7-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki to Kavala Prefecture, Xanthi, Serres, and Larissa and surrounding area

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Experience the freedom of the open road in Greece as you embark on an unforgettable 7-day road trip! This experience caters to every traveler, featuring destinations like Thessaloniki, Kavala Prefecture, Alexandroupoli, Xanthi, Krinides, Lydia, Aggitis, Serres, Vergina, Katerini, Larissa, Makrinitsa, Portaria, and Volos.

This perfectly planned road trip itinerary in Greece takes you through some of the best places to see in the country. You will spend 2 nights in Thessaloniki, 1 night in Kavala Prefecture, 1 night in Xanthi, 1 night in Serres, and 1 night in Larissa. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable The Umbrellas Sculpture By Zogolopoulos, learn more about the unique Arch Of Galerius And Rotunda, and immerse yourself in the vibrant atmosphere of Agias Sofias Square.

As you hit the open road and drive through Thessaloniki, Kavala Prefecture, Alexandroupoli, Xanthi, Krinides, Lydia, Aggitis, Serres, Vergina, Katerini, Larissa, Makrinitsa, Portaria, and Volos, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Ladadika
Aristotelous SquareAgias Sofias SquareWhite Tower of ThessalonikiThe Umbrellas by Zongolopoulos
Kavala FortFaliro ParkLighthouse of AlexandroupoliThe House of ShadowDimokratias Square
Ancient theatre of PhilippiArchaeological Museum of PhilippiHoly Baptistery of Saint Lydia of PhilippiCave Aggitis River
Liberty SquarePolycentric Museum of Aigai (Aegae) - Main BuildingMuseum of the Royal Tombs at Aigai (Aegae)Katerini Municipal Park
Makrinitsa Central SquareCentaurs' pathSaint Konstantinos ParkΠαραλία Βόλου
Arch of Galerius

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Day 1

Day 1

  • Thessaloniki - Arrival day
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  • Ladadika
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Welcome to Thessaloniki, the perfect starting point for your road trip in Greece! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Thessaloniki's charm before embarking on the next leg of your journey.

Thessaloniki is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ladadika, a must-see neighborhood, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Thessaloniki. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at Kitchen Bar, a popular restaurant in Thessaloniki. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Thessaloniki at The Greek, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Phanós. It’s yet another ideal choice to enhance your time in Thessaloniki tonight.

Extend your evening after a delightful meal by visiting Beetle Bar, which offers the perfect atmosphere for a night out. Moreover, Vogatsikou 3 is another popular option for a drink or two. Likewise, Souel also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Raise a toast to the start of your 7-day road trip in Greece!

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Day 2

Day 2

  • Thessaloniki
  • Kavala
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Drive 161 km, 2 hours 30 min

  • Aristotelous Square
  • Agias Sofias Square
  • White Tower of Thessaloniki
  • The Umbrellas by Zongolopoulos
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Dive into day 2 of your remarkable road trip in Greece. Today you will explore Thessaloniki, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Kavala Prefecture. You’ll stay here for 1 night.

Discover a day packed with family-friendly attractions, romantic experiences, and breathtaking views in Thessaloniki. Begin your sightseeing with Aristotelous Square. This captivating public square is one of the top attractions in the city. Proceed to Agias Sofias Square, another must-visit attraction.

As you wander through the inviting streets of Thessaloniki, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to White Tower Of Thessaloniki. This famous monument is a traveler-favorite. Not far away, you’ll find The Umbrellas Sculpture By Zogolopoulos, another key site on your sightseeing itinerary.

When you’re done exploring for the day, you’ll drive to your hotel in Kavala Prefecture. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of Kavala Prefecture's most popular restaurants, and connect with friendly locals for an authentic adventure.

Have a fantastic dining experience at Meltemi, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Tsalapeteinos (Tsalapeteinos Urban Farm) offers an enticing alternative with its varied menu. Additionally, Marine Cafe Bar Restaurant is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Kavala Prefecture.

Keep the evening going at Sofita, a great choice for enjoying the after-dinner hours with a drink. You could also go to Beyond Cafe-bar, which offers a similarly pleasant setting and great drinks. Another option is Brickwall Pub, which provides an inviting environment for unwinding after a busy day out.

Savor another day of unforgettable experiences in Greece!

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Day 3

Day 3

  • Kavala
  • Xanthi
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Drive 254 km, 3 hours 23 min

  • Kavala Fort
  • Faliro Park
  • Lighthouse of Alexandroupoli
  • The House of Shadow
  • Dimokratias Square
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Experience an unparalleled adventure on day 3 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 3 vibrant destinations - Kavala Prefecture, Alexandroupoli, and Xanthi. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Xanthi. You will spend 1 night here for some well-deserved relaxation.

Start your adventure at Kavala Fortress. This up-and-coming castle is a must-visit for travelers looking for a unique holiday experience. Make your way to Faliro Park located in Kavala Prefecture for another exciting encounter.

Next, immerse yourself in the setting of Lighthouse Of Alexandroupoli. Its romantic features will captivate you. After the lighthouse, continue your tour of the city with a visit to The House Of Shadow. Visitors usually appreciate the photogenic features of this art installation. Next up is Republic Square, a highly recommended public square.

At the end of the day, you will drive to Xanthi, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Xanthi. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a wonderful meal at Fanarakia, a top-rated dining spot in Xanthi. If you're in the mood for something new, try KooKooVaya Urban Gastronomy, another premier location with a delectable menu. You might also want to book a table at Amalthia. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Xanthi.

