10-Day Italy Self-Drive Road Trip With Itinerary from Perugia to Rome, Siena, and Florence and surrounding area
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Description
Experience the freedom of the open road in Italy as you embark on an unforgettable 10-day road trip! This experience caters to every traveler, featuring destinations like Perugia, Rome, Siena, Pisa, and Florence.
This perfectly planned road trip itinerary in Italy takes you through some of the best places to see in the country. You will spend 3 nights in Perugia, 3 nights in Rome, 1 night in Siena, and 2 nights in Florence. Anticipate well-spent days sightseeing, eating delicious food, and experiencing the highlights of each destination!
With this travel package, you can choose from an extensive selection of accommodations along your road trip route in Italy. We have handpicked the best hotels and places to stay across the country, including options for each budget. Whether you are in the mood for luxurious 5-star hotels or budget-friendly bed and breakfasts, we have got you covered.
Upon arriving in Perugia, the rental vehicle of your choice will be ready for collection. From there, the road trip can begin! Experience the ultimate freedom and uncover Italy on your own terms.
An expertly curated travel plan makes sure you don’t miss out on any of the best things to see and do on your road trip in Italy. Trevi Fountain and Colosseum are just a couple of the bucket-list attractions that await your discovery. Marvel at the remarkable Pantheon, learn more about the unique Piazza Navona, and immerse yourself in the vibrant atmosphere of St. Peter's Basilica.
As you hit the open road and drive through Perugia, Rome, Siena, Pisa, and Florence, you will also enjoy plenty of opportunities to uncover hidden gems and experience the authentic charm of Italy. Whether you are exploring enchanting towns and villages, discovering scenic routes, or indulging in local cuisine, there is always something new and exciting to experience in Italy.
Throughout your road trip in Italy, take breaks from sightseeing to explore your favorite destinations' top shopping streets and markets. Discover unique souvenirs that will forever remind you of your self-drive adventure in Italy.
This package offers an all-in-one solution for your trip planning - choose flights, a rental car, accommodation, attractions, and tours that suit your needs and desires. You can customize each day of your road trip itinerary with flexible trip planning before and after booking.
The best services in Italy fill up quickly, so book your spot early. Select a date and start planning your road trip in Italy today!
Itinerary summary
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Day 1
- Perugia - Arrival day
- More
- Piazza IV Novembre
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Welcome to Perugia, the perfect starting point for your road trip in Italy! Pick up your rental car and let the adventure begin. You will spend 2 nights immersing yourself in Perugia's charm before embarking on the next leg of your journey.
Perugia is a beautiful city with plenty to discover. If you arrive before check-in time or prefer to get started on your sightseeing right away, we recommend checking out Piazza Iv Novembre, or just taking a stroll in the city center. Soak in the lovely atmosphere and sit down for a bit to eat or drink.
Make your way to your chosen hotel. Check-in typically starts between 2 and 4 PM in Perugia. Make yourself at home and enjoy some downtime before heading out again.
As dinnertime approaches, it's time to head out for a bite to eat. If you are looking to dine at a popular restaurant in Perugia, it's often a good idea to reserve a table in advance.
Have a fantastic dining experience at Ristorante Settimo Sigillo, a highly recommended choice for tonight's dinner. If you're looking to mix things up, Caffè Baglioni offers an enticing alternative with its varied menu. Additionally, Bar Pellas is worth considering. Renowned for satisfying diners, it’s an ideal option for tonight in Perugia.
To truly maximize your evening out, consider visiting Tommi Bar after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Valentina, another bar with an inviting ambiance. Similarly, Caffe Dal Perugino also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.
Raise a toast to the start of your 10-day road trip in Italy!
Day 2
- Perugia
- More
Drive 3 km, 49 min
- Frontone Gardens
- Convent of San Domenico
- Rocca Paolina
- Carducci Gardens
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Day 2 of your road trip across Italy promises a magnificent time exploring Perugia. You have 1 night left in Perugia. Take the opportunity to experience more of the best attractions and activities in the city.
Get ready to discover some of the most iconic wonders in Perugia, including a park, a church, and a historical landmark. Start your day at Frontone Gardens. This instagrammable park is a worthwhile place to see in Perugia. Then, wander over to Convent Of San Domenico. If culturally significant sites excite you, this church will be right up your alley. Nearby, you’ll also find Rocca Paolina. This photogenic historical landmark is a favorite among visitors.
Perugia offers plenty to explore, ensuring every moment of your visit is filled with excitement and discovery. If you're up for more, Carducci Gardens is a locally appreciated spot in the city that will captivate you with its unique charm.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
After a day of adventure, treat yourself to an exquisite dinner at one of Perugia's best restaurants.
