5-Day Greece Self-Drive Road Trip With Itinerary from Patras to Kalambaka and Thessaloniki

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Back view of cute boy looking at the Patras lighthouse, Peloponnese, Greece. The lighthouse located on the seafront near Saint Andrew's Cathedral, is the symbol of Patras Town.
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Escape the ordinary with this exciting 5-day road trip through Greece. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Greece. You will spend 2 nights in Patras, 1 night in Kalambaka, and 1 night in Thessaloniki. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Patras, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Arch Of Galerius And Rotunda, learn more about the unique Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour, and immerse yourself in the vibrant atmosphere of Temple Of Apollo In Delphi.

As you hit the open road and drive through Patras, Delphi, Kalambaka, Kastraki, Thessaloniki, and Nafpaktos, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
Drop-off: 10:00

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Day 1

Day 1

  • Patras - Arrival day
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  • Church of Agios Andreas
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Your road trip adventure in Greece begins as soon as you reach Patras and pick up your car. You’ll stay here for 1 night and explore what to see in Patras, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Patras is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Holy Church Of Saint Andrew, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Patras. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Patras, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Tag, an iconic dining spot in Patras. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bianco, a popular restaurant in Patras. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Carousello, a hidden gem nestled in Patras. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue your evening by exploring the vibrant nightlife scene at Sofita, a prime destination for a thrilling night out. Also, don’t forget to check out Charama Therino, a bar that offers unique local touches. Likewise, Notos provides an excellent alternative for a fun evening.

Raise a toast to the start of your 5-day road trip in Greece!

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Day 2

Day 2

  • Patras
  • Meteora
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Drive 353 km, 5 hours 1 min

  • Temple of Apollo
  • Monastery of the Holy Trinity at Meteora
  • Main Observation Deck of Meteora
  • Greek Education Museum
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Dive into day 2 of your remarkable road trip in Greece. Today you'll explore 3 destinations, including Delphi, Kalambaka, and Kastraki. At the end of the day, you’ll unwind at one of the finest accommodations in Kalambaka, where you'll spend 1 night.

Enjoy all that Temple Of Apollo In Delphi has to offer. This is a frequently visited archeological site you should not miss. Another must-see is Monastery Of The Holy Trinity At Meteora, an increasingly popular monastery in Patras.

When you’re ready for the next sight, head to Main Observation Deck Of Meteora. From there, take a leisurely stroll to Greek Education Museum, another of the village’s frequently visited attractions.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Kalambaka. Kalambaka offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Kalambaka. Enjoy a relaxing evening as you savor delicious local cuisine.

Head back to your accommodation in Kalambaka and get some rest to prepare for another magical day of your road trip in Greece.

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Day 3

Day 3

  • Meteora
  • Thessaloniki
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Drive 239 km, 3 hours 51 min

  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Monastery of Varlaam
  • Arch of Galerius
  • Aristotelous Square
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On day 3 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 2 destinations, including Kastraki and Thessaloniki. When you’re not sightseeing, take time to relax at your chosen hotel in Thessaloniki, where you’ll be staying for 1 night.

Whatever your travel style is, Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour is an essential stop in Kalambaka. This underrated monastery provides an insightful glimpse into the village's identity. Next, discover Monastery Of Varlaam, a stunning monastery, promising a delightful encounter.

Continue your sightseeing with a visit to Arch Of Galerius And Rotunda, a notable monument. When you’re done, don’t forget to make a stop at the notable Aristotelous Square.

At the end of the day, you will drive to Thessaloniki, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Thessaloniki's best restaurants.

Enjoy a delicious meal at Kitchen Bar, a highly-rated dining destination in Thessaloniki. If you're eager to try something different, consider The Greek, another top spot with a tantalizing menu. You might also want to secure a reservation at Phanós. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Thessaloniki this evening.

Continue the enjoyment post-dinner at Beetle Bar, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Vogatsikou 3 offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Souel. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Get a good night's sleep and look forward to another great day on the road in Greece!

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Day 4

Day 4

  • Thessaloniki
  • Patras
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Drive 491 km, 5 hours 42 min

  • White Tower of Thessaloniki
  • Archaeological Museum of Thessaloniki
  • Museum of Byzantine Civilization
  • Άγαλμα Μιγκέλ Θερβάντες
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On day 4 of your road trip in Greece, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Thessaloniki and Nafpaktos are on today's agenda. In the evening, you’ll end up in Patras, where you will stay for 1 night.

Visiting White Tower Of Thessaloniki is always a good idea. This top-rated monument is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the historic wonders of Archaeological Museum Of Thessaloniki, a must-see museum in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Museum Of Byzantine Culture. This intriguing museum offers an enriching experience. For a change of pace, head to Miguel De Cervantes Monument, where you can take in breathtaking features. These sights offer a fulfilling end to a perfect day.

When you’re done exploring for the day, you’ll drive to your hotel in Patras. Check in and relax before you head out to tour the city.

Patras is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Patras.

Make sure to reserve a table at Fork, an iconic dining spot in Patras. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Flouskounis food, a popular restaurant in Patras. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Big Ben, a hidden gem nestled in Patras. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Let the evening flow smoothly from dinner to drinks at Minimal, a top-rated bar in the area. For other recommendations, Beer Bar Q provides a perfect setting for rounding out your night with style and great drinks. Likewise, Distinto Mall offers a memorable night with diverse drink options and excellent service.

Say good night to Patras and look forward to another great day of your road trip in Greece!

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Day 5

Day 5

  • Patras - Departure day
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  • Patras' South Park - Notio Parko Patras
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Day 5 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Patras before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Patras' South Park - Notio Parko Patras, a picturesque park before you head out.

Make the most of your final day in Greece by visiting Patras’s iconic markets and shopping establishments. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Patras.

You’ll then say farewell to Patras. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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