10-Day Italy Self-Drive Road Trip With Itinerary from Milan traveling east to Venice, Florence, and La Spezia
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Explore the best of Italy on a 10-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Milan, Lenno, Ossuccio, Verona, Venice, Murano, Florence, Siena, San Gimignano, Pisa, Riomaggiore, La Spezia, Manarola, and Corniglia. This road trip itinerary in Italy seamlessly combines exploration with relaxation.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 4 nights in Milan, 2 nights in Venice, 2 nights in Florence, and 1 night in La Spezia. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Milan, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Piazza San Marco and Rialto Bridge are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Duomo Di Milano Museum, learn more about the unique Verona Arena, and immerse yourself in the vibrant atmosphere of Ponte Vecchio.
As you hit the open road and drive through Milan, Lenno, Ossuccio, Verona, Venice, Murano, Florence, Siena, San Gimignano, Pisa, Riomaggiore, La Spezia, Manarola, and Corniglia, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
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Day 1
- Milan - Arrival day
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- Corso Vittorio Emanuele II
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Welcome to Milan, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 3 nights immersing yourself in Milan's charm before embarking on the next leg of your journey.
Milan is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Corso Vittorio Emanuele II, a must-see street, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Find your way to your hotel in Milan. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Milan, it's often a good idea to reserve a table in advance.
Don’t miss out on dining at Hotel Morfeo Milano, a top-rated dining destination in Milan. If you're in the mood to try something new, consider Contraste, another top spot with a mouthwatering menu. You might also want to secure a reservation at UNAHOTELS Galles Milano. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Milan this evening.
Keep the excitement of the evening going by visiting a bar or two. Nottingham Forest is an excellent place to start. You could also check out Armani/bamboo Bar, offering a different kind of charm. A last recommendation for the day is Mag Cafe. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.
Raise a toast to the start of your 10-day road trip in Italy!
Day 2
- Milan
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Drive 4 km, 38 min
- Sempione Park
- Castello Sforzesco
- Galleria Vittorio Emanuele II
- Duomo di Milano
- Brera
- Navigli
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Day 2 of your road trip across Italy promises a magnificent time exploring Milan. You have 2 nights left in Milan. Take the opportunity to experience more of the best attractions and activities in the city.
Brera is one of the highlights of today. Take your time exploring this iconic neighborhood in Milan, which offers a perfect blend of history and culture. Plus, it's close to many must-see landmarks in the city. Be sure to also visit Navigli, a neighborhood that showcases another side of Milan.
Today, you'll explore some of the most beautiful places in Milan, including a park, a castle, a shopping mall, a church and much more! Start your day with a visit to Parco Sempione. This impressive park is a must-visit in the city. When you’re ready for your next discovery, continue to Sforzesco Castle Art Library, which may be one of the most culturally significant places you will experience today.
One of the best things about exploring Milan on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Galleria Vittorio Emanuele Ii, a top-rated shopping mall in the city. If you’re up for more discoveries, don’t forget to reserve some time for Duomo Di Milano Museum.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Milan. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Treat yourself to a delicious dinner at Dessert Bar Milano, an excellent option for tonight's dining. Looking for something different? Radisson Blu Hotel Milan offers a tantalizing alternative with its diverse menu. And don’t miss Ristorante Qui Si Mangia. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Milan.
Round off your dining experience by visiting Kilburn Cocktail Bar Milano, a prime location for a drink. Alternatively, explore the distinctive characteristics of Bar Frida, a bar catering to every mood and preference. The Friends Pub Milano likewise offers a unique atmosphere, perfect for a memorable night out.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 3
- Milan
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Drive 223 km, 4 hours 55 min
- Villa del Balbianello
- Villa Carlotta
- Sacro Monte della Beata Vergine del Soccorso - Ossuccio (co)
- I Giardini di Villa Melzi
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Wake up to day 3 of your extraordinary road trip in Italy. With 1 night left in Milan, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!
Prepare for a day full of family-friendly attractions, romantic experiences, and breathtaking views. When you’re ready, kick off your sightseeing adventure at Villa Del Balbianello. This frequently visited villa is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Villa Carlotta (lake Como), one of the village’s best highlights.
Next, check out Sacro Monte Della Beata Vergine Del Soccorso - Ossuccio (co), one of the most frequently visited places to see in Milan. This church is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, I Giardini Di Villa Melzi. Wander around and soak in the serene atmosphere this botanical garden offers.
When you’re done exploring for the day, you’ll return to Milan and your accommodation.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Milan. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Enjoy a lovely dining experience at Bice Restaurant, a popular restaurant in Milan. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Milan at Alto Ristorante, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Nero 9. It’s yet another ideal choice to enhance your time in Milan tonight.
Continue your lively evening at Bhangrabar, a perfect place for winding down or revving up the night, depending on which mood you’re in. Rufus Cocktail Bar is another excellent bar that offers a great selection of drinks to suit any mood. If you prefer to go somewhere else, Ostello Bello Grande ensures a night out tailored to your taste.
