10-Day Sicily Self-Drive Road Trip With Itinerary from Palermo to Agrigento, Ragusa, Syracuse, Catania, Taormina, and Cefalù

1 / 81
Photo of Palermo, Sicily, Italy. Seafront view.
Perfect travel plans
Everything included
Fully customizable

Description

Included

Flights
Select dates
Hotel
Select dates
Car rental
Select dates
Tours & tickets
Select dates
Travel plan
From A to Z
Travel agent
24/7 fast service

Description

Escape the ordinary with this exciting 10-day road trip through Sicily. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Sicily. You will spend 3 nights in Palermo, 1 night in Agrigento, 1 night in Ragusa, 1 night in Syracuse, 1 night in Catania, 1 night in Taormina, and 1 night in Cefalù. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Palermo, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Valle Dei Templi and Palermo Cathedral are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Ancient Theatre Of Taormina, learn more about the unique Quattro Canti, and immerse yourself in the vibrant atmosphere of Norman Palace.

As you hit the open road and drive through Palermo, Agrigento, Villaseta, Ragusa, Syracuse, Catania, Taormina, Cefalù, San Mauro Castelverde, Castelbuono, and Petralia Sottana, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

Read more

Travel details

Set your travel details to find the best price

Flights

Round trip
Round trip
Travel dates

Travelers

Rooms

Flights

Compare and choose from the best flights to Palermo, landing in Palermo

Car

Choose from the best car rental deals or see all options

Driver’s age is 30 - 65
I live in
Pick-up: 10:00
Drop-off: 10:00

Personalize your itinerary

Customize tours under each day and destination

Day 1

Day 1

  • Palermo - Arrival day
  • More
  • Foro Italico
  • More

Say hello to Palermo! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Palermo for 2 nights before you continue your adventure!

Palermo is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Foro Italico, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Palermo. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Cotto e Bollito, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Bebop is another top choice with a popular menu. You could also check for a table at Eremiti Restaurant. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Palermo tonight.

Following your dinner, dive into the local bar culture at Malox Cult. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Ai Giudici, the perfect place for those looking to experience the best of the nightlife. Similarly, Bar Italico provides excellent drinks and a great atmosphere, ensuring a memorable night out.

Raise a toast to the start of your 10-day road trip in Sicily!

Read more
Day 2

Day 2

  • Palermo
  • More

Drive 31 km, 1 hour 38 min

  • Norman Palace
  • Palermo Cathedral
  • Quattro Canti
  • Fontana Pretoria
  • Orto botanico di Palermo
  • Santuario di Santa Rosalia, Palermo
  • More

Day 2 offers an itinerary packed with the best things to see in Palermo. You’ll stay in Palermo for 1 night more, offering you enough time to explore at a relaxed pace.

Norman Palace leaves a lasting impression. This palace is one of the most notable places to visit in Palermo. Next, head to Palermo Cathedral, an interesting church, known for its culturally significant features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Quattro Canti. This symbolic public square is a highly recommended experience. Nearby, you'll also find Fontana Pretoria and Orto Botanico Di Palermo. Visit these for an interesting touch to your journey. Finish the day with a visit to Santuario Di Santa Rosalia, Palermo, a breathtaking church in Palermo.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Sicily. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Palermo. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a delicious meal at Osteria Mercede, a top-rated dining destination in Palermo. If you're in the mood to try something new, consider Trattoria Del Massimo, another top spot with a mouthwatering menu. You might also want to secure a reservation at Grand Hotel Piazza Borsa. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Palermo this evening.

Explore the vibrant nightlife at Spina Bar Palermo after your meal, a hub for lively evenings and memorable moments. Or, head to Torrefazione Castagnetta Massimiliano (gelateria) for a great selection of flavorful drinks and a charming setting. Furthermore, Monkey Pub is perfect for those looking to extend their night with a touch of local flavor.

Take some time to reflect on your day and savor another beautiful night in Sicily.

