10-Day Italy Self-Drive Road Trip With Itinerary from Genoa traveling east to Florence, Siena, and Rome

Day 2 of your road trip will take you to the best attractions Genoa has to offer. Cherish the 2 nights you have left in the city and use the provided itinerary to discover what to see in Genoa.

Enjoy all that Lighthouse Of Genoa has to offer. This is an underrated lighthouse you should not miss. Another must-see is Galata Museo Del Mare (complex), a beloved maritime museum in Genoa.

When you’re ready for the next sight, head to Aquarium Of Genoa. From there, take a leisurely stroll to Porto Antico, another of the city’s interesting attractions. We recommend continuing your self-guided tour at Via Garibaldi, an UNESCO world heritage-designated place of interest in the city. If time allows, add Piazza Della Vittoria to your itinerary. This underrated public square offers the perfect finishing touch to your day in Genoa.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Genoa. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a lovely dining experience at Zeffirino, a popular restaurant in Genoa. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Genoa at Trattoria Vegia Zena, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Trattoria delle Grazie. It’s yet another ideal choice to enhance your time in Genoa tonight.

Take some time to reflect on your day and savor another beautiful night in Italy.

On day 3 of your road trip, you’ll start and end your day in Genoa, where you still have 1 night left. You'll spend part of the day exploring places of interest outside the immediate city, including Riomaggiore, Manarola, and Corniglia.

When you’ve had your share of Genoa, prepare for your next destination. Admire the views and listen to some good music as you drive in the direction of Riomaggiore. Your travel time is around 1 hour 45 min.

Riomaggiore is a worthwhile point of interest we recommend visiting today.

Embrace the thrill of the open road as you wave goodbye to Manarola and set your GPS to Corniglia. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 15 min. Upon reaching Corniglia, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Savor the day by heading to Manarola Overlook Viewpoint, an underrated observation deck that draws visitors from near and far.

Embrace the thrill of the open road as you wave goodbye to Manarola and set your GPS to Corniglia. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 15 min. Upon reaching Corniglia, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Cinque Terre National Park is a popular national park we recommend visiting today. Discover its serene features before continuing your self-guided tour.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Genoa.

After a day of adventure, treat yourself to an exquisite dinner at one of Genoa's best restaurants.

Dine in style at Osteria Sant'Ilario, a top recommendation for dinner tonight. Or, for a change of pace, La Cialtroneria boasts a menu that's sure to impress. Also, be sure to check out Manhattan Bar. Known as a local hotspot, it’s a great choice for tonight in Genoa.

Savor another day of unforgettable experiences in Italy!

Your itinerary for day 4 of your road trip in Italy includes 1 stop and features some of the highlights of Pisa. At the end of the day, enjoy the comforts of a top-rated hotel in Florence, where you'll spend 2 nights.

Embrace the thrill of the open road as you wave goodbye to Genoa and set your GPS to Pisa. While on the road, immerse yourself in your favorite road trip tunes or sample the sounds from a local radio station. This car ride usually takes around 2 hours 5 min. Upon reaching Pisa, unwind, observe, and explore. The best things to do, see, and eat are waiting for you.

Spend your afternoon discovering Knights' Square, a locally appreciated public square known for its breathtaking features. Next, continue your sightseeing at Leaning Tower Of Pisa, a timeless monument.

If you're starting to feel hungry, this is a great time for a break at a nearby restaurant or cafe. When you're ready for more, stop by Pisa Cathedral and uncover the details of this picture-perfect church. Make sure to also explore Piazza Del Duomo, Pisa, a globally renowned public square. For your last stop, consider Battistero Di San Giovanni, a stunning church that many travelers find worth the detour.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy a lovely dining experience at Ristorante Oliviero 1962, a popular restaurant in Florence. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Florence at Di Poneta Novoli, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Caffe San Firenze. It’s yet another ideal choice to enhance your time in Florence tonight.

Continue your evening by exploring the vibrant nightlife scene at Manifattura, a prime destination for a thrilling night out. Also, don’t forget to check out Se·sto On Arno Rooftop Bar, a bar that offers unique local touches. Likewise, Il Vinile provides an excellent alternative for a fun evening.

Raise your glass to another unforgettable day in Italy!

On day 5 of your road trip, you will have an entire day to discover what to see in Florence. You’ll stay in Florence for 1 night.

Cathedral Of Santa Maria Del Fiore is perfect for a self-paced visit during the day. This enchanting church is sure to impress. Next on your list is Palazzo Vecchio, another must-visit landmark and interesting palace renowned for its romantic features.

While exploring and sightseeing, take time to savor the culture of Florence by sampling some local delicacies. When you’re ready for more sightseeing, head to Ponte Vecchio. This visually striking historical landmark is an essential place to visit for anyone looking for the full Florence experience. We also recommend visiting Uffizi Gallery, an extraordinary art gallery. Nearby, you'll also find Basilica Of Santa Croce In Florence, ready to add charm to your journey. End your self-guided sightseeing tour with a stop at Piazzale Michelangelo and wrap up your day with its visually striking appeal.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for a true cultural experience.

