10-Day Italy Self-Drive Road Trip With Itinerary from Milan traveling east to Venice, Florence, and La Spezia

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Explore the best of Italy on a 10-day road trip! Uncover hidden gems and experience the rich culture firsthand as you journey through Milan, Lenno, Ossuccio, Verona, Venice, Murano, Florence, Siena, San Gimignano, Pisa, Riomaggiore, La Spezia, Manarola, and Corniglia. This road trip itinerary in Italy seamlessly combines exploration with relaxation.

This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 4 nights in Milan, 2 nights in Venice, 2 nights in Florence, and 1 night in La Spezia. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!

With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.

Upon arriving in Milan, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.

An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Piazza San Marco and Rialto Bridge are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Duomo Di Milano Museum, learn more about the unique Verona Arena, and immerse yourself in the vibrant atmosphere of Ponte Vecchio.

As you hit the open road and drive through Milan, Lenno, Ossuccio, Verona, Venice, Murano, Florence, Siena, San Gimignano, Pisa, Riomaggiore, La Spezia, Manarola, and Corniglia, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.

Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.

This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.

The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!

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Driver’s age is 30 - 65
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Itinerary summary

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Days
Destination
Attractions
Overnight
Day
City & Overnight
Attractions
Corso Vittorio Emanuele II
Sempione ParkCastello SforzescoGalleria Vittorio Emanuele IIDuomo di MilanoBreraNavigli
Villa del BalbianelloVilla CarlottaSacro Monte della Beata Vergine del Soccorso - Ossuccio (co)I Giardini di Villa Melzi
Castelvecchio MuseumCastelvecchio BridgeVerona Arenapiazza delle Erbepiazza dei SignoriPonte Pietra
Bridge of SighsDoge's PalaceSt Mark's BasilicaPiazza San MarcoRialto BridgeMurano
piazzale MichelangeloBasilica of Santa Croce in FlorenceUffizi GalleryPonte VecchioCathedral of Santa Maria del Fiore

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Day 1

Day 1

  • Milan - Arrival day
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  • Corso Vittorio Emanuele II
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Your road trip adventure in Italy begins as soon as you reach Milan and pick up your car. You’ll stay in Milan for 3 nights and explore the best things to see and do, sample the local cuisine, and choose from a curated selection of the best hotels and places to stay in the city.

Milan is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Corso Vittorio Emanuele II, a must-see street, and taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.

Find your way to your hotel in Milan. We recommend choosing a hotel in a central location for easy exploring. Check-in typically starts between 2 and 4 PM at hotels in Italy. Settle in and make plans for the evening.

As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Milan, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Hotel Morfeo Milano, a highly-rated dining destination in Milan. If you're eager to try something different, consider Contraste, another top spot with a tantalizing menu. You might also want to secure a reservation at UNAHOTELS Galles Milano. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Milan this evening.

Let the evening flow smoothly from dinner to drinks at Nottingham Forest, a top-rated bar in the area. For other recommendations, Armani/bamboo Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Mag Cafe offers a memorable night with diverse drink options and excellent service.

Raise a toast to the start of your 10-day road trip in Italy!

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Day 2

Day 2

  • Milan
  • More

Drive 4 km, 38 min

  • Sempione Park
  • Castello Sforzesco
  • Galleria Vittorio Emanuele II
  • Duomo di Milano
  • Brera
  • Navigli
  • More

Day 2 offers a multitude of experiences. You will stay in Milan for 2 nights more, offering you enough time to explore at a relaxed pace.

A visit to Brera in Milan is a must on the agenda today. This neighborhood is full of hidden gems and character, perfect for a leisurely stroll. Plus, you’ll be close to some of the city’s most famous sights. Don’t forget to check out Navigli as well, a neighborhood that adds another layer to your exploration.

Get ready to discover some of the most iconic wonders in Milan, including a park, a castle, a shopping mall, a church and much more! Start your day at Parco Sempione. This awe-inspiring park is an impressive place to see in Milan. Then, wander over to Sforzesco Castle Art Library. If breathtaking sites excite you, this castle will be right up your alley. Nearby, you’ll also find Galleria Vittorio Emanuele Ii. This remarkable shopping mall is a favorite among visitors.

Milan offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Duomo Di Milano Museum is a timeless spot in the city that will captivate you with its unique charm.

Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Milan. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Enjoy a delicious meal at Dessert Bar Milano, a top-rated dining destination in Milan. If you're in the mood to try something new, consider Radisson Blu Hotel Milan, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante Qui Si Mangia. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Milan this evening.

