10-Day Sicily Self-Drive Road Trip With Itinerary from Catania to Taormina, Syracuse, Agrigento, and Palermo

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Piazza del Duomo in Catania on a summer day, with Duomo of Saint Agatha and the Elephant Fountain. Sicily, southern Italy. View of Cathedral Sant Agata on Piazza del Duomo in Catania, Sicily, Italy.
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Explore the best of Sicily on a 10-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Catania, Taormina, Linguaglossa, Syracuse, Noto, Ragusa, Agrigento, Villaseta, Palermo, Monreale, and Cefalù. This road trip itinerary in Sicily seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Sicily takes you through some of the best places to see in the country. You will spend 3 nights in Catania, 2 nights in Taormina, 2 nights in Syracuse, 1 night in Agrigento, and 1 night in Palermo. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Catania, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Valle Dei Templi and Palermo Cathedral are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Ancient Theatre Of Taormina, learn more about the unique Cattedrale Di Monreale, and immerse yourself in the vibrant atmosphere of Quattro Canti.

As you hit the open road and drive through Catania, Taormina, Linguaglossa, Syracuse, Noto, Ragusa, Agrigento, Villaseta, Palermo, Monreale, and Cefalù, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Day 1

Day 1

  • Catania - Arrival day
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  • Villa Bellini/Chiosco Bellini
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Your road trip adventure in Sicily begins as soon as you reach Catania and pick up your car. You’ll stay in Catania for 2 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Catania is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Giardino Bellini, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Catania. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Catania, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Ristorante da Antonio, a top-rated dining spot in Catania. If you're in the mood for something new, try Lido Arcobaleno, another premier location with a delectable menu. You might also want to book a table at Lido Azzurro. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Catania.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Caffè Europa stands out as an excellent choice for a post-dinner cocktail. Alternatively, Insigne Cafè offers an ideal atmosphere to enjoy the pleasures of the night. Bohéme Mixology Bar is also a great option that provides a perfect setting for a relaxing evening.

Raise a toast to the start of your 10-day road trip in Sicily!

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Day 2

Day 2

  • Catania
  • More

Drive 1 km, 24 min

  • Palazzo Platamone
  • Teatro Massimo Bellini
  • Piazza Università
  • Fountain of the Elephant
  • Basilica Cattedrale di Sant'Agata
  • Greek - Roman theatre
  • More

Day 2 of your road trip will take you to the best attractions Catania has to offer. Cherish the 1 night you have left in Catania by discovering the best things there are to see and do in the city.

Set out on a day brimming with fun adventures, picturesque spots, and history-rich sites. Start at the locally appreciated Palazzo Platamone, a photogenic palace in Catania. Next, go to Teatro Massimo Bellini.

After visiting Palazzo Platamone and Teatro Massimo Bellini, have a stroll along Catania's streets and take in the local charm. Continue your sightseeing by heading to Piazza Università. This history-steeped public square offers a unique experience. Elephant Fountain is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Catania Cathedral, one of the most enchanting places to visit in Catania. If you still have some time left for sightseeing, we also recommend stopping by Roman Theatre Of Catania.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Sicily is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Catania. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a wonderful meal at Il Gambero Pazzo, a top-rated dining spot in Catania. If you're in the mood for something new, try Deliziosa, another premier location with a delectable menu. You might also want to book a table at Lettera 82 Risto Pub. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Catania.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Circus Cocktail Bar, known for its inviting atmosphere. Caffè Opera is another great option if you’re looking for a place to get the night started. Similarly, Chiosco Sicilia Seltz provides a great setting to enjoy the night away.

Savor another day of unforgettable experiences in Sicily!

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Day 3

Day 3

  • Catania
  • Taormina
  • More

Drive 53 km, 57 min

  • Porta Catania
  • Fontana di Piazza Duomo
  • Basilica of St. Nicholas of Bari
  • More

On day 3 of your road trip in Sicily, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Taormina. In the evening, you’ll end up in Taormina, where you will stay for 2 nights.

Catania is home to plenty of attractions that offer fun adventures, photo-friendly spots, and history-rich sites! Start at Porta Catania, an increasingly popular monument that is worthwhile a visit in the town. Nearby, you’ll find Fontana Di Piazza Duomo, enchanting visitors with its history-steeped appeal. Continue your exploration at Basilica Of St. Nicholas Of Bari. This church is one of the town’s most up-and-coming spots.

At the end of the day, you will drive to Taormina, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Taormina's best restaurants.

Enjoy a delicious meal at PizzaMania Taormina, a top-rated dining destination in Taormina. If you're in the mood to try something new, consider Ristorante Pizzeria Tiramisù Taormina, another top spot with a mouthwatering menu. You might also want to secure a reservation at La Pignolata Guinness Cannoli Taormina since 1978 N°15. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Taormina this evening.

Keep the evening going at Luraleo Bar, a great choice for enjoying the after-dinner hours with a drink. You could also go to Don Diego Gelateria Caffetteria, which offers a similarly pleasant setting and great drinks.