Enjoy a delicious meal at La Taverna, a highly-rated dining destination in Perugia. If you're eager to try something different, consider Ristorante del Sole, another top spot with a tantalizing menu. You might also want to secure a reservation at Al Mangiar Bene. With a reputation for consistently satisfying customers, it’s an excellent choice to enhance your stay in Perugia this evening.
If you’re not ready to end the night just yet, Caffè Fortebraccio offers a perfect venue to relax and savor a drink. Similarly, Caffe Del Banco is well-suited for those looking to unwind in a social setting. Dempsey's Perugia is another excellent spot to enjoy a nightcap after a delightful meal.
Head back to your accommodation in Perugia and get some rest in preparation for another magical day of your road trip in Italy!
Day 3
- Perugia
- Rome
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Drive 184 km, 3 hours
- Vatican Museums
- Saint Peter's Square
- Sistine Chapel
- St Peter's Basilica
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Embark on another extraordinary experience on day 3 of your road trip in Italy. Today, you will make 1 stop and experience some of the highlights of Vatican City. At the end of the day, you will enjoy the comforts of a top-rated hotel in Rome, which will be your home away from home for 3 nights.
Whether you prefer a leisurely exploration or a more fast-paced adventure, this itinerary in Perugia allows for both. Start by heading to Vatican Museums. This wondrous art museum provides an insightful glimpse into the city's identity.
Continue your sightseeing with a visit to Sistine Chapel, a famous chapel. When you’re done, don’t forget to make a stop at the timeless St. Peter's Basilica.
When you’re done exploring for the day, you’ll drive to your hotel in Rome. Check in and spend some time relaxing before you head out to tour the city.
As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Begin your culinary exploration in Rome by securing a reservation at La Pergola. This renowned restaurant holds 3 Michelin star and offers an exceptional menu of mediterranean and contemporary cuisine. For another dining delight, visit Il Pagliaccio, celebrated for its delectable creative and innovative menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, making it a must-visit during your holiday. Looking for a different experience? Discover Enoteca La Torre, a top local spot known for its tantalizing mediterranean and creative menu. With a 2-star Michelin recognition, it guarantees an exceptional dining adventure.
Cap off your dinner by heading to La Botticella Of Poggi Giovanni, ideal for a leisurely evening with a drink in hand. Almalu Trastevere is another bar that offers an enjoyable setting. Similarly, Bar Viminale Di Pepi Maurilio is also a popular place to go on a night out, perfect for relaxing and socializing.
As the sun sets on another day of adventure, rest up and recharge for the next leg of your road trip in Italy.
Day 4
- Rome
- More
Drive 9 km, 52 min
- Villa Borghese
- Colosseum
- Roman Forum
- Altare della Patria
- Monti
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Day 4 of your road trip will take you to the best attractions Rome has to offer. Cherish the 2 nights you have left in Rome by discovering the best things there are to see and do in the city.
A top thing to do today is to explore Monti, a must-see neighborhood in Rome. It's the perfect starting point for touring the top attractions in the area.
Rome is home to plenty of attractions that offer fun adventures, romantic experiences, and natural wonders! Start at Villa Borghese, a widely recognized park that is worthwhile a visit in the city. Nearby, you’ll find Colosseum, enchanting visitors with its picture-perfect appeal. Continue your exploration at Roman Forum. This archeological site is one of the city’s most timeless spots.
Enjoy the freedom of exploring Rome at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Altare Della Patria.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As you explore more of Rome, you'll discover that its culinary landscape is as diverse as its attractions. Whether you're craving traditional dishes bursting with local flavors or innovative creations that push the boundaries of taste, you're sure to find a dining experience that satisfies your cravings.
Treat yourself to a delightful dinner at RomAntica, highly recommended for tonight's dining. Or, if you're feeling adventurous, why not try Coso Ristorante? It's another excellent option with a diverse menu. Consider reserving a table at DEROMA - Farine Romane as well. Known for its consistent customer satisfaction, it’s an ideal pick for tonight in Rome.
To truly maximize your evening out, consider visiting Sant' Eustachio Caffè after dinner. This bar is known for offering some of the best drinks and vibes in the city. Alternatively, head to Yellowsquare Rome, another bar with an inviting ambiance. Similarly, Caffè Portofino also offers a great atmosphere, ensuring a night filled with enjoyment and relaxation.
Get a good night's sleep and look forward to another great day on the road in Italy!
