10-Day Italy Self-Drive Road Trip With Itinerary from Genoa traveling east to Florence, Siena, and Rome

On day 2 of your road trip, you will have an entire day to explore Genoa. You’ll stay in Genoa for 2 nights and discover all the best things to see and do in the area.

Genoa is home to plenty of attractions that offer fun adventures, scenic views, and photo-friendly spots! Start at Lighthouse Of Genoa, an intriguing lighthouse that is worthwhile a visit in the city. Nearby, you’ll find Galata Museo Del Mare (complex), enchanting visitors with its eye-catching appeal. Continue your exploration at Aquarium Of Genoa. This aquarium is one of the city’s most impressive spots.

Enjoy the freedom of exploring Genoa at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Porto Antico. After exploring the public square, head to the often recommended Via Garibaldi. Lastly, wrap up today’s self-guided sightseeing tour with a visit to Piazza Della Vittoria, a place of symbolic interest in Genoa.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As dinnertime approaches, it's time to head out for a bite to eat in Genoa. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Treat yourself to a delightful dinner at Zeffirino, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Trattoria Vegia Zena? It's another excellent option with a diverse menu. Consider reserving a table at Trattoria delle Grazie as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Genoa.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

On day 3 of your road trip in Italy, you’ll start and end your day in Genoa, but spend the day exploring what’s beyond the city. Since you will return to Genoa for 1 night more, there’s no need to rush. Experience Riomaggiore, Manarola, and Corniglia to the fullest today with this curated day itinerary!

Brace yourself for today’s incredible lineup of attractions in Genoa, featuring family-friendly attractions, romantic experiences, and natural wonders. Start at Riomaggiore, an intriguing sightseeing destination in the village. Then, head to Manarola Overlook Viewpoint and soak in the ambiance of this majestic observation deck.

There are many interesting places to see in Genoa, and when you are ready for more, go to Cinque Terre National Park. This is one of the village’s most captivating UNESCO world heritage-listed spots of interest.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Genoa.

Indulge in a memorable dining experience at one of Genoa's most popular restaurants, and connect with friendly locals for an authentic adventure.

Don’t miss out on dining at Osteria Sant'Ilario, a top-rated dining destination in Genoa. If you're in the mood to try something new, consider La Cialtroneria, another top spot with a mouthwatering menu. You might also want to secure a reservation at Manhattan Bar. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Genoa this evening.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

Embark on another extraordinary experience on day 4 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Pisa. At the end of the day, you will enjoy the comforts of a top-rated hotel in Florence, which will be your home away from home for 2 nights.

Get ready for a day filled with family-friendly attractions, scenic views, and photo-friendly spots in the charming city of Genoa. Your adventure starts at Knights' Square, an intriguing local hot spot. Another notable attraction to explore is Leaning Tower Of Pisa. This world-famous monument is known for its respected appeal.

After soaking in the highlights of these sights, take some time to wander Genoa's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Pisa Cathedral. This picture-perfect church offers a fascinating experience that many visitors find memorable. Piazza Del Duomo, Pisa is also worth visiting, along with Battistero Di San Giovanni. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at Campo Santo. This up-and-coming cemetery provides a fitting finale to your sightseeing.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Make sure to reserve a table at Ristorante Oliviero 1962, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Di Poneta Novoli, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Caffe San Firenze, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Manifattura, known for its inviting atmosphere. Se·sto On Arno Rooftop Bar is another great option if you’re looking for a place to get the night started. Similarly, Il Vinile provides a great setting to enjoy the night away.

Celebrate another amazing day of your road trip adventure in Italy!

Day 5 offers a multitude of experiences. You will stay in Florence for 1 night more, offering you enough time to explore at a relaxed pace.

Brace yourself for today’s incredible lineup of attractions in Florence, featuring family-friendly attractions, romantic experiences, and breathtaking views. Start at Cathedral Of Santa Maria Del Fiore, a top-rated church in the city. Then, head to Palazzo Vecchio and soak in the ambiance of this history-steeped palace.

