7-Day Greece Self-Drive Road Trip With Itinerary from Thessaloniki traveling west to Veria, Ioannina, and Trikala

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Photo of Saint Paul cathedral in Thessaloniki, Greece.
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Explore the best of Greece on a remarkable 7-day road trip! Combine exploration with relaxation on a self-drive tour featuring Thessaloniki, Edessa, Veria, Metsovo, Mandio, Ioannina, Perama, Neo Bizani, Trikala, and Kastraki.

This perfectly planned road trip itinerary takes you through some of the best places to see in Greece. You will spend 3 nights in Thessaloniki, 1 night in Veria, 1 night in Ioannina, and 1 night in Trikala. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Greece. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Thessaloniki, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Greece on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Greece. White Tower Of Thessaloniki and Aristotelous Square are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Meteora, learn more about the unique Waterfalls Park, Edessa, and immerse yourself in the vibrant atmosphere of The Umbrellas Sculpture By Zogolopoulos.

As you hit the open road and drive through Thessaloniki, Edessa, Veria, Metsovo, Mandio, Ioannina, Perama, Neo Bizani, Trikala, and Kastraki, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Greece. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Greece.

Throughout your road trip in Greece, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Greece.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Greece fill up quickly, so book your spot early. Select a date and start planning your road trip in Greece today!

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Driver’s age is 30 - 65
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Day 1

Day 1

  • Thessaloniki - Arrival day
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  • Ladadika
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Say hello to Thessaloniki! Your exciting road trip through Greece is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Thessaloniki for 2 nights before you continue your adventure!

Thessaloniki is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Ladadika, a must-see neighborhood, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Thessaloniki. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Thessaloniki, it's often a good idea to reserve a table in advance.

Treat yourself to a delicious dinner at Kitchen Bar, an excellent option for tonight's dining. Looking for something different? The Greek offers a tantalizing alternative with its diverse menu. And don’t miss Phanós. Known for great service, it’s a fantastic choice for tonight in Thessaloniki.

To truly maximize your evening out, consider visiting Beetle Bar after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Vogatsikou 3, another bar with an inviting ambiance. Similarly, Souel also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Raise a toast to the start of your 7-day road trip in Greece!

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Day 2

Day 2

  • Thessaloniki
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Drive 6 km, 55 min

  • The Umbrellas by Zongolopoulos
  • Archaeological Museum of Thessaloniki
  • White Tower of Thessaloniki
  • Aristotelous Square
  • Tsimiski Street
  • More

On day 2 of your road trip, you will have an entire day to discover what to see in Thessaloniki. You’ll stay in Thessaloniki for 1 night.

Don’t miss Tsimiski Street today, a must-see street that offers a glimpse into the city’s vibrant character. Take your time to explore its best features, and enjoy the convenience of nearby top-rated landmarks.

To truly experience Thessaloniki, make sure to drop by The Umbrellas Sculpture By Zogolopoulos. This captivating art installation is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Archaeological Museum Of Thessaloniki, one of the city’s best highlights.

Next, check out White Tower Of Thessaloniki, one of the most famous places to see in Thessaloniki. This monument is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Aristotelous Square. Wander around and soak in the history-steeped atmosphere this public square offers.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Greece. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Thessaloniki's most popular restaurants, and connect with friendly locals for a true cultural experience.

Make sure to reserve a table at Mamalouka, an iconic dining spot in Thessaloniki. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Clochard, a popular restaurant in Thessaloniki. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Sofi's House Restaurant, a hidden gem nestled in Thessaloniki. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Extend your evening after a delightful meal by visiting Castra- All Day Terrace Bar, which offers the perfect atmosphere for a night out. Moreover, Barbaben - Bar/ba/ben is another popular option for a drink or two. Likewise, Apallou also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Raise your glass to another unforgettable day in Greece!

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Day 3

Day 3

  • Thessaloniki
  • Veroia
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Drive 131 km, 2 hours 50 min

  • Kapani
  • Church of St Demetrios
  • Atatürk Museum
  • Arch of Galerius
  • Edessa Waterfalls
  • More

On day 3 of your exciting self-drive vacation in Greece, you’ll soak in the magnificence of 2 destinations, including Thessaloniki and Edessa. When you’re not sightseeing, take time to relax at your chosen hotel in Veria, where you’ll be staying for 1 night.

Kapani leaves a lasting impression. This market is one of the most popular places to visit in Thessaloniki. Next, head to Holy Church Of Saint Demetrius, Patron Saint Of Thessalonica, an increasingly popular church, known for its culturally significant features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Atatürk Museum. This respected museum is a highly recommended experience. Nearby, you'll also find Arch Of Galerius And Rotunda and Waterfalls Park, Edessa. Visit these for an interesting touch to your journey.

At the end of the day, you will drive to Veria, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Veria. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely dining experience at Plátanos, a popular restaurant in Veria. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Veria at Psaropoúla, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Stasoy Mygdala. It’s yet another ideal choice to enhance your time in Veria tonight.

Explore the vibrant nightlife at Kochlías after your meal, a hub for lively evenings and memorable moments. Or, head to Floretta Cafe Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Delante Bar is perfect for those looking to extend their night with a touch of local flavor.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Greece.

