10-Day Italy road trip from Genoa to Florence, Rome, and Siena

Your road trip adventure in Italy begins as soon as you reach the incredible city of Genoa. You’ll stay in Genoa for 2 nights, experiencing all the best things to do and see in the city.

Genoa has many popular destinations you can explore. You could visit attractions like the incredible porto antico. This attraction is a port and has an average rating of 4.5 out of 5 stars by 12,414 visitors.

When you're done sightseeing for the day, you'll check in at one of the best hotels or places to stay in the city. Your stay promises to be a delightful continuation of your exploration, providing comfort and tranquility to recharge for the adventures that lie ahead.

When you’re ready for dinner, we recommend you try one of the best restaurants in the city of Genoa, Osteria di Vico Palla. The restaurant is rated an average of 4.4 out of 5 stars by 3,057 customers.

Another of the best restaurants in the city of Genoa is Trattoria Ugo. This restaurant is rated an average of 4.4 out of 5 stars by 1,814 customers.

Locals recommend Trattoria dell'Acciughetta as one of the best restaurants in the city of Genoa. This restaurant has an average rating of 4.4 out of 5 stars by 1,398 customers.

Genoa also has several great bars that will fit all travel budgets. One of the best bars in the city of Genoa is Scurreria Beer & Bagel. This bar has an average rating of 4.5 out of 5 stars by 1,480 customers.

Another of the best bars in the city of Genoa is Soho. This bar is rated an average of 4.4 out of 5 stars by 1,307 customers.

Locals also enjoy Rustichello Restaurant. This bar has an average rating of 4.5 out of 5 stars by 861 customers.

Enjoy toasting the start of your 10-day vacation in Italy!

As you rise to greet the dawn on day 2 of your epic road trip in Italy, you'll awaken to the bustling city of Genoa. Today, you'll hit the road once again, setting off on a journey towards the stunning city of Florence. You’ll stay in Florence for 3 nights. But before you begin your drive, we recommend taking the time to explore some of Genoa’s must-see attractions and local hotspots.

If you’re curious to see more of Genoa, start your day with a visit to the amazing piazza De Ferrari. This much-appreciated square and attraction is rated 4.6 out of 5 stars by 34,312 visitors.

You could also stop at another of the best local travel destinations in the area, the fascinating Genoa Cathedral. This cathedral and spectacular attraction has an average rating of 4.6 out of 5 stars from 8,971 visitors.

We also recommend you spend some time at the popular Forte Sperone to make the most of your road trip across Italy. The spectacular Forte Sperone is a top-tier point of interest that has been rated an average of 4.2 out of 5 stars by 537 visitors.

After soaking up all the sights and sounds that Genoa has to offer, you'll be ready to hit the open road and continue your unforgettable road trip towards the city of Florence. Florence offers plenty of options for top-rated hotels and other places to stay that fit all travel budgets.

After you’ve settled into your accommodation, we recommend a dinner at the popular Ristorante Paoli. This popular restaurant is one of the locals’ most recommended restaurants in the city, with ratings of 4.9 out of 5 stars in 6,031 reviews.

The remarkable Ristorante Oliviero 1962 is another top restaurant in Florence we recommend. This restaurant offers an unforgettable dining experience and is rated an average of 4.7 out of 5 stars by 1,046 customers.

If you would rather go somewhere else, the famous Il Vezzo is also an excellent choice. This well-loved restaurant is rated an average of 4.8 out of 5 stars by 862 customers.

After your meal, we recommend you drink at one of the best bars in Florence, the fantastic Manifattura. This bar has an average rating of 4.7 out of 5 stars by 509 customers.

To end your night the best way possible, we recommend going to the wonderful Ditta Artigianale. This bar offers a great variety of drinks and has been rated an average of 4.3 out of 5 stars by 1,877 customers.

Another bar with a great atmosphere is Archea Brewery. This bar is rated an average of 4.7 out of 5 stars by 723 customers, so don’t forget to check this one out as well!

