10-Day Italy Self-Drive Road Trip With Itinerary from Milan traveling east to Venice, Florence, and La Spezia

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Photo of Arch of Peace, or Arco della Pace, city gate in the centre of the Old Town of Milan in the sunny day, Lombardia, Italy.
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Experience the freedom of the open road on an unforgettable 10-day road trip in Italy! Embark on a self-drive tour that caters to every traveler, featuring destinations like Milan, Lenno, Ossuccio, Verona, Venice, Murano, Florence, Siena, San Gimignano, Pisa, Riomaggiore, La Spezia, Manarola, and Corniglia.

This perfectly planned road trip itinerary takes you through some of the best places to see in Italy. You will spend 4 nights in Milan, 2 nights in Venice, 2 nights in Florence, and 1 night in La Spezia. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have you covered.

Upon arriving in Milan, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Piazza San Marco and Rialto Bridge are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Duomo Di Milano Museum, learn more about the unique Verona Arena, and immerse yourself in the vibrant atmosphere of Ponte Vecchio.

As you hit the open road and drive through Milan, Lenno, Ossuccio, Verona, Venice, Murano, Florence, Siena, San Gimignano, Pisa, Riomaggiore, La Spezia, Manarola, and Corniglia, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodations, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Day 1

Day 1

  • Milan - Arrival day
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  • Corso Vittorio Emanuele II
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Welcome to Milan, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 3 nights discovering what to see in Milan before embarking on the next leg of your journey.

Milan is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Corso Vittorio Emanuele II, a must-see street, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

When you're ready for some downtime, make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Milan. Make yourself at home and unwind before heading out again.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Milan, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Hotel Morfeo Milano, a top-rated dining destination in Milan. If you're in the mood to try something new, consider Contraste, another top spot with a mouthwatering menu. You might also want to secure a reservation at UNAHOTELS Galles Milano. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Milan this evening.

Keep the excitement of the evening going by visiting a bar or two. Nottingham Forest is an excellent place to start. You could also check out Armani/bamboo Bar, offering a different kind of charm. A last recommendation for the day is Mag Cafe. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

Raise a toast to the start of your 10-day road trip in Italy!

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Day 2

Day 2

  • Milan
  • More

Drive 4 km, 38 min

  • Sempione Park
  • Castello Sforzesco
  • Galleria Vittorio Emanuele II
  • Duomo di Milano
  • Brera
  • Navigli
  • More

Day 2 of your road trip across Italy promises a magnificent time exploring what to see in Milan. You have 2 nights left in Milan. Take the opportunity to experience more of the best attractions and activities in the city.

Brera is one of the highlights of today. Take your time exploring this iconic neighborhood in Milan, which offers a perfect blend of history and culture. Plus, it's close to many must-see landmarks in the city. Be sure to also visit Navigli, a neighborhood that showcases another side of Milan.

Parco Sempione is an ideal stop early in the day. This widely recognized park is a must-visit in the city. When you’re ready for your next discovery, continue to Sforzesco Castle Art Library, which may be one of the most picture-perfect places you will experience today.

One of the best things about exploring Milan on a self-guided tour is that you set the pace. There’s plenty of time for detours and discovering hidden gems. When you’re ready for your next stop, make your way to Galleria Vittorio Emanuele Ii, an impressive shopping mall in the city. If you’re up for more discoveries, don’t forget to reserve some time for Duomo Di Milano Museum.

Don’t forget to check out all the popular tours and experiences you can add to your travel plans in Italy. You can explore and select activities under each day of your itinerary.

After a day of adventure, treat yourself to an exquisite dinner at one of Milan's best restaurants.

Enjoy a delicious meal at Dessert Bar Milano, a top-rated dining destination in Milan. If you're in the mood to try something new, consider Radisson Blu Hotel Milan, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante Qui Si Mangia. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Milan this evening.

Round off your dining experience by visiting Kilburn Cocktail Bar Milano, a prime location for a drink. Alternatively, explore the distinctive characteristics of Bar Frida, a bar catering to every mood and preference. The Friends Pub Milano likewise offers a unique atmosphere, perfect for a memorable night out.

Raise your glass to another unforgettable day in Italy!

