Introduction
Unlock the best places to stay in Mytilene with these top 10 picks! Whether you’re seeking proximity to vibrant areas, exceptional amenities, or everything in between, this list covers all you need for a memorable stay in Mytilene.
Choosing where to stay in Mytilene can feel overwhelming with so many options available. That's why we've reviewed the largest selection of hotels in Mytilene and put together a guide to the 10 best places to stay in the city.
The best hotels in Mytilene are near! Keep reading to uncover the latest list of the top places to stay in the city.
Top 5 Best Neighborhoods To Stay in Mytilene
Choosing the best neighborhoods to stay in Mytilene is key to making the most of your visit. The right location can give you easy access to top sights, great local food, and the unique charm of this Greek island city. Here are the top five neighborhoods to consider, ranked from good to best, to help you decide where to book your stay.
5. Epano Skala - Historic and Local
Epano Skala is the best neighborhood to stay in Mytilene if you want a local vibe and affordable guesthouses. This area features the historic Yeni Mosque and the old market, offering a glimpse into the city's multicultural past. It’s a quieter part of town but still within walking distance to the waterfront.4. Tsamakia Beach - Relaxed and Scenic
Tsamakia Beach is the best neighborhood to stay in Mytilene for travelers who want easy beach access and sea views. The area has several mid-range hotels and is ideal for families or couples seeking a quiet, scenic spot. The sandy beach is perfect for swimming, and you’re still close to the city center.3. Sourada - Elegant and Residential
Sourada is the best neighborhood to stay in Mytilene if you prefer a peaceful, upscale environment. Known for its neoclassical mansions, this area offers boutique hotels and stylish guesthouses. It’s a great choice for those interested in architecture and a more refined atmosphere, with easy transport links to the old town.2. Varia - Artistic and Authentic
Varia is the best neighborhood to stay in Mytilene for art lovers and culture seekers. Home to the famous Theophilos Museum and close to the Teriade Museum, Varia has a relaxed feel and affordable accommodations. It’s ideal if you want to explore local culture while staying in a quieter residential area.1. Mytilene Old Town - Central and Lively
Mytilene Old Town is the best neighborhood to stay in Mytilene for first-time visitors who want to be in the heart of the action. Here, you'll find the impressive Mytilene Castle, plenty of cafes, shops, and a range of hotels from budget to boutique. Its central location makes it easy to explore all major attractions on foot.Explore Mytilene Stays
Choose your Mytilene stay style here. Browse by category to find your next stay in Mytilene.
Search for Places To Stay in Mytilene
Browse the largest selection of hotels and accommodations in Mytilene, all backed by a best-price guarantee. Whether you’re looking for a central location, pet-friendly options, or a place with a pool, simply enter your travel dates to find your perfect stay in Mytilene.
The 10 Best Places To Stay in Mytilene
Discover our updated list of the top 10 best places to stay in Mytilene, chosen for their exceptional comfort, top-rated service, and prime locations. From luxurious retreats to budget-friendly spots, there’s a hotel for every traveler.
Find your perfect base below and make your Mytilene adventure truly unforgettable!
10. Mirsini
- Comfort Level: 2-star hotel
- Guest Rating: 4.6 out of 5 stars from 236 reviews
- Location: Just 12.6 miles (20.3 km) from the city center
- Nearest Attractions: Παναγία της Αγιάσου and Castle of Mytilene
- Check-in: 12:00 PM
- Check-out: 12:00 PM
- Starting Rate: 78 EUR
Located just 12.6 miles (20.3 km) from the city center, Mirsini provides easy access to iconic landmarks like the remarkable Παναγία της Αγιάσου and Castle of Mytilene.
But that's just the beginning of what makes this hotel stand out. At Mirsini, guests can expect a seamless and comfortable stay with amenities like room service, 24-hour front desk, garden, terrace, family rooms, free Wi-Fi, and air conditioning. Room prices at Mirsini start from 78 EUR.
Thanks to its exemplary service, Mirsini has become known for its exceptional hospitality and guest satisfaction. This, along with a combination of clean and well-designed accommodations, perfect location, and value for money, makes Mirsini one of the top choices when considering where to stay in Mytilene.
9. Zaira Hotel
- Comfort Level: 4-star hotel
- Guest Rating: 4.6 out of 5 stars from 315 reviews
- Location: Just 4.2 miles (6.7 km) from the city center
- Distance from Mytilene International Airport: 3.9 miles (6.2 km)
- Nearest Attractions: Castle of Mytilene and Παναγία της Αγιάσου
- Check-in: 3:00 PM
- Check-out: 11:00 AM
- Starting Rate: 139 EUR
Zaira Hotel is just 4.2 miles (6.7 km) from the city center. You’ll find it conveniently close to attractions like Castle of Mytilene and Παναγία της Αγιάσου.
