Relaxed 10-Day Italy Self-Drive Road Trip With Itinerary from Florence to Rome and Siena

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Aerial view of the Cattedrale di Santa Maria del Fiore in Florence, Italy, overlooking the city
Photo of Florence Aerial View of Ponte Vecchio Bridge during Beautiful Sunny Day, Italy.
Relaxed 10-Day Italy Self-Drive Road Trip With Itinerary from Florence to Rome and Siena
Relaxed 10-Day Italy Self-Drive Road Trip With Itinerary from Florence to Rome and Siena
Relaxed 10-Day Italy Self-Drive Road Trip With Itinerary from Florence to Rome and Siena
Relaxed 10-Day Italy Self-Drive Road Trip With Itinerary from Florence to Rome and Siena
Relaxed 10-Day Italy Self-Drive Road Trip With Itinerary from Florence to Rome and Siena
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Set out on this 10-day relaxed road trip in Italy, where Florence, Orvieto, Rome, Siena, and Pisa offer rich culture, beautiful views, and memorable experiences at every stop!

Travel freely with this relaxed self-drive package in Italy, designed for comfort and exploration. Spend 4 nights in Florence, 4 nights in Rome, and 1 night in Siena, staying at top-rated hotels near the heart of each city. Between drives, indulge in local cuisine, sip refreshing drinks, and enjoy the vibrant atmosphere at popular restaurants and bars along your road trip route in Italy.

Your journey starts in Florence, where your rental car with CDW insurance will be ready for pickup. Choose a vehicle that suits your style, then set off on your 10-day relaxed road trip in Italy to explore its rich culture, fascinating history, and stunning landscapes.

Every stop on this leisurely self-drive holiday comes with handpicked accommodations that make relaxation effortless. Choose from elegant 5-star hotels with breathtaking views or comfortable 3-star stays that offer excellent value, all providing a welcoming retreat after a day on the road.

With your self-drive itinerary in Italy already planned, you’ll enjoy the country’s most celebrated sights without the rush. Marvel at the stunning Trevi Fountain and soak in the atmosphere of the magnificent Colosseum.

Enjoy each stop as you explore the history, architecture, and character of each destination on this Italy road trip itinerary for 10 days.

As you travel between destinations, you’ll have plenty of time to explore local markets and boutique shops. These stops give you the chance to find unique souvenirs, taste regional specialties, and experience everyday life in Italy.

If you want to make your 10-day relaxed self-drive tour in Italy even more memorable, add optional tours or activities. Join a guided excursion, discover hidden neighborhoods, or spend an afternoon in your favorite market. Each choice deepens your connection to the places you visit.

Alongside these experiences, your laid-back self-drive package in Italy includes 9 nights in comfortable hotels, a rental car for 10 days, and convenient access to nearby dining options. You can also add flights and entry tickets to shape the trip exactly how you want it. With 24/7 travel support and a mobile app keeping your itinerary and documents organized, you can enjoy a relaxed drive and savor every mile of the road ahead.

Turn your travel plans into reality. Book your 10-day relaxed self-drive road trip in Italy today and enjoy a journey filled with discovery, freedom, and unforgettable moments!

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Driver’s age is 30 - 65
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Day1

Day 1

  • Florence - Arrival day
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  • Central Market
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Your relaxed road trip through Italy starts when you reach the incredible city of Florence, where you'll stay for 3 nights. You'll pick up your rental car in Florence and begin your adventure in Italy.

Florence is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Central Market. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Florence. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Ristorante Oliviero 1962, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Di Poneta Novoli is another top choice with a popular menu. You could also check for a table at Caffe San Firenze. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Florence tonight.

As the day is coming to an end, retreat to your hotel for some rest, or head out to a bar to celebrate your time in Florence. The bars in Florence make the perfect setting for a laid-back drink and chilled hangout with your travel companions.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Manifattura stands out as an excellent choice for a post-dinner cocktail. Alternatively, Se·sto On Arno Rooftop Bar offers an ideal atmosphere to enjoy the pleasures of the night. Il Vinile is also a great option that provides a perfect setting for a relaxing evening.

Raise a toast as you look back on the highlights of today’s relaxed road trip in Italy. Enjoy your first taste of Florence as you soak in the city’s unique vibe.