Celebrate another amazing vacation day filled with adventure in Italy!

On day 3 of your road trip across Italy, you’ll have the perfect day exploring the wonderful city of Florence. You’ll stay in Florence for 2 nights, meaning you have plenty of time to discover the best things to see and do in the area.

We recommend you stay at the Nil Hotel, one of the best 4-star hotels in the city of Florence. This hotel has an average rating of 4.1 out of 5 stars by 3,288 guests.

The best luxury hotel option in the city of Florence is the 5-star Ville sull'Arno. The hotel is rated an average of 4.5 out of 5 stars by 1,297 guests.

One of the best hotels we recommend in the city of Florence is the 3-star Argentina. This 3-star hotel has an average rating of 4.1 out of 5 stars by 2,994 guests.

Our flexible booking system will automatically provide you with the best alternatives if these hotels are not available.

You'll have easy access to popular travel destinations in the city of Florence, like the outstanding piazzale Michelangelo. This attraction has an average rating of 4.8 out of 5 stars by 77,744 visitors.

Basilica of Santa Croce in Florence is another popular attraction you could visit in the city of Florence. This incredible attraction is a church and has been rated an average of 4.7 out of 5 stars by 28,544 visitors.

One of the best attractions you could visit in the city of Florence is the extraordinary piazza della Signoria. This square is rated an average of 4.8 out of 5 stars in 66,956 reviews.

As the day moves along, one attraction you’ll probably want to visit is the incredible Uffizi Gallery. Up to 2,011,219 people visit this attraction every year. Around 61,794 visitors have given this national museum an average rating of 4.7 out of 5 stars.

Today you'll also have the opportunity to spend some time at the fantastic Ponte Vecchio. Ponte Vecchio is a popular deck arch bridge, rated an average of 4.7 out of 5 stars by 118,099 travelers.

Come to Florence prepared by adding some tours and tickets to your vacation package. Book a popular and budget-friendly activity you can do on this day in Florence.

After a day of exploring, try one of the best restaurants in the city of Florence.

We recommend you eat at a delicious restaurant that locals enjoy, like Ristorante Le Volte Firenze, after your day of exploring the city of Florence. This excellent restaurant has an average rating of 4.7 out of 5 stars by 536 customers.

Le Cappelle Medicee is another of the best restaurants in the city of Florence. This restaurant is rated an average of 4.6 out of 5 stars by 1,574 customers.

Another of the best restaurants in the city of Florence is La Giostra. The restaurant has an average rating of 4.4 out of 5 stars by 1,432 customers.

Locals recommend Locale Firenze, one of the best bars in the city of Florence, for a refreshing evening drink to finish your day. This bar is rated an average of 4.6 out of 5 stars by 771 customers.

Alternatively, you could choose another of the most popular bars in the city of Florence, Djària - American Bar. This bar has an average rating of 4.8 out of 5 stars by 182 customers.

Caffe San Firenze is also one of the best bars in the city of Florence. This bar is rated an average of 4.3 out of 5 stars by 1,268 customers.

It's a perfect place to relax and enjoy another amazing evening in Italy.

Day 4 of your road trip will take you to the best attractions Florence has to offer. Cherish the 1 night you have left in Florence by discovering the best things there are to see and do in the city.

There are plenty of attractions, markets, and restaurants for you to experience today in the city of Florence. Your accommodation will be conveniently located close to several of the best attractions you won't want to miss.

You'll be able to visit more of the best travel destinations in the city of Florence, like the extraordinary Basilica di Santa Maria Novella, Firenze (FI). This attraction is an archive and has an average rating of 4.7 out of 5 stars by 23,075 visitors.

Another of the best travel destinations in Florence is the spectacular Central Market. This attraction is a top-tier point of interest and is rated an average of 4.4 out of 5 stars by 43,100 visitors.

You could then travel to the amazing Cathedral of Santa Maria del Fiore. This church has an average rating of 4.8 out of 5 stars by 76,359 visitors.

