7-Day Greece Self-Drive Road Trip With Itinerary from Ioannina traveling east to Kalambaka and Thessaloniki

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Photo of Ioannina lake Pamvotida in Epirus Region, Greece.
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Escape the ordinary with this exciting 7-day road trip through Greece. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 3 nights in Ioannina, 2 nights in Kalambaka, and 1 night in Thessaloniki. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Ioannina, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Meteora, learn more about the unique Arch Of Galerius And Rotunda, and immerse yourself in the vibrant atmosphere of Ioannina Castle.

As you hit the open road and drive through Ioannina, Perama, Kalambaka, Kastraki, Thessaloniki, Mandio, and Neo Bizani, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Ioannina Castle
Cave of PeramaMuseum "Arslan Pasha"Ich Kale Acropolis of IoanninaFethiye MosqueByzantine Museum of IoanninaSilversmithing Museum
Meteora Digital Projection CenterMonastery of St StephanMeteoraNatural History Museum of Meteora and Mushroom MuseumGreek Education Museum
The Great Meteoron Holy Monastery of the Transfiguration of the SaviourMonastery of VarlaamMain Observation Deck of Meteora
White Tower of ThessalonikiArchaeological Museum of ThessalonikiArch of GaleriusChurch of St DemetriosAristotelous Square
Archaeological Site of DodoniVrellis Greek History Museum (Wax Museum)
The Clock Tower of Ioannina

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Day 1

Day 1

  • Ioannina - Arrival day
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  • Ioannina Castle
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Welcome to Ioannina, the perfect starting point for your road trip in Greece! Pick up your rental car and let the adventure begin. You will spend 2 nights immersing yourself in Ioannina's charm before embarking on the next leg of your journey.

Ioannina is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ioannina Castle, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Ioannina. Check-in typically starts around 2 to 4 PM at hotels in Greece. We recommend staying at a hotel in a central location for easy access to the best attractions, restaurants, and bars in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ioannina, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at To Dodeka Cafe Bar, a highly-rated dining destination in Ioannina. If you're eager to try something different, consider Mustagogia, another top spot with a tantalizing menu. You might also want to secure a reservation at Accademia Del Panino. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Ioannina this evening.

Keep the excitement of the evening going by visiting a bar or two. ⚜ V E D E M A ⚜ is an excellent place to start. You could also check out Hogwarts Tales And Spirits, offering a different kind of charm. A last recommendation for the day is Chevalier. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Raise a toast to the start of your 7-day road trip in Greece!

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Day 2

Day 2

  • Ioannina
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Drive 11 km, 38 min

  • Cave of Perama
  • Museum "Arslan Pasha"
  • Ich Kale Acropolis of Ioannina
  • Fethiye Mosque
  • Byzantine Museum of Ioannina
  • Silversmithing Museum
  • More

Greet day 2 of your road trip in Greece with a smile and start your day with a hearty breakfast. You will return to Ioannina for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Perama and Ioannina.

Today’s route brings fun adventures, natural wonders, and scenic views. The first attraction of today is Cave Of Perama. This intriguing cave is a scenic place to see in Ioannina.

As you stroll around Ioannina, take in the distinct atmosphere and learn what makes this town so unique. Maximize your sightseeing with a visit to Ic Kale Acropolis Of Ioannina. This worthwhile archeological site offers a stunning encounter with Ioannina. Next, make your way to Fethiye Mosque to add another highlight to your day. After that, visit Byzantine Museum Of Ioannina, an underrated museum that’s sure to impress. If you’re up for more, end your self-guided sightseeing tour at Silversmithing Museum Of Ioannina, an often recommended museum in the town. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Ioannina.

When you’re done exploring for the day, you’ll return to Ioannina and your accommodation.

Indulge in a memorable dining experience at one of Ioannina's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a lovely dining experience at Spitaki me thea, a popular restaurant in Ioannina. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Ioannina at Frontzoy Politeia - Frontzu Politia Restaurant, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Papi Cafe Bistro. It’s yet another ideal choice to enhance your time in Ioannina tonight.

Following your dinner, dive into the local bar culture at Scala. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Route 66 Bar, the perfect place for those looking to experience the best of the nightlife. Similarly, Palia Agora provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Relax and reminisce about your day in Greece and look forward to more memorable moments to come!

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Day 3

Day 3

  • Ioannina
  • Meteora
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Drive 122 km, 2 hours 27 min

  • Meteora Digital Projection Center
  • Monastery of St Stephan
  • Meteora
  • Natural History Museum of Meteora and Mushroom Museum
  • Greek Education Museum
  • More

Dive into day 3 of your remarkable road trip in Greece. Today you will explore Kalambaka and Kastraki, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Kalambaka. You’ll stay here for 2 nights.

Today, you'll explore some of the most beautiful places in Ioannina, including a visitor center, a monastery, and a museum. Start your day with a visit to Meteora Digital Projection Center. This increasingly popular visitor center is a must-visit in the town. When you’re ready for your next discovery, continue to Holy Monastery Of Saint Stephan, which may be one of the most breathtaking places you will experience today.

