7-Day Greece Self-Drive Road Trip With Itinerary from Ioannina traveling east to Kalambaka and Thessaloniki

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Photo of Ioannina lake Pamvotida in Epirus Region, Greece.
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Escape the ordinary with this exciting 7-day road trip through Greece. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Greece. You will spend 3 nights in Ioannina, 2 nights in Kalambaka, and 1 night in Thessaloniki. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Ioannina, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Meteora, learn more about the unique Arch Of Galerius And Rotunda, and immerse yourself in the vibrant atmosphere of Ioannina Castle.

As you hit the open road and drive through Ioannina, Perama, Kalambaka, Kastraki, Thessaloniki, Mandio, and Neo Bizani, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day 1

Day 1

  • Ioannina - Arrival day
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  • Ioannina Castle
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Your road trip adventure in Greece begins as soon as you reach Ioannina and pick up your car. You’ll stay here for 2 nights and explore what to see in Ioannina, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Ioannina is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ioannina Castle, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Ioannina. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Greece. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ioannina, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at To Dodeka Cafe Bar, an iconic dining spot in Ioannina. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Mustagogia, a popular restaurant in Ioannina. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Accademia Del Panino, a hidden gem nestled in Ioannina. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your meal, keep the night alive at a bar like ⚜ V E D E M A ⚜, known for its lively atmosphere. Hogwarts Tales And Spirits is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Chevalier offers an excellent atmosphere for those looking to amp up the evening.

Raise a toast to the start of your 7-day road trip in Greece!

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Day 2

Day 2

  • Ioannina
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Drive 11 km, 38 min

  • Cave of Perama
  • Museum "Arslan Pasha"
  • Ich Kale Acropolis of Ioannina
  • Fethiye Mosque
  • Byzantine Museum of Ioannina
  • Silversmithing Museum
  • More

On day 2 of your road trip, you’ll start and end your day in Ioannina, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate city, including Perama and Ioannina.

Catch Cave Of Perama before the crowds roll in. This scenic cave is sure to ignite your curiosity.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Ic Kale Acropolis Of Ioannina, a frequently visited archeological site. For a change of scene, check out Fethiye Mosque, known for its breathtaking features. We also recommend visiting Byzantine Museum Of Ioannina. This museum is a must for anyone looking to experience the town to the fullest. Lastly, end your day with a visit to Silversmithing Museum Of Ioannina, yet another curiosity-inducing attraction in Ioannina.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Ioannina.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Ioannina. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a delicious meal at Spitaki me thea, a top-rated dining destination in Ioannina. If you're in the mood to try something new, consider Frontzoy Politeia - Frontzu Politia Restaurant, another top spot with a mouthwatering menu. You might also want to secure a reservation at Papi Cafe Bistro. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Ioannina this evening.

After enjoying a fulfilling meal, continue your evening at Scala, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Route 66 Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Palia Agora provides an excellent environment for a relaxed and enjoyable evening.

Say good night to Ioannina and look forward to another great day of your road trip in Greece!

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Day 3

Day 3

  • Ioannina
  • Meteora
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Drive 122 km, 2 hours 27 min

  • Meteora Digital Projection Center
  • Monastery of St Stephan
  • Meteora
  • Natural History Museum of Meteora and Mushroom Museum
  • Greek Education Museum
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Dive into day 3 of your remarkable road trip in Greece. Today you'll explore 2 destinations, including Kalambaka and Kastraki. At the end of the day, you’ll unwind at one of the finest accommodations in Kalambaka, where you'll spend 2 nights.

Your adventure in Ioannina is only getting started when you visit Meteora Digital Projection Center, an intriguing local hot spot. Another notable attraction to explore is Holy Monastery Of Saint Stephan.

After soaking in the highlights of these sights, take some time to wander Ioannina's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Meteora. This inviting monastery offers a fascinating experience that many visitors find memorable. Natural History Museum Of Meteora And Mushroom Museum is also worth visiting, along with Greek Education Museum. These standout landmarks offer unique experiences that add to the day’s enjoyment.

At the end of the day, you will drive to Kalambaka, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Kalambaka's most popular restaurants, and connect with friendly locals for a true cultural experience.

Known for great service, it’s a fantastic choice for tonight in Kalambaka.

Take some time to reflect on your day and savor another beautiful night in Greece.

