10-Day Italy Self-Drive Road Trip With Itinerary from Brindisi to Lecce and Naples

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Ostuni white town skyline at sunset, Brindisi, Apulia southern Italy. Europe.
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Escape the ordinary with this exciting 10-day road trip through Italy. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 2 nights in Brindisi, 3 nights in Lecce, and 4 nights in Naples. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Brindisi, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Amalfi Coast and Piazza Del Plebiscito are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Brindisi, Lecce, Castellana Grotte, Alberobello, Matera, Positano, Vico Equense, Naples, Amalfi, Minori, Ravello, Bomerano, Pompei, Ostuni, and Carovigno, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day1

Day 1

  • Brindisi - Arrival day
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  • Lungomare Regina Margherita
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Your road trip adventure in Italy begins as soon as you reach Brindisi and pick up your car. You’ll stay here for 1 night and explore what to see in Brindisi, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Brindisi is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Amici Dei Musei Brindisi. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Brindisi. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brindisi, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Bracerie Escosazio, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Penny offers an enticing alternative with its varied menu. Additionally, Piadineria is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Brindisi.

Round off your dining experience by visiting Peddy Bar. Pasticceria. Gelateria. Happyhour. Prodotti Celiaci. Slot Machines. Scommesse, a prime location for a drink. Alternatively, explore the distinctive characteristics of Eden Cafè, a bar catering to every mood and preference. Altair Cafè likewise offers a unique atmosphere, perfect for a memorable night out.

Raise a toast to the start of your 10-day road trip in Italy!

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Day2

Day 2

  • Brindisi
  • Lecce
  • More

Drive 41 km, 1 hour 5 min

  • Porta Rudiae
  • Gate of Saint Blaise
  • Castello Carlo V
  • Giardini Pubblici Giuseppe Garibaldi - Villa Comunale
  • Basilica di Santa Croce
  • More

On day 2 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Lecce are on today's agenda. In the evening, you’ll end up in Lecce, where you will stay for 3 nights.

Look forward to a unique sightseeing adventure at the often recommended Porta Rudiae and allow yourself time to explore. Just a short distance away you'll find your next stop, Gate Of Saint Blaise, a photogenic monument that draws visitors from far and near.

Continue your journey to Castle Of Charles V, one of the city’s most up-and-coming spots that you shouldn’t miss. Another great site to visit is the increasingly popular Giardini Pubblici Giuseppe Garibaldi - Villa Comunale. When you're finished at the park, Basilica Di Santa Croce awaits your visit. This church is a heritage-rich highlight on today's itinerary.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Lecce. Lecce offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Lecce's most popular restaurants, and connect with friendly locals for a true cultural experience.

Make sure to reserve a table at Alle due Corti, an iconic dining spot in Lecce. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Il Ristoro dei Templari Trattoria Pizzeria Braceria, a popular restaurant in Lecce. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of La Cucina di Mamma Elvira, a hidden gem nestled in Lecce. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After enjoying a fulfilling meal, continue your evening at Sensi, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Caffè Alvino offers a welcoming atmosphere for easing into the nightlife. Similarly, Jolly Roger provides an excellent environment for a relaxed and enjoyable evening.

Relax and recharge in preparation for another adventurous day in Italy!

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Day3

Day 3

  • Lecce
  • More

Drive 236 km, 2 hours 57 min

  • Masseria Papaperta
  • Casa D'Amore
  • Trulli di Alberobello Puglia
  • Trullo Siamese monumento negozio souvenir
  • More

Greet day 3 of your road trip in Italy with a smile and start your day with a hearty breakfast. You have 2 nights to stay in Lecce, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Castellana Grotte and Alberobello.

Masseria Papaperta brings Lecce's character to life. Then, enjoy Casa D'amore, another standout attraction that never fails to captivate visitors. Next, head over to Trulli Di Alberobello Puglia, one of the city’s most well-known attractions, known for its romantic features.

If you’re looking for more, spend time soaking in the atmosphere of Trullo Siamese - Negozio Souvenirs. This eye-catching gift shop is frequented by locals and tourists alike. To complete your memorable day, make sure to take a stroll around the area.

When you’re done exploring for the day, you’ll return to Lecce and your accommodation.

Indulge in a memorable dining experience at one of Lecce's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a delightful dinner at Miro Coffee Bistrot & Lounge Bar, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Oscar Cafè? It's another excellent option with a diverse menu. Consider reserving a table at La Vecchia Osteria da Totu as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Lecce.