One of the best things about exploring Ioannina on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Meteora, a well-known monastery in the town. If you’re up for more discoveries, don’t forget to reserve some time for Natural History Museum Of Meteora And Mushroom Museum and Greek Education Museum.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Kalambaka. Kalambaka offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Kalambaka, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Say good night to Kalambaka and look forward to another great day of your road trip in Greece!

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Day 4

Day 4

  • Meteora
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Drive 16 km, 43 min

  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Monastery of Varlaam
  • Main Observation Deck of Meteora
  • More

On day 4 of your road trip in Greece, you’ll start and end your day in Kalambaka, but spend the day exploring what’s beyond the town. Since you will return to Kalambaka for 1 night more, there’s no need to rush. Experience Kastraki to the fullest today with this curated day itinerary!

Today, you'll explore some of the most beautiful places in Kalambaka, including a monastery and an observation deck. Start your day with a visit to Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour. This up-and-coming monastery is a must-visit in the village. When you’re ready for your next discovery, continue to Monastery Of Varlaam, which may be one of the most historic places you will experience today.

One of the best things about exploring Kalambaka on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Main Observation Deck Of Meteora, a frequently visited observation deck in the village.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Kalambaka.

As you explore more of Kalambaka, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Greece.

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Day 5

Day 5

  • Meteora
  • Thessaloniki
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Drive 240 km, 3 hours 42 min

  • White Tower of Thessaloniki
  • Archaeological Museum of Thessaloniki
  • Arch of Galerius
  • Church of St Demetrios
  • Aristotelous Square
  • More

On day 5 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 1 destination, Thessaloniki. When you’re not sightseeing, take time to relax at your selected hotel in Thessaloniki, where you’ll be staying for 1 night.

Savor the day by visiting some of the best places to see in Kalambaka, including a monument, a museum, a church, a public square and much more! Start your adventure at White Tower Of Thessaloniki. This famous monument is a must-visit for travelers looking for a unique holiday experience. Make your way to Archaeological Museum Of Thessaloniki located in Kalambaka for another exciting encounter.

Next, immerse yourself in the setting of Arch Of Galerius And Rotunda. Its culturally significant features will captivate you. After the monument, continue your tour of the city with a visit to Holy Church Of Saint Demetrius, Patron Saint Of Thessalonica. Visitors usually appreciate the culturally significant features of this church. Next up is Aristotelous Square, a highly recommended public square.

At the end of the day, you will drive to Thessaloniki, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Thessaloniki. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Don’t miss out on dining at Kitchen Bar, a top-rated dining destination in Thessaloniki. If you're in the mood to try something new, consider The Greek, another top spot with a mouthwatering menu. You might also want to secure a reservation at Phanós. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Thessaloniki this evening.

After enjoying a fulfilling meal, continue your evening at Beetle Bar, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Vogatsikou 3 offers a welcoming atmosphere for easing into the nightlife. Similarly, Souel provides an excellent environment for a relaxed and enjoyable evening.

Raise your glass and celebrate another amazing day of your road trip in Greece!

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Day 6

Day 6

  • Thessaloniki
  • Ioannina
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Drive 293 km, 3 hours 23 min

  • Archaeological Site of Dodoni
  • Vrellis Greek History Museum (Wax Museum)
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Experience an unparalleled adventure on day 6 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Mandio and Neo Bizani. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Ioannina. You will spend 1 night here for some well-deserved relaxation.

Set out on a day brimming with family-friendly attractions, scenic views, and picturesque spots. Start at the frequently visited Archaeological Site Of Dodoni, a picture-perfect archeological site in Thessaloniki. Next, go to Moyseio Ellinikis Istorias Payloy Vrelli.

When you’re done exploring for the day, you’ll drive to your hotel in Ioannina. Check in and spend some time relaxing before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Ioannina's best restaurants.

Treat yourself to a wonderful meal at PRESVEIA Restaurant Meze, a top-rated dining spot in Ioannina. If you're in the mood for something new, try Frontzu Politia - Hotel, another premier location with a delectable menu. You might also want to book a table at Equus. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Ioannina.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Spitaki, known for its inviting atmosphere. American Bar is another great option if you’re looking for a place to get the night started. Similarly, Olympic provides a great setting to enjoy the night away.

Take some time to reflect on your day and savor another beautiful night in Greece.

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Day 7

Day 7

  • Ioannina - Departure day
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  • The Clock Tower of Ioannina
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Day 7 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Ioannina before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at The Clock Tower Of Ioannina. This underrated monument is a popular place to see in the city.

Make the most of your final day in Greece by visiting Ioannina’s iconic markets and shopping establishments in the buzzing Epirus Street. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Greece. You can also browse through boutiques for stylish fashion choices. Savor your final moments in Greece at a cozy cafe while relaxing with a cup of coffee or tea.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Ioannina.

If you're eager to try something different, consider Motley Coffeesweet, another top spot with a tantalizing menu.

You’ll then say farewell to Ioannina. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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