Extend your evening after a delightful meal by visiting Βaiser Cafe-bar, which offers the perfect atmosphere for a night out. Moreover, Mikro Cafe is another popular option for a drink or two. Likewise, Nostos also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Say good night to Xanthi and look forward to another great day of your road trip in Greece!

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Day 4

Day 4

  • Xanthi
  • Serres Regional Unit
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Drive 194 km, 3 hours 15 min

  • Ancient theatre of Philippi
  • Archaeological Museum of Philippi
  • Holy Baptistery of Saint Lydia of Philippi
  • Cave Aggitis River
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On day 4 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 3 destinations, Krinides, Lydia, and Aggitis. When you’re not sightseeing, take time to relax at your selected hotel in Serres, where you’ll be staying for 1 night.

Today’s route brings fun adventures, scenic views, and picturesque spots. The first attraction of today is Ancient Theatre Of Philippi. This up-and-coming archeological site is an awe-inspiring place to see in Xanthi. Continue your discovery at Archaeological Museum Of Philippi, an UNESCO world heritage-listed museum with stories to tell.

As you stroll around Xanthi, take in the distinct atmosphere and learn what makes this town so unique. Maximize your sightseeing with a visit to Holy Baptistery Of Saint Lydia Of Philippi. This beloved church offers an awe-inspiring encounter with Xanthi. Next, make your way to Aggitis River Cave to add another highlight to your day. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Xanthi.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Serres. Serres offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat in Serres. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Oyzadikon To Bakalikon, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try KENTRIKON Ouzomezedopoleio? It's another excellent option with a diverse menu. Consider reserving a table at Sousouráda as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Serres.

To truly maximize your evening out, consider visiting Avissunia Kafe after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Resalto Pub, another bar with an inviting ambiance. Similarly, 1800 Cafe Bar also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Raise your glass and celebrate another amazing day of your road trip in Greece!

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Day 5

Day 5

  • Serres Regional Unit
  • Larissa
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Drive 277 km, 3 hours 49 min

  • Liberty Square
  • Polycentric Museum of Aigai (Aegae) - Main Building
  • Museum of the Royal Tombs at Aigai (Aegae)
  • Katerini Municipal Park
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Embark on another extraordinary experience on day 5 of your road trip in Greece. Today, you will make 3 stops and experience some of the highlights of Serres, Vergina, and Katerini. At the end of the day, you will enjoy the comforts of a top-rated hotel in Larissa, which will be your home away from home for 1 night.

Start by visiting Liberty Square, a prime spot to begin your journey. This eye-catching public square is sure to impress. Next on your list is Polycentric Museum Of Aigai (aegae) - Main Building, another must-visit landmark and underrated museum renowned for its respected features.

While exploring and sightseeing, take time to savor the culture of Serres by sampling some local delicacies. When you’re ready for more sightseeing, head to Museum Of The Royal Tombs At Aigai (aegae). This photogenic museum is an essential place to visit for anyone looking for the full Serres experience. We also recommend visiting Katerini Municipal Park, a worthwhile park.

When you’re done exploring for the day, you’ll drive to your hotel in Larissa. Check in and spend some time relaxing before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Larissa. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Don’t miss out on dining at Nonna Rossa, a top-rated dining destination in Larissa. If you're in the mood to try something new, consider Vosporos | Restaurant • Bar, another top spot with a mouthwatering menu. You might also want to secure a reservation at THE ALLEY. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Larissa this evening.

Continue your evening by exploring the vibrant nightlife scene at Sherlock Easy Bar, a prime destination for a thrilling night out. Also, don’t forget to check out Kiou, a bar that offers unique local touches. Likewise, Wisedog provides an excellent alternative for a fun evening.

Relax and recharge in preparation for another adventurous day in Greece!

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Day 6

Day 6

  • Larissa
  • Thessaloniki
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Drive 294 km, 4 hours 15 min

  • Makrinitsa Central Square
  • Centaurs' path
  • Saint Konstantinos Park
  • Παραλία Βόλου
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On day 6 of your road trip in Greece, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Makrinitsa, Portaria, and Volos. In the evening, you’ll end up in Thessaloniki, where you will stay for 1 night.

Today’s itinerary in Larissa covers several incredible sights, including a public square, a hiking area, a park, a beach and much more! Start your adventure at Makrinitsa. This frequently visited public square is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the mesmerizing wonders of Centaurs' Path, a must-see hiking area in the village.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Saint Konstantinos Park. This increasingly popular park offers an enriching experience. For a change of pace, head to Paralia Voloy, where you can take in serene features. These sights offer a fulfilling end to a perfect day.

At the end of the day, you will drive to Thessaloniki, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Thessaloniki, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Make sure to reserve a table at Mamalouka, an iconic dining spot in Thessaloniki. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Clochard, a popular restaurant in Thessaloniki. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Sofi's House Restaurant, a hidden gem nestled in Thessaloniki. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue your lively evening at Castra- All Day Terrace Bar, a perfect place for winding down or revving up the night, depending on which mood you’re in. Barbaben - Bar/ba/ben is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Apallou ensures a night out tailored to your taste.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Greece.

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Day 7

Day 7

  • Thessaloniki - Departure day
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  • Arch of Galerius
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Day 7 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Arch Of Galerius And Rotunda, an instagrammable monument before you head out.

Maximize your last day in Greece and go on a shopping spree in Thessaloniki’s shopping center, the lively Modiano Market. Browse for souvenirs to remind you of your wonderful journey in Greece.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

Savor the flavors at Enoches Bar, a top pick for dinner tonight. Alternatively, O Loytros beckons with its unique menu offerings.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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