Read more
Day 3

Day 3

  • Palermo
  • Agrigento
  • More

Drive 162 km, 3 hours 1 min

  • Museo archeologico regionale Pietro Griffo
  • Valle dei Templi
  • Temple of Heracles
  • Casa Natale di Luigi Pirandello e Tomba
  • Scala dei Turchi
  • More

Dive into day 3 of your remarkable road trip in Sicily. Today you'll explore 3 destinations, including Agrigento, Villaseta, and Scavuzzo. At the end of the day, you’ll unwind at one of the finest accommodations in Agrigento, where you'll spend 1 night.

Whatever your travel style is, Archaeological Museum "pietro Griffo" Of Agrigento is an essential stop in Palermo. This beloved museum provides an insightful glimpse into the city's identity. Next, discover Valle Dei Templi, a stunning archeological site, promising a delightful encounter.

Continue your sightseeing with a visit to Temple Of Heracles, a frequently visited archeological site. When you’re done, don’t forget to make a stop at the increasingly popular Casa Natale Di Luigi Pirandello E Tomba. Round off your day at Scala Dei Turchi, another gem in Palermo with majestic features to discover.

At the end of the day, you will drive to Agrigento, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Agrigento. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely dining experience at Ambasciata di Sicilia, a popular restaurant in Agrigento. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Agrigento at Le Cuspidi, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Yellove RistoVintage. It’s yet another ideal choice to enhance your time in Agrigento tonight.

Celebrate another amazing day of your road trip adventure in Sicily!

Read more
Day 4

Day 4

  • Agrigento
  • Ragusa
  • More

Drive 146 km, 3 hours 26 min

  • Giardino Ibleo
  • Portale di San Giorgio
  • Duomo di San Giorgio
  • Cattedrale di San Giovanni Battista
  • excape Ragusa - Escape Room
  • More

On day 4 of your road trip in Sicily, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Ragusa are on today's agenda. In the evening, you’ll end up in Ragusa, where you will stay for 1 night.

Giardino Ibleo is an ideal stop early in the day. This locally appreciated botanical garden is a must-visit in the city. When you’re ready for your next discovery, continue to Portale Di San Giorgio, which may be one of the most history-steeped places you will experience today.

One of the best things about exploring Agrigento on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Duomo Of San Giorgio, an underrated church in the city. If you’re up for more discoveries, don’t forget to reserve some time for Ragusa Cathedral and Excape Ragusa - Escape Room.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Ragusa. Ragusa offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Ragusa, it's often a good idea to reserve a table in advance.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Sicily.

Read more
Day 5

Day 5

  • Ragusa
  • Syracuse
  • More

Drive 98 km, 1 hour 34 min

  • Neapolis Archaeological Park
  • Ear of Dionysius
  • Cathedral of Syracuse
  • Island of Ortigia
  • Fountain of Diana
  • Temple of Apollo
  • More

Experience an unparalleled adventure on day 5 of your road trip in Sicily. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Syracuse. At the end of the day, you will retreat to the hotel of your choice in Syracuse, where will spend 1 night.

Neapolis Archaeological Park leaves a lasting impression. This archeological site is one of the most notable places to visit in Ragusa. Next, head to Ear Of Dionysius, a beloved cave, known for its history-steeped features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Cathedral Of Syracuse. This inviting church is a highly recommended experience. Nearby, you'll also find Ortygia and Diana Fountain. Visit these for an interesting touch to your journey. Finish the day with a visit to Temple Of Apollo, a breathtaking archeological site in Ragusa.

When you’re done exploring for the day, you’ll drive to your hotel in Syracuse. Check in and relax before you head out to tour the city.

After a day of adventure, treat yourself to an exquisite dinner at one of Syracuse's best restaurants.

Dine in style at A Putia, a top recommendation for dinner tonight. Or, for a change of pace, Dock Café Restaurant boasts a menu that's sure to impress. Also, be sure to check out Olivia Natural Bistrot | Pizzeria, Ristorante vegetariano - vegano. Known as a local hotspot, it’s a great choice for tonight in Syracuse.

