10-Day Sicily Self-Drive Road Trip With Itinerary from Catania to Taormina, Syracuse, Agrigento, and Palermo

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Piazza del Duomo in Catania on a summer day, with Duomo of Saint Agatha and the Elephant Fountain. Sicily, southern Italy. View of Cathedral Sant Agata on Piazza del Duomo in Catania, Sicily, Italy.
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Description

Experience the freedom of the open road on an unforgettable 10-day road trip in Sicily! Embark on a self-drive tour that caters to every traveler, featuring destinations like Catania, Taormina, Linguaglossa, Syracuse, Noto, Ragusa, Agrigento, Villaseta, Palermo, Monreale, and Cefalù.

This perfectly planned road trip itinerary takes you through some of the best places to see in Sicily. You will spend 3 nights in Catania, 2 nights in Taormina, 2 nights in Syracuse, 1 night in Agrigento, and 1 night in Palermo. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Catania, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Valle Dei Templi and Palermo Cathedral are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Catania, Taormina, Linguaglossa, Syracuse, Noto, Ragusa, Agrigento, Villaseta, Palermo, Monreale, and Cefalù, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
Drop-off: 10:00

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Day 1

Day 1

  • Catania - Arrival day
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  • Villa Bellini/Chiosco Bellini
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Welcome to Catania, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 2 nights discovering what to see in Catania before embarking on the next leg of your journey.

Catania is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Catania. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Catania, it's often a good idea to reserve a table in advance.

Raise a toast to the start of your 10-day road trip in Sicily!

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Day 2

Day 2

  • Catania
  • More

Drive 1 km, 24 min

  • Palazzo Platamone
  • Teatro Massimo Bellini
  • Piazza Università
  • Fountain of the Elephant
  • Basilica Cattedrale di Sant'Agata
  • Greek - Roman theatre
  • More

Day 2 offers an itinerary packed with the best things to see in Catania. You’ll stay in Catania for 1 night more, offering you enough time to explore at a relaxed pace.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Sicily. You can explore and select activities under each day of your itinerary.

Catania is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Catania.

Get a good night's sleep and look forward to another great day on the road in Sicily!

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Day 3

Day 3

  • Catania
  • Taormina
  • More

Drive 53 km, 57 min

  • Porta Catania
  • Fontana di Piazza Duomo
  • Basilica of St. Nicholas of Bari
  • More

Dive into day 3 of your remarkable road trip in Sicily. Today you'll explore 1 destination, including Taormina. At the end of the day, you’ll unwind at one of the finest accommodations in Taormina, where you'll spend 2 nights.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Taormina. Taormina offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Taormina's best restaurants.

Savor another day of unforgettable experiences in Sicily!

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Day 4

Day 4

  • Taormina
  • More

Drive 92 km, 2 hours 47 min

  • Piano Provenzana
  • Isola Bella
  • Villa Comunale di Taormina
  • Ancient theatre of Taormina
  • More

Greet day 4 of your road trip in Sicily with a smile and start your day with a hearty breakfast. You have 1 night to stay in Taormina, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Linguaglossa, Mazzarò, and Taormina.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Taormina.

Taormina is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Taormina.

Head back to your accommodation in Taormina and get some rest to prepare for another magical day of your road trip in Sicily.

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Day 5

Day 5

  • Taormina
  • Syracuse
  • More

Drive 122 km, 1 hour 49 min

  • Ear of Dionysius
  • Neapolis Archaeological Park
  • Cathedral of Syracuse
  • Island of Ortigia
  • Fountain of Diana
  • Temple of Apollo
  • More

On day 5 of your road trip in Sicily, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Syracuse are on today's agenda. In the evening, you’ll end up in Syracuse, where you will stay for 2 nights.

When you’re done exploring for the day, you’ll drive to your hotel in Syracuse. Check in and relax before you head out to tour the city.

Syracuse is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Syracuse.

Relax and look forward to more memorable moments to come!

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Day 6

Day 6

  • Syracuse
  • More

Drive 191 km, 2 hours 57 min

  • Porta Reale o Ferdinandea
  • Roman Catholic Diocese of Noto
  • Palazzo Landolina
  • Nicolaci Palace
  • Duomo di San Giorgio
  • More

Wake up to day 6 of your road trip in Sicily. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Noto and Ragusa. With 1 night to stay in Syracuse, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

When you’re done exploring for the day, you’ll return to Syracuse and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Syracuse. Enjoy a relaxing evening as you savor delicious local cuisine.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Sicily.

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Day 7

Day 7

  • Syracuse
  • Agrigento
  • More

Drive 220 km, 3 hours 9 min

  • Museo archeologico regionale Pietro Griffo
  • Valle dei Templi
  • Temple of Heracles
  • Tempio Di Zeus Olympios
  • Kolymbetra
  • More

On day 7 of your exciting self-drive vacation in Sicily, you’ll soak in the magnificence of 2 destinations, including Agrigento and Villaseta. When you’re not sightseeing, take time to relax at your chosen hotel in Agrigento, where you’ll be staying for 1 night.

At the end of the day, you will drive to Agrigento, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Agrigento, it's often a good idea to reserve a table in advance.

Say good night to Agrigento and look forward to another great day of your road trip in Sicily!

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Day 8

Day 8

  • Agrigento
  • Palermo
  • More

Drive 133 km, 2 hours 42 min

  • Foro Italico
  • Fontana Pretoria
  • Quattro Canti
  • Palermo Cathedral
  • Norman Palace
  • Catacombe dei Cappuccini
  • More

Experience an unparalleled adventure on day 8 of your road trip in Sicily. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Palermo. At the end of the day, you will retreat to the hotel of your choice in Palermo, where will spend 1 night.

Throughout the day, make sure to take breaks to appreciate the surroundings.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Palermo. Palermo offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Palermo's most popular restaurants, and connect with friendly locals for a true cultural experience.

Raise your glass and celebrate another amazing day of your road trip in Sicily!

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Day 9

Day 9

  • Palermo
  • Catania
  • More

Drive 282 km, 4 hours 35 min

  • Cattedrale di Monreale
  • Chiostro Benedettino
  • Rocca di Cefalù
  • Cathedral of Cefalù
  • Lavatoio Medievale Fiume Cefalino - Cefalù (pa)
  • Porta della Pescara (Porta Marina)
  • More

Your itinerary for day 9 of your road trip in Sicily includes 2 stops and features some of the highlights of Monreale and Cefalù. At the end of the day, enjoy the comforts of a top-rated hotel in Catania, where you'll spend 1 night.

When you’re done exploring for the day, you’ll drive to your hotel in Catania. Check in and relax before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Catania. Enjoy a relaxing evening as you savor delicious local cuisine.

Raise your glass to another unforgettable day in Sicily!

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Day 10

Day 10

  • Catania - Departure day
  • More
  • Castello Ursino
  • More

Day 10 of your road trip in Sicily is your departure day. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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How it works

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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Your trip is protected, personalized, and priced right. No surprises, no stress.

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