Have a fantastic dining experience at Ditta Artigianale, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Trattoria Da Burde offers an enticing alternative with its varied menu. Additionally, Casa Toscana is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

Continue your lively evening at Bar 50 Rosso, a perfect place for winding down or revving up the night, depending on which mood you’re in. Bitter Bar is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Archea Brewery ensures a night out tailored to your taste.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

Dive into day 6 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Siena and San Gimignano. At the end of the day, you’ll unwind at one of the finest accommodations in Siena, where you'll spend 2 nights.

Once you're ready to continue your road trip, it's time to buckle up and drive, eagerly anticipating your arrival in Siena. This drive usually takes around 1 hour 10 min, without any stops or traffic disruptions.

One of our top recommendations for your sightseeing is Fortezza Medicea (siena). Spend some time admiring the historic features of the monument before you continue to your next stop. Then, head to Tower Of Mangia. This locally appreciated monument is a traveler-favorite in the city.

If you're keen to see more, continue to Piazza Del Campo. Feed your curiosity by learning something new about the public square. Next, take your journey to Facciatone, a curiosity-inducing observation deck. Conclude your sightseeing at Siena Cathedral, known for its history-steeped features.

Fasten your seatbelt and make your way to your next stop — San Gimignano, home to many well-known sights in the region. Upon arrival in San Gimignano, we highly recommend checking out some of the top attractions.

Piazza Del Duomo is a worthwhile public square we recommend visiting today. Discover its inviting features before continuing your self-guided tour.

At the end of the day, you will drive to Siena, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Siena. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a lovely meal at Enoteca I Terzi, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Ristorante Tar-Tufo is another top choice with a popular menu. You could also check for a table at Antica Trattoria Papei. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Siena tonight.

Keep the evening going at Meet Life Cafè, a great choice for enjoying the after-dinner hours with a drink. You could also go to Maudit Pub, which offers a similarly pleasant setting and great drinks. Another option is Bar Impero Siena, which provides an inviting environment for unwinding after a busy day out.

Relax and look forward to more memorable moments to come!

On day 7 of your road trip, you’ll start and end your day in Siena, where you have 1 night left to stay.

Whether you decide to explore Montalcino on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss.

Set your GPS to Montalcino and hit the road. Expect a journey of approximately 52 min without stops. Soak in the beautiful landscapes as you drive and look forward to exploring your next destination. Montalcino beckons with new experiences!

When you're ready for some sights, head to Fortress Of Montalcino, a curiosity-inducing castle in Montalcino. Explore its romantic features at your own pace before you continue your journey to your next attraction, Piazza Del Popolo. This curiosity-inducing public square is a top recommendation in the area.

When you’re ready to explore more, Church Of Our Lady Of Soccour is an excellent choice. Spend some time discovering what some claim to be the most stunning church in the region.

When you’re done exploring for the day, you’ll return to Siena and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Siena, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Osteria Quattro Venti, a top-rated dining spot in Siena. If you're in the mood for something new, try Fischi per Fiaschi, another premier location with a delectable menu. You might also want to book a table at Osteria da Divo. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Siena.

Continue your lively evening at Charlie Mixology Bar Di Aldinucci Riccardo, a perfect place for winding down or revving up the night, depending on which mood you’re in. Bar Pinacoteca is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, San Paolo Pub ensures a night out tailored to your taste.

Take some time to reflect on your day and savor another beautiful night in Italy.

Experience an unparalleled adventure on day 8 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 1 place, which are Rome. At the end of the day, you will retreat to the hotel of your choice in Rome, where will spend 1 night.

Continue your road trip and head to your next destination, Rome. This car ride takes around 2 hours 42 min.

Set out on a self-guided sightseeing tour at Colosseum and explore the UNESCO world heritage-listed features. Next, make your way to Roman Forum, another highlight in Rome. When you’re done exploring the archeological site, continue to Trevi Fountain, a romantic monument.

Nearby, you will also find Pantheon. This timeless monument is a top place to see in the area. Lastly, head to Piazza Navona, a grand public square that is perfect for some final exploring in the city.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Rome. Rome offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Rome's best restaurants.

Make sure to reserve a table at La Bottega Roma, an iconic dining spot in Rome. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Pasta In Corso, a popular restaurant in Rome. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Trattoria Vecchia Roma, a hidden gem nestled in Rome. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After your meal, keep the night alive at a bar like La Botticella Of Poggi Giovanni, known for its lively atmosphere. Almalu Trastevere is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Bar Viminale Di Pepi Maurilio offers an excellent atmosphere for those looking to amp up the evening.

Raise your glass and celebrate another amazing day of your road trip in Italy!