5-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling east to Kavala Prefecture

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Photo of Saint Paul cathedral in Thessaloniki, Greece.
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Explore the best of Greece on a remarkable 5-day road trip! Combine exploration with relaxation on a self-drive tour featuring Thessaloniki, Kavala Prefecture, Lydia, and Krinides.

This perfectly planned road trip itinerary takes you through some of the best places to see in Greece. You will spend 3 nights in Thessaloniki and 1 night in Kavala Prefecture. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Thessaloniki, Kavala Prefecture, Lydia, and Krinides, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day1

Day 1

  • Thessaloniki - Arrival day
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  • Ladadika
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Your road trip adventure in Greece begins as soon as you reach Thessaloniki and pick up your car. You’ll stay here for 2 nights and explore what to see in Thessaloniki, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Thessaloniki is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Thessaloniki. Check-in typically starts around 2 to 4 PM at hotels in Greece. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Kitchen Bar, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, The Greek is another top choice with a popular menu. You could also check for a table at Phanós. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Thessaloniki tonight.

Let the evening flow smoothly from dinner to drinks at Beetle Bar, a top-rated bar in the area. For other recommendations, Vogatsikou 3 provides a perfect setting for rounding out your night with style and great drinks. Likewise, Souel offers a memorable night with diverse drink options and excellent service.

Raise a toast to the start of your 5-day road trip in Greece!

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Day2

Day 2

  • Thessaloniki
  • More

Drive 5 km, 49 min

  • Aristotelous Square
  • Agias Sofias Square
  • White Tower of Thessaloniki
  • Archaeological Museum of Thessaloniki
  • Tsimiski Street
  • More

On day 2 of your road trip, you will have an entire day to discover what to see in Thessaloniki. You’ll stay in Thessaloniki for 1 night.

Don’t miss Tsimiski Street today, a must-see street that offers a glimpse into the city’s vibrant character. Take your time to explore its best features, and enjoy the convenience of nearby top-rated landmarks.

Whatever your travel style is, Aristotelous Square is an essential stop in Thessaloniki. This captivating public square provides an insightful glimpse into the city's identity. Next, discover Agias Sofias Square, a heritage-rich public square, promising a delightful encounter.

Continue your sightseeing with a visit to White Tower Of Thessaloniki, an astonishing monument. When you’re done, don’t forget to make a stop at the up-and-coming Archaeological Museum Of Thessaloniki.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Greece. You can explore and select activities under each day of your itinerary.

For an unforgettable shopping experience, visit Modiano Market, the top shopping destination in Thessaloniki. Browse local shops and stores, each offering delightful surprises. Find unique souvenirs or items to take home. After shopping, explore what Modiano Market has to offer, including attractions, essential services, and vibrant community activities.

Thessaloniki is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Thessaloniki.

Don’t miss out on dining at Mamalouka, a top-rated dining destination in Thessaloniki. If you're in the mood to try something new, consider Clochard, another top spot with a mouthwatering menu. You might also want to secure a reservation at Sofi's House Restaurant. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Thessaloniki this evening.

To truly maximize your evening out, consider visiting Castra- All Day Terrace Bar after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Barbaben - Bar/ba/ben, another bar with an inviting ambiance. Similarly, Apallou also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Relax and look forward to more memorable moments to come!

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Day3

Day 3

  • Thessaloniki
  • Kavala
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Drive 158 km, 2 hours 48 min

  • Kapani
  • Church of St Demetrios
  • Arch of Galerius
  • Atatürk Museum
  • Heptapyrgion of Thessalonica
  • More

On day 3 of your road trip in Greece, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Thessaloniki are on today's agenda. In the evening, you’ll end up in Kavala Prefecture, where you will stay for 1 night.

Awaiting your discovery is the captivating Kapani, an instagrammable market in Thessaloniki. Next, go to Holy Church Of Saint Demetrius, Patron Saint Of Thessalonica.

After visiting Kapani and Holy Church Of Saint Demetrius, Patron Saint Of Thessalonica, have a stroll along Thessaloniki's streets and take in the local charm. Continue your sightseeing by heading to Arch Of Galerius And Rotunda. This photogenic monument offers a unique experience. Atatürk Museum is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Heptapyrgion Of Thessaloniki, one of the most breathtaking places to visit in Thessaloniki.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Kavala Prefecture. Kavala Prefecture offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Kavala Prefecture. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Savor the flavors at Meltemi, a top pick for dinner tonight. Alternatively, Tsalapeteinos (Tsalapeteinos Urban Farm) beckons with its unique menu offerings. Also, consider Marine Cafe Bar Restaurant. With its consistent customer satisfaction, it’s an excellent option for dining in Kavala Prefecture tonight.

After enjoying a fulfilling meal, continue your evening at Sofita, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Beyond Cafe-bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Brickwall Pub provides an excellent environment for a relaxed and enjoyable evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Greece.

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Day4

Day 4

  • Kavala
  • Thessaloniki
  • More

Drive 181 km, 2 hours 51 min

  • Kavala Fort
  • Holy Baptistery of Saint Lydia of Philippi
  • Archaeological Museum of Philippi
  • Ancient theatre of Philippi
  • More

On day 4 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 3 destinations, including Kavala Prefecture, Lydia, and Krinides. When you’re not sightseeing, take time to relax at your chosen hotel in Thessaloniki, where you’ll be staying for 1 night.

Make a stop at Kavala Fortress. This intriguing castle is a must-visit for travelers looking for a unique holiday experience. Make your way to Holy Baptistery Of Saint Lydia Of Philippi located in Kavala Prefecture for another exciting encounter.

Next, immerse yourself in the setting of Archaeological Museum Of Philippi. Its heritage-rich features will captivate you. After the museum, continue your tour of the city with a visit to Ancient Theatre Of Philippi. Visitors usually appreciate the UNESCO world heritage-listed features of this archeological site.

At the end of the day, you will drive to Thessaloniki, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Thessaloniki is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Thessaloniki.

Enjoy a delicious meal at Enoches Bar, a top-rated dining destination in Thessaloniki. If you're in the mood to try something new, consider O Loytros, another top spot with a mouthwatering menu. You might also want to secure a reservation at rOOTS. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Thessaloniki this evening.

After your meal, keep the night alive at a bar like Peiratis Cafe-bar, known for its lively atmosphere. In Rock Cafe Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Tribeca offers an excellent atmosphere for those looking to amp up the evening.

Take some time to reflect on your day and savor another beautiful night in Greece.

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Day5

Day 5

  • Thessaloniki - Departure day
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  • The Umbrellas by Zongolopoulos
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Day 5 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting The Umbrellas Sculpture By Zogolopoulos, a visually striking art installation before you head out.

Take some time to indulge in shopping at Thessaloniki’s popular marketplace, Modiano Market. Look for keepsakes or souvenirs to remind you of your trip.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

If you're in the mood to try something new, consider Agora Ouzeri, another top spot with a mouthwatering menu.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
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Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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