10-Day Italy Self-Drive Road Trip With Itinerary from Brindisi to Lecce and Naples

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Ostuni white town skyline at sunset, Brindisi, Apulia southern Italy. Europe.
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Experience the freedom of the open road in Italy as you embark on an unforgettable 10-day road trip! This experience caters to every traveler, featuring destinations like Brindisi, Lecce, Castellana Grotte, Alberobello, Matera, Positano, Vico Equense, Naples, Amalfi, Minori, Ravello, Bomerano, Pompei, Ostuni, and Carovigno.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 2 nights in Brindisi, 3 nights in Lecce, and 4 nights in Naples. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Brindisi, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Amalfi Coast and Piazza Del Plebiscito are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Archaeological Park Of Pompeii, learn more about the unique Sassi Di Matera, and immerse yourself in the vibrant atmosphere of Ovo Castle.

As you hit the open road and drive through Brindisi, Lecce, Castellana Grotte, Alberobello, Matera, Positano, Vico Equense, Naples, Amalfi, Minori, Ravello, Bomerano, Pompei, Ostuni, and Carovigno, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Day 1

Day 1

  • Brindisi - Arrival day
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  • Lungomare Regina Margherita
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Your road trip adventure in Italy begins as soon as you reach Brindisi and pick up your car. You’ll stay in Brindisi for 1 night and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Brindisi is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Amici Dei Musei Brindisi, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Brindisi. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brindisi, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Bracerie Escosazio, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Penny? It's another excellent option with a diverse menu. Consider reserving a table at Piadineria as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Brindisi.

Explore the vibrant nightlife at Peddy Bar. Pasticceria. Gelateria. Happyhour. Prodotti Celiaci. Slot Machines. Scommesse after your meal, a hub for lively evenings and memorable moments. Or, head to Eden Cafè for a great selection of flavorful drinks and a charming setting. Furthermore, Altair Cafè is perfect for those looking to extend their night with a touch of local flavor.

Raise a toast to the start of your 10-day road trip in Italy!

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Day 2

Day 2

  • Brindisi
  • Lecce
  • More

Drive 41 km, 1 hour 5 min

  • Porta Rudiae
  • Gate of Saint Blaise
  • Castello Carlo V
  • Giardini Pubblici Giuseppe Garibaldi - Villa Comunale
  • Basilica di Santa Croce
  • More

Experience an unparalleled adventure on day 2 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Lecce. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Lecce. You will spend 3 nights here for some well-deserved relaxation.

Brindisi is brimming with adventures. Today’s wonderful stops include a monument, a castle, a park, a church and much more! Begin your sightseeing adventure at the curiosity-inducing Porta Rudiae and allow yourself time to explore. Just a short distance away you'll find your next stop, Gate Of Saint Blaise, a symbolic monument that draws visitors from far and near.

Continue your journey to Castle Of Charles V, one of the city’s most worthwhile spots that you shouldn’t miss. Another great site to visit is the underrated Giardini Pubblici Giuseppe Garibaldi - Villa Comunale. When you're finished at the park, Basilica Di Santa Croce awaits your visit. This church is a heritage-rich highlight on today's itinerary.

At the end of the day, you will drive to Lecce, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Lecce. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Dine in style at Alle due Corti, a top recommendation for dinner tonight. Or, for a change of pace, Il Ristoro dei Templari Trattoria Pizzeria Braceria boasts a menu that's sure to impress. Also, be sure to check out La Cucina di Mamma Elvira. Known as a local hotspot, it’s a great choice for tonight in Lecce.

Keep the excitement of the evening going by visiting a bar or two. Sensi is an excellent place to start. You could also check out Caffè Alvino, offering a different kind of charm. A last recommendation for the day is Jolly Roger. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 3

Day 3

  • Lecce
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Drive 236 km, 2 hours 57 min

  • Masseria Papaperta
  • Casa D'Amore
  • Trulli di Alberobello Puglia
  • Trullo Siamese monumento negozio souvenir
  • More

Wake up to day 3 of your extraordinary road trip in Italy. With 2 nights left in Lecce, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

A blend of fun adventures, breathtaking views, and photo-friendly spots await you in Lecce on today’s itinerary. First up is the increasingly popular sightseeing destination, Masseria Papaperta. Afterward, continue to Casa D'amore, a historical landmark every traveler should visit.

As you explore Lecce’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Trulli Di Alberobello Puglia. This well-known historical landmark is an essential stop. Following that, head to Trullo Siamese - Negozio Souvenirs, another must-visit site that will enhance your experience.

When you’re done exploring for the day, you’ll return to Lecce and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Lecce. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a delicious meal at Miro Coffee Bistrot & Lounge Bar, a highly-rated dining destination in Lecce. If you're eager to try something different, consider Oscar Cafè, another top spot with a tantalizing menu. You might also want to secure a reservation at La Vecchia Osteria da Totu. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Lecce this evening.

