10-Day Italy Self-Drive Road Trip With Itinerary from Milan traveling east to Venice, Florence, and La Spezia

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Photo of Arch of Peace, or Arco della Pace, city gate in the centre of the Old Town of Milan in the sunny day, Lombardia, Italy.
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Explore the best of Italy on a 10-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Milan, Lenno, Ossuccio, Verona, Venice, Murano, Florence, Siena, San Gimignano, Pisa, Riomaggiore, La Spezia, Manarola, and Corniglia. This road trip itinerary in Italy seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 4 nights in Milan, 2 nights in Venice, 2 nights in Florence, and 1 night in La Spezia. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Milan, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Piazza San Marco and Rialto Bridge are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Duomo Di Milano Museum, learn more about the unique Verona Arena, and immerse yourself in the vibrant atmosphere of Ponte Vecchio.

As you hit the open road and drive through Milan, Lenno, Ossuccio, Verona, Venice, Murano, Florence, Siena, San Gimignano, Pisa, Riomaggiore, La Spezia, Manarola, and Corniglia, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Corso Vittorio Emanuele II
Sempione ParkCastello SforzescoGalleria Vittorio Emanuele IIDuomo di MilanoBreraNavigli
Villa del BalbianelloVilla CarlottaSacro Monte della Beata Vergine del Soccorso - Ossuccio (co)I Giardini di Villa Melzi
Castelvecchio MuseumCastelvecchio BridgeVerona Arenapiazza delle Erbepiazza dei SignoriPonte Pietra
Bridge of SighsDoge's PalaceSt Mark's BasilicaPiazza San MarcoRialto BridgeMurano
piazzale MichelangeloBasilica of Santa Croce in FlorenceUffizi GalleryPonte VecchioCathedral of Santa Maria del Fiore

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Day 1

Day 1

  • Milan - Arrival day
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  • Corso Vittorio Emanuele II
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Say hello to Milan! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Milan for 3 nights before you continue your adventure!

Milan is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Corso Vittorio Emanuele II, a must-see street, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Milan. Make yourself at home and enjoy some downtime before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Milan, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Hotel Morfeo Milano, a top-rated dining destination in Milan. If you're in the mood to try something new, consider Contraste, another top spot with a mouthwatering menu. You might also want to secure a reservation at UNAHOTELS Galles Milano. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Milan this evening.

Explore the vibrant nightlife at Nottingham Forest after your meal, a hub for lively evenings and memorable moments. Or, head to Armani/bamboo Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Mag Cafe is perfect for those looking to extend their night with a touch of local flavor.

Raise a toast to the start of your 10-day road trip in Italy!

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Day 2

Day 2

  • Milan
  • More

Drive 4 km, 38 min

  • Sempione Park
  • Castello Sforzesco
  • Galleria Vittorio Emanuele II
  • Duomo di Milano
  • Brera
  • Navigli
  • More

Day 2 offers a multitude of experiences. You will stay in Milan for 2 nights more, offering you enough time to explore at a relaxed pace.

Set aside time today to explore Brera, a standout neighborhood that reflects the essence of the city. While you're there, you'll also be within reach of some of the city's top landmarks, making it easy to maximize your day. You might also want to visit Navigli, a neighborhood offering another perspective on the city.

Today’s well-planned self-sightseeing route offers several family-friendly attractions, romantic experiences, and natural wonders. Whether you decide to explore Milan on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Parco Sempione is the first of them. Spend some time admiring this romantic park before continuing your journey. Sforzesco Castle Art Library is your next stop. This extraordinary castle is one of the best-rated sights in Milan.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Galleria Vittorio Emanuele Ii. This history-steeped shopping mall is a sight to behold. To round off your sightseeing experience, visit Duomo Di Milano Museum.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

As you explore more of Milan, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.

Enjoy a delicious meal at Dessert Bar Milano, a top-rated dining destination in Milan. If you're in the mood to try something new, consider Radisson Blu Hotel Milan, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante Qui Si Mangia. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Milan this evening.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Kilburn Cocktail Bar Milano stands out as an excellent choice for a post-dinner cocktail. Alternatively, Bar Frida offers an ideal atmosphere to enjoy the pleasures of the night. The Friends Pub Milano is also a great option that provides a perfect setting for a relaxing evening.

Raise your glass to another unforgettable day in Italy!

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Day 3

Day 3

  • Milan
  • More

Drive 223 km, 4 hours 55 min

  • Villa del Balbianello
  • Villa Carlotta
  • Sacro Monte della Beata Vergine del Soccorso - Ossuccio (co)
  • I Giardini di Villa Melzi
  • More

Wake up to day 3 of your extraordinary road trip in Italy. With 1 night left in Milan, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Brace yourself for today’s incredible lineup of attractions in Milan, featuring family-friendly attractions, romantic experiences, and scenic views. Start at Villa Del Balbianello, a frequently visited villa in the village. Then, head to Villa Carlotta (lake Como) and soak in the ambiance of this awe-inspiring museum.

