10-Day Italy Self-Drive Road Trip With Itinerary from Brindisi traveling west to Taranto, Salerno, Rome, Naples, and Bari

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Ostuni white town skyline at sunset, Brindisi, Apulia southern Italy. Europe.
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Escape the ordinary with this exciting 10-day road trip through Italy. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 2 nights in Brindisi, 1 night in Taranto, 1 night in Salerno, 3 nights in Rome, 1 night in Naples, and 1 night in Bari. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Brindisi, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.

As you hit the open road and drive through Brindisi, Fasano, Ostuni, Carovigno, Taranto, Matera, Salerno, Pompei, Rome, Naples, Trani, Bari, Polignano a Mare, and Alberobello, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Day 1

Day 1

  • Brindisi - Arrival day
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  • Colonne Romane
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Say hello to Brindisi! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Brindisi for 1 night before you continue your adventure!

Brindisi is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out End Of The Via Appia Antica, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Brindisi. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Brindisi, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Bracerie Escosazio, a top-rated dining destination in Brindisi. If you're in the mood to try something new, consider Penny, another top spot with a mouthwatering menu. You might also want to secure a reservation at Piadineria. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Brindisi this evening.

After your meal, keep the night alive at a bar like Peddy Bar. Pasticceria. Gelateria. Happyhour. Prodotti Celiaci. Slot Machines. Scommesse, known for its lively atmosphere. Eden Cafè is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Altair Cafè offers an excellent atmosphere for those looking to amp up the evening.

Raise a toast to the start of your 10-day road trip in Italy!

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Day 2

Day 2

  • Brindisi
  • Taranto
  • More

Drive 164 km, 2 hours 18 min

  • Zoosafari Fasanolandia
  • Parco naturale regionale Dune costiere da Torre Canne a Torre S.Leonardo
  • Castello Dentice di Frasso di Carovigno
  • More

Your itinerary for day 2 of your road trip in Italy includes 3 stops and features some of the highlights of Fasano, Ostuni, and Carovigno. At the end of the day, enjoy the comforts of a top-rated hotel in Taranto, where you'll spend 1 night.

No visit to Brindisi is complete without Zoosafari Fasanolandia. This notable safari park is one of the top attractions in the town. Proceed to Parco Naturale Regionale Dune Costiere Da Torre Canne A Torre S. Leonardo, another must-visit attraction.

As you wander through the inviting streets of Brindisi, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Castello Dentice Di Frasso Di Carovigno. This locally appreciated castle is a traveler-favorite.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Taranto. Taranto offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Taranto is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Taranto.

Treat yourself to a wonderful meal at Come Vuoi Pane & Condimenti, a top-rated dining spot in Taranto. If you're in the mood for something new, try Ricci - Pizzaioli dal 1963, another premier location with a delectable menu. You might also want to book a table at Ristorante La Pignata. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Taranto.

Keep the excitement of the evening going by visiting a bar or two. Bar Center is an excellent place to start. You could also check out Tabir, offering a different kind of charm. A last recommendation for the day is Old Fashion. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 3

Day 3

  • Taranto
  • Salerno
  • More

Drive 263 km, 3 hours 31 min

  • Monumento ai caduti
  • Piazza della Vittoria
  • National Archaeological Museum of Taranto-Marta
  • Parco Scultura La Palomba
  • More

Experience an unparalleled adventure on day 3 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Taranto and Matera. At the end of the day, you will retreat to the hotel of your choice in Salerno, where will spend 1 night.

Look forward to a unique sightseeing adventure at the increasingly popular Monumento Ai Caduti and allow yourself time to explore. Just a short distance away you'll find your next stop, Piazza Della Vittoria, a standout public square that draws visitors from far and near.

Continue your journey to National Archaeological Museum Of Taranto-marta, one of the city’s most up-and-coming spots that you shouldn’t miss. Another great site to visit is the up-and-coming Parco Scultura La Palomba.

At the end of the day, you will drive to Salerno, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Salerno's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to an extraordinary dining experience at Re Maurì, a 1-star Michelin restaurant offering an incredible creative menu. Alternatively, if your taste buds call for something different, L'Unico Drink & Food Salerno is another top choice with a popular menu.

Explore the vibrant nightlife at Hilton Bar E Gastronomia after your meal, a hub for lively evenings and memorable moments. Or, head to The Black Monday Speakeasy Tbm for a great selection of flavorful drinks and a charming setting. Furthermore, Dòmo I' Vinaino Wine Bar - Enogastronomia is perfect for those looking to extend their night with a touch of local flavor.

Head back to your accommodation in Salerno and get some rest to prepare for another magical day of your road trip in Italy.