To truly maximize your evening out, consider visiting Kilburn Cocktail Bar Milano after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Bar Frida, another bar with an inviting ambiance. Similarly, The Friends Pub Milano also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Raise your glass to another unforgettable day in Italy!

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Day 3

Day 3

  • Milan
  • More

Drive 223 km, 4 hours 55 min

  • Villa del Balbianello
  • Villa Carlotta
  • Sacro Monte della Beata Vergine del Soccorso - Ossuccio (co)
  • I Giardini di Villa Melzi
  • More

At the end of the day, you'll drive back to Milan, where you'll stay for 1 night more.

Prepare for a day full of family-friendly attractions, romantic experiences, and scenic views. When you’re ready, kick off your sightseeing adventure at Villa Del Balbianello. This underrated villa is a must-visit for anyone seeking a unique vacation experience. Another sight you shouldn’t miss is Villa Carlotta (lake Como), one of the village’s best highlights.

Next, check out Sacro Monte Della Beata Vergine Del Soccorso - Ossuccio (co), one of the most often recommended places to see in Milan. This church is a favorite among locals and travelers alike. Enjoy some downtime and refreshments before continuing to your next stop, I Giardini Di Villa Melzi. Wander around and soak in the remarkable atmosphere this botanical garden offers.

When you’re done exploring for the day, you’ll return to Milan and your accommodation.

As dinnertime approaches, it's time to head out for a bite to eat in Milan. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Dine in style at Bice Restaurant, a top recommendation for dinner tonight. Or, for a change of pace, Alto Ristorante boasts a menu that's sure to impress. Also, be sure to check out Nero 9. Known as a local hotspot, it’s a great choice for tonight in Milan.

Let the evening flow smoothly from dinner to drinks at Bhangrabar, a top-rated bar in the area. For other recommendations, Rufus Cocktail Bar provides a perfect setting for rounding out your night with style and great drinks. Likewise, Ostello Bello Grande offers a memorable night with diverse drink options and excellent service.

Celebrate another amazing day of your road trip adventure in Italy!

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Day 4

Day 4

  • Milan
  • Venice
  • More

Drive 279 km, 4 hours

  • Castelvecchio Museum
  • Castelvecchio Bridge
  • Verona Arena
  • piazza delle Erbe
  • piazza dei Signori
  • Ponte Pietra
  • More

On day 4 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Verona. In the evening, you’ll end up in Venice, where you will stay for 2 nights.

Set out on a day brimming with fun adventures, scenic views, and photo-friendly spots. Start at the notable Castelvecchio Museum, a gorgeous museum in Milan. Next, go to Castelvecchio Bridge.

After visiting Castelvecchio Museum and Castelvecchio Bridge, have a stroll along Milan's streets and take in the local charm. Continue your sightseeing by heading to Verona Arena. This visually striking stadium offers a unique experience. Piazza Delle Erbe is another noteworthy attraction worthwhile a visit. End your self-guided sightseeing tour on top with a visit to Piazza Dei Signori, one of the most visually striking places to visit in Milan. If you still have some time left for sightseeing, we also recommend stopping by Ponte Pietra.

At the end of the day, you will drive to Venice, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

As dinnertime approaches, it's time to head out for a bite to eat in Venice. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.

Enjoy a delicious meal at Bauer Hotel, a highly-rated dining destination in Venice. If you're eager to try something different, consider L'Osteria Le Guglie, another top spot with a tantalizing menu. You might also want to secure a reservation at Corner Pub. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Venice this evening.

To truly maximize your evening out, consider visiting Al Parlamento after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to The Caffe Rosso, another bar with an inviting ambiance. Similarly, Adagio also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.

Raise your glass to another unforgettable day in Italy!

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Day 5

Day 5

  • Venice
  • More

Drive 15 km, 42 min

  • Bridge of Sighs
  • Doge's Palace
  • St Mark's Basilica
  • Piazza San Marco
  • Rialto Bridge
  • Murano
  • More

Greet day 5 of your road trip in Italy with a smile and start your day with a hearty breakfast. You will return to Venice for your remaining 1 night in the city later today, but first, it’s time for some exploring! On the agenda for this day, you’ll find only the best things to see and do in Venice and Murano.

Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Venice allows for both. Start by heading to Bridge Of Sighs. This locally renowned monument provides an insightful glimpse into the city's identity. Next, discover Doge's Palace, a romantic palace, promising a delightful encounter.

Continue your sightseeing with a visit to St Mark's Basilica, a locally renowned church. When you’re done, don’t forget to make a stop at the iconic Piazza San Marco. Not far away from the public square, you will find the history-steeped Murano, perfect for a quick visit. Round off your day at Rialto Bridge, another gem in Venice with visually striking features to discover.

