10-Day Italy Self-Drive Road Trip With Itinerary from Brindisi to Lecce and Naples

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Ostuni white town skyline at sunset, Brindisi, Apulia southern Italy. Europe.
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Escape the ordinary with this exciting 10-day road trip through Italy. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 2 nights in Brindisi, 3 nights in Lecce, and 4 nights in Naples. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Brindisi, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Amalfi Coast and Piazza Del Plebiscito are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Archaeological Park Of Pompeii, learn more about the unique Sassi Di Matera, and immerse yourself in the vibrant atmosphere of Ovo Castle.

As you hit the open road and drive through Brindisi, Lecce, Castellana Grotte, Alberobello, Matera, Positano, Vico Equense, Naples, Amalfi, Minori, Ravello, Bomerano, Pompei, Ostuni, and Carovigno, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Day 1

Day 1

  • Brindisi - Arrival day
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  • Lungomare Regina Margherita
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Say hello to Brindisi! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Brindisi for 1 night before you continue your adventure!

Brindisi is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Amici Dei Musei Brindisi, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Brindisi. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brindisi, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at Bracerie Escosazio, a popular restaurant in Brindisi. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Brindisi at Penny, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Piadineria. It’s yet another ideal choice to enhance your time in Brindisi tonight.

Keep the evening going at Peddy Bar. Pasticceria. Gelateria. Happyhour. Prodotti Celiaci. Slot Machines. Scommesse, a great choice for enjoying the after-dinner hours with a drink. You could also go to Eden Cafè, which offers a similarly pleasant setting and great drinks. Another option is Altair Cafè, which provides an inviting environment for unwinding after a busy day out.

Raise a toast to the start of your 10-day road trip in Italy!

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Day 2

Day 2

  • Brindisi
  • Lecce
  • More

Drive 41 km, 1 hour 5 min

  • Porta Rudiae
  • Gate of Saint Blaise
  • Castello Carlo V
  • Giardini Pubblici Giuseppe Garibaldi - Villa Comunale
  • Basilica di Santa Croce
  • More

Dive into day 2 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Lecce. At the end of the day, you’ll unwind at one of the finest accommodations in Lecce, where you'll spend 3 nights.

No visit to Brindisi is complete without Porta Rudiae. This often recommended monument is one of the top attractions in the city. Proceed to Gate Of Saint Blaise, another must-visit attraction.

As you wander through the inviting streets of Brindisi, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Castle Of Charles V. This worthwhile castle is a traveler-favorite. Not far away, you’ll find Giardini Pubblici Giuseppe Garibaldi - Villa Comunale, another key site on your sightseeing itinerary. Basilica Di Santa Croce is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.

When you’re done exploring for the day, you’ll drive to your hotel in Lecce. Check in and relax before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Lecce, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Alle due Corti, an iconic dining spot in Lecce. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Il Ristoro dei Templari Trattoria Pizzeria Braceria, a popular restaurant in Lecce. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of La Cucina di Mamma Elvira, a hidden gem nestled in Lecce. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Continue your lively evening at Sensi, a perfect place for winding down or revving up the night, depending on which mood you’re in. Caffè Alvino is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Jolly Roger ensures a night out tailored to your taste.

Say good night to Lecce and look forward to another great day of your road trip in Italy!

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Day 3

Day 3

  • Lecce
  • More

Drive 236 km, 2 hours 57 min

  • Masseria Papaperta
  • Casa D'Amore
  • Trulli di Alberobello Puglia
  • Trullo Siamese monumento negozio souvenir
  • More

Wake up to day 3 of your road trip in Italy. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Castellana Grotte and Alberobello. With 2 nights to stay in Lecce, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Castellana Grotte is brimming with adventures.

Start your day at Masseria Papaperta. Then, wander over to Casa D'amore. If historic sites excite you, this historical landmark will be right up your alley. Nearby, you’ll also find Trulli Di Alberobello Puglia. This UNESCO world heritage-designated historical landmark is a favorite among visitors.

Lecce offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Trullo Siamese - Negozio Souvenirs is an underrated spot in the city that will captivate you with its unique charm.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Lecce.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Lecce, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Miro Coffee Bistrot & Lounge Bar, a top-rated dining spot in Lecce. If you're in the mood for something new, try Oscar Cafè, another premier location with a delectable menu. You might also want to book a table at La Vecchia Osteria da Totu. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Lecce.

Explore the vibrant nightlife at Bar Il Palio after your meal, a hub for lively evenings and memorable moments. Or, head to Al Ventuno for a great selection of flavorful drinks and a charming setting. Furthermore, Avio is perfect for those looking to extend their night with a touch of local flavor.

