5-Day Greece Self-Drive Road Trip With Itinerary from Kavala Prefecture to Thessaloniki and Kalambaka

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Photo of Ammolofoi beach near Kavala, Greece, Europe. Nice sand and clear water.
Photo of aerial view the city of Kavala in northern Greek, ancient aqueduct Kamares, homes and beaches.
5-Day Greece Self-Drive Road Trip With Itinerary from Kavala Prefecture to Thessaloniki and Kalambaka
5-Day Greece Self-Drive Road Trip With Itinerary from Kavala Prefecture to Thessaloniki and Kalambaka
5-Day Greece Self-Drive Road Trip With Itinerary from Kavala Prefecture to Thessaloniki and Kalambaka
5-Day Greece Self-Drive Road Trip With Itinerary from Kavala Prefecture to Thessaloniki and Kalambaka
5-Day Greece Self-Drive Road Trip With Itinerary from Kavala Prefecture to Thessaloniki and Kalambaka
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Experience the freedom of the open road on an unforgettable 5-day road trip in Greece! Embark on a self-drive tour that caters to every traveler, featuring destinations like Kavala Prefecture, Thessaloniki, Kastraki, Kalambaka, and Vergina.

This perfectly planned road trip itinerary takes you through some of the best places to see in Greece. You will spend 2 nights in Kavala Prefecture, 1 night in Thessaloniki, and 1 night in Kalambaka. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Kavala Prefecture, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Kavala Prefecture, Thessaloniki, Kastraki, Kalambaka, and Vergina, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Day1

Day 1

  • Kavala - Arrival day
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  • Kavala Fort
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Welcome to Kavala Prefecture, the perfect starting point for your road trip in Greece! Pick up your rental car and let the adventure begin. You will spend 1 night discovering what to see in Kavala Prefecture before embarking on the next leg of your journey.

Kavala Prefecture is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Kavala Fortress. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Kavala Prefecture. Check-in typically starts around 2 to 4 PM at hotels in Greece. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Kavala Prefecture, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Meltemi, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Tsalapeteinos (Tsalapeteinos Urban Farm) is another top choice with a popular menu. You could also check for a table at Marine Cafe Bar Restaurant. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Kavala Prefecture tonight.

Round off your dining experience by visiting Sofita, a prime location for a drink. Alternatively, explore the distinctive characteristics of Beyond Cafe-bar, a bar catering to every mood and preference. Brickwall Pub likewise offers a unique atmosphere, perfect for a memorable night out.

Raise a toast to the start of your 5-day road trip in Greece!

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Day2

Day 2

  • Kavala
  • Thessaloniki
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Drive 156 km, 2 hours 27 min

  • Kavala Archaeological Museum
  • Kapani
  • Agias Sofias Square
  • Aristotelous Square
  • More

On day 2 of your road trip in Greece, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Kavala Prefecture and Thessaloniki are on today's agenda. In the evening, you’ll end up in Thessaloniki, where you will stay for 1 night.

One of the most often recommended attractions included on the itinerary is Archaeological Museum Of Kavala. This visually striking museum will help you start your sightseeing on top.

Throughout the day, make sure to take breaks to appreciate the surroundings.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Thessaloniki. This drive usually takes around 1 hour 48 min, without any stops or traffic disruptions.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Kapani, a well-known market that everyone visiting Thessaloniki should see. Next, head to Agias Sofias Square. This symbolic public square is one of the most locally renowned attractions in the region.

If you're keen to see more, don’t miss out on Aristotelous Square, an awe-inspiring public square popular among locals as well as travelers.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Thessaloniki. Thessaloniki offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Thessaloniki's most popular restaurants, and connect with friendly locals for a true cultural experience.

Make sure to reserve a table at Kitchen Bar, an iconic dining spot in Thessaloniki. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of The Greek, a popular restaurant in Thessaloniki. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Phanós, a hidden gem nestled in Thessaloniki. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

To truly maximize your evening out, consider visiting Beetle Bar after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Vogatsikou 3, another bar with an inviting ambiance. Similarly, Souel also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

As the sun sets, rest up and recharge for the next leg of your road trip in Greece.