When you’re done exploring the area’s best attractions, you’ll drive back to your accommodation in Venice.

As you are wrapping up for the day, treat yourself to a satisfying dinner at a nice restaurant in Venice. Enjoy a relaxing evening as you savor delicious local cuisine and reflect on the day's adventures.

Don’t miss out on dining at Generator Venice, a top-rated dining destination in Venice. If you're in the mood to try something new, consider Nevodi, another top spot with a mouthwatering menu. You might also want to secure a reservation at Ristorante La Piazza. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Venice this evening.

After your meal, keep the night alive at a bar like Il Mercante, known for its lively atmosphere. The Irish Pub Venezia is another top recommendation that provides the perfect setting with well-crafted drinks and a welcoming ambiance. Similarly, Ai Stagneri offers an excellent atmosphere for those looking to amp up the evening.

Head back to your accommodation in Venice and get some rest in preparation for another magical day of your road trip in Italy!

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Day 6

Day 6

  • Venice
  • Florence
  • More

Drive 263 km, 3 hours 41 min

  • piazzale Michelangelo
  • Basilica of Santa Croce in Florence
  • Uffizi Gallery
  • Ponte Vecchio
  • Cathedral of Santa Maria del Fiore
  • More

Dive into day 6 of your remarkable road trip in Italy. Today you will explore Florence, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Florence. You’ll stay here for 2 nights.

Today’s itinerary in Venice covers several incredible sights, including an observation deck, a church, an art gallery, a historical landmark and much more! Start your adventure at Piazzale Michelangelo. This impressive observation deck is a place that is appreciated by travelers and locals alike. Next, immerse yourself in the instagrammable wonders of Basilica Of Santa Croce In Florence, a must-see church in the city.

Consider stopping for a small bite to eat or a drink at a local eatery to keep your energy going. When you’re ready, continue your discovery with a visit to Uffizi Gallery. This astonishing art gallery offers an enriching experience. For a change of pace, head to Ponte Vecchio, where you can take in history-steeped features. Conclude your self-guided sightseeing tour with a visit to Cathedral Of Santa Maria Del Fiore. These sights offer a fulfilling end to a perfect day.

After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Florence. Florence offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.

After a day of adventure, treat yourself to an exquisite dinner at one of Florence's best restaurants.

Enjoy a lovely dining experience at Ristorante Oliviero 1962, a popular restaurant in Florence. This acclaimed establishment has earned the admiration of countless food lovers in the city. Alternatively, experience a taste of Florence at Di Poneta Novoli, another great place to eat. With a menu designed to impress, it promises a journey of flavors that will leave you captivated. A third option to check out is the top-rated Caffe San Firenze. It’s yet another ideal choice to enhance your time in Florence tonight.

Continue your evening by exploring the vibrant nightlife scene at Manifattura, a prime destination for a thrilling night out. Also, don’t forget to check out Se·sto On Arno Rooftop Bar, a bar that offers unique local touches. Likewise, Il Vinile provides an excellent alternative for a fun evening.

Relax and recharge in preparation for another adventurous day in Italy!

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Day 7

Day 7

  • Florence
  • More

Drive 195 km, 3 hours 57 min

  • piazza del Campo
  • Siena Cathedral
  • Santuario di Santa Caterina
  • Fortezza Medicea
  • Porta San Giovanni
  • Villa Calcinaia - Conti Capponi
  • More

On day 7 of your road trip, you’ll start and end your day in Florence, but spend part of the day exploring places of interest outside the immediate city. On today's itinerary, you'll find attractions in Siena, San Gimignano, and Greti. You still have 1 night left in Florence.

Immerse yourself in Florence’s rich culture with today's sightseeing itinerary. Start your journey at Piazza Del Campo. This visually striking public square is sure to ignite your curiosity. Next, dive into the history-steeped features of Siena Cathedral, a must-visit church in the city.

In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Santuario Di Santa Caterina, an often recommended church. For a change of scene, check out Fortezza Medicea (siena), known for its historic features. We also recommend visiting Porta San Giovanni. This monument is a must for anyone looking to experience the city to the fullest. Lastly, end your day with a visit to Villa Calcinaia - Conti Capponi, yet another locally appreciated attraction in Florence.

When you’re done exploring for the day, you’ll return to Florence and your accommodation.

Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.

Savor the flavors at Ditta Artigianale, a top pick for dinner tonight. Alternatively, Trattoria Da Burde beckons with its unique menu offerings. Also, consider Casa Toscana. With its consistent customer satisfaction, it’s an excellent option for dining in Florence tonight.