Day 5
- Rome
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Drive 5 km, 54 min
- Castel Sant'Angelo
- Piazza Navona
- Pantheon
- Campo de' Fiori
- Trastevere
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Day 5 offers a multitude of experiences. You will stay in Rome for 1 night more, offering you enough time to explore at a relaxed pace.
Trastevere is a fantastic place you can explore today in Rome. This neighborhood is a testament to the city’s character, and it's easy to spend hours just walking around and admiring the surroundings. Soak in the Rome-way-of-life and visit all the nearby sights.
Today’s route brings family-friendly attractions, romantic experiences, and scenic views. The first attraction of today is Castel Sant'angelo. This astonishing castle is a history-steeped place to see in Rome. Continue your discovery at Piazza Navona, a remarkable public square with stories to tell.
As you stroll around Rome, take in the distinct atmosphere and learn what makes this city so unique. Maximize your sightseeing with a visit to Pantheon. This wondrous monument offers a culturally significant encounter with Rome. Next, make your way to Campo De' Fiori to add another highlight to your day. Whether you decide to get entrance tickets for all attractions or you prefer admiring from a distance, amazing experiences await on this day in Rome.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
As dinnertime approaches, it's time to head out for a bite to eat in Rome. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Dine in style at Hotel de Russie, a top recommendation for dinner tonight. Or, for a change of pace, La Taverna Italiana boasts a menu that's sure to impress. Also, be sure to check out The Parrot Bar. Known as a local hotspot, it’s a great choice for tonight in Rome.
Explore the vibrant nightlife at The Apartment Bar Roma after your meal, a hub for lively evenings and memorable moments. Or, head to Hotel Hassler Roma for a great selection of flavorful drinks and a charming setting.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 6
- Rome
- Siena
- More
Drive 239 km, 3 hours 9 min
- Trevi Fountain
- Piazza di Spagna
- piazza del Popolo
- More
Dive into day 6 of your remarkable road trip in Italy. Today you will explore Rome, where you will have the opportunity to experience all the top things to see and do. At the end of the day, you’ll unwind at one of the finest accommodations in Siena. You’ll stay here for 1 night.
Today's adventure in Rome promises more breathtaking discoveries and enriching experiences! Begin at Trevi Fountain. This visually striking monument is a highlight of any visit in the city. Then, enjoy Piazza Di Spagna, another enchanting attraction that never fails to captivate visitors. Next, head over to Piazza Del Popolo, one of the city’s most famous attractions, known for its romantic features.
After soaking up all the sights of today's itinerary, you'll be ready to head in the direction of your accommodation in Siena. Siena offers plenty of top-rated hotels for every travel budget. Take some time to relax before you go out again.
As dinnertime approaches, it's time to head out for a bite to eat in Siena. If you are looking to dine at a popular restaurant in the city, it's often a good idea to reserve a table in advance.
Make sure to reserve a table at Enoteca I Terzi, an iconic dining spot in Siena. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Ristorante Tar-Tufo, a popular restaurant in Siena. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Antica Trattoria Papei, a hidden gem nestled in Siena. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
After your delicious meal, get a taste of the vibrant nightlife with a visit to Meet Life Cafè, known for its inviting atmosphere. Maudit Pub is another great option if you’re looking for a place to get the night started. Similarly, Bar Impero Siena provides a great setting to enjoy the night away.
Say good night to Siena and look forward to another great day of your road trip in Italy!
Day 7
- Siena
- Florence
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Drive 216 km, 3 hours 30 min
- piazza del Campo
- Siena Cathedral
- Leaning Tower of Pisa
- Piazza del Duomo, Pisa
- Campo santo
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On day 7 of your road trip in Italy, you will get a true taste of the freedom a self-drive vacation in Europe entails. Today’s travel plans include stops at the most scenic, wondrous, and interesting places in Siena and Pisa. In the evening, you’ll end up in Florence, where you will stay for 2 nights.
Discover a day packed with family-friendly attractions, romantic experiences, and breathtaking views in Siena. Begin your sightseeing with Piazza Del Campo. This widely recognized public square is one of the top attractions in the city. Proceed to Siena Cathedral, another must-visit attraction.
As you wander through the inviting streets of Siena, soak in the lively ambiance and take the opportunity to snap some photos. Next, head to Leaning Tower Of Pisa. This timeless monument is a traveler-favorite. Not far away, you’ll find Piazza Del Duomo, Pisa, another key site on your sightseeing itinerary. Campo Santo is yet another highly recommended place to visit nearby, offering plenty to discover for curious travelers.
At the end of the day, you will drive to Florence, where you'll have a room waiting for you at the perfect place to stay. Check in and enjoy some downtime.