Galleria dell'Accademia is another stop you might want to add to your itinerary. This national museum is a popular destination among visitors in Florence. Rated at an average of 4.6 out of 5 stars by 34,429 visitors, it’s one many travelers find worthy a visit. In one single year, this attraction usually gets more than 1,719,645 visitors.

Your discovery of Florence does not have to stop there. Check out the fantastic selection of tours and tickets offered in Florence on this day of your trip.

After a long day of exploring some of the most popular attractions in Italy, be sure to eat at Ristorante La Grotta Toscana, which is considered one of the best restaurants in the city of Florence. This restaurant is a local favorite and has an average rating of 4.4 out of 5 stars by 1,038 customers.

Alternatively, another of the top restaurants in the city of Florence is the popular Il Granaio Ristorante. This restaurant is rated an average of 4.6 out of 5 stars by 667 customers.

When you’ve finished your meal, SE·STO on Arno Rooftop Bar is one of the best bars in the city of Florence for an after-dinner drink. This bar has an average rating of 4.5 out of 5 stars by 1,020 customers.

The Florence Irish Pub is another of the most popular bars in the city of Florence. This bar is rated an average of 4.6 out of 5 stars by 426 customers.

Alternatively, a great bar that locals enjoy in the city of Florence is Il Vinile. Il Vinile has an average rating of 4.7 out of 5 stars by 376 customers.

Stopping at one of these popular bars is the perfect way to celebrate another incredible day in the magical city of Florence!

You’ll stay in Rome for 3 nights.

One of the best places to explore in the city of Tivoli today is Villa d'Este. This excellent attraction is a giardino all'italiana that has been rated an average of 4.7 out of 5 stars by 25,000 visitors. Each year, Villa d'Este attracts over 139,855 local and international travelers.

We also recommend you visit the amazing Fontana dell'Ovato (o di Tivoli), an outstanding best-rated sightseeing destination, in the city of Tivoli. Around 176 travelers rated this attraction with 4.8 out of 5 stars.

To experience the local culture, see more of Italy, and meet new people at the same time, we highly recommend you go on a tour. You’ll find many top-rated and popular tours in the city, offering unique experiences that will inspire you. On this tour, you can go on an epic adventure to some of the best places to visit in Italy. You also get to admire popular places of interest.

You could then travel to Saint Peter's Square for some unforgettable sightseeing experience. This popular attraction is a square and is rated an average of 4.8 out of 5 stars by 38,954 visitors.

This outstanding major basilica has an average rating of 4.8 out of 5 stars by 131,043 travelers.

You’ll have your choice of the best hotels and places to stay in the city of Rome.

After a long day of traveling and sightseeing, we recommend you try one of the best restaurants in the city of Rome, 433. This restaurant has an average rating of 4.4 out of 5 stars by 2,341 customers.

Locals recommend Roma Sparita as one of the best restaurants in the city of Rome. Roma Sparita is rated an average of 4.4 out of 5 stars by 2,073 customers.

After dinner, visit one of the top bars in the city of Rome, D’Angelo Caffè & Gastronomia - Bar Bistro Caffetteria Napoletana a Roma. This popular bar is rated an average of 4.7 out of 5 stars by 1,054 customers.

You could also relax with a drink at a popular bar like Cantina e Cucina. This bar has an average rating of 4.6 out of 5 stars by 7,907 customers.

Ai Tre Scalini is a popular bar that locals recommend in the city of Rome. This bar is rated an average of 4.4 out of 5 stars by 2,950 customers.

Be sure to celebrate another day of your incredible road trip adventure through Italy with a toast!

On day 6 of your road trip across Italy, you’ll have the perfect day exploring the wonderful city of Rome. You’ll stay in Rome for 2 nights, meaning you have plenty of time to discover the best things to see and do in the area.

We recommend you stay at the Grand Hotel Palatino, one of the best 4-star hotels in the city of Rome. This hotel has an average rating of 4.1 out of 5 stars by 4,826 guests.

