6-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling west to Kalambaka

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Photo of bird's eye view to the promenade of Thessaloniki.
Photo of Saint Paul cathedral in Thessaloniki, Greece.
6-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling west to Kalambaka
6-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling west to Kalambaka
6-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling west to Kalambaka
6-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling west to Kalambaka
6-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling west to Kalambaka
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Escape the ordinary with this exciting 6-day road trip through Greece. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Greece. You will spend 3 nights in Thessaloniki and 2 nights in Kalambaka. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Thessaloniki, Kalambaka, Kastraki, Trikala, Elassona, Dion, and Litochoro, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day1

Day 1

  • Thessaloniki - Arrival day
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  • Ladadika
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Your road trip adventure in Greece begins as soon as you reach Thessaloniki and pick up your car. You’ll stay here for 2 nights and explore what to see in Thessaloniki, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Thessaloniki is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Thessaloniki. Check-in typically starts around 2 to 4 PM at hotels in Greece. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Kitchen Bar, a top-rated dining destination in Thessaloniki. If you're in the mood to try something new, consider The Greek, another top spot with a mouthwatering menu. You might also want to secure a reservation at Phanós. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Thessaloniki this evening.

Continue the enjoyment post-dinner at Beetle Bar, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Vogatsikou 3 offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Souel. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Raise a toast to the start of your 6-day road trip in Greece!

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Day2

Day 2

  • Thessaloniki
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Drive 6 km, 53 min

  • Kapani
  • Aristotelous Square
  • Agias Sofias Square
  • Arch of Galerius
  • White Tower of Thessaloniki
  • Tsimiski Street
  • More

Day 2 of your road trip will take you to the best attractions Thessaloniki has to offer. Cherish the 1 night you have left in the city and use the provided itinerary to discover what to see in Thessaloniki.

Set aside time today to explore Tsimiski Street, a standout street that reflects the essence of the city. While you're there, you'll also be within reach of some of the city's top landmarks, making it easy to maximize your day.

Visiting Kapani is always a good idea. This locally renowned market is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the romantic wonders of Aristotelous Square, a must-see public square in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Agias Sofias Square. This locally renowned public square offers an enriching experience. For a change of pace, head to Arch Of Galerius And Rotunda, where you can take in heritage-rich features. Conclude your self-guided sightseeing tour with a visit to White Tower Of Thessaloniki These sights offer a fulfilling end to a perfect day.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Greece. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Thessaloniki's best restaurants.

Treat yourself to a delightful dinner at Mamalouka, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Clochard? It's another excellent option with a diverse menu. Consider reserving a table at Sofi's House Restaurant as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Thessaloniki.

Following your dinner, dive into the local bar culture at Castra- All Day Terrace Bar. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Barbaben - Bar/ba/ben, the perfect place for those looking to experience the best of the nightlife. Similarly, Apallou provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Relax and look forward to more memorable moments to come!

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Day3

Day 3

  • Thessaloniki
  • Meteora
  • Kastraki
  • More

Drive 246 km, 3 hours 25 min

  • Monastery of St Stephan
  • Meteora
  • Natural History Museum of Meteora and Mushroom Museum
  • Greek Education Museum
  • More

Dive into day 3 of your remarkable road trip in Greece. Today you'll explore 2 destinations, including Kalambaka and Kastraki. At the end of the day, you’ll unwind at one of the finest accommodations in Kalambaka, where you'll spend 2 nights.

Embrace the thrill of the open road as you wave goodbye to Thessaloniki and set your GPS to Kalambaka. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 2 hours 52 min. Upon reaching Kalambaka, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

One of our top recommendations for your sightseeing is Holy Monastery Of Saint Stephan. Spend some time admiring the historic features of the monastery before you continue to your next stop. Then, head to Natural History Museum Of Meteora And Mushroom Museum. This increasingly popular museum is a traveler-favorite in the town.

If you're keen to see more, continue to Greek Education Museum. Feed your curiosity by learning something new about the museum.

Set your GPS to Kastraki and hit the road. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Kastraki beckons with new experiences!

For a more meaningful self-guided tour of the town's best attractions, visit Meteora, a popular monastery that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey.

