Travel packages in Italy

Road trips in Italy

10-Day Sicily Self-Drive Road Trip With Itinerary from Palermo to Agrigento, Ragusa, Syracuse, Catania, Taormina, and Cefalù

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Photo of Palermo, Sicily, Italy. Seafront view.

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Escape the ordinary with this exciting 10-day road trip through Sicily. Explore diverse landscapes, discover lively cities, and prepare for an unforgettable journey!

This perfectly planned road trip itinerary takes you through some of the best places to see in Sicily. You will spend 3 nights in Palermo, 1 night in Agrigento, 1 night in Ragusa, 1 night in Syracuse, 1 night in Catania, 1 night in Taormina, and 1 night in Cefalù. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Sicily. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Palermo, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Sicily on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Sicily. Valle Dei Templi and Palermo Cathedral are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Palermo, Agrigento, Villaseta, Ragusa, Syracuse, Catania, Taormina, Cefalù, San Mauro Castelverde, Castelbuono, and Petralia Sottana, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Sicily. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Sicily.

Throughout your road trip in Sicily, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Sicily.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Sicily fill up quickly, so book your spot early. Select a date and start planning your road trip in Sicily today!

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Driver’s age is 30 - 65

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Day 1

Palermo - Arrival day
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Foro Italico
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Your road trip adventure in Sicily begins as soon as you reach Palermo and pick up your car. You’ll stay here for 2 nights and explore what to see in Palermo, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Palermo is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Palermo. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Palermo, it's often a good idea to reserve a table in advance.

Raise a toast to the start of your 10-day road trip in Sicily!

Day 2

Palermo
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Drive 31 km, 1 hour 38 min

Norman Palace
Palermo Cathedral
Quattro Canti
Fontana Pretoria
Orto botanico di Palermo
Santuario di Santa Rosalia, Palermo
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You’ll stay in Palermo for 1 night.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Sicily. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Palermo's most popular restaurants, and connect with friendly locals for a true cultural experience.

As the sun sets, rest up and recharge for the next leg of your road trip in Sicily.

Day 3

Palermo
Agrigento
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Drive 162 km, 3 hours 1 min

Museo archeologico regionale Pietro Griffo
Valle dei Templi
Temple of Heracles
Casa Natale di Luigi Pirandello e Tomba
Scala dei Turchi
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On day 3 of your road trip in Sicily, your travel plans include 3 stops at the most scenic, wondrous, and interesting places in the region. Agrigento, Villaseta, and Scavuzzo are on today's agenda. In the evening, you’ll end up in Agrigento, where you will stay for 1 night.

At the end of the day, you will drive to Agrigento, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Agrigento's best restaurants.

Get a good night's sleep and look forward to another great day on the road in Sicily!

Day 4

Agrigento
Ragusa
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Drive 146 km, 3 hours 26 min

Giardino Ibleo
Portale di San Giorgio
Duomo di San Giorgio
Cattedrale di San Giovanni Battista
excape Ragusa - Escape Room
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Experience an unparalleled adventure on day 4 of your road trip in Sicily. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Ragusa. At the end of the day, you will retreat to the hotel of your choice in Ragusa, where will spend 1 night.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Ragusa. Ragusa offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Ragusa. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Relax and look forward to more memorable moments to come!

Day 5

Ragusa
Syracuse
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Drive 98 km, 1 hour 34 min

Neapolis Archaeological Park
Ear of Dionysius
Cathedral of Syracuse
Island of Ortigia
Fountain of Diana
Temple of Apollo
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Your itinerary for day 5 of your road trip in Sicily includes 1 stop and features some of the highlights of Syracuse. At the end of the day, enjoy the comforts of a top-rated hotel in Syracuse, where you'll spend 1 night.

When you’re done exploring for the day, you’ll drive to your hotel in Syracuse. Check in and relax before you head out to tour the city.

Syracuse is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Syracuse.

As the sun sets, rest up and recharge for the next leg of your road trip in Sicily.

Day 6

Syracuse
Catania
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Drive 69 km, 1 hour 30 min

Castello Ursino
Greek - Roman theatre
Villa Bellini/Chiosco Bellini
Piazza Università
Fountain of the Elephant
Basilica Cattedrale di Sant'Agata
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Dive into day 6 of your remarkable road trip in Sicily. Today you'll explore 1 destination, including Catania. At the end of the day, you’ll unwind at one of the finest accommodations in Catania, where you'll spend 1 night.

At the end of the day, you will drive to Catania, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Catania, it's often a good idea to reserve a table in advance.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Sicily.

Day 7

Catania
Taormina
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Drive 56 km, 2 hours 12 min

Isola Bella
Villa Comunale di Taormina
Ancient theatre of Taormina
Chiesa Madonna della Rocca
Porta Catania
Basilica of St. Nicholas of Bari
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On day 7 of your exciting self-drive vacation in Sicily, you’ll soak in the magnificence of 2 destinations, including Mazzarò and Taormina. When you’re not sightseeing, take time to relax at your chosen hotel in Taormina, where you’ll be staying for 1 night.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Taormina. Taormina offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Taormina's most popular restaurants, and connect with friendly locals for a true cultural experience.

Savor another day of unforgettable experiences in Sicily!

Day 8

Taormina
Cefalù
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Drive 212 km, 3 hours 14 min

Rocca di Cefalù
Cathedral of Cefalù
Bastione di Capo Marchiafava
Porta della Pescara (Porta Marina)
Lavatoio Medievale Fiume Cefalino - Cefalù (pa)
Cefalù Beach
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On day 8 of your road trip in Sicily, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Cefalù are on today's agenda. In the evening, you’ll end up in Cefalù, where you will stay for 1 night.

When you’re done exploring for the day, you’ll drive to your hotel in Cefalù. Check in and relax before you head out to tour the town.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Cefalù. Enjoy a relaxing evening as you savor delicious local cuisine.

Raise your glass to another unforgettable day in Sicily!

Day 9

Cefalù
Palermo
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Drive 184 km, 3 hours 53 min

Gole di Tiberio
Parco delle Rimembranze
Parco delle Madonie
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Experience an unparalleled adventure on day 9 of your road trip in Sicily. This exciting part of your journey invites you to discover the renowned landmarks in 3 places, which are San Mauro Castelverde, Castelbuono, and Petralia Sottana. At the end of the day, you will retreat to the hotel of your choice in Palermo, where will spend 1 night.

At the end of the day, you will drive to Palermo, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Palermo's best restaurants.

Head back to your accommodation in Palermo and get some rest to prepare for another magical day of your road trip in Sicily.

Day 10

Palermo - Departure day
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Catacombe dei Cappuccini
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Day 10 of your road trip in Sicily is your departure day. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Sicily!

How it works

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Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.

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Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.

Personalize your itinerary

Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.

Easily make changes

Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.

Enjoy seamless planning

With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.

Explore with confidence

From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

Secure your spot

Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.

Get instant confirmation

Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.

Personalize your itinerary

Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.

Easily make changes

Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.

Enjoy seamless planning

With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.

Explore with confidence

From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

We guarantee

Your trip is protected, personalized, and priced right. No surprises, no stress.

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