10-Day Italy Self-Drive Road Trip With Itinerary from Milan traveling east to Venice, Florence, and La Spezia

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Photo of Arch of Peace, or Arco della Pace, city gate in the centre of the Old Town of Milan in the sunny day, Lombardia, Italy.
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Explore the best of Italy on a remarkable 10-day road trip! Combine exploration with relaxation on a self-drive tour featuring Milan, Lenno, Ossuccio, Verona, Venice, Murano, Florence, Siena, San Gimignano, Pisa, Riomaggiore, La Spezia, Manarola, and Corniglia.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 4 nights in Milan, 2 nights in Venice, 2 nights in Florence, and 1 night in La Spezia. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Milan, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Piazza San Marco and Rialto Bridge are just a couple of the bucket-list attractions that await your discovery.

As you hit the open road and drive through Milan, Lenno, Ossuccio, Verona, Venice, Murano, Florence, Siena, San Gimignano, Pisa, Riomaggiore, La Spezia, Manarola, and Corniglia, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Pick-up: 10:00
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Day1

Day 1

  • Milan - Arrival day
  • More
  • Corso Vittorio Emanuele II
  • More

Say hello to Milan! Your exciting road trip through Italy is just about to start. Navigating the top places to see in the region is a breeze with a car. The rental vehicle of your choice will be ready for pickup upon your arrival in the city. You will stay in Milan for 3 nights before you continue your adventure!

Milan is a beautiful city with plenty to discover. Taking a stroll in the city center is a great alternative. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

As afternoon approaches, head to your chosen hotel in Milan. Check-in typically starts around 2 to 4 PM at hotels in Italy. We recommend staying at a central location for easy access to key areas in the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Milan, it's often a good idea to reserve a table in advance.

Treat yourself to a wonderful meal at Hotel Morfeo Milano, a top-rated dining spot in Milan. If you're in the mood for something new, try Contraste, another premier location with a delectable menu. You might also want to book a table at UNAHOTELS Galles Milano. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Milan.

If you’re not ready to end the night just yet, Nottingham Forest offers a perfect venue to relax and savor a drink. Similarly, Armani/bamboo Bar is well-suited for those looking to unwind in a social setting. Mag Cafe is another excellent spot to enjoy a nightcap after a delightful meal.

Raise a toast to the start of your 10-day road trip in Italy!

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Day2

Day 2

  • Milan
  • More

Drive 4 km, 38 min

  • Sempione Park
  • Castello Sforzesco
  • Galleria Vittorio Emanuele II
  • Duomo di Milano
  • Brera
  • Navigli
  • More

On day 2 of your road trip, you will have an entire day to discover what to see in Milan. You’ll stay in Milan for 2 nights.

A visit to Brera is a must on the agenda today. This neighborhood is full of hidden gems and character, perfect for a leisurely stroll. Plus, you’ll be close to some of the city’s most famous sights. Don’t forget to check out Navigli as well, a neighborhood that adds another layer to your exploration.

Enjoy all that Parco Sempione has to offer. This is an impressive park you should not miss. Another must-see is Sforzesco Castle Art Library, a spectacular castle in Milan.

When you’re ready for the next sight, head to Galleria Vittorio Emanuele Ii. From there, take a leisurely stroll to Duomo Di Milano Museum, another of the city’s iconic attractions.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Milan's best restaurants.

Don’t miss out on dining at Dessert Bar Milano, a top-rated dining destination in Milan. If you're in the mood to try something new, consider Radisson Blu Hotel Milan, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante Qui Si Mangia. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Milan this evening.

Keep the excitement of the evening going by visiting a bar or two. Kilburn Cocktail Bar Milano is an excellent place to start. You could also check out Bar Frida, offering a different kind of charm. A last recommendation for the day is The Friends Pub Milano. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in Italy.

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Day3

Day 3

  • Milan
  • More

Drive 223 km, 4 hours 55 min

  • Villa del Balbianello
  • Villa Carlotta
  • Sacro Monte della Beata Vergine del Soccorso - Ossuccio (co)
  • I Giardini di Villa Melzi
  • More

Wake up to day 3 of your road trip in Italy. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Lenno, Rogaro, Ossuccio, and Loppia. With 1 night to stay in Milan, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

Let Villa Del Balbianello set the tone for the day. Villa Carlotta (lake Como) is your next stop. This locally appreciated museum is one of the best-rated sights in Milan.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit Sacro Monte Della Beata Vergine Del Soccorso - Ossuccio (co). This romantic church is a sight to behold. To round off your sightseeing experience, visit I Giardini Di Villa Melzi.

When you’re done exploring for the day, you’ll return to Milan and your accommodation.

Milan is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Milan.

Don’t miss out on dining at Bice Restaurant, a top-rated dining destination in Milan. If you're in the mood to try something new, consider Alto Ristorante, another top spot with a mouthwatering menu. You might also want to secure a reservation at Nero 9. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Milan this evening.