There are many interesting places to see in Milan, and when you are ready for more, go to Sacro Monte Della Beata Vergine Del Soccorso - Ossuccio (co). This is one of the village’s most increasingly popular history-steeped spots of interest. After exploring the church, visit the beloved I Giardini Di Villa Melzi.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Milan.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Milan. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Make sure to reserve a table at Bice Restaurant, an iconic dining spot in Milan. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Alto Ristorante, a popular restaurant in Milan. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Nero 9, a hidden gem nestled in Milan. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Keep the evening going at Bhangrabar, a great choice for enjoying the after-dinner hours with a drink. You could also go to Rufus Cocktail Bar, which offers a similarly pleasant setting and great drinks. Another option is Ostello Bello Grande, which provides an inviting environment for unwinding after a busy day out.

Raise your glass to another unforgettable day in Italy!

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Day 4

Day 4

  • Milan
  • Venice
  • More

Drive 279 km, 4 hours

  • Castelvecchio Museum
  • Castelvecchio Bridge
  • Verona Arena
  • piazza delle Erbe
  • piazza dei Signori
  • Ponte Pietra
  • More

On day 4 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Verona. In the evening, you’ll end up in Venice, where you will stay for 2 nights.

Today, you'll explore some of the most beautiful places in Milan, including a museum, a monument, a stadium, a public square, a historical landmark and much more! Start your day with a visit to Castelvecchio Museum. This popular museum is a must-visit in the city. When you’re ready for your next discovery, continue to Castelvecchio Bridge, which may be one of the most respected places you will experience today.

One of the best things about exploring Milan on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Verona Arena, a wondrous stadium in the city. If you’re up for more discoveries, don’t forget to reserve some time for Piazza Delle Erbe and Piazza Dei Signori. End your day with a visit to Ponte Pietra, a locally renowned historical landmark that’s sure to leave a lasting impression.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Venice. Venice offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Have a fantastic dining experience at Bauer Hotel, a highly recommended choice for tonight's dinner. If you're looking to mix things up, L'Osteria Le Guglie offers an enticing alternative with its varied menu. Additionally, Corner Pub is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Venice.

After your meal, keep the night alive at a bar like Al Parlamento, known for its lively atmosphere. The Caffe Rosso is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Adagio offers an excellent atmosphere for those looking to amp up the evening.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 5

Day 5

  • Venice
  • More

Drive 15 km, 42 min

  • Bridge of Sighs
  • Doge's Palace
  • St Mark's Basilica
  • Piazza San Marco
  • Rialto Bridge
  • Murano
  • More

Greet day 5 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Venice for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Venice and Murano.

Today’s well-planned self-sightseeing route offers several family-friendly attractions, romantic experiences, and breathtaking views. Whether you decide to explore Venice on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss. Bridge Of Sighs is the first of them. Spend some time admiring this culturally significant monument before continuing your journey. Doge's Palace is your next stop. This interesting palace is one of the best-rated sights in Venice.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit St Mark's Basilica. This UNESCO world heritage-listed church is a sight to behold. To round off your sightseeing experience, visit Piazza San Marco and Rialto Bridge. If time allows, end your day with Murano, a visually striking handicraft store that offers a memorable conclusion to your exploration.

When you’re done exploring for the day, you’ll return to Venice and your accommodation.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Savor the flavors at Generator Venice, a top pick for dinner tonight. Alternatively, Nevodi beckons with its unique menu offerings. Also, consider Ristorante La Piazza. With its consistent customer satisfaction, it’s an excellent option for dining in Venice tonight.

Round off your dining experience by visiting Il Mercante, a prime location for a drink. Alternatively, explore the distinctive characteristics of The Irish Pub Venezia, a bar catering to every mood and preference. Ai Stagneri likewise offers a unique atmosphere, perfect for a memorable night out.

Head back to your accommodation in Venice and get some rest in preparation for another magical day of your road trip in Italy!

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Day 6

Day 6

  • Venice
  • Florence
  • More

Drive 263 km, 3 hours 41 min

  • piazzale Michelangelo
  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • Cathedral of Santa Maria del Fiore
  • More

On day 6 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Florence. When you’re not sightseeing, take time to relax at your selected hotel in Florence, where you’ll be staying for 2 nights.

Today's adventure in Venice promises more breathtaking discoveries and enriching experiences! Begin at Piazzale Michelangelo. This visually striking observation deck is a highlight of any visit in the city. Then, enjoy Basilica Of Santa Croce In Florence, another instagrammable attraction that never fails to captivate visitors. Next, head over to Uffizi Gallery, one of the city’s most astonishing attractions, known for its romantic features.

If you’re looking for more, spend time soaking in the atmosphere of Ponte Vecchio. This romantic historical landmark is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Cathedral Of Santa Maria Del Fiore, a widely recognized church, and take a stroll around the area.

When you’re done exploring for the day, you’ll drive to your hotel in Florence. Check in and spend some time relaxing before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat in Florence. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Ristorante Oliviero 1962, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Di Poneta Novoli, another top spot with a mouthwatering menu. You might also want to secure a reservation at Caffe San Firenze. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

Continue your evening by exploring the vibrant nightlife scene at Manifattura, a prime destination for a thrilling night out. Also, don’t forget to check out Se·sto On Arno Rooftop Bar, a bar that offers unique local touches. Likewise, Il Vinile provides an excellent alternative for a fun evening.

