5-Day Greece Self-Drive Road Trip With Itinerary from Patras to Kalambaka and Thessaloniki

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Back view of cute boy looking at the Patras lighthouse, Peloponnese, Greece. The lighthouse located on the seafront near Saint Andrew's Cathedral, is the symbol of Patras Town.
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Explore the best of Greece on a 5-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Patras, Delphi, Kalambaka, Kastraki, Thessaloniki, and Nafpaktos. This road trip itinerary in Greece seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 2 nights in Patras, 1 night in Kalambaka, and 1 night in Thessaloniki. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Patras, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Arch Of Galerius And Rotunda, learn more about the unique Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour, and immerse yourself in the vibrant atmosphere of Temple Of Apollo In Delphi.

As you hit the open road and drive through Patras, Delphi, Kalambaka, Kastraki, Thessaloniki, and Nafpaktos, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Church of Agios Andreas
Temple of ApolloMonastery of the Holy Trinity at MeteoraMain Observation Deck of MeteoraGreek Education Museum
The Great Meteoron Holy Monastery of the Transfiguration of the SaviourMonastery of VarlaamArch of GaleriusAristotelous Square
White Tower of ThessalonikiArchaeological Museum of ThessalonikiMuseum of Byzantine CivilizationΆγαλμα Μιγκέλ Θερβάντες
Patras' South Park - Notio Parko Patras

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Day 1

Day 1

  • Patras - Arrival day
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  • Church of Agios Andreas
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Welcome to Patras, the perfect starting point for your road trip in Greece! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Patras's charm before embarking on the next leg of your journey.

Patras is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Holy Church Of Saint Andrew, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Patras. Check-in typically starts around 2 to 4 PM at hotels in Greece. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Patras, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at Tag, an excellent option for tonight's dining. Looking for something different? Bianco offers a tantalizing alternative with its diverse menu. And don’t miss Carousello. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Patras.

Explore the vibrant nightlife at Sofita after your meal, a hub for lively evenings and memorable moments. Or, head to Charama Therino for a great selection of flavorful drinks and a charming setting. Furthermore, Notos is perfect for those looking to extend their night with a touch of local flavor.

Raise a toast to the start of your 5-day road trip in Greece!

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Day 2

Day 2

  • Patras
  • Meteora
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Drive 353 km, 5 hours 1 min

  • Temple of Apollo
  • Monastery of the Holy Trinity at Meteora
  • Main Observation Deck of Meteora
  • Greek Education Museum
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On day 2 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 3 destinations, Delphi, Kalambaka, and Kastraki. When you’re not sightseeing, take time to relax at your selected hotel in Kalambaka, where you’ll be staying for 1 night.

Patras is brimming with adventures. Today’s wonderful stops include an archeological site, a monastery, an observation deck, a museum and much more! Begin your sightseeing adventure at the often recommended Temple Of Apollo In Delphi and allow yourself time to explore. Just a short distance away you'll find your next stop, Monastery Of The Holy Trinity At Meteora, a picture-perfect monastery that draws visitors from far and near.

Continue your journey to Main Observation Deck Of Meteora, one of the village’s most intriguing spots that you shouldn’t miss. Another great site to visit is the increasingly popular Greek Education Museum.

When you’re done exploring for the day, you’ll drive to your hotel in Kalambaka. Check in and spend some time relaxing before you head out to tour the town.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Kalambaka. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Raise your glass to another unforgettable day in Greece!

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Day 3

Day 3

  • Meteora
  • Thessaloniki
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Drive 239 km, 3 hours 51 min

  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Monastery of Varlaam
  • Arch of Galerius
  • Aristotelous Square
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Embark on another extraordinary experience on day 3 of your road trip in Greece. Today, you will make 2 stops and experience some of the highlights of Kastraki and Thessaloniki. At the end of the day, you will enjoy the comforts of a top-rated hotel in Thessaloniki, which will be your home away from home for 1 night.

Bring your curiosity for today’s adventure around Kalambaka. Some of the village’s most loved attractions await! Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour is the perfect place to start. This monastery is one of the most frequently visited places to visit in Kalambaka. Next, head to Monastery Of Varlaam, a locally appreciated monastery, known for its breathtaking features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Arch Of Galerius And Rotunda. This symbolic monument is a highly recommended experience. Nearby, you'll also find Aristotelous Square. Visit these for an interesting touch to your journey.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Thessaloniki. Thessaloniki offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Thessaloniki's best restaurants.

Make sure to reserve a table at Kitchen Bar, an iconic dining spot in Thessaloniki. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of The Greek, a popular restaurant in Thessaloniki. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Phanós, a hidden gem nestled in Thessaloniki. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

To truly maximize your evening out, consider visiting Beetle Bar after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Vogatsikou 3, another bar with an inviting ambiance. Similarly, Souel also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Head back to your accommodation in Thessaloniki and get some rest in preparation for another magical day of your road trip in Greece!

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Day 4

Day 4

  • Thessaloniki
  • Patras
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Drive 491 km, 5 hours 42 min

  • White Tower of Thessaloniki
  • Archaeological Museum of Thessaloniki
  • Museum of Byzantine Civilization
  • Άγαλμα Μιγκέλ Θερβάντες
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On day 4 of your road trip in Greece, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Thessaloniki and Nafpaktos. In the evening, you’ll end up in Patras, where you will stay for 1 night.

Set out on a day brimming with family-friendly attractions, breathtaking views, and photo-friendly spots. Start at the top-rated White Tower Of Thessaloniki, a culturally significant monument in Thessaloniki. Next, go to Archaeological Museum Of Thessaloniki.

After visiting White Tower Of Thessaloniki and Archaeological Museum Of Thessaloniki, have a stroll along Thessaloniki's streets and take in the local charm. Continue your sightseeing by heading to Museum Of Byzantine Culture. This instagrammable museum offers a unique experience. Miguel De Cervantes Monument is another noteworthy attraction worthwhile a visit.

At the end of the day, you will drive to Patras, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Patras. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a fantastic dining experience at Fork, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Flouskounis food offers an enticing alternative with its varied menu. Additionally, Big Ben is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Patras.

Continue your evening by exploring the vibrant nightlife scene at Minimal, a prime destination for a thrilling night out. Also, don’t forget to check out Beer Bar Q, a bar that offers unique local touches. Likewise, Distinto Mall provides an excellent alternative for a fun evening.

Take some time to reflect on your day and savor another beautiful night in Greece.

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Day 5

Day 5

  • Patras - Departure day
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  • Patras' South Park - Notio Parko Patras
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Day 5 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Patras before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Patras' South Park - Notio Parko Patras. This increasingly popular park is a popular place to see in the city.

Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Patras.

Have a fantastic dining experience at Labyrinthos, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Marogia offers an enticing alternative with its varied menu.

You’ll then say farewell to Patras. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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