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Day 3

Day 3

  • Milan
  • More

Drive 223 km, 4 hours 55 min

  • Villa del Balbianello
  • Villa Carlotta
  • Sacro Monte della Beata Vergine del Soccorso - Ossuccio (co)
  • I Giardini di Villa Melzi
  • More

Wake up to day 3 of your road trip in Italy. On this day, you’ll embark on an exciting expedition discovering the enchanting sights and activities of Lenno, Rogaro, Ossuccio, and Loppia. With 1 night to stay in Milan, we encourage you to seize the day and discover the unexplored beauty of the city’s surroundings!

No visit to Milan is complete without Villa Del Balbianello. This increasingly popular villa is one of the top attractions in the village. Proceed to Villa Carlotta (lake Como), another must-visit attraction.

As you wander through the inviting streets of Milan, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Sacro Monte Della Beata Vergine Del Soccorso - Ossuccio (co). This frequently visited church is a traveler-favorite. Not far away, you’ll find I Giardini Di Villa Melzi, another key site on your sightseeing itinerary.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Milan.

Milan is a place where the culinary landscape is as diverse as its attractions. So before the day ends, treat your palate to a taste of local cuisine at one of the best restaurants in Milan.

Make sure to reserve a table at Bice Restaurant, an iconic dining spot in Milan. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Alto Ristorante, a popular restaurant in Milan. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Nero 9, a hidden gem nestled in Milan. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

After savoring a delicious meal, step into the vibrant nightlife at Bhangrabar, where the evening is just getting started. In the same way, Rufus Cocktail Bar offers a unique charm perfect for experiencing the local bar scene in Milan. Ostello Bello Grande is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

As the sun sets, rest up and recharge for the next leg of your road trip in Italy.

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Day 4

Day 4

  • Milan
  • Venice
  • More

Drive 279 km, 4 hours

  • Castelvecchio Museum
  • Castelvecchio Bridge
  • Verona Arena
  • piazza delle Erbe
  • piazza dei Signori
  • Ponte Pietra
  • More

On day 4 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, including Verona. When you’re not sightseeing, take time to relax at your chosen hotel in Venice, where you’ll be staying for 2 nights.

One of the most locally renowned attractions included on the itinerary is Castelvecchio Museum. This historic museum will help you start your sightseeing on top. Then, take a leisurely stroll to Castelvecchio Bridge and learn what makes this visually striking monument unique.

Throughout the day, make sure to take breaks to appreciate the surroundings. Next up, visit the wondrous Verona Arena. After exploring the stadium, head to Piazza Delle Erbe. This well-known public square is a highlight in Milan. As your day continues, stop by Piazza Dei Signori, known for its enchanting features. Lastly, don’t forget to check out the well-known Ponte Pietra. Enjoy exploring this incredible historical landmark at your own pace.

When you’re done exploring for the day, you’ll drive to your hotel in Venice. Check in and relax before you head out to tour the city.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Venice, it's often a good idea to reserve a table in advance.

Savor the flavors at Bauer Hotel, a top pick for dinner tonight. Alternatively, L'Osteria Le Guglie beckons with its unique menu offerings. Also, consider Corner Pub. With its consistent customer satisfaction, it’s an excellent option for dining in Venice tonight.

After your delicious meal, get a taste of the vibrant nightlife with a visit to Al Parlamento, known for its inviting atmosphere. The Caffe Rosso is another great option if you’re looking for a place to get the night started. Similarly, Adagio provides a great setting to enjoy the night away.

Savor another day of unforgettable experiences in Italy!

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Day 5

Day 5

  • Venice
  • More

Drive 15 km, 42 min

  • Bridge of Sighs
  • Doge's Palace
  • St Mark's Basilica
  • Piazza San Marco
  • Rialto Bridge
  • Murano
  • More

On day 5 of your road trip, you’ll start and end your day in Venice, where you have 1 night left to stay.

Let Bridge Of Sighs set the tone for the day. Spend some time admiring this UNESCO world heritage-listed monument before continuing your journey. Doge's Palace is your next stop. This interesting palace is one of the best-rated sights in Venice.

Consider grabbing some lunch or a light snack to keep your energy going. Beyond the above-mentioned attractions, today is also the perfect time to visit St Mark's Basilica. This majestic church is a sight to behold. To round off your sightseeing experience, visit Piazza San Marco and Rialto Bridge. If time allows, end your day with Murano, an enchanting handicraft store that offers a memorable conclusion to your exploration.

When you’re done exploring for the day, you’ll return to Venice and your accommodation.

