10-Day Italy Self-Drive Road Trip With Itinerary from Brindisi to Lecce and Naples

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Escape the ordinary with this exciting 10-day road trip through Italy. Explore the diverse landscapes, lively cities, and beyond. Pack your bags, hit the road, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Brindisi, 3 nights in Lecce, and 4 nights in Naples. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Brindisi, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Amalfi Coast and Piazza Del Plebiscito are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Archaeological Park Of Pompeii, learn more about the unique Sassi Di Matera, and immerse yourself in the vibrant atmosphere of Ovo Castle.

As you hit the open road and drive through Brindisi, Lecce, Castellana Grotte, Alberobello, Matera, Positano, Vico Equense, Naples, Amalfi, Minori, Ravello, Bomerano, Pompei, Ostuni, and Carovigno, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Lungomare Regina Margherita
Porta RudiaeGate of Saint BlaiseCastello Carlo VGiardini Pubblici Giuseppe Garibaldi - Villa ComunaleBasilica di Santa Croce
Masseria PapapertaCasa D'AmoreTrulli di Alberobello PugliaTrullo Siamese monumento negozio souvenir
Belvedere di Piazza Giovanni PascoliSassi di MateraCattedrale di Maria Santissima della Bruna e Sant'EustachioPalombaro lungo
Costiera Amalfitana PositanoChiesa di Santa Maria AssuntaViewpoint.8-Amalfi Dr
Amalfi CoastPath of the LemonsVilla RufoloVilla Cimbrone GardensLi Cannati - Sentiero degli Dei

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Day 1

Day 1

  • Brindisi - Arrival day
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  • Lungomare Regina Margherita
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Welcome to Brindisi, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 1 night immersing yourself in Brindisi's charm before embarking on the next leg of your journey.

Brindisi is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Amici Dei Musei Brindisi, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Brindisi. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brindisi, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Bracerie Escosazio, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Penny offers an enticing alternative with its varied menu. Additionally, Piadineria is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Brindisi.

After your meal, keep the night alive at a bar like Peddy Bar. Pasticceria. Gelateria. Happyhour. Prodotti Celiaci. Slot Machines. Scommesse, known for its lively atmosphere. Eden Cafè is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Altair Cafè offers an excellent atmosphere for those looking to amp up the evening.

Raise a toast to the start of your 10-day road trip in Italy!

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Day 2

Day 2

  • Brindisi
  • Lecce
  • More

Drive 41 km, 1 hour 5 min

  • Porta Rudiae
  • Gate of Saint Blaise
  • Castello Carlo V
  • Giardini Pubblici Giuseppe Garibaldi - Villa Comunale
  • Basilica di Santa Croce
  • More

On day 2 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Lecce. In the evening, you’ll end up in Lecce, where you will stay for 3 nights.

Brindisi is brimming with adventures. Today’s wonderful stops include a monument, a castle, a park, a church and much more! Begin your sightseeing adventure at the curiosity-inducing Porta Rudiae and allow yourself time to explore. Just a short distance away you'll find your next stop, Gate Of Saint Blaise, a heritage-rich monument that draws visitors from far and near.

Continue your journey to Castle Of Charles V, one of the city’s most frequently visited spots that you shouldn’t miss. Another great site to visit is the up-and-coming Giardini Pubblici Giuseppe Garibaldi - Villa Comunale. When you're finished at the park, Basilica Di Santa Croce awaits your visit. This church is a culturally significant highlight on today's itinerary.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Lecce. Lecce offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Lecce's best restaurants.

Treat yourself to a wonderful meal at Alle due Corti, a top-rated dining spot in Lecce. If you're in the mood for something new, try Il Ristoro dei Templari Trattoria Pizzeria Braceria, another premier location with a delectable menu. You might also want to book a table at La Cucina di Mamma Elvira. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Lecce.

After enjoying a fulfilling meal, continue your evening at Sensi, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Caffè Alvino offers a welcoming atmosphere for easing into the nightlife. Similarly, Jolly Roger provides an excellent environment for a relaxed and enjoyable evening.

Savor another day of unforgettable experiences in Italy!

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Day 3

Day 3

  • Lecce
  • More

Drive 236 km, 2 hours 57 min

  • Masseria Papaperta
  • Casa D'Amore
  • Trulli di Alberobello Puglia
  • Trullo Siamese monumento negozio souvenir
  • More

Greet day 3 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Lecce for your remaining 2 nights in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Castellana Grotte and Alberobello.

Discover a day packed with fun adventures, breathtaking views, and picturesque spots in Lecce. Begin your sightseeing with Masseria Papaperta. This underrated sightseeing destination is one of the top attractions in the city. Proceed to Casa D'amore, another must-visit attraction.

As you wander through the inviting streets of Lecce, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Trulli Di Alberobello Puglia. This popular historical landmark is a traveler-favorite. Not far away, you’ll find Trullo Siamese - Negozio Souvenirs, another key site on your sightseeing itinerary.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Lecce.

After a day of adventure, treat yourself to an exquisite dinner at one of Lecce's best restaurants.