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Day 4

Day 4

  • Veroia
  • Ioannina
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Drive 246 km, 3 hours 37 min

  • Anilio Ski Center
  • Αβερώφειος Κήπος
  • Metsovo square
  • Averoff Art Gallery
  • Archaeological Site of Dodoni
  • More

On day 4 of your road trip in Greece, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Metsovo and Mandio are on today's agenda. In the evening, you’ll end up in Ioannina, where you will stay for 1 night.

Let Anilio Ski Center set the tone for the day. Spend some time admiring this picturesque ski resort before continuing your journey. Averofeios Kipos is your next stop. This locally appreciated park is one of the best-rated sights in Veria.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Metsovo Square. This romantic public square is a sight to behold. To round off your sightseeing experience, visit Averoff Art Gallery and Archaeological Site Of Dodoni.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Ioannina. Ioannina offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Ioannina is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Ioannina.

Enjoy a delicious meal at To Dodeka Cafe Bar, a top-rated dining destination in Ioannina. If you're in the mood to try something new, consider Mustagogia, another top spot with a mouthwatering menu. You might also want to secure a reservation at Accademia Del Panino. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Ioannina this evening.

Continue your lively evening at ⚜ V E D E M A ⚜, a perfect place for winding down or revving up the night, depending on which mood you’re in. Hogwarts Tales And Spirits is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Chevalier ensures a night out tailored to your taste.

Say good night to Ioannina and look forward to another great day of your road trip in Greece!

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Day 5

Day 5

  • Ioannina
  • Trikala
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Drive 153 km, 3 hours 1 min

  • The Clock Tower of Ioannina
  • Ioannina Castle
  • Ich Kale Acropolis of Ioannina
  • Cave of Perama
  • Vrellis Greek History Museum (Wax Museum)
  • More

Experience an unparalleled adventure on day 5 of your road trip in Greece. This exciting part of your journey invites you to discover the renowned landmarks in 3 places, which are Ioannina, Perama, and Neo Bizani. At the end of the day, you will retreat to the hotel of your choice in Trikala, where will spend 1 night.

Visiting The Clock Tower Of Ioannina is always a good idea. This increasingly popular monument is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the grand wonders of Ioannina Castle, a must-see castle in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Ic Kale Acropolis Of Ioannina. This beloved archeological site offers an enriching experience. For a change of pace, head to Cave Of Perama, where you can take in peaceful features. Conclude your self-guided sightseeing tour with a visit to Moyseio Ellinikis Istorias Payloy Vrelli. These sights offer a fulfilling end to a perfect day.

When you’re done exploring for the day, you’ll drive to your hotel in Trikala. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Trikala. Enjoy a relaxing evening as you savor delicious local cuisine.

Make sure to reserve a table at ALVEO, an iconic dining spot in Trikala. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Trikala Fortress, a popular restaurant in Trikala. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Palia Istoria, a hidden gem nestled in Trikala. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue the enjoyment post-dinner at Soyita Art Cafe, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Factory Café offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out The Love Shake. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Head back to your accommodation in Trikala and get some rest to prepare for another magical day of your road trip in Greece.

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Day 6

Day 6

  • Trikala
  • Thessaloniki
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Drive 257 km, 4 hours 16 min

  • Trikala City Center Square
  • Matsopoulos Park
  • The Great Meteoron Holy Monastery of the Transfiguration of the Saviour
  • Meteora
  • More

Dive into day 6 of your remarkable road trip in Greece. Today you'll explore 2 destinations, including Trikala and Kastraki. At the end of the day, you’ll unwind at one of the finest accommodations in Thessaloniki, where you'll spend 1 night.

One of the most increasingly popular attractions included on the itinerary is Trikala City Center Square. This eye-catching public square will help you start your sightseeing on top. Then, take a leisurely stroll to Matsopoulos Park and learn what makes this enchanting park unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the up-and-coming Holy Monastery Of The Great Meteoron -transfiguration Of The Saviour. After exploring the monastery, head to Meteora. This interesting monastery is a highlight in Trikala.

At the end of the day, you will drive to Thessaloniki, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Thessaloniki's most popular restaurants, and connect with friendly locals for a true cultural experience.

Savor the flavors at Enoches Bar, a top pick for dinner tonight. Alternatively, O Loytros beckons with its unique menu offerings. Also, consider rOOTS. With its consistent customer satisfaction, it’s an excellent option for dining in Thessaloniki tonight.

After your meal, keep the night alive at a bar like Peiratis Cafe-bar, known for its lively atmosphere. In Rock Cafe Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Tribeca offers an excellent atmosphere for those looking to amp up the evening.

Raise your glass and celebrate another amazing day of your road trip in Greece!

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Day 7

Day 7

  • Thessaloniki - Departure day
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  • Agias Sofias Square
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Day 7 of your road trip in Greece is your departure day. This is your chance to catch a last glimpse of Thessaloniki before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Agias Sofias Square, a symbolic public square before you head out.

For a shopping spree in Thessaloniki, we recommend the lively Modiano Market. Here, you'll find a range of shops you can browse for some souvenir shopping.

Before you conclude your road trip in Greece, drop by another restaurant for a last chance at a memorable dining experience in Thessaloniki.

You’ll then say farewell to Thessaloniki. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Greece!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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