At the end of the day, you will drive to Kalambaka, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Kalambaka's best restaurants.

Take some time to reflect on your day and savor another beautiful night in Greece.

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Day4

Day 4

  • Meteora
  • Kastraki
  • Trikala
  • More

Drive 58 km, 1 hour 48 min

  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Monastery of Varlaam
  • Main Observation Deck of Meteora
  • Trikala City Center Square
  • Central Bridge
  • Matsopoulos Park
  • More

On day 4 of your road trip, you’ll start and end your day in Kalambaka, where you have 1 night left to stay.

When you’re ready to jump back into the car and say goodbye to Kalambaka, you’ll hit the road in the direction of Kastraki. This drive usually takes around 15 min.

When you're ready for some sights, head to Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour, a locally appreciated monastery in Kastraki. Explore its breathtaking features at your own pace before you continue your journey to your next attraction, Monastery Of Varlaam. This up-and-coming monastery is a top recommendation in the area.

When you’re ready to explore more, Main Observation Deck Of Meteora is an excellent choice. Spend some time discovering what some claim to be the most serene observation deck in the region.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Trikala may take around 30 min. Upon your arrival in Trikala, you’ll be greeted with the opportunity to do some sightseeing and exploring.

One of our top recommendations for your sightseeing is Trikala City Center Square. Spend some time admiring the romantic features of the public square before you continue to your next stop. Then, head to Central Bridge. This increasingly popular public square is a traveler-favorite in the village.

If you're keen to see more, continue to Matsopoulos Park. Feed your curiosity by learning something new about the park.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Kalambaka.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Kalambaka, it's often a good idea to reserve a table in advance.

Raise your glass and celebrate another amazing day of your road trip in Greece!

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Day5

Day 5

  • Meteora
  • Elassona
  • Dion
  • Litochoro
  • Thessaloniki
  • More

Drive 270 km, 4 hours 6 min

  • Kanalon Monastery
  • Archaeological Site of Dion
  • Archaeological Museum of Dion
  • Litochoro Center
  • More

On day 5 of your road trip in Greece, your travel plans include 3 stops at the most scenic, wondrous, and interesting places in the region. Elassona, Dion, and Litochoro are on today's agenda. In the evening, you’ll end up in Thessaloniki, where you will stay for 1 night.

When you’ve had your share of Kalambaka, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Elassona. Your travel time is around 1 hour 55 min.

Kanalon Monastery is a frequently visited monastery we recommend visiting today. Discover its picture-perfect features before continuing your self-guided tour.

After soaking in Elassona’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: Dion. Expect your car journey to take a minimum of 48 min. When you arrive in Dion, it's time to take a break from the road.

Spend your afternoon discovering Archaeological Park Of Dion, a beloved archeological site known for its breathtaking features. Next, continue your sightseeing at Archaeological Museum Of Dion, a worthwhile museum.

Continue your road trip and head to your next destination, Litochoro. This car ride takes around 11 min.

Savor the day by heading to Litochoro Center, an often recommended visitor center that draws visitors from near and far.

When you’re done exploring for the day, you’ll drive to your hotel in Thessaloniki. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Thessaloniki. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Don’t miss out on dining at Enoches Bar, a top-rated dining destination in Thessaloniki. If you're in the mood to try something new, consider O Loytros, another top spot with a mouthwatering menu. You might also want to secure a reservation at rOOTS. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Thessaloniki this evening.

Explore the vibrant nightlife at Peiratis Cafe-bar after your meal, a hub for lively evenings and memorable moments. Or, head to In Rock Cafe Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Tribeca is perfect for those looking to extend their night with a touch of local flavor.

As the sun sets, rest up and recharge for the next leg of your road trip in Greece.

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Day6

Day 6

  • Thessaloniki - Departure day
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  • The Umbrellas by Zongolopoulos
  • More

Day 6 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting The Umbrellas Sculpture By Zogolopoulos, an enchanting art installation before you head out.

Make the most of your final day in Greece by visiting Thessaloniki’s iconic markets and shopping establishments in the buzzing Tsimiski Street. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation. You can also browse through boutiques for stylish fashion choices.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
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Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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