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Day3

Day 3

  • Thessaloniki
  • Kastraki
  • Meteora
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Drive 238 km, 3 hours 44 min

  • The Umbrellas by Zongolopoulos
  • Archaeological Museum of Thessaloniki
  • White Tower of Thessaloniki
  • Arch of Galerius
  • Meteora
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Experience an unparalleled adventure on day 3 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Thessaloniki and Kastraki. At the end of the day, you will retreat to the hotel of your choice in Kalambaka, where will spend 1 night.

Make a stop at The Umbrellas Sculpture By Zogolopoulos. This notable art installation is a must-visit for travelers looking for a unique holiday experience. Make your way to Archaeological Museum Of Thessaloniki located in Thessaloniki for another exciting encounter.

Next, immerse yourself in the setting of White Tower Of Thessaloniki. Its picture-perfect features will captivate you. After the monument, continue your tour of the city with a visit to Arch Of Galerius And Rotunda. Visitors usually appreciate the symbolic features of this monument.

After soaking in Thessaloniki’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Kastraki. Expect your car journey to take a minimum of 2 hours 53 min. When you arrive in Kastraki, it's time to take a break from the road.

When you're ready for some sights, head to Meteora, a well-known monastery in Kastraki. Explore its picturesque features at your own pace before you continue your journey.

When you’re done exploring for the day, you’ll drive to your hotel in Kalambaka. Check in and relax before you head out to tour the town.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Kalambaka. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Say good night to Kalambaka and look forward to another great day of your road trip in Greece!

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Day4

Day 4

  • Meteora
  • Kastraki
  • Vergina
  • Kavala
  • More

Drive 401 km, 5 hours 7 min

  • Monastery of the Holy Trinity at Meteora
  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Museum of the Royal Tombs at Aigai (Aegae)
  • More

Dive into day 4 of your remarkable road trip in Greece. Today you'll explore 3 destinations, including Kalambaka, Kastraki, and Vergina. At the end of the day, you’ll unwind at one of the finest accommodations in Kavala Prefecture, where you'll spend 1 night.

Whatever your travel style is, Monastery Of The Holy Trinity At Meteora is an essential stop in Kalambaka. This curiosity-inducing monastery provides an insightful glimpse into the town's identity.

Embrace the thrill of the open road as you wave goodbye to Kalambaka and set your GPS to Kastraki. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 7 min. Upon reaching Kastraki, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Our first attraction recommendation in Kastraki is Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour, a locally appreciated monastery that draws attention for its breathtaking features.

Embrace the thrill of the open road as you wave goodbye to Kastraki and set your GPS to Vergina. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 2 hours 17 min. Upon reaching Vergina, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

One of our top recommendations for your sightseeing is Museum Of The Royal Tombs At Aigai (aegae). Spend some time admiring the heritage-rich features of the museum before you continue to your next stop.

At the end of the day, you will drive to Kavala Prefecture, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Kavala Prefecture. Enjoy a relaxing evening as you savor delicious local cuisine.

Don’t miss out on dining at FRANCO'S, a top-rated dining destination in Kavala Prefecture. If you're in the mood to try something new, consider Psaraki, another top spot with a mouthwatering menu. You might also want to secure a reservation at Proto Katsiki. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Kavala Prefecture this evening.

Continue the enjoyment post-dinner at Blue, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Meta Tis Deka offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Ypobrýchio. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Raise your glass and celebrate another amazing day of your road trip in Greece!

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Day5

Day 5

  • Kavala - Departure day
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  • Lighthouse of Kavala
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Day 5 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Kavala Prefecture before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Lighthouse Of Kavala, an instagrammable lighthouse before you head out.

Make the most of your final day in Greece by visiting Kavala Prefecture’s iconic markets and shopping establishments. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Kavala Prefecture.

If you're eager to try something different, consider 180° sun & lounge, another top spot with a tantalizing menu.

You’ll then say farewell to Kavala Prefecture. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
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Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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