Keep the excitement of the evening going by visiting a bar or two. Bar 50 Rosso is an excellent place to start. You could also check out Bitter Bar, offering a different kind of charm. A last recommendation for the day is Archea Brewery. This bar promises an enjoyable experience with tasty drinks and a vibrant setting.

As the day draws to a close, take a moment to unwind and prepare for the next exciting chapter of your road trip in in Italy.

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Day 8

Day 8

  • Florence
  • La Spezia
  • More

Drive 183 km, 3 hours 16 min

  • Cittadella Nuova
  • Knights' Square
  • Leaning Tower of Pisa
  • Piazza del Duomo, Pisa
  • Pisa Cathedral
  • Santuario di Nostra Signora di Montenero
  • More

Experience an unparalleled adventure on day 8 of your road trip in Italy. This exciting part of your journey invites you to discover the renowned landmarks in 2 vibrant destinations - Pisa and Riomaggiore. After a day filled with exploration and new experiences, you will retreat to the hotel of your choice in La Spezia. You will spend 1 night here for some well-deserved relaxation.

Today's adventure in Florence promises more breathtaking discoveries and enriching experiences! Begin at Cittadella Nuova. This visually striking park is a highlight of any visit in the city. Then, enjoy Knights' Square, another picture-perfect attraction that never fails to captivate visitors. Next, head over to Leaning Tower Of Pisa, one of the city’s most wondrous attractions, known for its culturally significant features.

If you’re looking for more, spend time soaking in the atmosphere of Piazza Del Duomo, Pisa. This picture-perfect public square is frequented by locals and tourists alike. To complete your memorable day, make sure to visit Pisa Cathedral, an up-and-coming church, and take a stroll around the area. If you want to extend your self-guided sightseeing tour, go check out Nostra Signora Di Montenero before you head back to your hotel.

When you’re done exploring for the day, you’ll drive to your hotel in La Spezia. Check in and spend some time relaxing before you head out to tour the city.

After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in La Spezia. Enjoy a satisfying meal that will recharge you for tonight's adventures.

Treat yourself to a delightful dinner at The Colombaio Park, highly recommended for tonight's dining.

Take some time to reflect on your day and savor another beautiful night in Italy.

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Day 9

Day 9

  • La Spezia
  • Milan
  • More

Drive 267 km, 4 hours 50 min

  • Castle of Riomaggiore
  • Riomaggiore
  • Manarola Overlook Viewpoint
  • Sentiero Azzurro
  • More

Embark on another extraordinary experience on day 9 of your road trip in Italy. Today, you will make 3 stops and experience some of the highlights of Riomaggiore, Manarola, and Corniglia. At the end of the day, you will enjoy the comforts of a top-rated hotel in Milan, which will be your home away from home for 1 night.

A blend of family-friendly attractions, romantic experiences, and scenic views await you in La Spezia on today’s itinerary. First up is the intriguing castle, Castle Of Riomaggiore. Afterward, continue to Riomaggiore, a sightseeing destination every traveler should visit.

As you explore La Spezia’s charming streets, take in the lively atmosphere and get to know the character of the village. Next, make your way to Manarola Overlook Viewpoint. This curiosity-inducing observation deck is an essential stop. Following that, head to Sentiero Azzurro, another must-visit site that will enhance your experience.

At the end of the day, you will drive to Milan, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.

Indulge in a memorable dining experience at one of Milan's most popular restaurants, and connect with friendly locals for an authentic adventure.

Treat yourself to a delicious dinner at Ristorante la Brisa, an excellent option for tonight's dining. Looking for something different? Pasticceria San Carlo offers a tantalizing alternative with its diverse menu. And don’t miss UNAHOTELS Cusani Milano. With its reputation for pleasing customers, it’s a fantastic choice for tonight in Milan.

Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Qc Termemilano stands out as an excellent choice for a post-dinner cocktail. Alternatively, Yguana Cafè offers an ideal atmosphere to enjoy the pleasures of the night.

Get a good night's sleep and look forward to another great day on the road in Italy!

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Day 10

Day 10

  • Milan - Departure day
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  • Pinacoteca di Brera
  • More

Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Milan before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.

If you're up for some more sightseeing, we recommend visiting Pinacoteca Di Brera, a visually striking art gallery before you head out.

Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones. Discover boutiques offering an array of stylish fashion choices. Take a break with a cup of coffee or tea while savoring the local vibe in a coffee shop.

Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Milan.

Savor the flavors at Vento di Sardegna, a top pick for dinner tonight. Alternatively, Palazzo Parigi Hotel & Grand Spa Milano beckons with its unique menu offerings.

You’ll then say farewell to Milan. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!

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