Extend your evening after a delightful meal by visiting Bhangrabar, which offers the perfect atmosphere for a night out. Moreover, Rufus Cocktail Bar is another popular option for a drink or two. Likewise, Ostello Bello Grande also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Raise your glass and celebrate another amazing day of your road trip in Italy!

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Day4

Day 4

  • Milan
  • Venice
  • More

Drive 279 km, 4 hours

  • Castelvecchio Museum
  • Castelvecchio Bridge
  • Verona Arena
  • piazza delle Erbe
  • piazza dei Signori
  • Ponte Pietra
  • More

Your itinerary for day 4 of your road trip in Italy includes 1 stop and features some of the highlights of Verona. At the end of the day, enjoy the comforts of a top-rated hotel in Venice, where you'll spend 2 nights.

Visiting Castelvecchio Museum is always a good idea. This captivating museum is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the enchanting wonders of Castelvecchio Bridge, a must-see monument in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Verona Arena. This world-famous stadium offers an enriching experience. For a change of pace, head to Piazza Delle Erbe, where you can take in awe-inspiring features. Conclude your self-guided sightseeing tour with a visit to Piazza Dei Signori and Ponte Pietra These sights offer a fulfilling end to a perfect day.

When you’re done exploring for the day, you’ll drive to your hotel in Venice. Check in and relax before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delightful dinner at Bauer Hotel, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try L'Osteria Le Guglie? It's another excellent option with a diverse menu. Consider reserving a table at Corner Pub as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Venice.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Al Parlamento stands out as an excellent choice for a post-dinner cocktail. Alternatively, The Caffe Rosso offers an ideal atmosphere to enjoy the pleasures of the night. Adagio is also a great option that provides a perfect setting for a relaxing evening.

Relax and look forward to more memorable moments to come!

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Day5

Day 5

  • Venice
  • More

Drive 15 km, 42 min

  • Bridge of Sighs
  • Doge's Palace
  • St Mark's Basilica
  • Piazza San Marco
  • Rialto Bridge
  • Murano
  • More

On day 5 of your road trip in Italy, you’ll start and end your day in Venice, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Venice, there’s no need to rush. Experience Venice and Murano to the fullest today with this curated day itinerary.

Awaiting your discovery is the captivating Bridge Of Sighs, a grand monument in Venice. Next, go to Doge's Palace.

After visiting Bridge Of Sighs and Doge's Palace, have a stroll along Venice's streets and take in the local charm. Continue your sightseeing by heading to St Mark's Basilica. This inviting church offers a unique experience. Piazza San Marco is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Rialto Bridge, one of the most symbolic places to visit in Venice. If you still have some time left for sightseeing, we also recommend stopping by Murano.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Venice.

Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a delightful dinner at Generator Venice, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Nevodi? It's another excellent option with a diverse menu. Consider reserving a table at Ristorante La Piazza as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Venice.

After enjoying a fulfilling meal, continue your evening at Il Mercante, ideal for those looking to unwind with a drink in a comfortable setting. Alternatively, The Irish Pub Venezia offers a welcoming atmosphere for easing into the nightlife. Similarly, Ai Stagneri provides an excellent environment for a relaxed and enjoyable evening.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day6

Day 6

  • Venice
  • Florence
  • More

Drive 263 km, 3 hours 41 min

  • piazzale Michelangelo
  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • Cathedral of Santa Maria del Fiore
  • More

On day 6 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Florence are on today's agenda. In the evening, you’ll end up in Florence, where you will stay for 2 nights.

Piazzale Michelangelo is must-visit observation deck and a great option for a daytime tour of the area. Continue your journey to Basilica Of Santa Croce In Florence, a popular church, located just a leisurely stroll away. Next, head to Uffizi Gallery, a romantic art gallery, also available for your discovery today.

Each stop on today’s itinerary promises to leave you with lasting memories and a deeper appreciation for Venice. When you're ready, let your sightseeing route take you to the iconic Ponte Vecchio. If you’re looking for more, Cathedral Of Santa Maria Del Fiore is also a widely recognized attraction that is worthwhile a visit.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Treat yourself to a delicious dinner at Ristorante Oliviero 1962, an excellent option for tonight's dining. Looking for something different? Di Poneta Novoli offers a tantalizing alternative with its diverse menu. And don’t miss Caffe San Firenze. Known for great service, it’s a fantastic choice for tonight in Florence.

Continue your lively evening at Manifattura, a perfect place for winding down or revving up the night, depending on which mood you’re in. Se·sto On Arno Rooftop Bar is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Il Vinile ensures a night out tailored to your taste.

Celebrate another amazing day of your road trip adventure in Italy!

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Day7

Day 7

  • Florence
  • More

Drive 195 km, 3 hours 57 min

  • piazza del Campo
  • Siena Cathedral
  • Santuario di Santa Caterina
  • Fortezza Medicea
  • Porta San Giovanni
  • Villa Calcinaia - Conti Capponi
  • More

On day 7 of your road trip, you’ll start and end your day in Florence, where you have 1 night left to stay.