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Day 4

Day 4

  • Meteora
  • More

Drive 16 km, 43 min

  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Monastery of Varlaam
  • Main Observation Deck of Meteora
  • More

Wake up to day 4 of your road trip in Greece. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Kastraki. With 1 night to stay in Kalambaka, we encourage you to seize the day and discover the unexplored beauty of the town’s surroundings!

To truly experience Kalambaka, make sure to drop by Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour. This worthwhile monastery is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Monastery Of Varlaam, one of the village’s best highlights.

Next, check out Main Observation Deck Of Meteora, one of the most intriguing places to see in Kalambaka. This observation deck is a favorite among locals and travelers alike.

When you’re done exploring for the day, you’ll return to Kalambaka and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Kalambaka. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Raise your glass and celebrate another amazing day of your road trip in Greece!

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Day 5

Day 5

  • Meteora
  • Thessaloniki
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Drive 240 km, 3 hours 42 min

  • White Tower of Thessaloniki
  • Archaeological Museum of Thessaloniki
  • Arch of Galerius
  • Church of St Demetrios
  • Aristotelous Square
  • More

Your itinerary for day 5 of your road trip in Greece includes 1 stop and features some of the highlights of Thessaloniki. At the end of the day, enjoy the comforts of a top-rated hotel in Thessaloniki, where you'll spend 1 night.

White Tower Of Thessaloniki is an ideal stop early in the day. This extraordinary monument is a must-visit in the city. When you’re ready for your next discovery, continue to Archaeological Museum Of Thessaloniki, which may be one of the most eye-catching places you will experience today.

One of the best things about exploring Kalambaka on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Arch Of Galerius And Rotunda, a well-known monument in the city. If you’re up for more discoveries, don’t forget to reserve some time for Holy Church Of Saint Demetrius, Patron Saint Of Thessalonica and Aristotelous Square.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Thessaloniki. Thessaloniki offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Thessaloniki is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Thessaloniki.

Make sure to reserve a table at Kitchen Bar, an iconic dining spot in Thessaloniki. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of The Greek, a popular restaurant in Thessaloniki. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Phanós, a hidden gem nestled in Thessaloniki. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Following your dinner, dive into the local bar culture at Beetle Bar. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Vogatsikou 3, the perfect place for those looking to experience the best of the nightlife. Similarly, Souel provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Celebrate another amazing day of your road trip adventure in Greece!

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Day 6

Day 6

  • Thessaloniki
  • Ioannina
  • More

Drive 293 km, 3 hours 23 min

  • Archaeological Site of Dodoni
  • Vrellis Greek History Museum (Wax Museum)
  • More

Experience an unparalleled adventure on day 6 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Mandio and Neo Bizani. At the end of the day, you will retreat to the hotel of your choice in Ioannina, where will spend 1 night.

To truly experience Thessaloniki, make sure to drop by Archaeological Site Of Dodoni. This increasingly popular archeological site is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Moyseio Ellinikis Istorias Payloy Vrelli, one of the village’s best highlights.

When you’re done exploring for the day, you’ll drive to your hotel in Ioannina. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Ioannina's best restaurants.

Have a fantastic dining experience at PRESVEIA Restaurant Meze, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Frontzu Politia - Hotel offers an enticing alternative with its varied menu. Additionally, Equus is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Ioannina.

After enjoying a fulfilling meal, continue your evening at Spitaki, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, American Bar offers a welcoming atmosphere for easing into the nightlife. Similarly, Olympic provides an excellent environment for a relaxed and enjoyable evening.

Raise your glass to another unforgettable day in Greece!

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Day 7

Day 7

  • Ioannina - Departure day
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  • The Clock Tower of Ioannina
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Day 7 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Ioannina before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting The Clock Tower Of Ioannina, a picture-perfect monument before you head out.

For a shopping spree in Ioannina, we recommend the lively Epirus Street. Here, you'll find a range of shops you can browse for some souvenir shopping. Discover boutiques with stylish fashion choices to upgrade your wardrobe. Take one last moment to soak in Greece, and unwind with tea or coffee at a cozy cafe.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Ioannina.

If you're in the mood for something new, try Motley Coffeesweet, another premier location with a delectable menu.

You’ll then say farewell to Ioannina. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
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Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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