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Day2

Day 2

  • Florence
  • More

Drive 6 km, 45 min

  • piazza della Signoria
  • Palazzo Vecchio
  • Uffizi Gallery
  • Ponte Vecchio
  • piazzale Michelangelo
  • More

Day 2 of your relaxed road trip through Italy means 24 hours of making the best memories in Florence. You’ll go sightseeing at famous attractions in Florence. In the evening, you will experience one of the most popular dining spots in the city. So buckle up and prepare to be blown away by Florence!

Let Piazza Della Signoria set the tone for the day. Spend some time admiring this remarkable public square before continuing your journey. Palazzo Vecchio is your next stop. This locally renowned palace is one of the best-rated sights in Florence.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Uffizi Gallery. This picture-perfect art gallery is a sight to behold. To round off your sightseeing experience, visit Ponte Vecchio and Piazzale Michelangelo.

Another way to make your easygoing and relaxed road trip in Italy more special is by joining unique tours and activities. Florence offers a wide selection of experiences for every traveler.

Exploring the food culture in Florence offers you an exciting chance to connect with locals and experience diversity along your relaxed road trip. When you’re ready to eat, we recommend you visit one of the best dining spots in the city.

Treat yourself to an extraordinary dining experience at Enoteca Pinchiorri, a 3-star Michelin restaurant offering an incredible italian contemporary menu. Alternatively, if your taste buds call for something different, Santa Elisabetta is one of the best restaurants for creative and mediterranean cuisine in Florence. This 2-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Gucci Osteria da Massimo Bottura. As a top-rated establishment with 1 Michelin star, it is an ideal choice for italian contemporary and international cuisine in the city.

A visit to a top-rated local bar is one of the most refreshing ways to cap off a beautiful night in Florence.

Keep the evening going at Bar 50 Rosso, a great choice for enjoying the after-dinner hours with a drink. You could also go to Bitter Bar, which offers a similarly pleasant setting and great drinks. Another option is Archea Brewery, which provides an inviting environment for unwinding after a busy day out.

Raise your glass and toast to another unforgettable, laid-back road trip adventure in Italy!

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Day3

Day 3

  • Florence
  • More

Drive 4 km, 56 min

  • Basilica of Santa Croce in Florence
  • Galleria dell'Accademia
  • Cathedral of Santa Maria del Fiore
  • Basilica of Santa Maria Novella
  • More

On day 3 of your leisurely self-drive tour across Italy, you’ll go deep into Florence, where you'll stay for 1 night, and see some of the city’s unforgettable attractions. To learn more of the city's culture, you'll also dine at the most popular restaurants in Florence, and meet locals along the way!

Experience Basilica Of Santa Croce In Florence, a locally renowned church in the city. Then, head to Galleria Dell'accademia and soak in the ambiance of this respected art gallery.

There are many interesting places to see in Florence, and when you are ready for more, go to Cathedral Of Santa Maria Del Fiore. This is one of the city’s most top-rated UNESCO world heritage-listed spots of interest. After exploring the church, visit the notable Basilica Di Santa Maria Novella, Firenze (fi).

Italy makes the perfect setting for a calming but fun road trip experience. Aside from amazing sights, Italy also offers plenty of tours to enhance your relaxed road trip experience.

When it’s time to eat, the city has a variety of restaurants and cuisines to suit your palate and complement your relaxed road trip experience. Take a leisurely walk around Florence, while looking for a place to eat. Or, check out our top recommendations and treat yourself to a nice meal.

Make sure to reserve a table at Ristorante Buca Mario, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Agricola Toscana, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Eataly Firenze, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

As the day is coming to an end, retreat to your hotel for some rest, or head out to a bar to celebrate your time in Florence. The bars in Florence make the perfect setting for a laid-back drink and chilled hangout with your travel companions.

Unwind after your meal by stepping into Gosh*. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Antico Caffè Del Moro - Art Bar Firenze offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Quelo Bar, another top-rated bar in the area.

Soak in the unique atmosphere of Florence as you commemorate this day of your relaxed road trip with a toast. Cheers to a memorable, leisurely self-drive holiday in Italy!