In addition, the hotel offers convenient amenities, including garden, restaurant, room service, bar, family rooms, hot tub, free Wi-Fi, air conditioning, and swimming pool.
Room rates at Zaira Hotel start at 139 EUR. Overall, Zaira Hotel provides a comfortable and convenient stay, making it one of the best hotel options in Mytilene.
8. Sappho Studios
- Guest Rating: 4.6 out of 5 stars from 326 reviews
- Location: Just 2 miles (3.2 km) from the city center
- Distance from Mytilene International Airport: 2.3 miles (3.7 km)
- Nearest Attractions: Castle of Mytilene and Παναγία της Αγιάσου
- Check-in: 1:00 PM
- Check-out: 11:00 AM
- Starting Rate: 92 EUR
This vacation rental apartment places you just 2 miles (3.2 km) from the city center. Nearby attractions include Castle of Mytilene and Παναγία της Αγιάσου.
Amenities at Sappho Studios include air conditioning, garden, family rooms, terrace, and free Wi-Fi. Room rates start at 92 EUR.
Recognized among the top 10 best places to stay in Mytilene, Sappho Studios ensures a memorable and comfortable experience for all guests.
7. Oikies Small Elegant Houses
- Comfort Level: 3-star hotel
- Guest Rating: 4.4 out of 5 stars from 435 reviews
- Location: Just 3 miles (4.8 km) from the city center
- Distance from Mytilene International Airport: 1.6 miles (2.5 km)
- Nearest Attractions: Castle of Mytilene and Παναγία της Αγιάσου
- Check-in: 2:00 PM
- Check-out: 12:00 PM
- Starting Rate: 117 EUR
Conveniently located just 3 miles (4.8 km) from the city center, this hotel provides easy access to attractions like Castle of Mytilene and Παναγία της Αγιάσου.
Guests appreciate Oikies Small Elegant Houses for its excellent and functional amenities, including air conditioning, 24-hour front desk, room service, bar, restaurant, free Wi-Fi, airport shuttle, swimming pool, garden, and family rooms. The hotel also boasts a warm ambiance and guest-centered service.
At Oikies Small Elegant Houses, rooms are well-designed and priced from 117 EUR. Guests can look forward to a comfortable stay that enhances their overall experience in Mytilene.
6. Elysion Hotel
- Comfort Level: 5-star hotel
- Guest Rating: 4.4 out of 5 stars from 446 reviews
- Location: Just 3.4 miles (5.5 km) from the city center
- Distance from Mytilene International Airport: 0.9 miles (1.5 km)
- Nearest Attractions: Castle of Mytilene and Παναγία της Αγιάσου
- Check-in: 3:00 PM
- Check-out: 11:00 AM
- Starting Rate: 181 EUR
The hotel is situated 3.4 miles (5.5 km) from the city center. Its perfect location places it near notable attractions like Castle of Mytilene and Παναγία της Αγιάσου, ensuring easy access to these points of interest.
Elysion Hotel features essential and functional amenities, including air conditioning, garden, terrace, room service, family rooms, bar, restaurant, airport shuttle, swimming pool, and 24-hour front desk. Room rates at this hotel start at 181 EUR.
With its blend of comfort, style, and prime location, Elysion Hotel stands out as a top choice among travelers to Mytilene. Its thoughtful amenities and proximity to top attractions in the city make it a standout option for your visit.
5. Heliotrope The Studios
- Guest Rating: 4.4 out of 5 stars from 573 reviews
- Location: Just 0.3 miles (0.4 km) from the city center
- Distance from Mytilene International Airport: 5 miles (8 km)
- Nearest Attractions: Castle of Mytilene and Παναγία της Αγιάσου
- Check-in: 3:00 PM
- Check-out: 11:00 AM
- Starting Rate: 68 EUR
At the vacation rental apartment, guests can enjoy amenities such as air conditioning, garden, terrace, room service, family rooms, and free Wi-Fi.
Heliotrope The Studios benefits from a perfect location and is situated 0.3 miles (0.4 km) from the city center. Nearby attractions like Castle of Mytilene and Παναγία της Αγιάσου are easily accessible.
Offering excellent value for money, room rates start at 68 EUR for the cheapest options. Guests can expect both comfort and quality, no matter which option they choose.
4. Elies Residences
- Guest Rating: 4.8 out of 5 stars from 213 reviews
- Location: Just 3.1 miles (5 km) from the city center
- Distance from Mytilene International Airport: 1.3 miles (2.2 km)
- Nearest Attractions: Castle of Mytilene and Παναγία της Αγιάσου
- Check-in: 3:00 PM
- Check-out: 12:00 PM
- Starting Rate: 136 EUR
Guests at Elies Residences benefit from a range of amenities, including garden, terrace, family rooms, free Wi-Fi, air conditioning, and swimming pool. It offers value for money, with room rates starting from 136 EUR.
