6-Day Greece Self-Drive Road Trip With Itinerary from Preveza to Ioannina and Patras and surrounding area

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Photo of aerial panoramic view of the historical castle of Pantokrator. Its one of the 3 castles in Preveza city located at the south end of the old city, near the beach of Kyani Akti.
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Explore the best of Greece on a remarkable 6-day road trip! Combine exploration with relaxation on a self-drive tour featuring Pantokratoras, Preveza, Mesopotamo, Kanallaki, Glyki, Kamarina, Ioannina, Perama, Neo Bizani, Patras, Kastria, Zachlorou, Antirio, Nafpaktos, Mesolongi, and Agrinio.

This perfectly planned road trip itinerary takes you through some of the best places to see in Greece. You will spend 2 nights in Preveza, 1 night in Ioannina, and 2 nights in Patras. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Preveza, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. Αcheron Springs and Ioannina Castle are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Pantokratoras, Preveza, Mesopotamo, Kanallaki, Glyki, Kamarina, Ioannina, Perama, Neo Bizani, Patras, Kastria, Zachlorou, Antirio, Nafpaktos, Mesolongi, and Agrinio, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day1

Day 1

  • Preveza - Arrival day
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  • Pantokratoras promenade
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Say hello to Preveza! Your exciting road trip through Greece is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Preveza for 1 night before you continue your adventure!

Preveza is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Pantokratoras Promenade. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Preveza. Check-in typically starts around 2 to 4 PM at hotels in Greece. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Preveza, it's often a good idea to reserve a table in advance.

Dine in style at Ano Vlanto (Ano Vlanto), a top recommendation for dinner tonight. Or, for a change of pace, Ventura Tavern boasts a menu that's sure to impress. Also, be sure to check out Monolithi Beach Bar. Known as a local hotspot, it’s a great choice for tonight in Preveza.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Roloi stands out as an excellent choice for a post-dinner cocktail. Alternatively, Markus Espresso & Wine Bar offers an ideal atmosphere to enjoy the pleasures of the night. Metropolis Cafe (mitropolis Kafe) is also a great option that provides a perfect setting for a relaxing evening.

Raise a toast to the start of your 6-day road trip in Greece!

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Day2

Day 2

  • Preveza
  • Mesopotamo
  • Kanallaki
  • Glyki
  • Ioannina
  • More

Drive 209 km, 3 hours 32 min

  • Necromanteion of Acheron
  • Αcheron Springs
  • Acheron Springs - Canyon Acheron
  • More

Experience an unparalleled adventure on day 2 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 4 places, which are Mesopotamo, Kanallaki, Glyki, and Kamarina. At the end of the day, you will retreat to the hotel of your choice in Ioannina, where will spend 1 night.

When you’ve had your share of Preveza, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Mesopotamo. Your travel time is around 36 min.

Spend your afternoon discovering Necromanteion Of Acheron, a worthwhile archeological site known for its culturally significant features.

When you’ve had your share of Mesopotamo, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Kanallaki. Your travel time is around 22 min.

For a more meaningful self-guided tour of the village's best attractions, visit Αcheron Springs, a well-known hiking area that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Glyki may take around 8 min. Upon your arrival in Glyki, you’ll be greeted with the opportunity to do some sightseeing and exploring.

One of our top recommendations for your sightseeing is Acheron Springs - Canyon Acheron. Spend some time admiring the eye-catching features of the canyon before you continue to your next stop.

At the end of the day, you will drive to Ioannina, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ioannina, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at To Dodeka Cafe Bar, an iconic dining spot in Ioannina. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Mustagogia, a popular restaurant in Ioannina. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Accademia Del Panino, a hidden gem nestled in Ioannina. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your meal, keep the night alive at a bar like ⚜ V E D E M A ⚜, known for its lively atmosphere. Hogwarts Tales And Spirits is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Chevalier offers an excellent atmosphere for those looking to amp up the evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Greece.

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Day3

Day 3

  • Ioannina
  • Perama
  • Neo Bizani
  • Patras
  • More

Drive 235 km, 3 hours 18 min

  • The Clock Tower of Ioannina
  • Ioannina Castle
  • Ich Kale Acropolis of Ioannina
  • Cave of Perama
  • Vrellis Greek History Museum (Wax Museum)
  • More

Your itinerary for day 3 of your road trip in Greece includes 3 stops and features some of the highlights of Ioannina, Perama, and Neo Bizani. At the end of the day, enjoy the comforts of a top-rated hotel in Patras, where you'll spend 2 nights.

Look forward to a unique sightseeing adventure at the worthwhile The Clock Tower Of Ioannina and allow yourself time to explore. Just a short distance away you'll find your next stop, Ioannina Castle, a visually striking castle that draws visitors from far and near.

Continue your journey to Ic Kale Acropolis Of Ioannina, one of the city’s most up-and-coming spots that you shouldn’t miss.

Perama’s wonders await as you prepare for another journey on the road, leaving the breathtaking surroundings of Ioannina behind. This drive usually takes around 11 min. Perama welcomes you with a multitude of unique vacation experiences.

