5-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling east to Kavala Prefecture

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Experience the freedom of the open road in Greece as you embark on an unforgettable 5-day road trip! This experience caters to every traveler, featuring destinations like Thessaloniki, Kavala Prefecture, Lydia, and Krinides.

This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 3 nights in Thessaloniki and 1 night in Kavala Prefecture. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable The Umbrellas Sculpture By Zogolopoulos, learn more about the unique Arch Of Galerius And Rotunda, and immerse yourself in the vibrant atmosphere of Kapani.

As you hit the open road and drive through Thessaloniki, Kavala Prefecture, Lydia, and Krinides, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Ladadika
Aristotelous SquareAgias Sofias SquareWhite Tower of ThessalonikiArchaeological Museum of ThessalonikiTsimiski Street
KapaniChurch of St DemetriosArch of GaleriusAtatürk MuseumHeptapyrgion of Thessalonica
Kavala FortHoly Baptistery of Saint Lydia of PhilippiArchaeological Museum of PhilippiAncient theatre of Philippi
The Umbrellas by Zongolopoulos

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Day 1

Day 1

  • Thessaloniki - Arrival day
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  • Ladadika
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Your road trip adventure in Greece begins as soon as you reach Thessaloniki and pick up your car. You’ll stay in Thessaloniki for 2 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Thessaloniki is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ladadika, a must-see neighborhood, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Thessaloniki. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Greece. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Kitchen Bar, an iconic dining spot in Thessaloniki. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of The Greek, a popular restaurant in Thessaloniki. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Phanós, a hidden gem nestled in Thessaloniki. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Unwind after your meal by stepping into Beetle Bar. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Vogatsikou 3 offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Souel, another top-rated bar in the area.

Raise a toast to the start of your 5-day road trip in Greece!

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Day 2

Day 2

  • Thessaloniki
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Drive 5 km, 49 min

  • Aristotelous Square
  • Agias Sofias Square
  • White Tower of Thessaloniki
  • Archaeological Museum of Thessaloniki
  • Tsimiski Street
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On day 2 of your road trip, you will have an entire day to explore Thessaloniki. You’ll stay in Thessaloniki for 1 night and discover all the best things to see and do in the area.

Tsimiski Street is one of the highlights of today. Take your time exploring this iconic street in Thessaloniki, which offers a perfect blend of history and culture. Plus, it's close to many must-see landmarks in the city.

Today's adventure in Thessaloniki promises more breathtaking discoveries and enriching experiences! Begin at Aristotelous Square. This enchanting public square is a highlight of any visit in the city. Then, enjoy Agias Sofias Square, another photogenic attraction that never fails to captivate visitors. Next, head over to White Tower Of Thessaloniki, one of the city’s most widely recognized attractions, known for its picture-perfect features.

If you’re looking for more, spend time soaking in the atmosphere of Archaeological Museum Of Thessaloniki. This respected museum is frequented by locals and tourists alike. To complete your memorable day, make sure to take a stroll around the area.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Greece is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Thessaloniki. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delicious dinner at Mamalouka, an excellent option for tonight's dining. Looking for something different? Clochard offers a tantalizing alternative with its diverse menu. And don’t miss Sofi's House Restaurant. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Thessaloniki.

After enjoying a fulfilling meal, continue your evening at Castra- All Day Terrace Bar, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Barbaben - Bar/ba/ben offers a welcoming atmosphere for easing into the nightlife. Similarly, Apallou provides an excellent environment for a relaxed and enjoyable evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Greece.

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Day 3

Day 3

  • Thessaloniki
  • Kavala
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Drive 158 km, 2 hours 48 min

  • Kapani
  • Church of St Demetrios
  • Arch of Galerius
  • Atatürk Museum
  • Heptapyrgion of Thessalonica
  • More

Dive into day 3 of your remarkable road trip in Greece. Today you will explore Thessaloniki, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Kavala Prefecture. You’ll stay here for 1 night.

Start by visiting Kapani, a prime spot to begin your journey. This heritage-rich market is sure to impress. Next on your list is Holy Church Of Saint Demetrius, Patron Saint Of Thessalonica, another must-visit landmark and beloved church renowned for its photogenic features.

While exploring and sightseeing, take time to savor the culture of Thessaloniki by sampling some local delicacies. When you’re ready for more sightseeing, head to Arch Of Galerius And Rotunda. This eye-catching monument is an essential place to visit for anyone looking for the full Thessaloniki experience. We also recommend visiting Atatürk Museum, a frequently visited museum. Nearby, you'll also find Heptapyrgion Of Thessaloniki, ready to add charm to your journey.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Kavala Prefecture. Kavala Prefecture offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Kavala Prefecture. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Meltemi, a highly-rated dining destination in Kavala Prefecture. If you're eager to try something different, consider Tsalapeteinos (Tsalapeteinos Urban Farm), another top spot with a tantalizing menu. You might also want to secure a reservation at Marine Cafe Bar Restaurant. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Kavala Prefecture this evening.

Extend your evening after a delightful meal by visiting Sofita, which offers the perfect atmosphere for a night out. Moreover, Beyond Cafe-bar is another popular option for a drink or two. Likewise, Brickwall Pub also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Raise your glass and celebrate another amazing day of your road trip in Greece!

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Day 4

Day 4

  • Kavala
  • Thessaloniki
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Drive 181 km, 2 hours 51 min

  • Kavala Fort
  • Holy Baptistery of Saint Lydia of Philippi
  • Archaeological Museum of Philippi
  • Ancient theatre of Philippi
  • More

On day 4 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 3 destinations, Kavala Prefecture, Lydia, and Krinides. When you’re not sightseeing, take time to relax at your selected hotel in Thessaloniki, where you’ll be staying for 1 night.

A blend of fun adventures, romantic experiences, and breathtaking views await you in Kavala Prefecture on today’s itinerary. First up is the beloved castle, Kavala Fortress. Afterward, continue to Holy Baptistery Of Saint Lydia Of Philippi, a church every traveler should visit.

As you explore Kavala Prefecture’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Archaeological Museum Of Philippi. This up-and-coming museum is an essential stop. Following that, head to Ancient Theatre Of Philippi, another must-visit site that will enhance your experience.

When you’re done exploring for the day, you’ll drive to your hotel in Thessaloniki. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Thessaloniki's best restaurants.

Enjoy a delicious meal at Enoches Bar, a top-rated dining destination in Thessaloniki. If you're in the mood to try something new, consider O Loytros, another top spot with a mouthwatering menu. You might also want to secure a reservation at rOOTS. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Thessaloniki this evening.

Unwind after your meal by stepping into Peiratis Cafe-bar. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, In Rock Cafe Bar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Tribeca, another top-rated bar in the area.

Take some time to reflect on your day and savor another beautiful night in Greece.

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Day 5

Day 5

  • Thessaloniki - Departure day
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  • The Umbrellas by Zongolopoulos
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Day 5 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting The Umbrellas Sculpture By Zogolopoulos, a noteworthy art installation before you head out.

As your final day in Greece unfolds, enjoy a last-minute shopping spree in Thessaloniki's best shopping area, Tsimiski Street. Enjoy finding the perfect gift or keepsake to remind you of your wonderful trip to Greece. Browse through boutiques to find unique and stylish fashion pieces to take home.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

Dine in style at Millet, a top recommendation for dinner tonight. Or, for a change of pace, Agora Ouzeri boasts a menu that's sure to impress.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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