10-Day Italy Self-Drive Road Trip With Itinerary from Genoa to La Spezia, Florence, San Gimignano, and Rome

Day 2 of your road trip will take you to the best attractions Genoa has to offer. Cherish the 1 night you have left in the city and use the provided itinerary to discover what to see in Genoa.

Make time for Lighthouse Of Genoa, an up-and-coming lighthouse that is worthwhile a visit in the city. Nearby, you’ll find Galata Museo Del Mare (complex), enchanting visitors with its heritage-rich appeal. Continue your exploration at Via Garibaldi. This street is one of the city’s most intriguing spots.

Enjoy the freedom of exploring Genoa at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Palazzo Podestà. After exploring the palace, head to the spectacular Aquarium Of Genoa. Lastly, wrap up today’s self-guided sightseeing tour with a visit to Porto Antico, a place of instagrammable interest in Genoa.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Genoa. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delicious dinner at Zeffirino, an excellent option for tonight's dining. Looking for something different? Trattoria Vegia Zena offers a tantalizing alternative with its diverse menu. And don’t miss Trattoria delle Grazie. Known for great service, it’s a fantastic choice for tonight in Genoa.

Raise your glass and celebrate another amazing day of your road trip in Italy!

Your itinerary for day 3 of your road trip in Italy includes 3 stops and features some of the highlights of Corniglia, Manarola, and Riomaggiore. At the end of the day, enjoy the comforts of a top-rated hotel in La Spezia, where you'll spend 1 night.

As you explore Corniglia’s charming streets, take in the lively atmosphere and get to know the character of the village.

Continue your road trip and head to your next destination, Corniglia. This car ride takes around 1 hour 44 min.

Cinque Terre National Park is a locally renowned national park we recommend visiting today. Discover its mesmerizing features before continuing your self-guided tour.

It’s time to gear up for the next part of your road trip adventure. Under favorable conditions, your drive to Manarola may take around 15 min. Upon your arrival in Manarola, you’ll be greeted with the opportunity to do some sightseeing and exploring.

Manarola Overlook Viewpoint is an underrated observation deck we recommend visiting today. Discover its awe-inspiring features before continuing your self-guided tour.

Embrace the thrill of the open road as you wave goodbye to Riomaggiore and set your GPS to La Spezia. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 26 min. Upon reaching La Spezia, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Savor the day by heading to Riomaggiore, an increasingly popular sightseeing destination that draws visitors from near and far. When you're done, continue to Castle Of Riomaggiore, where you can soak in the standout surroundings.

At the end of the day, you will drive to La Spezia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in La Spezia, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at The Colombaio Park, a top-rated dining destination in La Spezia.

Celebrate another amazing day of your road trip adventure in Italy!

On day 4 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Pisa are on today's agenda. In the evening, you’ll end up in Florence, where you will stay for 2 nights.

When you’re ready to jump back into the car and say goodbye to La Spezia, you’ll hit the road in the direction of Pisa. This drive usually takes around 1 hour 8 min.

Set out on a self-guided sightseeing tour at Leaning Tower Of Pisa and explore the noteworthy features. Next, make your way to Angelo Caduto, another highlight in Pisa. When you’re done exploring the point of interest, continue to Pisa Cathedral, a historic church.

Nearby, you will also find Piazza Del Duomo, Pisa. This wondrous public square is a top place to see in the area. Lastly, head to Campo Santo, a detailed cemetery that is perfect for some final exploring in the city.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a delicious dinner at Ristorante Oliviero 1962, an excellent option for tonight's dining. Looking for something different? Di Poneta Novoli offers a tantalizing alternative with its diverse menu. And don’t miss Caffe San Firenze. Known for great service, it’s a fantastic choice for tonight in Florence.

Unwind after your meal by stepping into Manifattura. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Se·sto On Arno Rooftop Bar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Il Vinile, another top-rated bar in the area.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

Day 5 offers an itinerary packed with the best things to see in Genoa. You’ll stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.

Florence is brimming with adventures.

Visiting Basilica Of Santa Croce In Florence is always a good idea. This captivating church is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the picture-perfect wonders of Uffizi Gallery, a must-see art gallery in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Ponte Vecchio. This timeless historical landmark offers an enriching experience. For a change of pace, head to Palazzo Vecchio, where you can take in romantic features. Conclude your self-guided sightseeing tour with a visit to Piazza Della Signoria and Cathedral Of Santa Maria Del Fiore These sights offer a fulfilling end to a perfect day.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Enjoy a lovely dining experience at Ditta Artigianale, a popular restaurant in Florence. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Florence at Trattoria Da Burde, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Casa Toscana. It’s yet another ideal choice to enhance your time in Florence tonight.

Unwind after your meal by stepping into Bar 50 Rosso. This venue is celebrated for its extensive drink selections and cozy vibes. Alternatively, Bitter Bar offers a dynamic and energetic atmosphere for a glass or two. Don’t overlook Archea Brewery, another top-rated bar in the area.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

Experience an unparalleled adventure on day 6 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 places, which are Siena and San Gimignano. At the end of the day, you will retreat to the hotel of your choice in San Gimignano, where will spend 1 night.

When you’ve had your share of Florence, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Siena. Your travel time is around 1 hour 12 min.