There are many interesting places to see in Florence, and when you are ready for more, go to Ponte Vecchio. This is one of the city’s most world-famous romantic spots of interest. After exploring the historical landmark, visit the top-rated Uffizi Gallery. Not far away, you'll also find Basilica Of Santa Croce In Florence. This church is a photogenic highlight in Florence. Before wrapping up your self-guided sightseeing tour, head to Piazzale Michelangelo, a widely recognized observation deck in the city.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a delicious dinner at Ditta Artigianale, an excellent option for tonight's dining. Looking for something different? Trattoria Da Burde offers a tantalizing alternative with its diverse menu. And don’t miss Casa Toscana. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Florence.

After your meal, keep the night alive at a bar like Bar 50 Rosso, known for its lively atmosphere. Bitter Bar is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Archea Brewery offers an excellent atmosphere for those looking to amp up the evening.

Raise your glass to another unforgettable day in Italy!

On day 6 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 2 destinations, Siena and San Gimignano. When you’re not sightseeing, take time to relax at your selected hotel in Siena, where you’ll be staying for 2 nights.

Bring your curiosity for today’s adventure around Florence. Some of the city’s most loved attractions await! Fortezza Medicea (siena) is the perfect place to start. This monument is one of the most worthwhile places to visit in Florence. Next, head to Tower Of Mangia, an increasingly popular monument, known for its culturally significant features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Piazza Del Campo. This history-steeped public square is a highly recommended experience. Nearby, you'll also find Facciatone and Siena Cathedral. Visit these for an interesting touch to your journey. Finish the day with a visit to Piazza Del Duomo, a romantic public square in Florence.

When you’re done exploring for the day, you’ll drive to your hotel in Siena. Check in and spend some time relaxing before you head out to tour the city.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Siena. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Treat yourself to a delightful dinner at Enoteca I Terzi, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Ristorante Tar-Tufo? It's another excellent option with a diverse menu. Consider reserving a table at Antica Trattoria Papei as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Siena.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Meet Life Cafè, a well-loved spot among locals and tourists. Or, head to Maudit Pub. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Bar Impero Siena, another top-rated place in the area.

Head back to your accommodation in Siena and get some rest in preparation for another magical day of your road trip in Italy!

Greet day 7 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Siena for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Montalcino.

Start by visiting Fortress Of Montalcino, a prime spot to begin your journey. This romantic castle is sure to impress. Next on your list is Piazza Del Popolo, another must-visit landmark and curiosity-inducing public square renowned for its romantic features.

While exploring and sightseeing, take time to savor the culture of Siena by sampling some local delicacies. When you’re ready for more sightseeing, head to Church Of Our Lady Of Soccour. This photogenic church is an essential place to visit for anyone looking for the full Siena experience.

When you’re done exploring for the day, you’ll return to Siena and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat in Siena. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a lovely meal at Osteria Quattro Venti, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Fischi per Fiaschi is another top choice with a popular menu. You could also check for a table at Osteria da Divo. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Siena tonight.

Let the evening flow smoothly from dinner to drinks at Charlie Mixology Bar Di Aldinucci Riccardo, a top-rated bar in the area. For other recommendations, Bar Pinacoteca provides a perfect setting for rounding out your night with style and great drinks. Likewise, San Paolo Pub offers a memorable night with diverse drink options and excellent service.

Raise your glass and celebrate another amazing day of your road trip in Italy!

On day 8 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Rome. In the evening, you’ll end up in Rome, where you will stay for 1 night.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Siena allows for both. Start by heading to Colosseum. This wondrous archeological site provides an insightful glimpse into the city's identity. Next, discover Roman Forum, a picture-perfect archeological site, promising a delightful encounter.

Continue your sightseeing with a visit to Trevi Fountain, an iconic monument. When you’re done, don’t forget to make a stop at the world-famous Pantheon. Round off your day at Piazza Navona, another gem in Siena with visually striking features to discover.

At the end of the day, you will drive to Rome, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a lovely meal at La Bottega Roma, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Pasta In Corso is another top choice with a popular menu. You could also check for a table at Trattoria Vecchia Roma. As an establishment that gains consistently high praises from customers, it’s an ideal choice in Rome tonight.

After enjoying a fulfilling meal, continue your evening at La Botticella Of Poggi Giovanni, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, Almalu Trastevere offers a welcoming atmosphere for easing into the nightlife. Similarly, Bar Viminale Di Pepi Maurilio provides an excellent environment for a relaxed and enjoyable evening.

Get a good night's sleep and look forward to another great day on the road in Italy!