Celebrate another amazing day of your road trip adventure in Italy!
Day 4
- Milan
- Venice
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Drive 279 km, 4 hours
- Castelvecchio Museum
- Castelvecchio Bridge
- Verona Arena
- piazza delle Erbe
- piazza dei Signori
- Ponte Pietra
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Dive into day 4 of your remarkable road trip in Italy. Today you will explore Verona, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Venice. You’ll stay here for 2 nights.
Set out on a day brimming with fun adventures, breathtaking views, and photo-friendly spots. Start at the locally renowned Castelvecchio Museum, a historic museum in Milan. Next, go to Castelvecchio Bridge.
After visiting Castelvecchio Museum and Castelvecchio Bridge, have a stroll along Milan's streets and take in the local charm. Continue your sightseeing by heading to Verona Arena. This visually striking stadium offers a unique experience. Piazza Delle Erbe is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Piazza Dei Signori, one of the most grand places to visit in Milan. If you still have some time left for sightseeing, we also recommend stopping by Ponte Pietra.
At the end of the day, you will drive to Venice, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Venice. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Treat yourself to a wonderful meal at Bauer Hotel, a top-rated dining spot in Venice. If you're in the mood for something new, try L'Osteria Le Guglie, another premier location with a delectable menu. You might also want to book a table at Corner Pub. Known for its consistently satisfied patrons, it’s a perfect choice to elevate your evening in Venice.
Explore the vibrant nightlife at Al Parlamento after your meal, a hub for lively evenings and memorable moments. Or, head to The Caffe Rosso for a great selection of flavorful drinks and a charming setting. Furthermore, Adagio is perfect for those looking to extend their night with a touch of local flavor.
Head back to your accommodation in Venice and get some rest in preparation for another magical day of your road trip in Italy!
Day 5
- Venice
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Drive 15 km, 42 min
- Bridge of Sighs
- Doge's Palace
- St Mark's Basilica
- Piazza San Marco
- Rialto Bridge
- Murano
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On day 5 of your road trip, you’ll start and end your day in Venice, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Venice and Murano. You still have 1 night left in Venice.
Savor the day by visiting some of the best places to see in Venice, including a monument, a palace, a church, a public square, a historical landmark, a handicraft store and much more! Start your adventure at Bridge Of Sighs. This locally renowned monument is a must-visit for travelers looking for a unique holiday experience. Make your way to Doge's Palace located in Venice for another exciting encounter.
Next, immerse yourself in the setting of St Mark's Basilica. Its UNESCO world heritage-listed features will captivate you. After the church, continue your tour of the city with a visit to Piazza San Marco. Visitors usually appreciate the romantic features of this public square. Next up is Rialto Bridge, a highly recommended historical landmark. For a change of pace, head to Murano. As one of the most frequently visited attractions in Venice, this handicraft store is the perfect place to end your self-guided sightseeing tour.
When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Venice.
After a day of adventure, treat yourself to an exquisite dinner at one of Venice's best restaurants.
Enjoy a delicious meal at Generator Venice, a highly-rated dining destination in Venice. If you're eager to try something different, consider Nevodi, another top spot with a tantalizing menu. You might also want to secure a reservation at Ristorante La Piazza. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Venice this evening.
Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Il Mercante stands out as an excellent choice for a post-dinner cocktail. Alternatively, The Irish Pub Venezia offers an ideal atmosphere to enjoy the pleasures of the night. Ai Stagneri is also a great option that provides a perfect setting for a relaxing evening.
As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.
Day 6
- Venice
- Florence
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Drive 263 km, 3 hours 41 min
- piazzale Michelangelo
- Basilica of Santa Croce in Florence
- Uffizi Gallery
- Ponte Vecchio
- Cathedral of Santa Maria del Fiore
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On day 6 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Florence. In the evening, you’ll end up in Florence, where you will stay for 2 nights.
Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Venice allows for both. Start by heading to Piazzale Michelangelo. This widely recognized observation deck provides an insightful glimpse into the city's identity. Next, discover Basilica Of Santa Croce In Florence, a monumental church, promising a delightful encounter.
Continue your sightseeing with a visit to Uffizi Gallery, a spectacular art gallery. When you’re done, don’t forget to make a stop at the timeless Ponte Vecchio. Round off your day at Cathedral Of Santa Maria Del Fiore, another gem in Venice with romantic features to discover.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.
Savor the flavors at Ristorante Oliviero 1962, a top pick for dinner tonight. Alternatively, Di Poneta Novoli beckons with its unique menu offerings. Also, consider Caffe San Firenze. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.
After savoring a delicious meal, step into the vibrant nightlife at Manifattura, where the evening is just getting started. In the same way, Se·sto On Arno Rooftop Bar offers a unique charm perfect for experiencing the local bar scene in Florence. Il Vinile is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.
Celebrate another amazing day of your road trip adventure in Italy!