Continue your evening by exploring the vibrant nightlife scene at Barcollo, a prime destination for a thrilling night out. Also, don’t forget to check out Bar Pasticceria Midolo, a bar that offers unique local touches. Likewise, Boats provides an excellent alternative for a fun evening.

Relax and recharge in preparation for another adventurous day in Sicily!

Read more
Day 6

Day 6

  • Syracuse
  • Catania
  • More

Drive 69 km, 1 hour 30 min

  • Castello Ursino
  • Greek - Roman theatre
  • Villa Bellini/Chiosco Bellini
  • Piazza Università
  • Fountain of the Elephant
  • Basilica Cattedrale di Sant'Agata
  • More

On day 6 of your exciting self-drive vacation in Sicily, you’ll soak in the magnificence of 1 destination, including Catania. When you’re not sightseeing, take time to relax at your chosen hotel in Catania, where you’ll be staying for 1 night.

To truly experience Syracuse, make sure to drop by Castello Ursino. This interesting castle is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Roman Theatre Of Catania, one of the city’s best highlights.

Next, check out Giardino Bellini, one of the most notable places to see in Syracuse. This park is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Piazza Università. Wander around and soak in the stunning atmosphere this public square offers. Then, head to Elephant Fountain, a top-rated monument that adds another dimension to your day. Finally, visit the underrated Catania Cathedral, the last of our attraction recommendations for today.

At the end of the day, you will drive to Catania, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Catania is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Catania.

Enjoy a delicious meal at Ristorante da Antonio, a highly-rated dining destination in Catania. If you're eager to try something different, consider Lido Arcobaleno, another top spot with a tantalizing menu. You might also want to secure a reservation at Lido Azzurro. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Catania this evening.

Continue your lively evening at Caffè Europa, a perfect place for winding down or revving up the night, depending on which mood you’re in. Insigne Cafè is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Bohéme Mixology Bar ensures a night out tailored to your taste.

Head back to your accommodation in Catania and get some rest to prepare for another magical day of your road trip in Sicily.

Read more
Day 7

Day 7

  • Catania
  • Taormina
  • More

Drive 56 km, 2 hours 12 min

  • Isola Bella
  • Villa Comunale di Taormina
  • Ancient theatre of Taormina
  • Chiesa Madonna della Rocca
  • Porta Catania
  • Basilica of St. Nicholas of Bari
  • More

Your itinerary for day 7 of your road trip in Sicily includes 2 stops and features some of the highlights of Mazzarò and Taormina. At the end of the day, enjoy the comforts of a top-rated hotel in Taormina, where you'll spend 1 night.

Isola Bella is must-visit park and a great option for a daytime tour of the area. Continue your journey to Villa Comunale Di Taormina, a curiosity-inducing park, located just a leisurely stroll away. Next, head to Ancient Theatre Of Taormina, a romantic archeological site, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Catania. When you're ready, let your sightseeing route take you to the underrated Chiesa Madonna Della Rocca. If you’re looking for more, Porta Catania is also an intriguing attraction that is worthwhile a visit. Lastly, don’t miss Basilica Of St. Nicholas Of Bari, a place of enchanting interest in the hamlet.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Taormina. Taormina offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Taormina's most popular restaurants, and connect with friendly locals for a true cultural experience.

Don’t miss out on dining at PizzaMania Taormina, a top-rated dining destination in Taormina. If you're in the mood to try something new, consider Ristorante Pizzeria Tiramisù Taormina, another top spot with a mouthwatering menu. You might also want to secure a reservation at La Pignolata Guinness Cannoli Taormina since 1978 N°15. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Taormina this evening.

Explore the vibrant nightlife at Luraleo Bar after your meal, a hub for lively evenings and memorable moments. Or, head to Don Diego Gelateria Caffetteria for a great selection of flavorful drinks and a charming setting.

Get a good night's sleep and look forward to another great day on the road in Sicily!