Explore the vibrant nightlife at Bar Il Palio after your meal, a hub for lively evenings and memorable moments. Or, head to Al Ventuno for a great selection of flavorful drinks and a charming setting. Furthermore, Avio is perfect for those looking to extend their night with a touch of local flavor.

Say good night to Lecce and look forward to another great day of your road trip in Italy!

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Day 4

Day 4

  • Lecce
  • More

Drive 363 km, 4 hours 36 min

  • Belvedere di Piazza Giovanni Pascoli
  • Sassi di Matera
  • Cattedrale di Maria Santissima della Bruna e Sant'Eustachio
  • Palombaro lungo
  • More

On day 4 of your road trip, you’ll start and end your day in Lecce, where you'll stay for 1 night more.

Brace yourself for today’s incredible lineup of attractions in Lecce, featuring fun adventures, romantic experiences, and scenic views. Start at Belvedere Di Piazza Giovanni Pascoli, an up-and-coming observation deck in the city. Then, head to Sassi Di Matera and soak in the ambiance of this UNESCO world heritage-designated archeological site.

There are many interesting places to see in Lecce, and when you are ready for more, go to Cattedrale Di Maria Santissima Della Bruna E Sant'eustachio. This is one of the city’s most underrated UNESCO world heritage-listed spots of interest. After exploring the church, visit the often recommended Palombaro Lungo.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Lecce.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Lecce. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Don’t miss out on dining at L'OSTRICA UBRIACA di viale della Libertà, a top-rated dining destination in Lecce. If you're in the mood to try something new, consider L'angolino di Via Matteotti, another top spot with a mouthwatering menu. You might also want to secure a reservation at Bar L'Incontro | Caffetteria, Pasticceria, Rosticceria. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Lecce this evening.

Continue your evening by exploring the vibrant nightlife scene at Quanto Basta, a prime destination for a thrilling night out.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

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Day 5

Day 5

  • Lecce
  • Naples
  • More

Drive 511 km, 6 hours 47 min

  • Costiera Amalfitana Positano
  • Chiesa di Santa Maria Assunta
  • Viewpoint.8-Amalfi Dr
  • More

On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Positano and Vico Equense. When you’re not sightseeing, take time to relax at your selected hotel in Naples, where you’ll be staying for 4 nights.

Savor the day by visiting some of the best places to see in Lecce, including a beach, a church, and an observation deck. Start your adventure at Costiera Amalfitana Positano. This curiosity-inducing beach is a must-visit for travelers looking for a unique holiday experience. Make your way to Chiesa Di Santa Maria Assunta located in Lecce for another exciting encounter.

Next, immerse yourself in the setting of Viewpoint.8-amalfi Dr. Its stunning features will captivate you.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Naples. Naples offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Naples. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Savor the flavors at L'Oca Nera Irish Pub, a top pick for dinner tonight. Alternatively, Mimì alla Ferrovia beckons with its unique menu offerings. Also, consider Spuzzulè Winebar. With its consistent customer satisfaction, it’s an excellent option for dining in Naples tonight.

Round off your dining experience by visiting Happening Cocktail Bar, a prime location for a drink. Alternatively, explore the distinctive characteristics of Shanti Art Musik Bar, a bar catering to every mood and preference. Gran Caffè Gambrinus likewise offers a unique atmosphere, perfect for a memorable night out.

As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.

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Day 6

Day 6

  • Naples
  • More

Drive 146 km, 4 hours 19 min

  • Amalfi Coast
  • Path of the Lemons
  • Villa Rufolo
  • Villa Cimbrone Gardens
  • Li Cannati - Sentiero degli Dei
  • More

At the end of the day, you'll drive back to Naples, where you'll stay for 3 nights more.

Set out on a day brimming with fun adventures, romantic experiences, and natural wonders. Next, go to Path Of The Lemons.

After visiting Amalfi Coast and Path Of The Lemons, have a stroll along Naples's streets and take in the local charm. Continue your sightseeing by heading to Villa Rufolo. This visually striking historical landmark offers a unique experience. Villa Cimbrone Gardens is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Li Cannati - Sentiero Degli Dei, one of the most eye-catching places to visit in Naples.

When you’re done exploring for the day, you’ll return to Naples and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat in Naples. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Savor the flavors at Antica Pizzeria Di Matteo, a top pick for dinner tonight. Alternatively, Mercure Napoli Centro Angioino beckons with its unique menu offerings. Also, consider La Lazzara Trattoria e Pizzeria. With its consistent customer satisfaction, it’s an excellent option for dining in Naples tonight.

