Top 10 Places To Stay in Mytilene

Discovering the best neighborhoods to stay in Mytilene is key to enhancing your travel experience. Each area offers unique attractions and characteristics, ensuring that your visit to this vibrant city on the island of Lesbos is unforgettable.

5. Vareia - Cultural and Quaint

4. Kalamiaris - Scenic and Serene

3. Epano Skala - Historical and Close to Town

2. Kioski - Vibrant and Convenient

1. Mytilene Town Center - Central and Lively

With a diverse range of hotels and accommodations available in Mytilene, there's something to suit every traveler's preferences. Use the categories below to navigate all options and find your next stay in Mytilene.

Browse the largest selection of hotels and accommodations in Mytilene, all backed by a best-price guarantee. Whether you’re looking for a central location, pet-friendly options, or a place with a pool, simply enter your travel dates to find your perfect stay in Mytilene.

Discover our updated list of the top 10 best places to stay in Mytilene, chosen for their exceptional comfort, top-rated service, and prime locations. From luxurious retreats to budget-friendly spots, there’s a hotel for every traveler.

Find your perfect base below and make your Mytilene adventure truly unforgettable!

• Comfort Level: 3-star hotel
• Guest Rating: 4 out of 5 stars from 1240 reviews
• Location: Just 0.3 miles (0.5 km) from the city center
• Distance from Mytilene International Airport: 4.2 miles (6.7 km)
• Nearest Attractions: Castle of Mytilene and Παναγία της Αγιάσου
• Check-in: 1:00 PM
• Check-out: 11:30 AM
• Starting Rate: 71 EUR

Located just 0.3 miles (0.5 km) from the city center, Hotel Blue Sea provides easy access to iconic landmarks like the remarkable Castle of Mytilene and Παναγία της Αγιάσου.

Guests of this hotel can enjoy entertainment options like pub crawls, ensuring plenty to do during their stay.

But that's just the beginning of what makes this hotel stand out. At Hotel Blue Sea, guests can expect a seamless and comfortable stay with functional amenities like restaurant, bar, spa, free Wi-Fi, room service, air conditioning, family rooms, terrace, and 24-hour front desk. Room prices in Hotel Blue Sea begin at 71 EUR and extend up to 71 EUR, providing options that cater to a variety of budgets.

Thanks to its exemplary service, Hotel Blue Sea has become known for its exceptional hospitality and guest satisfaction. This, along with a combination of clean and well-designed accommodations, perfect location, and value for money, makes Hotel Blue Sea one of the top choices for travelers seeking an unforgettable stay in Mytilene.

• Guest Rating: 4.8 out of 5 stars from 107 reviews
• Location: Just 0.1 miles (0.2 km) from the city center
• Nearest Attractions: Castle of Mytilene and Παναγία της Αγιάσου
• Check-in: 1:00 PM
• Check-out: 11:00 AM
• Starting Rate: 47 EUR

Guests at Modern House in Mytilene Center benefit from a range of amenities, including family rooms, free Wi-Fi, and air conditioning. It offers value for money, with room rates starting from 47 EUR.

Modern House in Mytilene Center has a convenient location, just 0.1 miles (0.2 km) from the city center. It provides easy access to landmarks such as Castle of Mytilene and Παναγία της Αγιάσου.

Located near prominent attractions, Modern House in Mytilene Center offers a refined stay experience in Mytilene. Its commitment to comfort and quality service ensures that guests have a pleasant and relaxing visit.

• Guest Rating: 4.3 out of 5 stars from 586 reviews
• Location: Just 0.3 miles (0.4 km) from the city center
• Distance from Mytilene International Airport: 5 miles (8 km)
• Nearest Attractions: Castle of Mytilene and Παναγία της Αγιάσου
• Check-in: 3:00 PM
• Check-out: 11:00 AM
• Starting Rate: 55 EUR

This apartment has a perfect location and places you just 0.3 miles (0.4 km) from the city center. Nearby attractions include Castle of Mytilene and Παναγία της Αγιάσου.