Read more
Day 8

Day 8

  • Taormina
  • Cefalù
  • More

Drive 212 km, 3 hours 14 min

  • Rocca di Cefalù
  • Cathedral of Cefalù
  • Bastione di Capo Marchiafava
  • Porta della Pescara (Porta Marina)
  • Lavatoio Medievale Fiume Cefalino - Cefalù (pa)
  • Cefalù Beach
  • More

Dive into day 8 of your remarkable road trip in Sicily. Today you'll explore 1 destination, including Cefalù. At the end of the day, you’ll unwind at one of the finest accommodations in Cefalù, where you'll spend 1 night.

One of the most frequently visited attractions included on the itinerary is Rocca Di Cefalù. This enchanting castle will help you start your sightseeing on top. Then, take a leisurely stroll to Cefalù Cathedral and learn what makes this visually striking church unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the intriguing Bastione Di Capo Marchiafava. After exploring the monument, head to Porta Pescara (porta Marina). This locally appreciated historical landmark is a highlight in Taormina. As your day continues, stop by Lavatoio Medievale Fiume Cefalino - Cefalù (pa), known for its history-steeped features. Lastly, don’t forget to check out the worthwhile Spiaggia Di Cefalù. Enjoy exploring this incredible beach at your own pace.

When you’re done exploring for the day, you’ll drive to your hotel in Cefalù. Check in and relax before you head out to tour the town.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Cefalù. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a delightful dinner at Hotel Le Calette, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Ristorante La Brace Cefalù? It's another excellent option with a diverse menu. Consider reserving a table at Sicilian Food & Drink as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Cefalù.

Extend your evening after a delightful meal by visiting Emme Café, which offers the perfect atmosphere for a night out.

Relax and look forward to more memorable moments to come!

Read more
Day 9

Day 9

  • Cefalù
  • Palermo
  • More

Drive 184 km, 3 hours 53 min

  • Gole di Tiberio
  • Parco delle Rimembranze
  • Parco delle Madonie
  • More

On day 9 of your road trip in Sicily, your travel plans include 3 stops at the most scenic, wondrous, and interesting places in the region. San Mauro Castelverde, Castelbuono, and Petralia Sottana are on today's agenda. In the evening, you’ll end up in Palermo, where you will stay for 1 night.

Your adventure in Cefalù is only getting started when you visit Gole Di Tiberio, an increasingly popular local hot spot. Another notable attraction to explore is Parco Delle Rimembranze. This curiosity-inducing park is known for its eye-catching appeal.

After soaking in the highlights of these sights, take some time to wander Cefalù's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Parco Delle Madonie. This mesmerizing national park offers a fascinating experience that many visitors find memorable.

At the end of the day, you will drive to Palermo, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Palermo. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a wonderful meal at Splendid Hotel la Torre, a top-rated dining spot in Palermo. If you're in the mood for something new, try Ristorantino Sobremesa, another premier location with a delectable menu. You might also want to book a table at Ristorante Quattro mani. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Palermo.

To truly maximize your evening out, consider visiting Bar Touring after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Palermo Football Store, another bar with an inviting ambiance. Similarly, Goccio - L’arte Del Miscelare also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Take some time to reflect on your day and savor another beautiful night in Sicily.

Read more
Day 10

Day 10

  • Palermo - Departure day
  • More
  • Catacombe dei Cappuccini
  • More

Day 10 of your road trip in Sicily is your departure day. This is your chance to catch a last glimpse of Palermo before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Catacombe Dei Cappuccini. This notable cemetery is a hotspot among locals.

Take advantage of your accommodation's proximity to Palermo’s shopping district for some last-minute bargain hunting. Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.

Before you conclude your road trip in Sicily, drop by another restaurant for a last chance at a memorable dining experience in Palermo.

You’ll then say farewell to Palermo. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

Read more

How it works

Book your journey with Europe’s biggest travel platform—expert itineraries, instant confirmation, and full flexibility with 24/7 support.

Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

Similar travel packages

Discover other popular vacations in Italy

Link to appstore phone
Install Europe’s biggest travel app

Download Europe’s biggest travel marketplace to your phone to manage your entire trip in one place

Scan this QR code with your phone camera and press the link that appears to add Europe’s biggest travel marketplace into your pocket. Enter your phone number or email address to receive an SMS or email with the download link.