets
Select dates
Travel plan
From A to Z
Travel agent
24/7 fast service

Description

Explore the best of Greece on a 5-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Kavala Prefecture, Thessaloniki, Kastraki, Kalambaka, and Vergina. This road trip itinerary in Greece seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 2 nights in Kavala Prefecture, 1 night in Thessaloniki, and 1 night in Kalambaka. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Kavala Prefecture, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Meteora, learn more about the unique The Umbrellas Sculpture By Zogolopoulos, and immerse yourself in the vibrant atmosphere of Arch Of Galerius And Rotunda.

As you hit the open road and drive through Kavala Prefecture, Thessaloniki, Kastraki, Kalambaka, and Vergina, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

Read more

Travel details

Set your travel details to find the best price

Flights

Round trip
Round trip
Travel dates

Travelers

Rooms

Flights

Compare and choose from the best flights to Kavala Prefecture

Car

Choose from the best car rental deals or see all options

Driver’s age is 30 - 65
I live in

Personalize your itinerary

Customize tours under each day and destination

Day 1

Day 1

  • Kavala - Arrival day
  • More
  • Kavala Fort
  • More

Say hello to Kavala Prefecture! Your exciting road trip through Greece is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Kavala Prefecture for 1 night before you continue your adventure!

Kavala Prefecture is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Kavala Fortress, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Kavala Prefecture. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Kavala Prefecture, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Meltemi, an iconic dining spot in Kavala Prefecture. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Tsalapeteinos (Tsalapeteinos Urban Farm), a popular restaurant in Kavala Prefecture. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Marine Cafe Bar Restaurant, a hidden gem nestled in Kavala Prefecture. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Sofita, a well-loved spot among locals and tourists. Or, head to Beyond Cafe-bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Brickwall Pub, another top-rated place in the area.

Raise a toast to the start of your 5-day road trip in Greece!

Read more
Day 2

Day 2

  • Kavala
  • Thessaloniki
  • More

Drive 156 km, 2 hours 27 min

  • Kavala Archaeological Museum
  • Kapani
  • Agias Sofias Square
  • Aristotelous Square
  • More

Embark on another extraordinary experience on day 2 of your road trip in Greece. Today, you will make 2 stops and experience some of the highlights of Kavala Prefecture and Thessaloniki. At the end of the day, you will enjoy the comforts of a top-rated hotel in Thessaloniki, which will be your home away from home for 1 night.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Kavala Prefecture allows for both. Start by heading to Archaeological Museum Of Kavala. This intriguing museum provides an insightful glimpse into the city's identity. Next, discover Kapani, a visually striking market, promising a delightful encounter.

Continue your sightseeing with a visit to Agias Sofias Square, a captivating public square. When you’re done, don’t forget to make a stop at the popular Aristotelous Square.

When you’re done exploring for the day, you’ll drive to your hotel in Thessaloniki. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Thessaloniki. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Kitchen Bar, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, The Greek is another top choice with a popular menu. You could also check for a table at Phanós. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Thessaloniki tonight.

Extend your evening after a delightful meal by visiting Beetle Bar, which offers the perfect atmosphere for a night out. Moreover, Vogatsikou 3 is another popular option for a drink or two. Likewise, Souel also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Relax and recharge in preparation for another adventurous day in Greece!

Read more
Day 3

Day 3

  • Thessaloniki
  • Meteora
  • More

Drive 238 km, 3 hours 44 min

  • The Umbrellas by Zongolopoulos
  • Archaeological Museum of Thessaloniki
  • White Tower of Thessaloniki
  • Arch of Galerius
  • Meteora
  • More

Experience an unparalleled adventure on day 3 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Thessaloniki and Kastraki. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Kalambaka. You will spend 1 night here for some well-deserved relaxation.

Thessaloniki is home to plenty of attractions that offer family-friendly attractions, romantic experiences, and breathtaking views! Start at The Umbrellas Sculpture By Zogolopoulos, a notable art installation that is worthwhile a visit in the city. Nearby, you’ll find Archaeological Museum Of Thessaloniki, enchanting visitors with its standout appeal. Continue your exploration at White Tower Of Thessaloniki. This monument is one of the city’s most widely recognized spots.

Enjoy the freedom of exploring Thessaloniki at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Arch Of Galerius And Rotunda. After exploring the monument, head to the popular Meteora.

At the end of the day, you will drive to Kalambaka, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Kalambaka. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Get a good night's sleep and look forward to another great day on the road in Greece!

Read more
Day 4

Day 4

  • Meteora
  • Kavala
  • More

Drive 401 km, 5 hours 7 min

  • Monastery of the Holy Trinity at Meteora
  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Museum of the Royal Tombs at Aigai (Aegae)
  • More

On day 4 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 3 destinations, Kalambaka, Kastraki, and Vergina. When you’re not sightseeing, take time to relax at your selected hotel in Kavala Prefecture, where you’ll be staying for 1 night.

Prepare for a day full of fun adventures, scenic views, and photo-friendly spots. When you’re ready, kick off your sightseeing adventure at Monastery Of The Holy Trinity At Meteora. This up-and-coming monastery is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour, one of the town’s best highlights.

Next, check out Museum Of The Royal Tombs At Aigai (aegae), one of the most frequently visited places to see in Kalambaka. This museum is a favorite among locals and travelers alike.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Kavala Prefecture. Kavala Prefecture offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Kavala Prefecture's best restaurants.

Enjoy a delicious meal at FRANCO'S, a top-rated dining destination in Kavala Prefecture. If you're in the mood to try something new, consider Psaraki, another top spot with a mouthwatering menu. You might also want to secure a reservation at Proto Katsiki. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Kavala Prefecture this evening.

Explore the vibrant nightlife at Blue after your meal, a hub for lively evenings and memorable moments. Or, head to Meta Tis Deka for a great selection of flavorful drinks and a charming setting. Furthermore, Ypobrýchio is perfect for those looking to extend their night with a touch of local flavor.

Celebrate another amazing day of your road trip adventure in Greece!

Read more
Day 5

Day 5

  • Kavala - Departure day
  • More
  • Lighthouse of Kavala
  • More

Day 5 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Kavala Prefecture before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Lighthouse Of Kavala. This increasingly popular lighthouse is a popular place to see in the city.

On your last day in Greece, take time to indulge in shopping at Kavala Prefecture’s popular marketplace. Look for keepsakes or souvenirs to remind you of your trip.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Kavala Prefecture.

Treat yourself to a delicious dinner at “Paraliakon” Estiatorio, an excellent option for tonight's dining. Looking for something different? 180° sun & lounge offers a tantalizing alternative with its diverse menu. And don’t miss Krokodeilos.

You’ll then say farewell to Kavala Prefecture. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

Read more

How it works

Book your journey with Europe’s biggest travel platform—expert itineraries, instant confirmation, and full flexibility with 24/7 support.

Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

Similar travel packages

Discover other popular vacations in Greece

Link to appstore phone
Install Europe’s biggest travel app

Download Europe’s biggest travel marketplace to your phone to manage your entire trip in one place

Scan this QR code with your phone camera and press the link that appears to add Europe’s biggest travel marketplace into your pocket. Enter your phone number or email address to receive an SMS or email with the download link.