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Day4

Day 4

  • Florence
  • Orvieto
  • Rome
  • More

Drive 289 km, 3 hours 59 min

  • Well of St Patrick
  • Orvieto Cathedral
  • Orvieto subterranea
  • Torre del Moro Orvieto
  • More

On day 4 of your laid-back road trip adventure in Italy, you can visit several remarkable places. With the freedom and flexibility of a self-drive tour, you decide how much time to spend in each, making the most of these memorable destinations.

Fasten your seatbelt and make your way to your next stop — Orvieto, home to many well-known sights in the region. Keep in mind that your travel time from Florence to Orvieto may take around 1 hour 54 min without traffic disruptions. Upon arrival in Orvieto, we highly recommend checking out some of the top attractions.

One of our top recommendations for your sightseeing is Well Of St. Patrick. Spend some time admiring the respected features of the monument before you continue to your next stop.

Fasten your seatbelt and make your way to your next stop — Orvieto, home to many well-known sights in the region. Keep in mind that your travel time from Florence to Orvieto may take around 1 hour 54 min without traffic disruptions. Upon arrival in Orvieto, we highly recommend checking out some of the top attractions.

Orvieto Cathedral is a notable church we recommend visiting today. Discover its history-steeped features before continuing your self-guided tour to Orvieto Underground, a visually striking cave system that’s well-regarded in the area.

Next, stop by Torre Del Moro Orvieto, a picture-perfect monument.

In Rome, you’ll find plenty of places to unwind after a day on the road. Our top recommendations go perfectly with your laid-back road trip in Italy.

When you’re not driving and exploring some of the best places in Italy, it’s time to make your relaxed road trip even more comforting. Sit down for a lovely meal at one of the best restaurants in Rome.

Treat yourself to an extraordinary dining experience at La Pergola, a 3-star Michelin restaurant offering an incredible mediterranean and contemporary menu. Alternatively, if your taste buds call for something different, Il Pagliaccio is one of the best restaurants for creative and innovative cuisine in Rome. This 2-star Michelin-awardee earns consistently high praises from guests. We also recommend checking out the menu at Enoteca La Torre. As a top-rated establishment with 2 Michelin star, it is an ideal choice for mediterranean and creative cuisine in the city.

Before calling it a day, visit one of the best bars in Rome. There, you can look back on the highlights of today’s pleasant and invigorating travel experiences, have friendly conversations with locals, and unwind.

After enjoying a fulfilling meal, continue your evening at La Botticella Of Poggi Giovanni, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Almalu Trastevere offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Viminale Di Pepi Maurilio provides an excellent environment for a relaxed and enjoyable evening.

Raise your glass in celebration of your freedom and relaxed road trip adventure in Italy!

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Day5

Day 5

  • Rome
  • More

Drive 8 km, 1 hour 2 min

  • Trevi Fountain
  • Piazza di Spagna
  • Spanish Steps
  • piazza del Popolo
  • Villa Borghese
  • More

Day 5 introduces you to many popular attractions and activities in Rome, further proving that leisurely self-drive tours in Italy are extraordinary.

Start your day at Trevi Fountain. This symbolic monument is an iconic place to see in Rome. Then, wander over to Piazza Di Spagna. If romantic sites excite you, this public square will be right up your alley. Nearby, you’ll also find Spanish Steps. This symbolic public square is a favorite among visitors.

Rome offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Piazza Del Popolo is a famous spot in the city that will captivate you with its unique charm. When you’re done at the public square, don’t forget to check out the mesmerizing Villa Borghese. Take a moment to appreciate the fascinating details of this extraordinary park.

Gain a one-of-a-kind experience on your unhurried and relaxed road trip across Italy by joining a traveler-approved tour in Florence. There are so many fun and eye-opening activities to try out in Florence that will make your slow-paced self-drive tour in Italy more memorable. Check out all the most recommended and top-rated tour options in the city of Rome to find the best options for you!

When you’re not driving and exploring some of the best places in Italy, it’s time to make your relaxed road trip even more comforting. Sit down for a lovely meal at one of the best restaurants in Rome.

Enjoy a lovely dining experience at RomAntica, a popular restaurant in Rome. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Rome at Coso Ristorante, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated DEROMA - Farine Romane. It’s yet another ideal choice to enhance your time in Rome tonight.

