7-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki to Kalambaka, Ioannina, and Metsovo

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Photo of Saint Paul cathedral in Thessaloniki, Greece.
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Experience the freedom of the open road on an unforgettable 7-day road trip in Greece! Embark on a self-drive tour that caters to every traveler, featuring destinations like Thessaloniki, Kastraki, Kalambaka, Perama, Ioannina, Anilio, Metsovo, and Vergina.

This perfectly planned road trip itinerary takes you through some of the best places to see in Greece. You will spend 3 nights in Thessaloniki, 1 night in Kalambaka, 1 night in Ioannina, and 1 night in Metsovo. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable The Umbrellas Sculpture By Zogolopoulos, learn more about the unique Arch Of Galerius And Rotunda, and immerse yourself in the vibrant atmosphere of Ioannina Castle.

As you hit the open road and drive through Thessaloniki, Kastraki, Kalambaka, Perama, Ioannina, Anilio, Metsovo, and Vergina, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day 1

Day 1

  • Thessaloniki - Arrival day
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  • Ladadika
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Your road trip adventure in Greece begins as soon as you reach Thessaloniki and pick up your car. You’ll stay here for 2 nights and explore what to see in Thessaloniki, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Thessaloniki is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ladadika, a must-see neighborhood, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Thessaloniki. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Kitchen Bar, a highly recommended choice for tonight's dinner. If you're looking to mix things up, The Greek offers an enticing alternative with its varied menu. Additionally, Phanós is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Thessaloniki.

If you’re not ready to end the night just yet, Beetle Bar offers a perfect venue to relax and savor a drink. Similarly, Vogatsikou 3 is well-suited for those looking to unwind in a social setting. Souel is another excellent spot to enjoy a nightcap after a delightful meal.

Raise a toast to the start of your 7-day road trip in Greece!

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Day 2

Day 2

  • Thessaloniki
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Drive 6 km, 59 min

  • The Umbrellas by Zongolopoulos
  • Museum of Byzantine Civilization
  • Archaeological Museum of Thessaloniki
  • White Tower of Thessaloniki
  • Aristotelous Square
  • Tsimiski Street
  • More

Day 2 offers an itinerary packed with the best things to see in Thessaloniki. You’ll stay in Thessaloniki for 1 night more, offering you enough time to explore at a relaxed pace.

Tsimiski Street is one of the highlights of today. Take your time exploring this iconic street in Thessaloniki, which offers a perfect blend of history and culture. Plus, it's close to many must-see landmarks in the city.

Let The Umbrellas Sculpture By Zogolopoulos set the tone for the day. Spend some time admiring this visually striking art installation before continuing your journey. Museum Of Byzantine Culture is your next stop. This underrated museum is one of the best-rated sights in Thessaloniki.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Archaeological Museum Of Thessaloniki. This visually striking museum is a sight to behold. To round off your sightseeing experience, visit White Tower Of Thessaloniki and Aristotelous Square.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Greece. You can explore and select activities under each day of your itinerary.

Thessaloniki is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Thessaloniki.

Dine in style at Mamalouka, a top recommendation for dinner tonight. Or, for a change of pace, Clochard boasts a menu that's sure to impress. Also, be sure to check out Sofi's House Restaurant. Known as a local hotspot, it’s a great choice for tonight in Thessaloniki.

Keep the evening going at Castra- All Day Terrace Bar, a great choice for enjoying the after-dinner hours with a drink. You could also go to Barbaben - Bar/ba/ben, which offers a similarly pleasant setting and great drinks. Another option is Apallou, which provides an inviting environment for unwinding after a busy day out.

Relax and recharge in preparation for another adventurous day in Greece!

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Day 3

Day 3

  • Thessaloniki
  • Meteora
  • More

Drive 240 km, 3 hours 33 min

  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Monastery of Varlaam
  • Main Observation Deck of Meteora
  • Natural History Museum of Meteora and Mushroom Museum
  • Greek Education Museum
  • More

Experience an unparalleled adventure on day 3 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Kastraki and Kalambaka. At the end of the day, you will retreat to the hotel of your choice in Kalambaka, where will spend 1 night.

Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour leaves a lasting impression. This monastery is one of the most beloved places to visit in Thessaloniki. Next, head to Monastery Of Varlaam, an often recommended monastery, known for its historic features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Main Observation Deck Of Meteora. This romantic observation deck is a highly recommended experience. Nearby, you'll also find Natural History Museum Of Meteora And Mushroom Museum and Greek Education Museum. Visit these for an interesting touch to your journey.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Kalambaka. Kalambaka offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Kalambaka, it's often a good idea to reserve a table in advance.

Say good night to Kalambaka and look forward to another great day of your road trip in Greece!

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Day 4

Day 4

  • Meteora
  • Ioannina
  • More

Drive 107 km, 2 hours 26 min

  • Cave of Perama
  • Silversmithing Museum
  • Ich Kale Acropolis of Ioannina
  • Ioannina Castle
  • Litharitsia park
  • The Clock Tower of Ioannina
  • More

Your itinerary for day 4 of your road trip in Greece includes 2 stops and features some of the highlights of Perama and Ioannina. At the end of the day, enjoy the comforts of a top-rated hotel in Ioannina, where you'll spend 1 night.