Indulge in a memorable dining experience at one of Venice's most popular restaurants, and connect with friendly locals for a true cultural experience.

Treat yourself to a delightful dinner at Generator Venice, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Nevodi? It's another excellent option with a diverse menu. Consider reserving a table at Ristorante La Piazza as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Venice.

After enjoying a delightful dinner, why not delve into the vibrant local bar scene? You might want to spend the evening at Il Mercante, a well-loved spot among locals and tourists. Or, head to The Irish Pub Venezia. This bar boasts a welcoming environment that is perfect for winding down. You could also continue your night at Ai Stagneri, another top-rated place in the area.

Head back to your accommodation in Venice and get some rest to prepare for another magical day of your road trip in Italy.

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Day 6

Day 6

  • Venice
  • Florence
  • More

Drive 263 km, 3 hours 41 min

  • piazzale Michelangelo
  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • Cathedral of Santa Maria del Fiore
  • More

On day 6 of your road trip in Italy, your travel plans include 1 stop at the most scenic, wondrous, and interesting places in the region. Florence are on today's agenda. In the evening, you’ll end up in Florence, where you will stay for 2 nights.

Piazzale Michelangelo leaves a lasting impression. This observation deck is one of the most extraordinary places to visit in Venice. Next, head to Basilica Of Santa Croce In Florence, a popular church, known for its heritage-rich features.

In between the sights, don’t hesitate to take small detours to explore local stores and eateries. When you’re ready to continue your adventure, head to Uffizi Gallery. This historic art gallery is a highly recommended experience. Nearby, you'll also find Ponte Vecchio and Cathedral Of Santa Maria Del Fiore. Visit these for an interesting touch to your journey.

At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Enjoy a lovely meal at Ristorante Oliviero 1962, a top-rated place to have dinner tonight. Alternatively, if your taste buds call for something different, Di Poneta Novoli is another top choice with a popular menu. You could also check for a table at Caffe San Firenze. As an establishment that consistently gains high praises from customers, it’s an ideal choice in Florence tonight.

After savoring a delicious meal, step into the vibrant nightlife at Manifattura, where the evening is just getting started. In the same way, Se·sto On Arno Rooftop Bar offers a unique charm perfect for experiencing the local bar scene in Florence. Il Vinile is another top-recommended bar that is sure to get you into the mood for some dancing and celebrating.

Head back to your accommodation in Florence and get some rest to prepare for another magical day of your road trip in Italy.

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Day 7

Day 7

  • Florence
  • More

Drive 195 km, 3 hours 57 min

  • piazza del Campo
  • Siena Cathedral
  • Santuario di Santa Caterina
  • Fortezza Medicea
  • Porta San Giovanni
  • Villa Calcinaia - Conti Capponi
  • More

On day 7 of your road trip in Italy, you’ll start and end your day in Florence, but spend the day exploring what’s beyond the city. Since you still have 1 night to spend in Florence, there’s no need to rush. Experience Siena, San Gimignano, and Greti to the fullest today with this curated day itinerary.

Siena is brimming with adventures.

Visiting Piazza Del Campo is always a good idea. This spectacular public square is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the inviting wonders of Siena Cathedral, a must-see church in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Santuario Di Santa Caterina. This beloved church offers an enriching experience. For a change of pace, head to Fortezza Medicea (siena), where you can take in picture-perfect features. Conclude your self-guided sightseeing tour with a visit to Porta San Giovanni and Villa Calcinaia - Conti Capponi. These sights offer a fulfilling end to a perfect day.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Florence.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Florence, it's often a good idea to reserve a table in advance.

Don’t miss out on dining at Ditta Artigianale, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Trattoria Da Burde, another top spot with a mouthwatering menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.

Extend your evening after a delightful meal by visiting Bar 50 Rosso, which offers the perfect atmosphere for a night out. Moreover, Bitter Bar is another popular option for a drink or two. Likewise, Archea Brewery also provides a great ambiance for reminiscing about the day and raising a toast to your vacation.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 8

Day 8

  • Florence
  • La Spezia
  • More

Drive 183 km, 3 hours 16 min

  • Cittadella Nuova
  • Knights' Square
  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Pisa Cathedral
  • Santuario di Nostra Signora di Montenero
  • More

Dive into day 8 of your remarkable road trip in Italy. Today you'll explore 2 destinations, including Pisa and Riomaggiore. At the end of the day, you’ll unwind at one of the finest accommodations in La Spezia, where you'll spend 1 night.