Head back to your accommodation in Lecce and get some rest to prepare for another magical day of your road trip in Italy.

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Day 4

Day 4

  • Lecce
  • More

Drive 363 km, 4 hours 36 min

  • Belvedere di Piazza Giovanni Pascoli
  • Sassi di Matera
  • Cattedrale di Maria Santissima della Bruna e Sant'Eustachio
  • Palombaro lungo
  • More

On day 4 of your road trip, you'll get the chance to experience Matera. At the end of the day, you'll drive back to Lecce, where you still have 1 night left to stay.

Make a stop at Belvedere Di Piazza Giovanni Pascoli. This intriguing observation deck is a must-visit for travelers looking for a unique holiday experience. Make your way to Sassi Di Matera located in Lecce for another exciting encounter.

Next, immerse yourself in the setting of Cattedrale Di Maria Santissima Della Bruna E Sant'eustachio. Its stunning features will captivate you. After the church, continue your tour of the city with a visit to Palombaro Lungo. Visitors usually appreciate the UNESCO world heritage-listed features of this cave system.

When you’re done exploring for the day, you’ll return to Lecce and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Lecce. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Make sure to reserve a table at L'OSTRICA UBRIACA di viale della Libertà, an iconic dining spot in Lecce. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of L'angolino di Via Matteotti, a popular restaurant in Lecce. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Bar L'Incontro | Caffetteria, Pasticceria, Rosticceria, a hidden gem nestled in Lecce. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

To truly maximize your evening out, consider visiting Quanto Basta after dinner. This bar is known for offering some of the best drinks and vibes in the city.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day 5

Day 5

  • Lecce
  • Naples
  • More

Drive 511 km, 6 hours 47 min

  • Costiera Amalfitana Positano
  • Chiesa di Santa Maria Assunta
  • Viewpoint.8-Amalfi Dr
  • More

On day 5 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, including Positano and Vico Equense. When you’re not sightseeing, take time to relax at your chosen hotel in Naples, where you’ll be staying for 4 nights.

Awaiting your discovery is the frequently visited Costiera Amalfitana Positano, a serene beach in Lecce. Next, go to Chiesa Di Santa Maria Assunta.

After visiting Costiera Amalfitana Positano and Chiesa Di Santa Maria Assunta, have a stroll along Lecce's streets and take in the local charm. Continue your sightseeing by heading to Viewpoint.8-amalfi Dr. This visually striking observation deck offers a unique experience.

At the end of the day, you will drive to Naples, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Naples's best restaurants.

Dine in style at L'Oca Nera Irish Pub, a top recommendation for dinner tonight. Or, for a change of pace, Mimì alla Ferrovia boasts a menu that's sure to impress. Also, be sure to check out Spuzzulè Winebar. Known as a local hotspot, it’s a great choice for tonight in Naples.

Extend your evening after a delightful meal by visiting Happening Cocktail Bar, which offers the perfect atmosphere for a night out. Moreover, Shanti Art Musik Bar is another popular option for a drink or two. Likewise, Gran Caffè Gambrinus also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day 6

Day 6

  • Naples
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Drive 146 km, 4 hours 19 min

  • Amalfi Coast
  • Path of the Lemons
  • Villa Rufolo
  • Villa Cimbrone Gardens
  • Li Cannati - Sentiero degli Dei
  • More

On day 6 of your road trip, you’ll start and end your day in Naples, where you still have 3 nights left. You'll spend part of the day exploring places of interest outside the immediate city, including Amalfi, Minori, Ravello, Castiglione, and Bomerano.

Look forward to a unique sightseeing adventure at the impressive Amalfi Coast and allow yourself time to explore. Just a short distance away you'll find your next stop, Path Of The Lemons, a mesmerizing hiking area that draws visitors from far and near.

Continue your journey to Villa Rufolo, one of the village’s most notable spots that you shouldn’t miss. Another great site to visit is the beloved Villa Cimbrone Gardens. When you're finished at the botanical garden, Li Cannati - Sentiero Degli Dei awaits your visit. This hiking area is a romantic highlight on today's itinerary.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Naples.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Naples. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a delicious meal at Antica Pizzeria Di Matteo, a highly-rated dining destination in Naples. If you're eager to try something different, consider Mercure Napoli Centro Angioino, another top spot with a tantalizing menu. You might also want to secure a reservation at La Lazzara Trattoria e Pizzeria. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Naples this evening.