Savor the day by heading to Siena Cathedral, an interesting church that draws visitors from near and far. When you're done, continue to Piazza Del Campo, where you can soak in the enchanting surroundings.

Next, explore Tower Of Mangia, yet another curiosity-inducing place to see in the area.

After soaking in Siena’s unique atmosphere, jump into the car with a full heart and drive in the direction of your next destination: San Gimignano. Expect your car journey to take a minimum of 52 min. When you arrive in San Gimignano, it's time to take a break from the road.

Spend your afternoon discovering Chiesa Di Sant'agostino, a curiosity-inducing church known for its culturally significant features. Next, continue your sightseeing at Palazzo Comunale, Pinacoteca, Torre Grossa, an underrated museum.

If you're starting to feel hungry, this is a great time for a break at a nearby restaurant or cafe. When you're ready for more, stop by Piazza Del Duomo and uncover the details of this UNESCO world heritage-listed public square.

When you’re done exploring for the day, you’ll drive to your hotel in San Gimignano. Check in and relax before you head out to tour the village.

After a day of adventure, treat yourself to an exquisite dinner at one of San Gimignano's best restaurants.

Head back to your accommodation in San Gimignano and get some rest to prepare for another magical day of your road trip in Italy.

Dive into day 7 of your remarkable road trip in Italy. Today you'll explore 1 destination, including Rome. At the end of the day, you’ll unwind at one of the finest accommodations in Rome, where you'll spend 2 nights.

Embrace the thrill of the open road as you wave goodbye to San Gimignano and set your GPS to Rome. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 3 hours 8 min. Upon reaching Rome, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

For a more meaningful self-guided tour of the city's best attractions, visit Castel Sant'angelo, an impressive castle that is sure to impress. Take in the surroundings and enjoy the freedom of exploring at your own pace before you continue your journey. Next, head to Spanish Steps and admire its romantic features.

When you’re ready, continue to Piazza Di Spagna, a timeless public square beloved by locals and tourists alike. Don't miss out on Trevi Fountain, another highlight of the area that promises a memorable visit. Not far away, you’ll also find Altare Della Patria, a culturally significant place to see that you won’t regret spending some extra time discovering.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Rome. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Make sure to reserve a table at La Bottega Roma, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Pasta In Corso, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Trattoria Vecchia Roma, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, La Botticella Of Poggi Giovanni stands out as an excellent choice for a post-dinner cocktail. Alternatively, Almalu Trastevere offers an ideal atmosphere to enjoy the pleasures of the night. Bar Viminale Di Pepi Maurilio is also a great option that provides a perfect setting for a relaxing evening.

Savor another day of unforgettable experiences in Italy!

Greet day 8 of your road trip in Italy with a smile and start your day with a hearty breakfast. You have 1 night to stay in Rome, so get ready to make the most of your time in the region. On the agenda for this day, you’ll find only the best things to see and do in Vatican City and Rome.

Vatican City is brimming with adventures. Trastevere is a neighborhood that stands out as one of the must-see places in Vatican City. Take a moment to explore its distinct atmosphere, and don’t miss the popular sightseeing spots just a short walk away.

Make time for Roman Forum, an iconic archeological site that is worthwhile a visit in the city. Nearby, you’ll find Colosseum, enchanting visitors with its picture-perfect appeal. Continue your exploration at Pantheon. This monument is one of the city’s most wondrous spots.

Enjoy the freedom of exploring Rome at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Piazza Navona.

Continue your road trip and head to your next destination, Vatican City.

Savor the day by heading to St. Peter's Basilica, a timeless major basilica that draws visitors from near and far.

When you’re done exploring for the day, you’ll return to Rome and your accommodation.

Rome is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Rome.

Enjoy a delicious meal at RomAntica, a top-rated dining destination in Rome. If you're in the mood to try something new, consider Coso Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at DEROMA - Farine Romane. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Rome this evening.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Sant' Eustachio Caffè, a well-loved spot among locals and tourists. Or, head to Yellowsquare Rome. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Caffè Portofino, another top-rated place in the area.

Savor another day of unforgettable experiences in Italy!

On day 9 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Orvieto. When you’re not sightseeing, take time to relax at your chosen hotel in Genoa, where you’ll be staying for 1 night.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Orvieto. This drive usually takes around 1 hour 35 min, without any stops or traffic disruptions.

When you're ready for some sights, head to Well Of St. Patrick, a well-known monument in Orvieto. Explore its breathtaking features at your own pace before you continue your journey.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Orvieto. This drive usually takes around 1 hour 35 min, without any stops or traffic disruptions.

One of our top recommendations for your sightseeing is Orvieto Cathedral. Spend some time admiring the inviting features of the church before you continue to your next stop. Then, head to Orvieto Underground. This frequently visited cave system is a traveler-favorite in the village.

If you're keen to see more, continue to Torre Del Moro Orvieto. Feed your curiosity by learning something new about the monument. Next, take your journey to Pozzo Della Cava, an underrated cave.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Genoa. Genoa offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Genoa is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Genoa.

Treat yourself to a delightful dinner at Osteria Sant'Ilario, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try La Cialtroneria? It's another excellent option with a diverse menu. Consider reserving a table at Manhattan Bar as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Genoa.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.