Enjoy all that Cave Of Perama has to offer. This is a curiosity-inducing cave you should not miss. Another must-see is Silversmithing Museum Of Ioannina, a locally appreciated museum in Kalambaka.

When you’re ready for the next sight, head to Ic Kale Acropolis Of Ioannina. From there, take a leisurely stroll to Ioannina Castle, another of the town’s popular attractions. We recommend continuing your self-guided tour at Litharitsia Park, a romantic place of interest in the town. If time allows, add The Clock Tower Of Ioannina to your itinerary. This beloved monument offers the perfect finishing touch to your day in Kalambaka.

When you’re done exploring for the day, you’ll drive to your hotel in Ioannina. Check in and relax before you head out to tour the city.

Ioannina is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Ioannina.

Enjoy a delicious meal at To Dodeka Cafe Bar, a top-rated dining destination in Ioannina. If you're in the mood to try something new, consider Mustagogia, another top spot with a mouthwatering menu. You might also want to secure a reservation at Accademia Del Panino. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Ioannina this evening.

To truly maximize your evening out, consider visiting ⚜ V E D E M A ⚜ after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Hogwarts Tales And Spirits, another bar with an inviting ambiance. Similarly, Chevalier also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Get a good night's sleep and look forward to another great day on the road in Greece!

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Day 5

Day 5

  • Ioannina
  • Metsovo
  • More

Drive 56 km, 1 hour 15 min

  • Καταρράκτης Ανήλιου
  • Αβερώφειος Κήπος
  • Metsovo Folk Art Museum (Tossizza Mansion)
  • Metsovo square
  • Averoff Art Gallery
  • More

On day 5 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 2 destinations, including Anilio and Metsovo. When you’re not sightseeing, take time to relax at your chosen hotel in Metsovo, where you’ll be staying for 1 night.

Your adventure in Ioannina is only getting started when you visit Katarraktis Anilioy, a frequently visited local hot spot. Another notable attraction to explore is Averofeios Kipos. This frequently visited park is known for its serene appeal.

After soaking in the highlights of these sights, take some time to wander Ioannina's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Metsovo Folk Art Museum (tossizza Mansion). This heritage-rich museum offers a fascinating experience that many visitors find memorable. Metsovo Square is also worth visiting, along with Averoff Art Gallery. These standout landmarks offer unique experiences that add to the day’s enjoyment.

At the end of the day, you will drive to Metsovo, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Metsovo. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a lovely meal at Ta 5 FFFFF, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Cafe Petrino is another top choice with a popular menu. You could also check for a table at Fame Metsovo. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Metsovo tonight.

After your meal, keep the night alive at a bar like Karma, known for its lively atmosphere. Krini Cafe Metsovo is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Stul Cafe offers an excellent atmosphere for those looking to amp up the evening.

Relax and recharge in preparation for another adventurous day in Greece!

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Day 6

Day 6

  • Metsovo
  • Thessaloniki
  • More

Drive 236 km, 2 hours 41 min

  • Polycentric Museum of Aigai (Aegae) - Main Building
  • Museum of the Royal Tombs at Aigai (Aegae)
  • Haliacmon Dam - Artificial Lake at Saint Barbara of Veria
  • More

Dive into day 6 of your remarkable road trip in Greece. Today you'll explore 1 destination, including Vergina. At the end of the day, you’ll unwind at one of the finest accommodations in Thessaloniki, where you'll spend 1 night.

Start your day at Polycentric Museum Of Aigai (aegae) - Main Building. This heritage-rich museum is a curiosity-inducing place to see in Metsovo. Then, wander over to Museum Of The Royal Tombs At Aigai (aegae). If photogenic sites excite you, this museum will be right up your alley. Nearby, you’ll also find Haliacmon Dam - Artificial Lake At Saint Barbara Of Veria. This eye-catching lake is a favorite among visitors.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Thessaloniki. Thessaloniki offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Thessaloniki's best restaurants.

Enjoy a delicious meal at Enoches Bar, a highly-rated dining destination in Thessaloniki. If you're eager to try something different, consider O Loytros, another top spot with a tantalizing menu. You might also want to secure a reservation at rOOTS. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Thessaloniki this evening.

If you’re not ready to end the night just yet, Peiratis Cafe-bar offers a perfect venue to relax and savor a drink. Similarly, In Rock Cafe Bar is well-suited for those looking to unwind in a social setting. Tribeca is another excellent spot to enjoy a nightcap after a delightful meal.

Raise your glass to another unforgettable day in Greece!

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Day 7

Day 7

  • Thessaloniki - Departure day
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  • Arch of Galerius
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Day 7 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Arch Of Galerius And Rotunda. This well-known monument is a hotspot among locals.

Make the most of your final day in Greece by visiting Thessaloniki’s iconic markets and shopping establishments in the buzzing Modiano Market. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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