Cap off your dinner by heading to Bar Il Palio, ideal for a leisurely evening with a drink in hand. Al Ventuno is another bar that offers an enjoyable setting. Similarly, Avio is also a popular place to go on a night out, perfect for relaxing and socializing.

Relax and look forward to more memorable moments to come!

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Day4

Day 4

  • Lecce
  • More

Drive 363 km, 4 hours 36 min

  • Belvedere di Piazza Giovanni Pascoli
  • Sassi di Matera
  • Cattedrale di Maria Santissima della Bruna e Sant'Eustachio
  • Palombaro lungo
  • More

On day 4 of your road trip, you’ll start and end your day in Lecce, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate city, including Matera.

Belvedere Di Piazza Giovanni Pascoli is an ideal stop early in the day. This underrated observation deck is a must-visit in the city. When you’re ready for your next discovery, continue to Sassi Di Matera, which may be one of the most history-steeped places you will experience today.

One of the best things about exploring Lecce on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Cattedrale Di Maria Santissima Della Bruna E Sant'eustachio, a curiosity-inducing church in the city. If you’re up for more discoveries, don’t forget to reserve some time for Palombaro Lungo.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Lecce.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Lecce. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Dine in style at L'OSTRICA UBRIACA di viale della Libertà, a top recommendation for dinner tonight. Or, for a change of pace, L'angolino di Via Matteotti boasts a menu that's sure to impress. Also, be sure to check out Bar L'Incontro | Caffetteria, Pasticceria, Rosticceria. Known as a local hotspot, it’s a great choice for tonight in Lecce.

Continue your lively evening at Quanto Basta, a perfect place for winding down or revving up the night, depending on which mood you’re in.

Raise your glass to another unforgettable day in Italy!

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Day5

Day 5

  • Lecce
  • Naples
  • More

Drive 511 km, 6 hours 47 min

  • Costiera Amalfitana Positano
  • Chiesa di Santa Maria Assunta
  • Viewpoint.8-Amalfi Dr
  • More

Dive into day 5 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Positano and Vico Equense. At the end of the day, you’ll unwind at one of the finest accommodations in Naples, where you'll spend 4 nights.

Make a stop at Costiera Amalfitana Positano. This curiosity-inducing beach is a must-visit for travelers looking for a unique holiday experience. Make your way to Chiesa Di Santa Maria Assunta located in Lecce for another exciting encounter.

Next, immerse yourself in the setting of Viewpoint.8-amalfi Dr. Its visually striking features will captivate you.

At the end of the day, you will drive to Naples, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Naples, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at L'Oca Nera Irish Pub, a highly-rated dining destination in Naples. If you're eager to try something different, consider Mimì alla Ferrovia, another top spot with a tantalizing menu. You might also want to secure a reservation at Spuzzulè Winebar. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Naples this evening.

Continue the enjoyment post-dinner at Happening Cocktail Bar, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Shanti Art Musik Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation. You may also want to check out Gran Caffè Gambrinus. This bar is a favorite among both locals and visitors looking for a delightful evening out filled with laughter and fun.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day6

Day 6

  • Naples
  • More

Drive 146 km, 4 hours 19 min

  • Amalfi Coast
  • Path of the Lemons
  • Villa Rufolo
  • Villa Cimbrone Gardens
  • Li Cannati - Sentiero degli Dei
  • More

On day 6 of your road trip in Italy, you’ll start and end your day in Naples, but spend the day exploring what’s beyond the city. Since you still have 3 nights to spend in Naples, there’s no need to rush. Experience Amalfi, Minori, Ravello, Castiglione, and Bomerano to the fullest today with this curated day itinerary.

Your adventure in Naples is only getting started when you visit Amalfi Coast, a top-rated local hot spot. Another notable attraction to explore is Path Of The Lemons.

After soaking in the highlights of these sights, take some time to wander Naples's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Villa Rufolo. This visually striking historical landmark offers a fascinating experience that many visitors find memorable. Villa Cimbrone Gardens is also worth visiting, along with Li Cannati - Sentiero Degli Dei. These standout landmarks offer unique experiences that add to the day’s enjoyment.

When you’re done exploring for the day, you’ll return to Naples and your accommodation.

After a day of adventure, treat yourself to an exquisite dinner at one of Naples's best restaurants.

Enjoy a lovely meal at Antica Pizzeria Di Matteo, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Mercure Napoli Centro Angioino is another top choice with a popular menu. You could also check for a table at La Lazzara Trattoria e Pizzeria. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Naples tonight.