The best luxury hotel option in the city of Rome is the 5-star NH Collection Roma Palazzo Cinquecento. The hotel is rated an average of 4.3 out of 5 stars by 1,953 guests.

One of the best hotels we recommend in the city of Rome is the 3-star Hotel Nord Nuova Roma. This 3-star hotel has an average rating of 4.2 out of 5 stars by 3,325 guests.

Our flexible booking system will automatically provide you with the best alternatives if these hotels are not available.

You'll have easy access to popular travel destinations in the city of Rome, like the outstanding Castel Sant'Angelo. This attraction has an average rating of 4.7 out of 5 stars by 72,431 visitors and gathers around 918,591 every year.

Piazza Navona is another popular attraction you could visit in the city of Rome. This incredible attraction is a square and has been rated an average of 4.7 out of 5 stars by 158,771 visitors.

One of the best attractions you could visit in the city of Rome is the extraordinary Pantheon. This roman temple gets more than 30,000,000 visitors on an annual basis and is rated an average of 4.8 out of 5 stars in 189,682 reviews.

As the day moves along, one attraction you’ll probably want to visit is the incredible Roman Forum. Around 114,450 visitors have given this square an average rating of 4.7 out of 5 stars.

Today you'll also have the opportunity to spend some time at the fantastic Colosseum. Colosseum is a popular roman amphitheatre, rated an average of 4.7 out of 5 stars by 328,821 travelers. Around 7,400,000 people visit this roman amphitheatre each year.

Come to Rome prepared by adding some tours and tickets to your vacation package. Book a popular and budget-friendly activity you can do on this day in Rome.

After a day of exploring, try one of the best restaurants in the city of Rome.

We recommend you eat at a delicious restaurant that locals enjoy, like Ristorante Amedeo, after your day of exploring the city of Rome. This excellent restaurant has an average rating of 4.3 out of 5 stars by 1,798 customers.

La Taverna dei Fori Imperiali is another of the best restaurants in the city of Rome. This restaurant is rated an average of 4.4 out of 5 stars by 1,637 customers.

Another of the best restaurants in the city of Rome is Maccheroni. The restaurant has an average rating of 4.3 out of 5 stars by 1,633 customers.

Locals recommend VinAllegro, one of the best bars in the city of Rome, for a refreshing evening drink to finish your day. This bar is rated an average of 4.3 out of 5 stars by 1,167 customers.

Alternatively, you could choose another of the most popular bars in the city of Rome, Ristorante Tema. This bar has an average rating of 4.4 out of 5 stars by 939 customers.

Bar Tornatora Rome is also one of the best bars in the city of Rome. This bar is rated an average of 4.3 out of 5 stars by 952 customers.

It's a perfect place to relax and enjoy another amazing evening in Italy.

Day 7 of your road trip will take you to the best attractions Rome has to offer. Cherish the 1 night you have left in Rome by discovering the best things there are to see and do in the city.

There are plenty of attractions, markets, and restaurants for you to experience today in the city of Rome. Your accommodation will be conveniently located close to several of the best attractions you won't want to miss.

You'll be able to visit more of the best travel destinations in the city of Rome, like the extraordinary Villa Borghese. This attraction is an urban zone of rome and has an average rating of 4.6 out of 5 stars by 69,749 visitors.

Another of the best travel destinations in Rome is the spectacular piazza del Popolo. This attraction is a square and is rated an average of 4.6 out of 5 stars by 89,807 visitors.

You could then travel to the amazing Spanish Steps. This monumental staircase has an average rating of 4.5 out of 5 stars by 57,211 visitors.

Piazza di Spagna is another stop you might want to add to your itinerary. This square is a popular destination among visitors in Rome. Rated at an average of 4.7 out of 5 stars by 113,658 visitors, it’s one many travelers find worthy a visit.

If you’re interested in seeing something outstanding today, then consider Trevi Fountain. Trevi Fountain is a sculpture and popular attraction in Rome. More than 343,494 visitors have rated this place an average of 4.8 out of 5 stars.