Whether you decide to explore Siena on foot, use public transport, or join a guided tour, there are a few attractions you don’t want to miss.

Piazza Del Campo is perfect for a self-paced visit during the day. This respected public square is sure to impress. Next on your list is Siena Cathedral, another must-visit landmark and captivating church renowned for its inviting features.

While exploring and sightseeing, take time to savor the culture of Florence by sampling some local delicacies. When you’re ready for more sightseeing, head to Santuario Di Santa Caterina. This heritage-rich church is an essential place to visit for anyone looking for the full Florence experience. We also recommend visiting Fortezza Medicea (siena), an up-and-coming monument. Nearby, you'll also find Porta San Giovanni, ready to add charm to your journey. End your self-guided sightseeing tour with a stop at Villa Calcinaia - Conti Capponi and wrap up your day with its romantic appeal.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Florence. Enjoy a relaxing evening as you savor delicious local cuisine.

Have a fantastic dining experience at Ditta Artigianale, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Trattoria Da Burde offers an enticing alternative with its varied menu. Additionally, Casa Toscana is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Florence.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Bar 50 Rosso, a well-loved spot among locals and tourists. Or, head to Bitter Bar. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Archea Brewery, another top-rated place in the area.

Head back to your accommodation in Florence and get some rest to prepare for another magical day of your road trip in Italy.

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Day8

Day 8

  • Florence
  • La Spezia
  • More

Drive 183 km, 3 hours 16 min

  • Cittadella Nuova
  • Knights' Square
  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Pisa Cathedral
  • Santuario di Nostra Signora di Montenero
  • More

Dive into day 8 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Pisa and Riomaggiore. At the end of the day, you’ll unwind at one of the finest accommodations in La Spezia, where you'll spend 1 night.

Your adventure in Florence is only getting started when you visit Cittadella Nuova, an often recommended local hot spot. Another notable attraction to explore is Knights' Square. This beloved public square is known for its visually striking appeal.

After soaking in the highlights of these sights, take some time to wander Florence's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Leaning Tower Of Pisa. This remarkable monument offers a fascinating experience that many visitors find memorable. Piazza Del Duomo, Pisa is also worth visiting, along with Pisa Cathedral. These standout landmarks offer unique experiences that add to the day’s enjoyment. End your day at Nostra Signora Di Montenero. This frequently visited church provides a fitting finale to your sightseeing.

At the end of the day, you will drive to La Spezia, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of La Spezia's most popular restaurants, and connect with friendly locals for a true cultural experience.

Enjoy a lovely dining experience at The Colombaio Park, a popular restaurant in La Spezia. This acclaimed establishment has earned the admiration of countless food lovers in the city.

Relax and recharge in preparation for another adventurous day in Italy!

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Day9

Day 9

  • La Spezia
  • Milan
  • More

Drive 267 km, 4 hours 50 min

  • Castle of Riomaggiore
  • Riomaggiore
  • Manarola Overlook Viewpoint
  • Sentiero Azzurro
  • More

Experience an unparalleled adventure on day 9 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 3 places, which are Riomaggiore, Manarola, and Corniglia. At the end of the day, you will retreat to the hotel of your choice in Milan, where will spend 1 night.

To truly experience La Spezia, make sure to drop by Castle Of Riomaggiore. This intriguing castle is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Riomaggiore, one of the village’s best highlights.

Next, check out Manarola Overlook Viewpoint, one of the most underrated places to see in La Spezia. This observation deck is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, Sentiero Azzurro. Wander around and soak in the romantic atmosphere this hiking area offers.

When you’re done exploring for the day, you’ll drive to your hotel in Milan. Check in and relax before you head out to tour the city.

Milan is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Milan.

Don’t miss out on dining at Ristorante la Brisa, a top-rated dining destination in Milan. If you're in the mood to try something new, consider Pasticceria San Carlo, another top spot with a mouthwatering menu. You might also want to secure a reservation at UNAHOTELS Cusani Milano. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Milan this evening.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Qc Termemilano, a well-loved spot among locals and tourists. Or, head to Yguana Cafè. This bar boasts a welcoming environment that is perfect for winding down.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day10

Day 10

  • Milan - Departure day
  • More
  • Pinacoteca di Brera
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Milan before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Pinacoteca Di Brera, a photogenic art gallery before you head out.

Make the most of your final day in Italy by visiting Milan’s iconic markets and shopping establishments in the buzzing Via della Moscova. Secure the perfect souvenirs for your family and friends back home or buy yourself a remembrance of your amazing vacation. You can also browse through boutiques for stylish fashion choices. Savor your final moments in Italy at a cozy cafe while relaxing with a cup of coffee or tea.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Milan.

If you're in the mood to try something new, consider Palazzo Parigi Hotel & Grand Spa Milano, another top spot with a mouthwatering menu.

You’ll then say farewell to Milan. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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