Amenities at Heliotrope The Studios include air conditioning, free Wi-Fi, restaurant, room service, garden, and family rooms. Room rates start at 55 EUR.

Recognized among the top 10 best places to stay in Mytilene, Heliotrope The Studios ensures a memorable and comfortable experience for all guests.

• Guest Rating: 4.5 out of 5 stars from 332 reviews
• Location: Just 2 miles (3.2 km) from the city center
• Distance from Mytilene International Airport: 2.3 miles (3.7 km)
• Nearest Attractions: Castle of Mytilene and Παναγία της Αγιάσου
• Check-in: 1:00 PM
• Check-out: 11:00 AM
• Starting Rate: 101 EUR

Conveniently located just 2 miles (3.2 km) from the city center, Sappho Studios makes it easy to visit popular attractions like Castle of Mytilene and Παναγία της Αγιάσου.

The apartment is highly regarded for its amenities, including restaurant, free Wi-Fi, air conditioning, garden, family rooms, terrace, and room service.

Room rates at Sappho Studios start from 101 EUR. Overall, this property offers value for money, making it suitable for travelers seeking a great experience.

• Comfort Level: 4-star hotel
• Guest Rating: 4.4 out of 5 stars from 497 reviews
• Location: Just 0.3 miles (0.5 km) from the city center
• Distance from Mytilene International Airport: 4.3 miles (6.8 km)
• Nearest Attractions: Castle of Mytilene and Παναγία της Αγιάσου
• Check-in: 2:00 PM
• Check-out: 11:00 AM
• Starting Rate: 101 EUR

The hotel is situated 0.3 miles (0.5 km) from the city center. Its perfect location places it near notable attractions like Castle of Mytilene and Παναγία της Αγιάσου, ensuring easy access to these points of interest.

Theofilos Paradise Boutique Hotel features essential and functional amenities, including swimming pool, restaurant, bar, spa, air conditioning, free Wi-Fi, garden, sauna, terrace, room service, airport shuttle, family rooms, and 24-hour front desk. Room rates at this hotel start at 101 EUR.

With its blend of comfort, style, and prime location, Theofilos Paradise Boutique Hotel stands out as a top choice among travelers to Mytilene. Its thoughtful amenities and proximity to top attractions in the city make it a standout option for your visit.

• Comfort Level: 3-star hotel
• Guest Rating: 4.6 out of 5 stars from 380 reviews
• Location: Just 3 miles (4.8 km) from the city center
• Distance from Mytilene International Airport: 1.6 miles (2.5 km)
• Nearest Attractions: Castle of Mytilene and Παναγία της Αγιάσου
• Check-in: 2:00 PM
• Check-out: 12:00 PM
• Starting Rate: 117 EUR

The hotel's perfect location, just 3 miles (4.8 km) from Mytilene's dynamic center, allows easy access to standout attractions such as the top-rated Castle of Mytilene and the captivating Παναγία της Αγιάσου.

Beyond its stylish and well-designed accommodations, Oikies Small Elegant Houses captivates with its prompt and exemplary service. Overall, staying one night or two at Oikies Small Elegant Houses during a trip to Mytilene offers a memorable experience.

With Oikies Small Elegant Houses, guests step into a world of extraordinary service, indulgent comfort, and an unforgettable stay in Mytilene. The starting rates of Oikies Small Elegant Houses's rooms cater to all budgets, which cost from 117 EUR.

• Guest Rating: 4.6 out of 5 stars from 305 reviews
• Location: Just 0.3 miles (0.4 km) from the city center
• Nearest Attractions: Castle of Mytilene and Παναγία της Αγιάσου
• Check-in: 1:00 PM
• Check-out: 11:00 AM
• Starting Rate: 94 EUR

Conveniently located just 0.3 miles (0.4 km) from the city center, ISSA Lesvos provides easy access to attractions like Castle of Mytilene and Παναγία της Αγιάσου.