Continue your evening by exploring the vibrant nightlife scene at Archivio Storico - Cocktail Bar & Wonderfood, a prime destination for a thrilling night out. Also, don’t forget to check out Archeobar, a bar that offers unique local touches. Likewise, Babette Pub provides an excellent alternative for a fun evening.

Savor another day of unforgettable experiences in Italy!

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Day7

Day 7

  • Naples
  • More

Drive 9 km, 1 hour 23 min

  • Naples National Archaeological Museum
  • Cappella Sansevero
  • piazza del Plebiscito
  • Ovo Castle
  • Via Toledo
  • More

On day 7 of your road trip, you will have an entire day to discover what to see in Naples. You’ll stay in Naples for 2 nights.

Via Toledo is a fantastic place you can explore today in Naples. This street is a testament to the city’s character, and it's easy to spend hours just walking around and admiring the surroundings. Soak in the Naples-way-of-life and visit all the nearby sights.

Enjoy all that Naples National Archaeological Museum has to offer. This is a locally renowned museum you should not miss. Another must-see is Cappella Sansevero, a popular museum in Naples.

When you’re ready for the next sight, head to Piazza Del Plebiscito. From there, take a leisurely stroll to Ovo Castle, another of the city’s popular attractions.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Naples's best restaurants.

Have a fantastic dining experience at Opera Restaurant, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Trattoria San Ferdinando offers an enticing alternative with its varied menu. Additionally, Anonymous Trattoria Gourmet is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Naples.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Gran Caffè Cimmino, known for its inviting atmosphere. Flanagan's Bar is another great option if you’re looking for a place to get the night started. Similarly, Bar Napoli provides a great setting to enjoy the night away.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day8

Day 8

  • Naples
  • More

Drive 56 km, 1 hour 41 min

  • Amphitheatre of Pompeii
  • Teatro Grande
  • Lupanar des esclaves
  • House of the Vettii
  • Archaeological Park of Pompeii
  • More

Wake up to day 8 of your road trip in Italy. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Pompei. With 1 night to stay in Naples, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Whatever your travel style is, Amphitheatre Of Pompeii is an essential stop in Naples. This captivating archeological site provides an insightful glimpse into the town's identity. Next, discover Teatro Grande, an UNESCO world heritage-designated archeological site, promising a delightful encounter.

Continue your sightseeing with a visit to Lupanare Di Pompei, an up-and-coming archeological site. When you’re done, don’t forget to make a stop at the often recommended House Of The Vettii. Round off your day at Archaeological Park Of Pompeii, another gem in Naples with awe-inspiring features to discover.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Naples.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Naples, it's often a good idea to reserve a table in advance.

Have a fantastic dining experience at Piazza Sannazaro, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Osteria Il Gobbetto offers an enticing alternative with its varied menu. Additionally, Trattoria Castel Nuovo is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Naples.

Keep the excitement of the evening going by visiting a bar or two. Parthenope Bar is an excellent place to start. You could also check out Gran Caffè Mexico, offering a different kind of charm. A last recommendation for the day is Novecento Wine Bar. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day9

Day 9

  • Naples
  • Brindisi
  • More

Drive 392 km, 4 hours 41 min

  • CENTRO STORICO
  • Colonna di Sant'Oronzo
  • Castello Dentice di Frasso di Carovigno
  • More

Your itinerary for day 9 of your road trip in Italy includes 2 stops and features some of the highlights of Ostuni and Carovigno. At the end of the day, enjoy the comforts of a top-rated hotel in Brindisi, where you'll spend 1 night.

Centro Storico is an ideal stop early in the day. This frequently visited historical landmark is a must-visit in the town. When you’re ready for your next discovery, continue to Guglia Di Sant'oronzo, which may be one of the most historic places you will experience today.

One of the best things about exploring Naples on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Castello Dentice Di Frasso Di Carovigno, a locally appreciated castle in the town.

When you’re done exploring for the day, you’ll drive to your hotel in Brindisi. Check in and relax before you head out to tour the city.

Brindisi is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Brindisi.

Make sure to reserve a table at Betty - Gelateria Cafe Ristorante Pizzeria a Brindisi, an iconic dining spot in Brindisi. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Bento, a popular restaurant in Brindisi. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Cozza Nera, a hidden gem nestled in Brindisi. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Raise your glass to another unforgettable day in Italy!

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Day10

Day 10

  • Brindisi - Departure day
  • More
  • Cillarese Park
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Brindisi before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Cillarese Park. This curiosity-inducing park is a hotspot among locals.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Brindisi.

If you're in the mood to try something new, consider Pizzeria La Nassa, another top spot with a mouthwatering menu.

You’ll then say farewell to Brindisi. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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