Head back to your accommodation in Florence and get some rest in preparation for another magical day of your road trip in Italy!

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Day 7

Day 7

  • Florence
  • More

Drive 195 km, 3 hours 57 min

  • piazza del Campo
  • Siena Cathedral
  • Santuario di Santa Caterina
  • Fortezza Medicea
  • Porta San Giovanni
  • Villa Calcinaia - Conti Capponi
  • More

On day 7 of your road trip, you’ll start and end your day in Florence, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Siena, San Gimignano, and Greti. You still have 1 night left in Florence.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Florence allows for both. Start by heading to Piazza Del Campo. This astonishing public square provides an insightful glimpse into the city's identity. Next, discover Siena Cathedral, an enchanting church, promising a delightful encounter.

Continue your sightseeing with a visit to Santuario Di Santa Caterina, a frequently visited church. When you’re done, don’t forget to make a stop at the up-and-coming Fortezza Medicea (siena). Not far away from the monument, you will find the visually striking Villa Calcinaia - Conti Capponi, perfect for a quick visit. Round off your day at Porta San Giovanni, another gem in Florence with breathtaking features to discover.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Make sure to reserve a table at Ditta Artigianale, an iconic dining spot in Florence. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Trattoria Da Burde, a popular restaurant in Florence. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Casa Toscana, a hidden gem nestled in Florence. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Explore the vibrant nightlife at Bar 50 Rosso after your meal, a hub for lively evenings and memorable moments. Or, head to Bitter Bar for a great selection of flavorful drinks and a charming setting. Furthermore, Archea Brewery is perfect for those looking to extend their night with a touch of local flavor.

Relax and reminisce about your day in Italy and look forward to more memorable moments to come!

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Day 8

Day 8

  • Florence
  • La Spezia
  • More

Drive 183 km, 3 hours 16 min

  • Cittadella Nuova
  • Knights' Square
  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Pisa Cathedral
  • Santuario di Nostra Signora di Montenero
  • More

Experience an unparalleled adventure on day 8 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Pisa and Riomaggiore. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in La Spezia. You will spend 1 night here for some well-deserved relaxation.

Today’s itinerary in Florence covers several incredible sights, including a park, a public square, a monument, a church and much more! Start your adventure at Cittadella Nuova. This intriguing park is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the culturally significant wonders of Knights' Square, a must-see public square in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Leaning Tower Of Pisa. This iconic monument offers an enriching experience. For a change of pace, head to Piazza Del Duomo, Pisa, where you can take in historic features. Conclude your self-guided sightseeing tour with a visit to Pisa Cathedral and Nostra Signora Di Montenero. These sights offer a fulfilling end to a perfect day.

At the end of the day, you will drive to La Spezia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in La Spezia. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Enjoy a lovely meal at The Colombaio Park, a top-rated place to have dinner tonight.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day 9

Day 9

  • La Spezia
  • Milan
  • More

Drive 267 km, 4 hours 50 min

  • Castle of Riomaggiore
  • Riomaggiore
  • Manarola Overlook Viewpoint
  • Sentiero Azzurro
  • More

Dive into day 9 of your remarkable road trip in Italy. Today you will explore Riomaggiore, Manarola, and Corniglia, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Milan. You’ll stay here for 1 night.

Discover a day packed with family-friendly attractions, romantic experiences, and breathtaking views in La Spezia. Begin your sightseeing with Castle Of Riomaggiore. This underrated castle is one of the top attractions in the village. Proceed to Riomaggiore, another must-visit attraction.

As you wander through the inviting streets of La Spezia, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Manarola Overlook Viewpoint. This worthwhile observation deck is a traveler-favorite. Not far away, you’ll find Sentiero Azzurro, another key site on your sightseeing itinerary.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Milan. Milan offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

Indulge in a memorable dining experience at one of Milan's most popular restaurants, and connect with friendly locals for an authentic adventure.

Savor the flavors at Ristorante la Brisa, a top pick for dinner tonight. Alternatively, Pasticceria San Carlo beckons with its unique menu offerings. Also, consider UNAHOTELS Cusani Milano. With its consistent customer satisfaction, it’s an excellent option for dining in Milan tonight.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Qc Termemilano, a well-loved spot among locals and tourists. Or, head to Yguana Cafè. This bar boasts a welcoming environment that is perfect for winding down.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 10

Day 10

  • Milan - Departure day
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  • Pinacoteca di Brera
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Milan before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Pinacoteca Di Brera. This well-known art gallery is a popular place to see in the city.

Make the most of your final day in Italy by visiting Milan’s iconic markets and shopping establishments in the buzzing Galleria Vittorio Emanuele II. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing experience in Italy. Elevate your style with pieces from high-end retail stores.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Milan.

Dine in style at Vento di Sardegna, a top recommendation for dinner tonight. Or, for a change of pace, Palazzo Parigi Hotel & Grand Spa Milano boasts a menu that's sure to impress.

You’ll then say farewell to Milan. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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