As the day is coming to an end, stop at some of Rome’s best bars to celebrate this day of your slow-paced adventure in Italy.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Sant' Eustachio Caffè, known for its inviting atmosphere. Yellowsquare Rome is another great option if you’re looking for a place to get the night started. Similarly, Caffè Portofino provides a great setting to enjoy the night away.

A leisurely self-drive holiday in Rome can’t get any better than this! Toast to another amazing day in Italy!

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Day6

Day 6

  • Rome
  • More

Drive 17 km, 1 hour 28 min

  • Foro Italico
  • Altare della Patria
  • Roman Forum
  • Colosseum
  • Circus Maximus
  • More

Day 6 of your relaxed road trip through Italy means 24 hours of making the best memories in Rome. You’ll go sightseeing at famous attractions in Rome. In the evening, you will experience one of the most popular dining spots in the city. So buckle up and prepare to be blown away by Rome!

Your adventure in Rome is only getting started when you visit Foro Italico, a well-known local hot spot. Another notable attraction to explore is Altare Della Patria. This well-known monument is known for its photogenic appeal.

After soaking in the highlights of these sights, take some time to wander Rome's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Roman Forum. This picture-perfect archeological site offers a fascinating experience that many visitors find memorable. Colosseum is also worth visiting, along with Circus Maximus. These standout landmarks offer unique experiences that add to the day’s enjoyment.

Make the most of your time in the country by joining activities that let you discover more about Italy. Check out all of the tours you can join this day of your leisurely self-drive holiday in Italy and ensure the experience of a lifetime.

After a laid-back day of exploring top attractions in the area, it’s an excellent idea to sit down for a lovely and peaceful dinner. We’ve collected the most recommended restaurants in the city for you, so you can check out the menus and make your reservation in advance.

Treat yourself to a delightful dinner at Hotel de Russie, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try La Taverna Italiana? It's another excellent option with a diverse menu. Consider reserving a table at The Parrot Bar as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.

If you feel like it, head out to a bar to celebrate another fantastic day in Rome and take the pulse of the city’s nightlife. Enjoy the night without rushing to fully appreciate it.

Keep the excitement of the evening going by visiting a bar or two. The Apartment Bar Roma is an excellent place to start. You could also check out Hotel Hassler Roma, offering a different kind of charm.

Cherish every minute of your relaxed road trip vacation across Italy.

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Day7

Day 7

  • Rome
  • More

Drive 6 km, 57 min

  • Castel Sant'Angelo
  • Piazza Navona
  • Pantheon
  • largo di Torre Argentina
  • Campo de' Fiori
  • More

On day 7 of your leisurely self-drive tour across Italy, you’ll go deep into Rome, where you'll stay for 1 night, and see some of the city’s unforgettable attractions. To learn more of the city's culture, you'll also dine at the most popular restaurants in Rome, and meet locals along the way!

Enjoy all that Castel Sant'angelo has to offer. This is an extraordinary castle you should not miss. Another must-see is Piazza Navona, an iconic public square in Rome.

When you’re ready for the next sight, head to Pantheon. From there, take a leisurely stroll to Largo Di Torre Argentina, another of the city’s locally renowned attractions. We recommend continuing your self-guided tour at Campo De' Fiori, a romantic place of interest in the city.

Another way to make your easygoing and relaxed road trip in Italy more special is by joining unique tours and activities. Rome offers a wide selection of experiences for every traveler.

Exploring new places makes you hungry. Luckily, Rome has multiple restaurants that offer fantastic dining experiences to continue your laid-back and stress-free discovery of the city.

Savor the flavors at Sofitel Roma Villa Borghese, a top pick for dinner tonight. Alternatively, Centro beckons with its unique menu offerings. Also, consider Ristorante Tema. With its consistent customer satisfaction, it’s an excellent option for dining in Rome tonight.

Before calling it a day, visit one of the best bars in Rome. There, you can look back on the highlights of today’s pleasant and invigorating travel experiences, have friendly conversations with locals, and unwind.

Grab yourself a drink and savor every moment of your relaxed road trip experience in Italy!

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Day8

Day 8

  • Rome
  • Vatican City
  • Siena
  • More

Drive 242 km, 2 hours 57 min

  • St Peter's Basilica
  • More

Day 8 of your leisurely self-drive tour in Italy offers another chance for an in-depth travel experience. You’ll stay in Siena for 1 night.