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Day 4

Day 4

  • Salerno
  • Rome
  • More

Drive 282 km, 3 hours 47 min

  • Archaeological Park of Pompeii
  • Basilica
  • Saint Peter's Square
  • St Peter's Basilica
  • More

Dive into day 4 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Pompei and Vatican City. At the end of the day, you’ll unwind at one of the finest accommodations in Rome, where you'll spend 3 nights.

Check out the locally renowned archeological site, Archaeological Park Of Pompeii. Afterward, continue to Basilica, an archeological site every traveler should visit. As you explore Salerno’s charming streets, take in the lively atmosphere and get to know the character of the town.

Next, make your way to Saint Peter's Square. This popular square is an essential stop. Following that, head to St. Peter's Basilica, another must-visit site that will enhance your experience.

When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and relax before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Rome, it's often a good idea to reserve a table in advance.

Prepare for an extraordinary culinary adventure in Rome by booking a table at La Pergola, a 3-star Michelin restaurant that boasts an exceptional mediterranean and contemporary menu. For a different flavor experience, head to Il Pagliaccio, renowned for its delectable creative and innovative dishes. This 2-star Michelin restaurant consistently wows guests, making it a memorable stop during your holiday. Looking for another option? Visit Enoteca La Torre, a local gem known for its delightful mediterranean and creative cuisine in Rome. Nestled in the city's heart, this 2-star Michelin restaurant is a perfect choice for discerning restaurant-goers seeking a new experience.

Extend your evening after a delightful meal by visiting La Botticella Of Poggi Giovanni, which offers the perfect atmosphere for a night out. Moreover, Almalu Trastevere is another popular option for a drink or two. Likewise, Bar Viminale Di Pepi Maurilio also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 5

Day 5

  • Rome
  • More

Drive 4 km, 1 hour 2 min

  • Piazza Navona
  • Pantheon
  • Roman Forum
  • Colosseum
  • Monti
  • More

Day 5 of your road trip will take you to the best attractions Rome has to offer. Cherish the 2 nights you have left in the city and use the provided itinerary to discover what to see in Rome.

A top thing to do today is to explore Monti, a must-see neighborhood in Rome. It's the perfect starting point for touring the top attractions in the area.

Piazza Navona is perfect for a self-paced visit during the day. This visually striking public square is sure to impress. Next on your list is Pantheon, another must-visit landmark and iconic monument renowned for its respected features.

While exploring and sightseeing, take time to savor the culture of Rome by sampling some local delicacies. When you’re ready for more sightseeing, head to Roman Forum. This UNESCO world heritage-listed archeological site is an essential place to visit for anyone looking for the full Rome experience. We also recommend visiting Colosseum, a globally renowned archeological site.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Make sure to reserve a table at RomAntica, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Coso Ristorante, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of DEROMA - Farine Romane, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

To truly maximize your evening out, consider visiting Sant' Eustachio Caffè after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Yellowsquare Rome, another bar with an inviting ambiance. Similarly, Caffè Portofino also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Savor another day of unforgettable experiences in Italy!

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Day 6

Day 6

  • Rome
  • More

Drive 10 km, 49 min

  • Spanish Steps
  • Piazza di Spagna
  • Castel Sant'Angelo
  • Trastevere
  • Via dei Condotti
  • More

Day 6 offers an itinerary packed with the best things to see in Rome. You’ll stay in Rome for 1 night more, offering you enough time to explore at a relaxed pace.

One of the most iconic spots you can visit today is Trastevere. Allow yourself some time to explore this neighborhood and discover its unique quirks. You'll also find many of the best sightseeing spots nearby. You can also explore Via dei Condotti, a street that offers a glimpse into local life and culture.

No visit to Rome is complete without Spanish Steps. This spectacular public square is one of the top attractions in the city. Proceed to Piazza Di Spagna, another must-visit attraction.

As you wander through the inviting streets of Rome, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Castel Sant'angelo. This spectacular castle is a traveler-favorite.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Don’t miss out on dining at Hotel de Russie, a top-rated dining destination in Rome. If you're in the mood to try something new, consider La Taverna Italiana, another top spot with a mouthwatering menu. You might also want to secure a reservation at The Parrot Bar. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

After savoring a delicious meal, step into the vibrant nightlife at The Apartment Bar Roma, where the evening is just getting started. In the same way, Hotel Hassler Roma offers a unique charm perfect for experiencing the local bar scene in Rome.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 7

Day 7

  • Rome
  • Naples
  • More

Drive 231 km, 3 hours 23 min

  • Altare della Patria
  • Trevi Fountain
  • piazza del Popolo
  • Villa Borghese
  • More

On day 7 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Rome. When you’re not sightseeing, take time to relax at your chosen hotel in Naples, where you’ll be staying for 1 night.