Raise your glass to another unforgettable day in Sicily!

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Day 4

Day 4

  • Taormina
  • More

Drive 92 km, 2 hours 47 min

  • Piano Provenzana
  • Isola Bella
  • Villa Comunale di Taormina
  • Ancient theatre of Taormina
  • More

On day 4 of your road trip, you’ll start and end your day in Taormina, but spend part of the day exploring places of interest outside the immediate town. On today's itinerary, you'll find attractions in Linguaglossa, Mazzarò, and Taormina. You still have 1 night left in Taormina.

Start your adventure at Piano Provenzana. This up-and-coming ski resort is a must-visit for travelers looking for a unique holiday experience. Make your way to Isola Bella located in Taormina for another exciting encounter.

Next, immerse yourself in the setting of Villa Comunale Di Taormina. Its romantic features will captivate you. After the park, continue your tour of the city with a visit to Ancient Theatre Of Taormina. Visitors usually appreciate the romantic features of this archeological site.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Taormina.

As you explore more of Taormina, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Make sure to reserve a table at Osteria Il Vicoletto, an iconic dining spot in Taormina. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Tischi Toschi Taormina, a popular restaurant in Taormina. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Siciliano Taormina Osteria Pizzeria, a hidden gem nestled in Taormina. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Relax and reminisce about your day in Sicily and look forward to more memorable moments to come!

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Day 5

Day 5

  • Taormina
  • Syracuse
  • More

Drive 122 km, 1 hour 49 min

  • Ear of Dionysius
  • Neapolis Archaeological Park
  • Cathedral of Syracuse
  • Island of Ortigia
  • Fountain of Diana
  • Temple of Apollo
  • More

Experience an unparalleled adventure on day 5 of your road trip in Sicily. This exciting part of your journey invites you to discover the renowned landmarks in 1 vibrant destinations - Syracuse. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in Syracuse. You will spend 2 nights here for some well-deserved relaxation.

Today’s agenda in Taormina includes a cave, an archeological site, a church, a historical landmark, a monument and much more! Ear Of Dionysius is must-visit cave and a great starting point for the day. Next, continue your journey to Neapolis Archaeological Park, a popular archeological site, located just a leisurely stroll away. Next, head to Cathedral Of Syracuse, a romantic church, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Taormina. When you're ready, let your sightseeing route take you to the frequently visited Ortygia. If you’re looking for more, Diana Fountain is also a curiosity-inducing attraction that is worthwhile a visit. Lastly, don’t miss Temple Of Apollo, a place of culturally significant interest in the city.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Syracuse. Syracuse offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you explore more of Syracuse, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Treat yourself to a delightful dinner at A Putia, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Dock Café Restaurant? It's another excellent option with a diverse menu. Consider reserving a table at Olivia Natural Bistrot | Pizzeria, Ristorante vegetariano - vegano as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Syracuse.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Barcollo, a well-loved spot among locals and tourists. Or, head to Bar Pasticceria Midolo. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Boats, another top-rated place in the area.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Sicily.

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Day 6

Day 6

  • Syracuse
  • More

Drive 191 km, 2 hours 57 min

  • Porta Reale o Ferdinandea
  • Roman Catholic Diocese of Noto
  • Palazzo Landolina
  • Nicolaci Palace
  • Duomo di San Giorgio
  • More

At the end of the day, you'll drive back to Syracuse, where you'll stay for 1 night more.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Syracuse allows for both. Start by heading to Porta Reale O Ferdinandea. This beloved monument provides an insightful glimpse into the town's identity. Next, discover Roman Catholic Diocese Of Noto, a heritage-rich church, promising a delightful encounter.

Continue your sightseeing with a visit to Palazzo Landolina, a curiosity-inducing palace. When you’re done, don’t forget to make a stop at the curiosity-inducing Nicolaci Palace. Round off your day at Duomo Of San Giorgio, another gem in Syracuse with visually striking features to discover.

When you’re done exploring for the day, you’ll return to Syracuse and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat in Syracuse. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Dine in style at La Lisca Cucina e Bottega, a top recommendation for dinner tonight. Or, for a change of pace, SICULISH HERE AND NOW boasts a menu that's sure to impress. Also, be sure to check out Ammucca - Sicilian Quality Meat Food. Known as a local hotspot, it’s a great choice for tonight in Syracuse.

After enjoying a fulfilling meal, continue your evening at Bar Tunisi, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Verga Courtyard - Cafeteria offers a welcoming atmosphere for easing into the nightlife. Similarly, Glam Café provides an excellent environment for a relaxed and enjoyable evening.

Celebrate another amazing day of your road trip adventure in Sicily!

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Day 7

Day 7

  • Syracuse
  • Agrigento
  • More

Drive 220 km, 3 hours 9 min

  • Museo archeologico regionale Pietro Griffo
  • Valle dei Templi
  • Temple of Heracles
  • Tempio Di Zeus Olympios
  • Kolymbetra
  • More

Embark on another extraordinary experience on day 7 of your road trip in Sicily. Today, you will make 2 stops and experience some of the highlights of Agrigento and Villaseta. At the end of the day, you will enjoy the comforts of a top-rated hotel in Agrigento, which will be your home away from home for 1 night.