Make sure to reserve a table at Miro Coffee Bistrot & Lounge Bar, an iconic dining spot in Lecce. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Oscar Cafè, a popular restaurant in Lecce. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of La Vecchia Osteria da Totu, a hidden gem nestled in Lecce. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

If you’re not ready to end the night just yet, Bar Il Palio offers a perfect venue to relax and savor a drink. Similarly, Al Ventuno is well-suited for those looking to unwind in a social setting. Avio is another excellent spot to enjoy a nightcap after a delightful meal.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

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Day 4

Day 4

  • Lecce
  • More

Drive 363 km, 4 hours 36 min

  • Belvedere di Piazza Giovanni Pascoli
  • Sassi di Matera
  • Cattedrale di Maria Santissima della Bruna e Sant'Eustachio
  • Palombaro lungo
  • More

On day 4 of your road trip, you’ll start and end your day in Lecce, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Matera. You still have 1 night left in Lecce.

Get ready to discover some of the most iconic wonders in Lecce, including an observation deck, an archeological site, a church, a cave system and much more! Start your day at Belvedere Di Piazza Giovanni Pascoli. This enchanting observation deck is a frequently visited place to see in Lecce. Then, wander over to Sassi Di Matera. If UNESCO world heritage-listed sites excite you, this archeological site will be right up your alley. Nearby, you’ll also find Cattedrale Di Maria Santissima Della Bruna E Sant'eustachio. This breathtaking church is a favorite among visitors.

Lecce offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Palombaro Lungo is a frequently visited spot in the city that will captivate you with its unique charm.

When you’re done exploring for the day, you’ll return to Lecce and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat in Lecce. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at L'OSTRICA UBRIACA di viale della Libertà, a top-rated dining destination in Lecce. If you're in the mood to try something new, consider L'angolino di Via Matteotti, another top spot with a mouthwatering menu. You might also want to secure a reservation at Bar L'Incontro | Caffetteria, Pasticceria, Rosticceria. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Lecce this evening.

Following your dinner, dive into the local bar culture at Quanto Basta. Enjoy this evening's relaxed ambiance with delightful drinks.

Head back to your accommodation in Lecce and get some rest in preparation for another magical day of your road trip in Italy!

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Day 5

Day 5

  • Lecce
  • Naples
  • More

Drive 511 km, 6 hours 47 min

  • Costiera Amalfitana Positano
  • Chiesa di Santa Maria Assunta
  • Viewpoint.8-Amalfi Dr
  • More

Experience an unparalleled adventure on day 5 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Positano and Vico Equense. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Naples. You will spend 4 nights here for some well-deserved relaxation.

Set out on a day brimming with fun adventures, romantic experiences, and natural wonders. Start at the intriguing Costiera Amalfitana Positano, a romantic beach in Lecce. Next, go to Chiesa Di Santa Maria Assunta.

After visiting Costiera Amalfitana Positano and Chiesa Di Santa Maria Assunta, have a stroll along Lecce's streets and take in the local charm. Continue your sightseeing by heading to Viewpoint.8-amalfi Dr. This romantic observation deck offers a unique experience.

When you’re done exploring for the day, you’ll drive to your hotel in Naples. Check in and spend some time relaxing before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Naples. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Savor the flavors at L'Oca Nera Irish Pub, a top pick for dinner tonight. Alternatively, Mimì alla Ferrovia beckons with its unique menu offerings. Also, consider Spuzzulè Winebar. With its consistent customer satisfaction, it’s an excellent option for dining in Naples tonight.

Unwind after your meal by stepping into Happening Cocktail Bar. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Shanti Art Musik Bar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Gran Caffè Gambrinus, another top-rated bar in the area.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 6

Day 6

  • Naples
  • More

Drive 146 km, 4 hours 19 min

  • Amalfi Coast
  • Path of the Lemons
  • Villa Rufolo
  • Villa Cimbrone Gardens
  • Li Cannati - Sentiero degli Dei
  • More

On day 6 of your road trip, you’ll start and end your day in Naples, where you'll stay for 3 nights more.

Immerse yourself in Naples’s rich culture with today's sightseeing itinerary. Start your journey at Amalfi Coast. Next, dive into the romantic features of Path Of The Lemons, a must-visit hiking area in the village.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Villa Rufolo, a well-known historical landmark. For a change of scene, check out Villa Cimbrone Gardens, known for its detailed features. We also recommend visiting Li Cannati - Sentiero Degli Dei. This hiking area is a must for anyone looking to experience the village to the fullest.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Naples.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Naples. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at Antica Pizzeria Di Matteo, a highly-rated dining destination in Naples. If you're eager to try something different, consider Mercure Napoli Centro Angioino, another top spot with a tantalizing menu. You might also want to secure a reservation at La Lazzara Trattoria e Pizzeria. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Naples this evening.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Archivio Storico - Cocktail Bar & Wonderfood, a well-loved spot among locals and tourists. Or, head to Archeobar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Babette Pub, another top-rated place in the area.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 7

Day 7

  • Naples
  • More

Drive 9 km, 1 hour 23 min

  • Naples National Archaeological Museum
  • Cappella Sansevero
  • piazza del Plebiscito
  • Ovo Castle
  • Via Toledo
  • More

Day 7 of your road trip across Italy promises a magnificent time exploring Naples. You have 2 nights left in Naples. Take the opportunity to experience more of the best attractions and activities in the city.