Enjoy all that Altare Della Patria has to offer. This is a locally renowned monument you should not miss. Another must-see is Trevi Fountain, a world-famous monument in Rome.

When you’re ready for the next sight, head to Piazza Del Popolo. From there, take a leisurely stroll to Villa Borghese, another of the city’s astonishing attractions.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Naples. Naples offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Naples. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a memorable dining experience in Naples by booking a table at Veritas, a 1-star Michelin restaurant presenting an exceptional campanian and contemporary menu. For a different culinary experience in Naples, Il Comandante shines as one of the top destinations, known for its delicious creative and mediterranean cuisine. This 1-star Michelin-awardee consistently earns high praises, making it a must-visit addition to your holiday experience. If you're looking for an alternative, ARIA is known as a top local spot in Naples for its delicious contemporary and modern cuisine. This 1-star Michelin awardee is a highly recommended choice for an unforgettable meal.

Keep the evening going at Happening Cocktail Bar, a great choice for enjoying the after-dinner hours with a drink. You could also go to Shanti Art Musik Bar, which offers a similarly pleasant setting and great drinks. Another option is Gran Caffè Gambrinus, which provides an inviting environment for unwinding after a busy day out.

Say good night to Naples and look forward to another great day of your road trip in Italy!

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Day 8

Day 8

  • Naples
  • Bari
  • More

Drive 270 km, 3 hours 40 min

  • piazza del Plebiscito
  • San Carlo Theatre
  • Ovo Castle
  • Villa Comunale
  • More

On day 8 of your road trip in Italy, your travel plans include 2 stops at the most scenic, wondrous, and interesting places in the region. Naples and Trani are on today's agenda. In the evening, you’ll end up in Bari, where you will stay for 1 night.

Visiting Piazza Del Plebiscito is always a good idea. This extraordinary public square is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the picture-perfect wonders of San Carlo Theatre, a must-see opera house in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Ovo Castle. This captivating castle offers an enriching experience. For a change of pace, head to Villa Comunale, where you can take in enchanting features. These sights offer a fulfilling end to a perfect day.

At the end of the day, you will drive to Bari, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Bari's best restaurants.

Enjoy a lovely dining experience at Fabulà Bari, a popular restaurant in Bari. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Bari at AncheCinema, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated La Tana del Polpo. It’s yet another ideal choice to enhance your time in Bari tonight.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Noise, a well-loved spot among locals and tourists. Or, head to Luau Tiki Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Mercantilenove, another top-rated place in the area.

Savor another day of unforgettable experiences in Italy!

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Day 9

Day 9

  • Bari
  • Brindisi
  • More

Drive 151 km, 3 hours 4 min

  • Basilica San Nicola
  • Teatro Petruzzelli
  • Lama Monachile
  • Monumento a Domenico Modugno
  • Trulli di Alberobello Puglia
  • More

Your itinerary for day 9 of your road trip in Italy includes 3 stops and features some of the highlights of Bari, Polignano a Mare, and Alberobello. At the end of the day, enjoy the comforts of a top-rated hotel in Brindisi, where you'll spend 1 night.

Basilica Di San Nicola is perfect for a self-paced visit during the day. This standout church is sure to impress. Next on your list is Teatro Petruzzelli, another must-visit landmark and beloved performing arts theater renowned for its historic features.

While exploring and sightseeing, take time to savor the culture of Bari by sampling some local delicacies. When you’re ready for more sightseeing, head to Lama Monachile. This mesmerizing beach is an essential place to visit for anyone looking for the full Bari experience. We also recommend visiting Monumento A Domenico Modugno, an increasingly popular monument. Nearby, you'll also find Trulli Di Alberobello Puglia, ready to add charm to your journey.

When you’re done exploring for the day, you’ll drive to your hotel in Brindisi. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Brindisi. Enjoy a relaxing evening as you savor delicious local cuisine.

Savor the flavors at Betty - Gelateria Cafe Ristorante Pizzeria a Brindisi, a top pick for dinner tonight. Alternatively, Bento beckons with its unique menu offerings. Also, consider Cozza Nera. With its consistent customer satisfaction, it’s an excellent option for dining in Brindisi tonight.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

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Day 10

Day 10

  • Brindisi - Departure day
  • More
  • Swabian Castle of Brindisi
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Brindisi before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Swabian Castle Of Brindisi, a culturally significant castle before you head out.

Make the most of your final day in Italy by visiting Brindisi’s iconic markets and shopping establishments. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Brindisi.

Have a fantastic dining experience at Rendez-Vous Cafè Bistrot, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Pizzeria La Nassa offers an enticing alternative with its varied menu.

You’ll then say farewell to Brindisi. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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