5-Day Greece Road Trip from Thessaloniki traveling south to Trikala

Your road trip adventure in Greece begins as soon as you reach Thessaloniki and pick up your car. You’ll stay in Thessaloniki for 2 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Thessaloniki is a beautiful city with plenty to discover. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Thessaloniki. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat in Thessaloniki. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Have a delightful culinary experience when you dine at Kanoula. Favored by many foreign travelers and locals, this restaurant in Thessaloniki boasts a carefully curated and enticing menu. Its delectable dishes have earned it an impressive rating of 4.8 out of 5 stars from around 2,335 visitors.

Another dining spot you shouldn’t miss while in Thessaloniki is rOOTS. It has garnered a rating of 4.7 out of 5 stars from 2,104 diners thanks to its impeccable menu options and flavors.

Experience a celebration of flavors when you dine in at Kitchen Bar, in Thessaloniki. Its delightful menu and flavorful dishes have earned it a stellar rating of 4.3 out of 5 stars from 9,067 satisfied customers.

After your meal, consider going for a drink to celebrate this wonderful night in Greece. One of the best bars in the city is Pulp. This bar has an average rating of 4.7 out of 5 stars by 1,573 customers.

To gain one of the best bar experiences in Thessaloniki, we recommend the cocktails at Wall by Wall. This bar has been rated an average of 4.5 out of 5 stars by 4,128 customers and is an excellent place to make local friends.

Another of the best spots to experience the nightlife scene in Thessaloniki is Loupino Restaurant. This bar has an average rating of 4.4 out of 5 stars by 3,657 customers.

Raise a toast to the start of your 5-day road trip in Greece!

On day 2 of your road trip, you will have an entire day to explore Thessaloniki. You’ll stay in Thessaloniki for 1 night and discover all the best things to see and do in the area.

Your discoveries in Thessaloniki do not have to stop there. Check out the fantastic selection of tours and tickets offered in Thessaloniki on this day of your trip. You can select your tours below.

As dinnertime approaches, it's time to head out for a bite to eat in Thessaloniki. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Make a reservation at Giok Balik, a popular dining spot in Thessaloniki. Its reputation for being a popular dining spot shines through its 4.4 out of 5-star rating from 4,336 satisfied diners.

Make a reservation at Sebriko while indulging in the charm of Thessaloniki. This restaurant offers a delicious menu reflected with a rating of 4.6 out of 5 stars, cherished by 2,978 discerning connoisseurs.

Indulge in the flavors of Charoupi, a treasured establishment in Thessaloniki. Its diverse menu promises to tantalize your palate and elevate your dining experience. Known for its exceptional service, it has earned a 4.6 out of 5-star rating from 2,912 satisfied guests.

After dinner, visit Tribeca, which is considered one of the best bars in the city. This bar is rated an average of 4.4 out of 5 stars by 3,262 customers.

You can also enjoy drinks at a popular place like Castra- All Day Terrace Bar. This bar has an average rating of 4.5 out of 5 stars by 2,882 customers.

Alternatively, check out The Blue Cup | Creative bar. This bar is rated an average of 4.6 out of 5 stars by 2,254 customers.

Raise your glass and celebrate another amazing day of your road trip in Greece!

On day 3 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 2 destinations, Thessaloniki and Trikala. When you’re not sightseeing, take time to relax at your selected hotel in Trikala, where you’ll be staying for 1 night.

When you arrive, enjoy some sightseeing.

When you’re done exploring for the day, you’ll drive to Trikala, where you'll have a hotel waiting for you. Check in and spend some time relaxing before you head out to explore the city.

Indulge in a memorable dining experience at one of Trikala's most popular restaurants, and connect with friendly locals for an authentic adventure.

Make sure to book a table at Ouzo Vasilis, a popular restaurant in Trikala. This acclaimed restaurant and its mouthwatering dishes have earned the admiration of food lovers. Its commitment to culinary excellence is evident in its 4.7 out of 5-star rating from 972 satisfied guests.

Do not miss the opportunity to dine at Το Χάνι during your stay in Trikala. This popular dining spot boasts a tantalizing menu, earning a remarkable rating of 4.6 out of 5 stars, esteemed by 2,894 satisfied guests.

Savor the flavors of Palia Istoria, a renowned dining destination in Trikala. Offering a menu that's sure to please, it has a gained 4.5 out of 5-star rating from 1,654 satisfied guests.

One of the best bars in Trikala you could visit tonight after your dinner is Κρύπτη Μπαρ. This bar has an average rating of 4.7 out of 5 stars by 620 customers.

Another popular bar in the city is Bonjour Cafe Trikala. This bar is rated an average of 4.3 out of 5 stars by 1,081 customers.

Locals also enjoy Ivy. This bar has an average rating of 4.6 out of 5 stars by 766 customers.

Head back to your accommodation in Trikala and get some rest in preparation for another magical day of your road trip in Greece!

Embark on another extraordinary experience on day 4 of your road trip in Greece, where you’ll be making 3 stops. Today you will experience some of the highlights of this tour package, that is, the wonderful destinations of Trikala, Kastraki, and Thessaloniki. At the end of the day, you will enjoy the comforts of a top-rated hotel in Thessaloniki. Thessaloniki will be your home away from home for 1 night.

Be one of the day’s first visitors at Trikala City Center Square. This park is rated an average of 4.7 out of 5 stars by 3,972 visitors.

When you’re finished at Trikala City Center Square, head to Matsopoulos Park. This one-of-a-kind park is rated an average of 4.7 out of 5 stars in 8,887 reviews.

Kalambaka’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Trikala behind. This drive usually takes around 37 min. Kalambaka welcomes you with a multitude of unique vacation experiences.

Thessaloniki’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Kalambaka behind. This drive usually takes around 2 hours 43 min. Thessaloniki welcomes you with a multitude of unique vacation experiences.

At the end of the day, you will drive to Thessaloniki, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Thessaloniki.

Have a delightful culinary experience when you dine at The Rouga. Favored by many foreign travelers and locals, this restaurant in Thessaloniki boasts a carefully curated and enticing menu. Its delectable dishes have earned it an impressive rating of 4.6 out of 5 stars from around 2,900 visitors.

Another dining spot you shouldn’t miss while in Thessaloniki is The Greek. It has garnered a rating of 4.5 out of 5 stars from 3,117 diners thanks to its impeccable menu options and flavors.

Experience a celebration of flavors when you dine in at Palati Thessaloniki, in Thessaloniki. Its delightful menu and flavorful dishes have earned it a stellar rating of 4.4 out of 5 stars from 2,775 satisfied customers.

Menta is a fantastic bar many locals in Thessaloniki recognize. This popular bar is an excellent place to unwind after a busy day and is rated an average of 4.6 out of 5 stars by 2,241 customers.

You can also enjoy a few drinks and some snacks at Apallou, another popular bar in the city. This bar has an average rating of 4.4 out of 5 stars from 2,504 customers.

Kafodeio Greek is a local favorite and a great place to hang out and socialize with other travelers in Thessaloniki. Customers have rated the exciting Kafodeio Greek an average of 4.6 out of 5 stars in 2,095 reviews.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Greece.

Day 5 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

As your final day in Greece unfolds, don’t miss the chance for a last-minute shopping spree in Thessaloniki’s shopping district. Your accommodation’s convenient location near the city’s shopping area offers the luxury of time, so you don’t have to limit yourself from leisurely strolling its streets amidst a collection of establishments.

Look for the perfect gift for your loved ones back home, or buy yourself a little keepsake to remind you of Greece.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!