Guests appreciate ISSA Lesvos for its excellent amenities, including family rooms, free Wi-Fi, and air conditioning. The hostel also boasts a warm ambiance and guest-centered service.

At ISSA Lesvos, rooms are priced from 94 EUR. Guests can look forward to a comfortable stay that enhances their overall experience in Mytilene.

• Guest Rating: 4.8 out of 5 stars from 206 reviews
• Location: Just 2.9 miles (4.7 km) from the city center
• Distance from Mytilene International Airport: 1.3 miles (2.2 km)
• Nearest Attractions: Castle of Mytilene and Παναγία της Αγιάσου
• Check-in: 3:00 PM
• Check-out: 12:00 PM
• Starting Rate: 136 EUR

Moreover, the location is perfect. Elies Residences is just 2.9 miles (4.7 km) from the city center. You’ll find it conveniently close to attractions like Castle of Mytilene and Παναγία της Αγιάσου.

In addition, the apartment offers convenient amenities, including restaurant, free Wi-Fi, air conditioning, garden, family rooms, terrace, and swimming pool.

Or, engage in fun activities like horse-riding, hiking, diving, and yoga classes.

Room rates at Elies Residences start at 136 EUR. Overall, Elies Residences provides a comfortable and convenient stay, making it a top choice for travelers in Mytilene.

• Guest Rating: 4.3 out of 5 stars from 1471 reviews
• Location: Just 1.9 miles (3.1 km) from the city center
• Distance from Mytilene International Airport: 2.4 miles (3.9 km)
• Nearest Attractions: Castle of Mytilene and Παναγία της Αγιάσου
• Check-in: 3:00 PM
• Check-out: 11:00 AM
• Starting Rate: 109 EUR

At the apartment, guests can enjoy amenities such as swimming pool, restaurant, bar, spa, room service, free Wi-Fi, air conditioning, garden, family rooms, terrace, and airport shuttle.

Loriet Hotel benefits from a perfect location and is situated 1.9 miles (3.1 km) from the city center. Nearby attractions like Castle of Mytilene and Παναγία της Αγιάσου are easily accessible.

This remarkable apartment also offers entertainment options like game room and board games and activities such as fishing, bicycle rent, and diving for those seeking an active experience.

Offering good value for money, room rates start at 109 EUR for the cheapest options. Guests can expect both comfort and quality, no matter which option they choose.

• Comfort Level: 2-star hotel
• Guest Rating: 4.4 out of 5 stars from 1167 reviews
• Location: Just 0.3 miles (0.5 km) from the city center
• Distance from Mytilene International Airport: 4.4 miles (7 km)
• Nearest Attractions: Castle of Mytilene and Παναγία της Αγιάσου
• Check-in: 7:30 AM
• Check-out: 11:00 AM
• Starting Rate: 44 EUR

With its superior amenities, welcoming ambiance, and elegant rooms, Porto Lesvos is undeniably the number one place to stay in Mytilene. This 2-star hotel is renowned for its exceptional service and sets the highest standard for hospitality.

Situated just 0.3 miles (0.5 km) from the lively city center, Porto Lesvos's perfect location offers easy access to Mytilene's top attractions, including Castle of Mytilene and Παναγία της Αγιάσου.

Guests appreciate the top-notch amenities, including free Wi-Fi, air conditioning, room service, restaurant, and bar.

With room rates starting from 44 EUR, Porto Lesvos offers exceptional value. A stay here guarantees an unforgettable experience, establishing it as the top choice for Mytilene, Greece.

Deciding where in Mytilene to stay is just the beginning of your adventure. Mytilene is a city rich in history, architectural marvels, and vibrant cultural traditions, offering an immersive experience for every traveler who visits.

Mytilene awaits! Explore the top travel services below for a seamless journey to Mytilene.