Continue your road trip and head to your next destination, Vatican City, Vatican City. This car ride takes around 9 min.

St. Peter's Basilica is an iconic major basilica we recommend visiting today.

Continue your laid-back road trip in Italy as you make your way to Siena. Here, you’ll find top hotels and accommodations in the city, perfect for relaxing and recharging.

Mealtimes are the perfect opportunities to immerse yourself in the local culture of Italy. When you're not appreciating the best places to visit in Siena, explore the city like a local by trying out the best restaurants in the area.

Make sure to reserve a table at Enoteca I Terzi, an iconic dining spot in Siena. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante Tar-Tufo, a popular restaurant in Siena. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Antica Trattoria Papei, a hidden gem nestled in Siena. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

As the day is coming to an end, retreat to your hotel for some rest, or head out to a bar to celebrate your time in Siena. The bars in Siena make the perfect setting for a laid-back drink and chilled hangout with your travel companions.

Let the evening flow smoothly from dinner to drinks at Meet Life Cafè, a top-rated bar in the area. For other recommendations, Maudit Pub provides a perfect setting for rounding out your night with style and great drinks. Likewise, Bar Impero Siena offers a memorable night with diverse drink options and excellent service.

A leisurely self-drive holiday in Vatican City can’t get any better than this! Toast to another amazing day in Italy!

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Day9

Day 9

  • Siena
  • Pisa
  • Florence
  • More

Drive 216 km, 3 hours 30 min

  • piazza del Campo
  • Siena Cathedral
  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Campo santo
  • More

Day 9 of your relaxed road trip in Italy will take you on a self-paced journey to more than one incredible place in one day. See some of the best attractions in Italy, taste the most delectable foods and exquisite drinks, and make incredible memories as you go!

Visiting Piazza Del Campo is always a good idea. This extraordinary public square is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the history-steeped wonders of Siena Cathedral, a must-see church in the city.

Set your GPS to Pisa and hit the road. Expect a journey of approximately 1 hour 50 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Pisa beckons with new experiences!

One of our top recommendations for your sightseeing is Leaning Tower Of Pisa. Spend some time admiring the breathtaking features of the monument before you continue to your next stop. Then, head to Piazza Del Duomo, Pisa. This timeless public square is a traveler-favorite in the city.

If you're keen to see more, continue to Campo Santo. Feed your curiosity by learning something new about the cemetery.

You'll be staying in Florence on this laid-back road trip through Italy. You'll stay here for 1 night.

After a laid-back day of exploring top attractions in the area, it’s an excellent idea to sit down for a lovely and peaceful dinner. We’ve collected the most recommended restaurants in the city for you, so you can check out the menus and make your reservation in advance.

Enjoy a delicious meal at Tijuana, a highly-rated dining destination in Florence. If you're eager to try something different, consider Djària - American Bar, another top spot with a tantalizing menu. You might also want to secure a reservation at The Florence Irish Pub. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Florence this evening.

After dinner, it’s time to fall in love with the amazing nightlife in Florence and unwind at some of the best bars in the city.

Grab a drink and enjoy every passing minute of this night of your relaxed road trip experience in Italy!

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Day10

Day 10

  • Florence - Departure day
  • More
  • Oltrarno
  • More

Day 10 of your relaxed road trip in Italy is your departure day. If you’re flying home, return your rental car with time to spare. For a stress-free farewell, book a later flight and enjoy a final, relaxed day in Florence.

Make the most of your final day in Italy by visiting Florence’s iconic markets and shopping establishments in the buzzing San Lorenzo Market. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation.

At the top of the list of places to visit today is Oltrarno, a neighborhood that captures the true essence of Florence. Take your time to uncover its best sides and enjoy its proximity to many of the area’s best attractions.

Over a good meal, take a moment to unwind and reflect on the past 10 days of your relaxed road trip. Savor one last traditional dish in Florence, or keep it light with a quick bite before you go.

Have a fantastic dining experience at Ristorante Buca Niccolini, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Essenziale offers an enticing alternative with its varied menu.

Give yourself enough time to wave goodbye to Florence and begin your journey home. The unforgettable experiences you’ve collected along your 10-day relaxed road trip in Italy is a story you will tell for the rest of your life.

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Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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