Your discovery of Rome does not have to stop there. Check out the fantastic selection of tours and tickets offered in Rome on this day of your trip.

After a long day of exploring some of the most popular attractions in Italy, be sure to eat at Coso Ristorante, which is considered one of the best restaurants in the city of Rome. This restaurant is a local favorite and has an average rating of 4.3 out of 5 stars by 1,275 customers.

Alternatively, another of the top restaurants in the city of Rome is the popular Pierluigi. This restaurant is rated an average of 4.3 out of 5 stars by 1,123 customers.

Another great restaurant we recommend in the city of Rome is Ristorante Ad Hoc. This restaurant has an average rating of 4.6 out of 5 stars by 752 customers.

When you’ve finished your meal, La Botticella of Poggi Giovanni is one of the best bars in the city of Rome for an after-dinner drink. This bar has an average rating of 4.7 out of 5 stars by 655 customers.

Tigelleria Romana - Bistrot & Cafè is another of the most popular bars in the city of Rome. This bar is rated an average of 4.3 out of 5 stars by 792 customers.

Alternatively, a great bar that locals enjoy in the city of Rome is La Licata. La Licata has an average rating of 4.5 out of 5 stars by 2,067 customers.

Stopping at one of these popular bars is the perfect way to celebrate another incredible day in the magical city of Rome!

Day 8 of your road trip through Italy gives you the opportunity to experience two places in one day. You'll start your day with some exploring in the city of Rome and end it at a top-rated hotel in the city of Siena. You will stay in Siena for 1 night. Have a hearty breakfast and get excited for a wonderful day ahead!

One of the best places to visit today in Rome is the amazing Altare della Patria. As such, over 1,683,070 people visit Altare della Patria yearly. This attraction is an architectural structure that is rated an average of 4.8 out of 5 stars by 49,843 visitors.

You could also stop at the incredible square, largo di Torre Argentina. With an average rating of 4.5 out of 5 stars by 30,433 visitors, this attraction is one of the top sights in the area.

Another unforgettable travel destination in the Rome is the outstanding Campo de' Fiori. This popular square and travel destination has an average rating of 4.4 out of 5 stars by 51,133 visitors. Approximately 1,683,070 travelers come to Rome every year to see the stunning Altare della Patria with their own eyes.

You can make the most of your new day in Rome by joining activities and tours that let you discover what else the city has in store for you. There are many top-rated experiences you can include in your travel plan to add flavor to your road trip in Italy. Browse all of your options and reserve your slot before it's too late.

At the end of the day, you will drive to the city of Siena, where you will access the best hotels and places to stay.

After a long day of driving and exploring, we recommend you try Osteria degli Svitati, one of the best restaurants in the city of Siena. This restaurant has an average rating of 4.7 out of 5 stars by 911 customers.

Locals also recommend Osteria Il Carroccio as one of the best restaurants in the city of Siena. Osteria Il Carroccio is rated an average of 4.7 out of 5 stars by 895 customers.

Another of the best restaurants in the city of Siena is Antica Trattoria Papei. This restaurant has been rated an average of 4.3 out of 5 stars by 3,761 customers.

After dinner, visit La Taverna di San Giuseppe, which is considered one of the best bars in the city of Siena. This bar is rated an average of 4.7 out of 5 stars by 1,767 customers.

You can also enjoy drinks at a popular bar like Ristorante Gallo Nero. This bar has an average rating of 4.4 out of 5 stars by 829 customers.

Alternatively, San Paolo Pub is one of the best bars that locals recommend in the city of Siena. This bar is rated an average of 4.3 out of 5 stars by 704 customers.

Raise your glass in celebration of your incredible road trip adventure through Italy!

Rise and shine on day 9 of your road trip in Italy. Today, you'll wake up in Siena and embark on a scenic drive to Genoa, where you'll stay at one of the best hotels for 1 night. Seize the opportunity to explore spectacular attractions in Siena and Pisa before you reach your end destination for the day.