The vacation rental apartment provides various activities, such as hiking and water sports facilities.
Elies Residences has a convenient and perfect location, just 3.1 miles (5 km) from the city center. It provides easy access to landmarks such as Castle of Mytilene and Παναγία της Αγιάσου.
Located near prominent attractions, Elies Residences offers a refined stay experience in Mytilene. Its commitment to comfort and quality service ensures that guests have a pleasant and relaxing visit.
3. Theofilos Paradise Boutique Hotel
- Comfort Level: 4-star hotel
- Guest Rating: 4.6 out of 5 stars from 538 reviews
- Location: Just 0.3 miles (0.5 km) from the city center
- Distance from Mytilene International Airport: 4.3 miles (6.8 km)
- Nearest Attractions: Castle of Mytilene and Παναγία της Αγιάσου
- Check-in: 2:00 PM
- Check-out: 11:00 AM
- Starting Rate: 101 EUR
This renowned hotel boasts convenient and functional amenities, including air conditioning, 24-hour front desk, garden, terrace, room service, bar, restaurant, airport shuttle, swimming pool, sauna, free Wi-Fi, family rooms, and spa.
The hotel's perfect location, just 0.3 miles (0.5 km) from Mytilene's dynamic center, allows easy access to standout attractions such as the top-rated Castle of Mytilene and the captivating Παναγία της Αγιάσου.
Beyond its stylish and well-designed accommodations, Theofilos Paradise Boutique Hotel captivates with its prompt and exemplary service. Overall, staying one night or two at Theofilos Paradise Boutique Hotel during a trip to Mytilene offers a memorable experience and excellent value.
With Theofilos Paradise Boutique Hotel, guests step into a world of extraordinary service and indulgent comfort. Room rates start from 101 EUR, making Theofilos Paradise Boutique Hotel a standout choice for those deciding where to stay in Mytilene.
2. Loriet Hotel
- Guest Rating: 4.3 out of 5 stars from 1617 reviews
- Location: Just 1.9 miles (3.1 km) from the city center
- Distance from Mytilene International Airport: 2.4 miles (3.9 km)
- Nearest Attractions: Castle of Mytilene and Παναγία της Αγιάσου
- Check-in: 3:00 PM
- Check-out: 11:00 AM
- Starting Rate: 132 EUR
Conveniently located just 1.9 miles (3.1 km) from the city center, Loriet Hotel makes it easy to visit popular attractions like Castle of Mytilene and Παναγία της Αγιάσου.
The vacation rental apartment is highly regarded for its functional amenities, including air conditioning, garden, terrace, room service, family rooms, bar, restaurant, airport shuttle, swimming pool, and free Wi-Fi.
During your stay, enjoy fishing, water sports facilities, and diving, further enhancing your time in Mytilene. Entertainment options such as board games ensure something for everyone.
Room rates at Loriet Hotel start from 132 EUR. Overall, this property offers good value for money, making it suitable for travelers seeking a great experience.
1. Porto Lesvos
- Comfort Level: 2-star hotel
- Guest Rating: 4.4 out of 5 stars from 1155 reviews
- Location: Just 0.3 miles (0.5 km) from the city center
- Distance from Mytilene International Airport: 4.4 miles (7 km)
- Nearest Attractions: Castle of Mytilene and Παναγία της Αγιάσου
- Check-in: 7:30 AM
- Check-out: 11:00 AM
- Starting Rate: 44 EUR
With its superior amenities, welcoming ambiance, and elegant rooms, Porto Lesvos is undeniably the number one place to stay in Mytilene. This 2-star hotel is renowned for its exceptional service and sets the highest standard for hospitality.
Situated just 0.3 miles (0.5 km) from the lively city center, Porto Lesvos's perfect location offers easy access to Mytilene's top attractions, including Castle of Mytilene and Παναγία της Αγιάσου.
Guests appreciate the top-notch amenities, including air conditioning, 24-hour front desk, room service, restaurant, and free Wi-Fi.
With room rates starting from 44 EUR, Porto Lesvos offers exceptional value. Guests seeking where to stay in Mytilene, Greece, will find Porto Lesvos delivers an experience that’s second to none.
What To Discover Next in Mytilene
Finding the perfect place to stay in Mytilene is just the beginning of your adventure.
Your time in Mytilene should be spent enjoying the sights, not worrying about logistics. Use the links below and our comprehensive travel guide about Mytilene to simplify your travel plans.