Set aside time today to explore Via Toledo, a standout street that reflects the essence of the city. While you're there, you'll also be within reach of some of the city's top landmarks, making it easy to maximize your day.

Get ready for an exciting day in Naples. Today’s sightseeing agenda includes a museum, a public square, and a castle. Begin your adventure at Naples National Archaeological Museum. This is a locally renowned museum you should not miss. Another must-see is Cappella Sansevero, an interesting museum in Naples.

When you’re ready for the next sight, head to Piazza Del Plebiscito. From there, take a leisurely stroll to Ovo Castle, another of the city’s notable attractions.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Indulge in a memorable dining experience at one of Naples's most popular restaurants, and connect with friendly locals for an authentic adventure.

Savor the flavors at Opera Restaurant, a top pick for dinner tonight. Alternatively, Trattoria San Ferdinando beckons with its unique menu offerings. Also, consider Anonymous Trattoria Gourmet. With its consistent customer satisfaction, it’s an excellent option for dining in Naples tonight.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Gran Caffè Cimmino stands out as an excellent choice for a post-dinner cocktail. Alternatively, Flanagan's Bar offers an ideal atmosphere to enjoy the pleasures of the night. Bar Napoli is also a great option that provides a perfect setting for a relaxing evening.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 8

Day 8

  • Naples
  • More

Drive 56 km, 1 hour 41 min

  • Amphitheatre of Pompeii
  • Teatro Grande
  • Lupanar des esclaves
  • House of the Vettii
  • Archaeological Park of Pompeii
  • More

On day 8 of your road trip in Italy, you’ll start and end your day in Naples, but spend the day exploring what’s beyond the city. Since you will return to Naples for 1 night more, there’s no need to rush. Experience Pompei to the fullest today with this curated day itinerary!

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Naples allows for both. Start by heading to Amphitheatre Of Pompeii. This notable archeological site provides an insightful glimpse into the town's identity. Next, discover Teatro Grande, a historic archeological site, promising a delightful encounter.

Continue your sightseeing with a visit to Lupanare Di Pompei, a beloved archeological site. When you’re done, don’t forget to make a stop at the intriguing House Of The Vettii. Round off your day at Archaeological Park Of Pompeii, another gem in Naples with historic features to discover.

When you’re done exploring for the day, you’ll return to Naples and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Naples. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Dine in style at Piazza Sannazaro, a top recommendation for dinner tonight. Or, for a change of pace, Osteria Il Gobbetto boasts a menu that's sure to impress. Also, be sure to check out Trattoria Castel Nuovo. Known as a local hotspot, it’s a great choice for tonight in Naples.

Let the evening flow smoothly from dinner to drinks at Parthenope Bar, a top-rated bar in the area. For other recommendations, Gran Caffè Mexico provides a perfect setting for rounding out your night with style and great drinks. Likewise, Novecento Wine Bar offers a memorable night with diverse drink options and excellent service.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 9

Day 9

  • Naples
  • Brindisi
  • More

Drive 392 km, 4 hours 41 min

  • CENTRO STORICO
  • Colonna di Sant'Oronzo
  • Castello Dentice di Frasso di Carovigno
  • More

Embark on another extraordinary experience on day 9 of your road trip in Italy. Today, you will make 2 stops and experience some of the highlights of Ostuni and Carovigno. At the end of the day, you will enjoy the comforts of a top-rated hotel in Brindisi, which will be your home away from home for 1 night.

Today’s route brings fun adventures, romantic experiences, and breathtaking views. The first attraction of today is Centro Storico. This often recommended historical landmark is a visually striking place to see in Naples. Continue your discovery at Guglia Di Sant'oronzo, a picture-perfect monument with stories to tell.

As you stroll around Naples, take in the distinct atmosphere and learn what makes this town so unique. Maximize your sightseeing with a visit to Castello Dentice Di Frasso Di Carovigno. This beloved castle offers an enchanting encounter with Naples. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Naples.

At the end of the day, you will drive to Brindisi, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Brindisi. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Make sure to reserve a table at Betty - Gelateria Cafe Ristorante Pizzeria a Brindisi, an iconic dining spot in Brindisi. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bento, a popular restaurant in Brindisi. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Cozza Nera, a hidden gem nestled in Brindisi. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

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Day 10

Day 10

  • Brindisi - Departure day
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  • Cillarese Park
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Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Brindisi before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Cillarese Park, a picturesque park before you head out.

Make the most of your final day in Italy by visiting Brindisi’s iconic markets and shopping establishments. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Italy.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Brindisi.

Have a fantastic dining experience at Rendez-Vous Cafè Bistrot, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Pizzeria La Nassa offers an enticing alternative with its varied menu.

You’ll then say farewell to Brindisi. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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