It’s hard not to feel excited about visiting attractions in a destination as lovely as Siena. When you’re eager to explore the city and nearby areas, we recommend visiting some local favorites, such as the wonderful piazza del Campo. This attraction is a square that has an average rating of 4.8 out of 5 stars from 64,175 visitors.

You could also stop at the incredible Siena Cathedral. This attraction, a beloved domus, has an average rating of 4.8 out of 5 stars from 21,656 visitors.

If you have time, another site you could explore in Siena is the stunning Fortezza Medicea (Siena). This fortress and travel destination has an average rating of 4.5 out of 5 stars by 9,835 visitors.

Wave goodbye to Pisa and continue your journey by car. If you want to break up today’s drive into two, take the opportunity to stop and discover what the city of Pisa has to offer.

One of the most popular attractions you can visit is the remarkable Leaning Tower of Pisa. This attraction is a bell tower that has an average rating of 4.7 out of 5 stars from 116,882 visitors. Around 3,200,000 people visit Leaning Tower of Pisa every year.

If you want to explore more, visit the incredible Piazza del Duomo, Pisa. This square and attraction has an average rating of 4.7 out of 5 stars from 104,550 reviews.

Another site you could visit today is the top-rated Pisa Cathedral. This cathedral and travel destination is rated an average of 4.8 out of 5 stars by 8,361 visitors.

When you're done with your sightseeing in Pisa, it's time to continue your drive to the city of Genoa. When you arrive in Genoa you’ll check in at one of the best hotels in the area.

We recommend you end the day with a dinner at a popular restaurant near your accommodation, like Zimino. This restaurant offers various delicious and comforting meals and has an average rating of 4.7 out of 5 stars from 733 customers.

Locals also recommend Zeffirino, another of the best restaurants in Genoa. Zeffirino is rated an average of 4.5 out of 5 stars by 705 customers.

If you feel like having something else, check out the menu at RISTORANTE San Giorgio. This restaurant has been rated an average of 4.5 out of 5 stars by 608 customers and is a great place to enjoy a lovely meal.

After dinner, visit Les Rouges Cucina & Cocktails to enjoy a couple of drinks and relax. This bar is one of the best in Genoa, with an average rating of 4.4 out of 5 stars by 928 customers.

You can also enjoy drinks at a popular bar like Bar degli Asinelli. This bar is a great spot to meet new friends and celebrate your vacation. Bar degli Asinelli has an average rating of 4.7 out of 5 stars by 605 customers.

Irish Pub is another bar locals often recommend. This bar offers a great variety of snacks and drinks and is rated an average of 4.3 out of 5 stars by 657 customers.

End your day by raising your glass in celebration of your incredible road trip adventure in Italy, and look forward to more great days to come!

Day 10 of your road trip in Italy is your departure day. This is your chance to catch one last glimpse of Genoa before saying goodbye to this wonderful destination. When you have time to explore the area before you make your way home, we recommend visiting some of the following attractions.

Via Garibaldi is an extraordinary attraction you could visit to enjoy your last day in Genoa. This best-rated sightseeing destination and popular site of interest has an average rating of 4.6 out of 5 stars by 5,399 visitors.

Take a stroll along the main shopping streets of Genoa and find some souvenirs to remind you of your road trip in Italy.

You could then enjoy your last meal in the city of Genoa at La Buca di San Matteo before you travel home. This popular restaurant is rated an average of 4.3 out of 5 stars by 621 customers.

Alternatively, we also recommend Alla Lunga Ristorante for your last chance at a meal in the city of Genoa. The Alla Lunga Ristorante restaurant has an average rating of 4.8 out of 5 stars by 361 customers.

If you'd prefer a popular restaurant that locals enjoy, try Le Mani in Pasta. This restaurant has an average rating of 4.3 out of 5 stars by 537 customers.

You’ll then say farewell to Genoa. We wish you a pleasant journey home, with many wonderful memories of your unforgettable vacation in Italy!