Start your day at Cittadella Nuova. This romantic park is an up-and-coming place to see in Florence. Then, wander over to Knights' Square. If standout sites excite you, this public square will be right up your alley. Nearby, you’ll also find Leaning Tower Of Pisa. This historic monument is a favorite among visitors.

Florence offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Piazza Del Duomo, Pisa is a timeless spot in the city that will captivate you with its unique charm. When you’re done at the public square, don’t forget to check out the historic Pisa Cathedral. Take a moment to appreciate the fascinating details of this often recommended church. Wrap up your self-guided tour of Florence's top attractions with a visit to Nostra Signora Di Montenero.

After soaking up all the sights on today's itinerary, you'll be ready to head to your accommodation in La Spezia. La Spezia offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in La Spezia. Enjoy a relaxing evening as you savor delicious local cuisine.

Enjoy a delicious meal at The Colombaio Park, a top-rated dining destination in La Spezia.

Raise your glass to another unforgettable day in Italy!

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Day 9

Day 9

  • La Spezia
  • Milan
  • More

Drive 267 km, 4 hours 50 min

  • Castle of Riomaggiore
  • Riomaggiore
  • Manarola Overlook Viewpoint
  • Sentiero Azzurro
  • More

Your itinerary for day 9 of your road trip in Italy includes 3 stops and features some of the highlights of Riomaggiore, Manarola, and Corniglia. At the end of the day, enjoy the comforts of a top-rated hotel in Milan, where you'll spend 1 night.

Your adventure in La Spezia is only getting started when you visit Castle Of Riomaggiore, a locally appreciated local hot spot. Another notable attraction to explore is Riomaggiore. This frequently visited point of interest is known for its romantic appeal.

After soaking in the highlights of these sights, take some time to wander La Spezia's streets and immerse yourself in the local atmosphere. When you're ready to continue your sightseeing adventure, head to Manarola Overlook Viewpoint. This stunning observation deck offers a fascinating experience that many visitors find memorable. Sentiero Azzurro is also worth visiting.

When you’re done exploring for the day, you’ll drive to your hotel in Milan. Check in and relax before you head out to tour the city.

Indulge in a memorable dining experience at one of Milan's most popular restaurants, and connect with friendly locals for a true cultural experience.

Make sure to reserve a table at Ristorante la Brisa, an iconic dining spot in Milan. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Pasticceria San Carlo, a popular restaurant in Milan. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of UNAHOTELS Cusani Milano, a hidden gem nestled in Milan. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.

Following your dinner, dive into the local bar culture at Qc Termemilano. Enjoy this evening's relaxed ambiance with delightful drinks. Alternatively, go to Yguana Cafè, the perfect place for those looking to experience the best of the nightlife.

Relax and look forward to more memorable moments to come!

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Day 10

Day 10

  • Milan - Departure day
  • More
  • Pinacoteca di Brera
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Milan before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, begin at Pinacoteca Di Brera. This well-known art gallery is a hotspot among locals.

Take some time to indulge in shopping at Milan’s popular marketplace, Galleria Vittorio Emanuele II. Look for keepsakes or souvenirs to remind you of your trip. If you’re in the mood for luxury shopping, high-end stores await you.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Milan.

If you're in the mood to try something new, consider Palazzo Parigi Hotel & Grand Spa Milano, another top spot with a mouthwatering menu.

You’ll then say farewell to Milan. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.
Secure your spot
Confirm your package instantly and lock in the best rate with secure payment and guaranteed availability.
Get instant confirmation
Shortly after booking, you’ll receive your full itinerary, including schedules, locations, and everything you need for a stress-free trip.
Personalize your itinerary
Each package includes a professionally crafted itinerary you can tailor to your travel style. A dedicated travel expert will make sure every detail fits your needs perfectly.
Easily make changes
Need to update plans? No problem. Whether before your trip or mid-journey, we’re just seconds away to help with quick adjustments.
Enjoy seamless planning
With everything from accommodations to activities pre-arranged, our packages save you hours of research—so you can spend more time enjoying your trip, not planning it.
Explore with confidence
From scenic road trips to city-hopping adventures, we’re here 24/7 to support you across Europe—before, during, and after your trip.

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