Extend your evening after a delightful meal by visiting Archivio Storico - Cocktail Bar & Wonderfood, which offers the perfect atmosphere for a night out. Moreover, Archeobar is another popular option for a drink or two. Likewise, Babette Pub also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

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Day 7

Day 7

  • Naples
  • More

Drive 9 km, 1 hour 23 min

  • Naples National Archaeological Museum
  • Cappella Sansevero
  • piazza del Plebiscito
  • Ovo Castle
  • Via Toledo
  • More

Day 7 offers an itinerary packed with the best things to see in Naples. You’ll stay in Naples for 2 nights more, offering you enough time to explore at a relaxed pace.

Via Toledo is one of the highlights of today. Take your time exploring this iconic street in Naples, which offers a perfect blend of history and culture. Plus, it's close to many must-see landmarks in the city.

No visit to Naples is complete without Naples National Archaeological Museum. This popular museum is one of the top attractions in the city. Proceed to Cappella Sansevero, another must-visit attraction.

As you wander through the inviting streets of Naples, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Piazza Del Plebiscito. This widely recognized public square is a traveler-favorite. Not far away, you’ll find Ovo Castle, another key site on your sightseeing itinerary.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Naples's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a delightful dinner at Opera Restaurant, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Trattoria San Ferdinando? It's another excellent option with a diverse menu. Consider reserving a table at Anonymous Trattoria Gourmet as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Naples.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Gran Caffè Cimmino stands out as an excellent choice for a post-dinner cocktail. Alternatively, Flanagan's Bar offers an ideal atmosphere to enjoy the pleasures of the night. Bar Napoli is also a great option that provides a perfect setting for a relaxing evening.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 8

Day 8

  • Naples
  • More

Drive 56 km, 1 hour 41 min

  • Amphitheatre of Pompeii
  • Teatro Grande
  • Lupanar des esclaves
  • House of the Vettii
  • Archaeological Park of Pompeii
  • More

On day 8 of your road trip, you’ll start and end your day in Naples, where you have 1 night left to stay.

Amphitheatre Of Pompeii brings Naples's character to life. This picture-perfect archeological site is a highlight of any visit in the town. Then, enjoy Teatro Grande, another UNESCO world heritage-designated attraction that never fails to captivate visitors. Next, head over to Lupanare Di Pompei, one of the town’s most curiosity-inducing attractions, known for its photogenic features.

If you’re looking for more, spend time soaking in the atmosphere of House Of The Vettii. This photogenic archeological site is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Archaeological Park Of Pompeii, an interesting archeological site, and take a stroll around the area.

When you’re done exploring for the day, you’ll return to Naples and your accommodation.

Indulge in a memorable dining experience at one of Naples's most popular restaurants, and connect with friendly locals for a true cultural experience.

Have a fantastic dining experience at Piazza Sannazaro, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Osteria Il Gobbetto offers an enticing alternative with its varied menu. Additionally, Trattoria Castel Nuovo is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Naples.

Let the evening flow smoothly from dinner to drinks at Parthenope Bar, a top-rated bar in the area. For other recommendations, Gran Caffè Mexico provides a perfect setting for rounding out your night with style and great drinks. Likewise, Novecento Wine Bar offers a memorable night with diverse drink options and excellent service.

Savor another day of unforgettable experiences in Italy!

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Day 9

Day 9

  • Naples
  • Brindisi
  • More

Drive 392 km, 4 hours 41 min

  • CENTRO STORICO
  • Colonna di Sant'Oronzo
  • Castello Dentice di Frasso di Carovigno
  • More

On day 9 of your road trip in Italy, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Ostuni and Carovigno are on today's agenda. In the evening, you’ll end up in Brindisi, where you will stay for 1 night.

Catch Centro Storico before the crowds roll in. This enchanting historical landmark is sure to ignite your curiosity. Next, dive into the picture-perfect features of Guglia Di Sant'oronzo, a must-visit monument in the town.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Castello Dentice Di Frasso Di Carovigno, an increasingly popular castle.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Brindisi. Brindisi offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Brindisi. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a delicious dinner at Betty - Gelateria Cafe Ristorante Pizzeria a Brindisi, an excellent option for tonight's dining. Looking for something different? Bento offers a tantalizing alternative with its diverse menu. And don’t miss Cozza Nera. Known for great service, it’s a fantastic choice for tonight in Brindisi.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 10

Day 10

  • Brindisi - Departure day
  • More
  • Cillarese Park
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Brindisi before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Cillarese Park, an instagrammable park before you head out.

Make the most of your final day in Italy by visiting Brindisi’s iconic markets and shopping establishments. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Brindisi.

If you're in the mood to try something new, consider Pizzeria La Nassa, another top spot with a mouthwatering menu.

You’ll then say farewell to Brindisi. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
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Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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