Cap off your dinner by heading to Archivio Storico - Cocktail Bar & Wonderfood, ideal for a leisurely evening with a drink in hand. Archeobar is another bar that offers an enjoyable setting. Similarly, Babette Pub is also a popular place to go on a night out, perfect for relaxing and socializing.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

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Day 7

Day 7

  • Naples
  • More

Drive 9 km, 1 hour 23 min

  • Naples National Archaeological Museum
  • Cappella Sansevero
  • piazza del Plebiscito
  • Ovo Castle
  • Via Toledo
  • More

Day 7 of your road trip will take you to the best attractions Naples has to offer. Cherish the 2 nights you have left in Naples by discovering the best things there are to see and do in the city.

Via Toledo is a street that stands out as one of the must-see places in Naples. Take a moment to explore its distinct atmosphere, and don’t miss the popular sightseeing spots just a short walk away.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Naples allows for both. Start by heading to Naples National Archaeological Museum. This notable museum provides an insightful glimpse into the city's identity. Next, discover Cappella Sansevero, a detailed museum, promising a delightful encounter.

Continue your sightseeing with a visit to Piazza Del Plebiscito, a famous public square. When you’re done, don’t forget to make a stop at the popular Ovo Castle.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a day of adventure, treat yourself to an exquisite dinner at one of Naples's best restaurants.

Have a fantastic dining experience at Opera Restaurant, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Trattoria San Ferdinando offers an enticing alternative with its varied menu. Additionally, Anonymous Trattoria Gourmet is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Naples.

Continue your evening by exploring the vibrant nightlife scene at Gran Caffè Cimmino, a prime destination for a thrilling night out. Also, don’t forget to check out Flanagan's Bar, a bar that offers unique local touches. Likewise, Bar Napoli provides an excellent alternative for a fun evening.

Raise your glass to another unforgettable day in Italy!

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Day 8

Day 8

  • Naples
  • More

Drive 56 km, 1 hour 41 min

  • Amphitheatre of Pompeii
  • Teatro Grande
  • Lupanar des esclaves
  • House of the Vettii
  • Archaeological Park of Pompeii
  • More

On day 8 of your road trip, you’ll start and end your day in Naples, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Pompei. You still have 1 night left in Naples.

Start your day with a visit to Amphitheatre Of Pompeii. This notable archeological site is a must-visit in the town. When you’re ready for your next discovery, continue to Teatro Grande, which may be one of the most UNESCO world heritage-designated places you will experience today.

One of the best things about exploring Naples on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Lupanare Di Pompei, a beloved archeological site in the town. If you’re up for more discoveries, don’t forget to reserve some time for House Of The Vettii and Archaeological Park Of Pompeii.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Naples.

Indulge in a memorable dining experience at one of Naples's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a delightful dinner at Piazza Sannazaro, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Osteria Il Gobbetto? It's another excellent option with a diverse menu. Consider reserving a table at Trattoria Castel Nuovo as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Naples.

After your meal, keep the night alive at a bar like Parthenope Bar, known for its lively atmosphere. Gran Caffè Mexico is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Novecento Wine Bar offers an excellent atmosphere for those looking to amp up the evening.

Savor another day of unforgettable experiences in Italy!

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Day 9

Day 9

  • Naples
  • Brindisi
  • More

Drive 392 km, 4 hours 41 min

  • CENTRO STORICO
  • Colonna di Sant'Oronzo
  • Castello Dentice di Frasso di Carovigno
  • More

Embark on another extraordinary experience on day 9 of your road trip in Italy. Today, you will make 2 stops and experience some of the highlights of Ostuni and Carovigno. At the end of the day, you will enjoy the comforts of a top-rated hotel in Brindisi, which will be your home away from home for 1 night.

Start by visiting Centro Storico, a prime spot to begin your journey. This visually striking historical landmark is sure to impress. Next on your list is Guglia Di Sant'oronzo, another must-visit landmark and beloved monument renowned for its culturally significant features.

While exploring and sightseeing, take time to savor the culture of Naples by sampling some local delicacies. When you’re ready for more sightseeing, head to Castello Dentice Di Frasso Di Carovigno. This visually striking castle is an essential place to visit for anyone looking for the full Naples experience.

When you’re done exploring for the day, you’ll drive to your hotel in Brindisi. Check in and spend some time relaxing before you head out to tour the city.

Indulge in a memorable dining experience at one of Brindisi's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a delicious dinner at Betty - Gelateria Cafe Ristorante Pizzeria a Brindisi, an excellent option for tonight's dining. Looking for something different? Bento offers a tantalizing alternative with its diverse menu. And don’t miss Cozza Nera. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Brindisi.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 10

Day 10

  • Brindisi - Departure day
  • More
  • Cillarese Park
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Brindisi before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Cillarese Park. This often recommended park is a popular place to see in the city.

Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Brindisi.

You’ll then say farewell to Brindisi. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
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Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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