Begin your adventure at Archaeological Museum "pietro Griffo" Of Agrigento. This is a beloved museum you should not miss. Another must-see is Valle Dei Templi, a locally renowned archeological site in Syracuse.

When you’re ready for the next sight, head to Temple Of Heracles. From there, take a leisurely stroll to Temple Of Olympian Zeus, another of the city’s worthwhile attractions. We recommend continuing your self-guided tour at Kolymbetra, an eye-catching place of interest in the city.

When you’re done exploring for the day, you’ll drive to your hotel in Agrigento. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Agrigento. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Make sure to reserve a table at Ambasciata di Sicilia, an iconic dining spot in Agrigento. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Le Cuspidi, a popular restaurant in Agrigento. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Yellove RistoVintage, a hidden gem nestled in Agrigento. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Say good night to Agrigento and look forward to another great day of your road trip in Sicily!

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Day 8

Day 8

  • Agrigento
  • Palermo
  • More

Drive 133 km, 2 hours 42 min

  • Foro Italico
  • Fontana Pretoria
  • Quattro Canti
  • Palermo Cathedral
  • Norman Palace
  • Catacombe dei Cappuccini
  • More

Dive into day 8 of your remarkable road trip in Sicily. Today you will explore Palermo, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Palermo. You’ll stay here for 1 night.

Today’s itinerary in Agrigento covers several incredible sights, including a park, a monument, a public square, a church, a palace, a cemetery and much more! Start your adventure at Foro Italico. This up-and-coming park is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the detailed wonders of Fontana Pretoria, a must-see monument in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Quattro Canti. This popular public square offers an enriching experience. For a change of pace, head to Palermo Cathedral, where you can take in breathtaking features. Conclude your self-guided sightseeing tour with a visit to Norman Palace and Catacombe Dei Cappuccini. These sights offer a fulfilling end to a perfect day.

At the end of the day, you will drive to Palermo, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Palermo. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a wonderful meal at Cotto e Bollito, a top-rated dining spot in Palermo. If you're in the mood for something new, try Bebop, another premier location with a delectable menu. You might also want to book a table at Eremiti Restaurant. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Palermo.

Continue your evening by exploring the vibrant nightlife scene at Malox Cult, a prime destination for a thrilling night out. Also, don’t forget to check out Ai Giudici, a bar that offers unique local touches. Likewise, Bar Italico provides an excellent alternative for a fun evening.

Get a good night's sleep and look forward to another great day on the road in Sicily!

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Day 9

Day 9

  • Palermo
  • Catania
  • More

Drive 282 km, 4 hours 35 min

  • Cattedrale di Monreale
  • Chiostro Benedettino
  • Rocca di Cefalù
  • Cathedral of Cefalù
  • Lavatoio Medievale Fiume Cefalino - Cefalù (pa)
  • Porta della Pescara (Porta Marina)
  • More

On day 9 of your exciting self-drive vacation in Sicily, you’ll soak in the magnificence of 2 destinations, Monreale and Cefalù. When you’re not sightseeing, take time to relax at your selected hotel in Catania, where you’ll be staying for 1 night.

Start by visiting Cattedrale Di Monreale, a prime spot to begin your journey. This picture-perfect church is sure to impress. Next on your list is Chiostro Dei Benedettini, another must-visit landmark and beloved monastery renowned for its symbolic features.

While exploring and sightseeing, take time to savor the culture of Palermo by sampling some local delicacies. When you’re ready for more sightseeing, head to Rocca Di Cefalù. This respected castle is an essential place to visit for anyone looking for the full Palermo experience. We also recommend visiting Cefalù Cathedral, a locally renowned church. Nearby, you'll also find Lavatoio Medievale Fiume Cefalino - Cefalù (pa), ready to add charm to your journey. End your self-guided sightseeing tour with a stop at Porta Pescara (porta Marina) and wrap up your day with its romantic appeal.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Catania. Catania offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Catania's most popular restaurants, and connect with friendly locals for an authentic adventure.

Enjoy a lovely meal at A Putia Dell'Ostello, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Carlito's is another top choice with a popular menu. You could also check for a table at La Pentolaccia. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Catania tonight.

Continue the enjoyment post-dinner at Bar Castello, a cherished local gathering spot renowned for its welcoming atmosphere. Similarly, Collage Boutique Bar offers a vibrant space for indulging in well-crafted drinks and engaging conversation.

Take some time to reflect on your day and savor another beautiful night in Sicily.

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Day 10

Day 10

  • Catania - Departure day
  • More
  • Castello Ursino
  • More

Day 10 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Catania before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Castello Ursino. This locally renowned castle is a popular place to see in the city.

Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Catania.

You’ll then say farewell to Catania. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

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With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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