Day 7
- Florence
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Drive 195 km, 3 hours 57 min
- piazza del Campo
- Siena Cathedral
- Santuario di Santa Caterina
- Fortezza Medicea
- Porta San Giovanni
- Villa Calcinaia - Conti Capponi
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Greet day 7 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Florence for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Siena, San Gimignano, and Greti.
Discover a day packed with fun adventures, romantic experiences, and scenic views in Florence. Begin your sightseeing with Piazza Del Campo. This widely recognized public square is one of the top attractions in the city. Proceed to Siena Cathedral, another must-visit attraction.
As you wander through the inviting streets of Florence, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Santuario Di Santa Caterina. This curiosity-inducing church is a traveler-favorite. Not far away, you’ll find Fortezza Medicea (siena), another key site on your sightseeing itinerary. Porta San Giovanni is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers. Conclude your day at Villa Calcinaia - Conti Capponi and uncover why it's recognized as one of the city's most increasingly popular attractions.
When you’re done exploring for the day, you’ll return to Florence and your accommodation.
As you explore more of Florence, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Treat yourself to a delightful dinner at Ditta Artigianale, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Trattoria Da Burde? It's another excellent option with a diverse menu. Consider reserving a table at Casa Toscana as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Florence.
Extend your evening after a delightful meal by visiting Bar 50 Rosso, which offers the perfect atmosphere for a night out. Moreover, Bitter Bar is another popular option for a drink or two. Likewise, Archea Brewery also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.
Take some time to reflect on your day and savor another beautiful night in Italy.
Day 8
- Florence
- La Spezia
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Drive 183 km, 3 hours 16 min
- Cittadella Nuova
- Knights' Square
- Leaning Tower of Pisa
- Piazza del Duomo, Pisa
- Pisa Cathedral
- Santuario di Nostra Signora di Montenero
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Experience an unparalleled adventure on day 8 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Pisa and Riomaggiore. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in La Spezia. You will spend 1 night here for some well-deserved relaxation.
A blend of fun adventures, romantic experiences, and breathtaking views await you in Florence on today’s itinerary. First up is the intriguing park, Cittadella Nuova. Afterward, continue to Knights' Square, a public square every traveler should visit.
As you explore Florence’s charming streets, take in the lively atmosphere and get to know the character of the city. Next, make your way to Leaning Tower Of Pisa. This globally renowned monument is an essential stop. Following that, head to Piazza Del Duomo, Pisa, another must-visit site that will enhance your experience. Don’t forget to stop by Pisa Cathedral, a beloved church in the city. Finally, end your day with a visit to Nostra Signora Di Montenero, an enchanting church that offers the perfect conclusion to your sightseeing of the day.
When you’re done exploring for the day, you’ll drive to your hotel in La Spezia. Check in and spend some time relaxing before you head out to tour the city.
Indulge in a memorable dining experience at one of La Spezia's most popular restaurants, and connect with friendly locals for an authentic adventure.
Don’t miss out on dining at The Colombaio Park, a top-rated dining destination in La Spezia.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 9
- La Spezia
- Milan
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Drive 267 km, 4 hours 50 min
- Castle of Riomaggiore
- Riomaggiore
- Manarola Overlook Viewpoint
- Sentiero Azzurro
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On day 9 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 3 destinations, Riomaggiore, Manarola, and Corniglia. When you’re not sightseeing, take time to relax at your selected hotel in Milan, where you’ll be staying for 1 night.
Start your adventure at Castle Of Riomaggiore. This frequently visited castle is a must-visit for travelers looking for a unique holiday experience. Make your way to Riomaggiore located in La Spezia for another exciting encounter.
Next, immerse yourself in the setting of Manarola Overlook Viewpoint. Its majestic features will captivate you. After the observation deck, continue your tour of the village with a visit to Sentiero Azzurro. Visitors usually appreciate the serene features of this hiking area.
At the end of the day, you will drive to Milan, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
As you explore more of Milan, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Enjoy a lovely dining experience at Ristorante la Brisa, a popular restaurant in Milan. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Milan at Pasticceria San Carlo, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated UNAHOTELS Cusani Milano. It’s yet another ideal choice to enhance your time in Milan tonight.
To truly maximize your evening out, consider visiting Qc Termemilano after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Yguana Cafè, another bar with an inviting ambiance.
Raise your glass to another unforgettable day in Italy!
Day 10
- Milan - Departure day
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- Pinacoteca di Brera
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Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Milan before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, we recommend visiting Pinacoteca Di Brera, a heritage-rich art gallery before you head out.
Maximize your last day in Italy and go on a shopping spree in Milan’s shopping center, the lively Quadrilatero della Moda. Browse for souvenirs to remind you of your wonderful journey in Italy. Discover boutiques with stylish fashion choices to upgrade your wardrobe. You can also explore high-end shops for luxury items.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Milan.
Treat yourself to a delightful dinner at Vento di Sardegna, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Palazzo Parigi Hotel & Grand Spa Milano? It's another excellent option with a diverse menu.
You’ll then say farewell to Milan. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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