5-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki to Kalambaka

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Photo of bird's eye view to the promenade of Thessaloniki.
Photo of Saint Paul cathedral in Thessaloniki, Greece.
5-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki to Kalambaka
5-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki to Kalambaka
5-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki to Kalambaka
5-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki to Kalambaka
5-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki to Kalambaka
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Escape the ordinary with this exciting 5-day road trip through Greece. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Greece. You will spend 3 nights in Thessaloniki and 1 night in Kalambaka. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Thessaloniki, Kastraki, Kalambaka, Dion, and Neos Panteleimonas, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day1

Day 1

  • Thessaloniki - Arrival day
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  • Ladadika
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Welcome to Thessaloniki, the perfect starting point for your road trip in Greece! Pick up your rental car and let the adventure begin. You will spend 2 nights discovering what to see in Thessaloniki before embarking on the next leg of your journey.

Thessaloniki is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Thessaloniki. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Greece. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Kitchen Bar, a highly recommended choice for tonight's dinner. If you're looking to mix things up, The Greek offers an enticing alternative with its varied menu. Additionally, Phanós is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Thessaloniki.

Extend your evening after a delightful meal by visiting Beetle Bar, which offers the perfect atmosphere for a night out. Moreover, Vogatsikou 3 is another popular option for a drink or two. Likewise, Souel also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Raise a toast to the start of your 5-day road trip in Greece!

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Day2

Day 2

  • Thessaloniki
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Drive 6 km, 55 min

  • Aristotelous Square
  • Agias Sofias Square
  • Arch of Galerius
  • White Tower of Thessaloniki
  • Archaeological Museum of Thessaloniki
  • Tsimiski Street
  • More

On day 2 of your road trip, you will have an entire day to discover what to see in Thessaloniki. You’ll stay in Thessaloniki for 1 night.

A top thing to do today is to explore Tsimiski Street, a must-see street in Thessaloniki. It's the perfect starting point for touring the top attractions in the area.

Catch Aristotelous Square before the crowds roll in. This history-steeped public square is sure to ignite your curiosity. Next, dive into the symbolic features of Agias Sofias Square, a must-visit public square in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Arch Of Galerius And Rotunda, a popular monument. For a change of scene, check out White Tower Of Thessaloniki, known for its awe-inspiring features. We also recommend visiting Archaeological Museum Of Thessaloniki. This museum is a must for anyone looking to experience the city to the fullest.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Greece. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Thessaloniki. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a wonderful meal at Mamalouka, a top-rated dining spot in Thessaloniki. If you're in the mood for something new, try Clochard, another premier location with a delectable menu. You might also want to book a table at Sofi's House Restaurant. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Thessaloniki.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Castra- All Day Terrace Bar, known for its inviting atmosphere. Barbaben - Bar/ba/ben is another great option if you’re looking for a place to get the night started. Similarly, Apallou provides a great setting to enjoy the night away.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Greece.

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Day3

Day 3

  • Thessaloniki
  • Kastraki
  • Meteora
  • More

Drive 240 km, 3 hours 33 min

  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Monastery of Varlaam
  • Main Observation Deck of Meteora
  • Natural History Museum of Meteora and Mushroom Museum
  • Greek Education Museum
  • More

On day 3 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 2 destinations, including Kastraki and Kalambaka. When you’re not sightseeing, take time to relax at your chosen hotel in Kalambaka, where you’ll be staying for 1 night.

Set your GPS to Kastraki and hit the road. Expect a journey of approximately 2 hours 53 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Kastraki beckons with new experiences!

Our first attraction recommendation in Kastraki is Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour, an often recommended monastery that draws attention for its historic features. Spend some time soaking in the atmosphere before continuing to Monastery Of Varlaam, an UNESCO world heritage-designated monastery that stands out in the village.

Time flies when you're having fun! But don't forget to stop for a bit to eat and drink between your adventures. When you're rested and recharged, head to Main Observation Deck Of Meteora, an increasingly popular observation deck that offers a unique experience.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Kalambaka. This drive usually takes around 11 min, without any stops or traffic disruptions.

When you're ready for some sights, head to Natural History Museum Of Meteora And Mushroom Museum, a worthwhile museum in Kalambaka. Explore its instagrammable features at your own pace before you continue your journey to your next attraction, Greek Education Museum. This locally appreciated museum is a top recommendation in the area.

At the end of the day, you will drive to Kalambaka, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Kalambaka is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Kalambaka.

Celebrate another amazing day of your road trip adventure in Greece!

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Day4

Day 4

  • Meteora
  • Dion
  • Neos Panteleimonas
  • Thessaloniki
  • More

Drive 321 km, 4 hours 32 min

  • Archaeological Site of Dion
  • Καταρράκτες Ενιπεα (Μονής Αγίου Διονυσίου)
  • Byzantine Castle of Platamon
  • More

Your itinerary for day 4 of your road trip in Greece includes 3 stops and features some of the highlights of Dion, Litochoro, and Neos Panteleimonas. At the end of the day, enjoy the comforts of a top-rated hotel in Thessaloniki, where you'll spend 1 night.

Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Dion.

Fasten your seatbelt and make your way to your next stop — Dion, home to many well-known sights in the region. Keep in mind that your travel time from Kalambaka to Dion may take around 1 hour 55 min without traffic disruptions. Upon arrival in Dion, we highly recommend checking out some of the top attractions.

Savor the day by heading to Archaeological Park Of Dion, a curiosity-inducing archeological site that draws visitors from near and far.

Continue your road trip and head to your next destination, Litochoro. This car ride takes around 37 min.

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Enipeas Falls, a worthwhile waterfall that everyone visiting Litochoro should see.

When you’re ready to jump back into the car and say goodbye to Litochoro, you’ll hit the road in the direction of Neos Panteleimonas. This drive usually takes around 47 min.

For a more meaningful self-guided tour of the village's best attractions, visit Platamon Castle, an underrated castle that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

When you’re done exploring for the day, you’ll drive to your hotel in Thessaloniki. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Thessaloniki. Enjoy a relaxing evening as you savor delicious local cuisine.

Have a fantastic dining experience at Enoches Bar, a highly recommended choice for tonight's dinner. If you're looking to mix things up, O Loytros offers an enticing alternative with its varied menu. Additionally, rOOTS is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Thessaloniki.

Unwind after your meal by stepping into Peiratis Cafe-bar. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, In Rock Cafe Bar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Tribeca, another top-rated bar in the area.

Raise your glass and celebrate another amazing day of your road trip in Greece!

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Day5

Day 5

  • Thessaloniki - Departure day
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  • The Umbrellas by Zongolopoulos
  • More

Day 5 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting The Umbrellas Sculpture By Zogolopoulos, a noteworthy art installation before you head out.

For a last-minute shopping spree in Thessaloniki, Modiano Market is nearby. Enjoy a variety of retail stores, dining options, and essential services in one convenient location.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

Dine in style at Millet, a top recommendation for dinner tonight. Or, for a change of pace, Agora Ouzeri boasts a menu that's sure to impress.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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