Savor the day by heading to Cave Of Perama, an often recommended cave that draws visitors from near and far.

Embrace the thrill of the open road as you wave goodbye to Perama and set your GPS to Neo Bizani. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 30 min. Upon reaching Neo Bizani, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

When you're ready for some sights, head to Moyseio Ellinikis Istorias Payloy Vrelli, a beloved museum in Neo Bizani. Explore its detailed features at your own pace before you continue your journey.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Patras. Patras offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Patras's best restaurants.

Treat yourself to a delightful dinner at Tag, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Bianco? It's another excellent option with a diverse menu. Consider reserving a table at Carousello as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Patras.

To truly maximize your evening out, consider visiting Sofita after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Charama Therino, another bar with an inviting ambiance. Similarly, Notos also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Relax and look forward to more memorable moments to come!

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Day4

Day 4

  • Patras
  • Kastria
  • Zachlorou
  • More

Drive 213 km, 3 hours 54 min

  • Cave Lakes - Kastria Cave
  • Mega Spileon Monastery
  • Church of Agios Andreas
  • Patras' South Park - Notio Parko Patras
  • More

On day 4 of your road trip, you’ll start and end your day in Patras, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate city, including Kastria, Zachlorou, and Patras.

Look forward to a unique sightseeing adventure at the often recommended Holy Church Of Saint Andrew and allow yourself time to explore. Just a short distance away you'll find your next stop, Patras' South Park - Notio Parko Patras, an instagrammable park that draws visitors from far and near.

When you’ve had your share of Patras, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Kastria. Your travel time is around 1 hour 44 min.

Savor the day by heading to Cave Lakes - Kastria Cave, an increasingly popular cave that draws visitors from near and far.

After soaking in Kastria’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Zachlorou. Expect your car journey to take a minimum of 35 min. When you arrive in Zachlorou, it's time to take a break from the road.

Spend your afternoon discovering Mega Spileon Monastery, a frequently visited monastery known for its picture-perfect features.

When you’re done exploring for the day, you’ll return to Patras and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Patras, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Fork, a highly-rated dining destination in Patras. If you're eager to try something different, consider Flouskounis food, another top spot with a tantalizing menu. You might also want to secure a reservation at Big Ben. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Patras this evening.

Continue your evening by exploring the vibrant nightlife scene at Minimal, a prime destination for a thrilling night out. Also, don’t forget to check out Beer Bar Q, a bar that offers unique local touches. Likewise, Distinto Mall provides an excellent alternative for a fun evening.

Take some time to reflect on your day and savor another beautiful night in Greece.

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Day5

Day 5

  • Patras
  • Antirio
  • Naypaktos
  • Mesolongi
  • Preveza
  • More

Drive 188 km, 3 hours 10 min

  • Rion-Antirion Bridge
  • Psani
  • History and Art Museum of Messolonghi
  • Garden of Heroes
  • More

On day 5 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 4 destinations, including Antirio, Nafpaktos, Mesolongi, and Agrinio. When you’re not sightseeing, take time to relax at your chosen hotel in Preveza, where you’ll be staying for 1 night.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Antirio. This drive usually takes around 15 min, without any stops or traffic disruptions.

One of our top recommendations for your sightseeing is Charilaos Trikoupis Rio - Antirrio Bridge. Spend some time admiring the picture-perfect features of the monument before you continue to your next stop.

Set your GPS to Nafpaktos and hit the road. Expect a journey of approximately 10 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Nafpaktos beckons with new experiences!

Enjoy sightseeing at your own pace and allow yourself time to explore the beautiful surroundings. Take your self-guided tour to Psani, an increasingly popular beach that everyone visiting Nafpaktos should see.

When you’ve had your share of Nafpaktos, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Mesolongi. Your travel time is around 38 min.

History And Art Museum Of Messolonghi is a worthwhile museum we recommend visiting today. Discover its standout features before continuing your self-guided tour to Garden Of Heroes, a culturally significant cemetery that’s well-regarded in the area.

When you’re done exploring for the day, you’ll drive to your hotel in Preveza. Check in and relax before you head out to tour the city.

Preveza is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Preveza.

Enjoy a delicious meal at Treli Garida, a highly-rated dining destination in Preveza. If you're eager to try something different, consider Alati Seafood & More, another top spot with a tantalizing menu. You might also want to secure a reservation at Saitan Bazaar - Saitan Pazar. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Preveza this evening.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Hipster Cafe, a well-loved spot among locals and tourists. Or, head to Adesso. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Art Cafe "botilia Sto Pelago", another top-rated place in the area.

Say good night to Preveza and look forward to another great day of your road trip in Greece!

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Day6

Day 6

  • Preveza - Departure day
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Day 6 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Preveza before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

For a last-minute shopping spree in Preveza, Preveza Marina is nearby. Enjoy a variety of retail stores, dining options, and essential services in one convenient location. Browse through boutiques to find unique and stylish fashion pieces to take home.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Preveza.

Have a fantastic dining experience at Symposio, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Prevere Cafe bar offers an enticing alternative with its varied menu.

You’ll then say farewell to Preveza. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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