Indulge in a memorable dining experience at one of Florence's most popular restaurants, and connect with friendly locals for an authentic adventure.
Dive into a culinary adventure like no other in Florence by booking a table at Enoteca Pinchiorri. This popular restaurant holds 3 Michelin star and offers an exceptional menu of italian contemporary cuisine. For another culinary dining option, venture to Santa Elisabetta, celebrated for its delectable creative and mediterranean menu. This acclaimed 2-star Michelin-recipient consistently leaves guests satisfied, ensuring an essential addition to your holiday itinerary. Seeking an alternative? Discover Gucci Osteria da Massimo Bottura, a top local restaurant known for its tantalizing italian contemporary and international menu. With a 1-star Michelin recognition, it promises an exceptional dining experience not to be missed.
Cap off your culinary experience with a visit to some of the most celebrated bars in the area. For instance, Manifattura stands out as an excellent choice for a post-dinner cocktail. Alternatively, Se·sto On Arno Rooftop Bar offers an ideal atmosphere to enjoy the pleasures of the night. Il Vinile is also a great option that provides a perfect setting for a relaxing evening.
Relax and reminisce about your day in Italy and look forward to more memorable moments to come!
Day 8
- Florence
- More
Drive 11 km, 1 hour 19 min
- Central Market
- Galleria dell'Accademia
- Cathedral of Santa Maria del Fiore
- The Boboli Gardens
- Oltrarno
- More
On day 8 of your road trip, you will have an entire day to explore Florence. You’ll stay in Florence for 1 night and discover all the best things to see and do in the area.
Oltrarno is one of the highlights of today. Take your time exploring this iconic neighborhood in Florence, which offers a perfect blend of history and culture. Plus, it's close to many must-see landmarks in the city.
Immerse yourself in Florence’s rich culture with today's sightseeing itinerary. Start your journey at Central Market. This eye-catching food market is sure to ignite your curiosity. Next, dive into the photogenic features of Galleria Dell'accademia, a must-visit art gallery in the city.
In between sights, stop by local stores, picturesque photo spots, and small eateries. When you’re ready for your next attraction, proceed to Cathedral Of Santa Maria Del Fiore, an astonishing church. For a change of scene, check out The Boboli Gardens, known for its romantic features.
Don’t forget to check out all the popular tours and activities you can add to your road trip itinerary. Italy is a beautiful travel destination that offers plenty of unique tours that will enhance your vacation experience. Explore and select your activities below.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Florence. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Enjoy a delicious meal at Ditta Artigianale, a top-rated dining destination in Florence. If you're in the mood to try something new, consider Trattoria Da Burde, another top spot with a mouthwatering menu. You might also want to secure a reservation at Casa Toscana. With a reputation for consistently satisfying customers, it’s a perfect choice to enhance your stay in Florence this evening.
Round off your dining experience by visiting Bar 50 Rosso, a prime location for a drink. Alternatively, explore the distinctive characteristics of Bitter Bar, a bar catering to every mood and preference. Archea Brewery likewise offers a unique atmosphere, perfect for a memorable night out.
Celebrate another amazing day of your road trip adventure in Italy!
Day 9
- Florence
- Perugia
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Drive 154 km, 2 hours 32 min
- piazza della Signoria
- Ponte Vecchio
- Uffizi Gallery
- Basilica of Santa Croce in Florence
- piazzale Michelangelo
- More
On day 9 of your exciting self-drive vacation in Italy, you’ll soak in the magnificence of 1 destination, Florence. When you’re not sightseeing, take time to relax at your selected hotel in Perugia, where you’ll be staying for 1 night.
Florence is home to plenty of attractions that offer family-friendly attractions, romantic experiences, and breathtaking views! Start at Piazza Della Signoria, an extraordinary public square that is worthwhile a visit in the city. Nearby, you’ll find Ponte Vecchio, enchanting visitors with its history-steeped appeal. Continue your exploration at Uffizi Gallery. This art gallery is one of the city’s most astonishing spots.
Enjoy the freedom of exploring Florence at your own pace and find hidden gems along the way. If you want to see more picture-perfect spots, make sure to visit Basilica Of Santa Croce In Florence. After exploring the church, head to the famous Piazzale Michelangelo.
When you’re done exploring for the day, you’ll drive to your hotel in Perugia. Check in and spend some time relaxing before you head out to tour the city.
After a long day of exploring, sit down for a delicious dinner at a top-rated restaurant in Perugia. Enjoy a satisfying meal that will recharge you for tonight's adventures.
Make sure to reserve a table at Perugia Plaza Hotel, an iconic dining spot in Perugia. This culinary treasure and its outstanding menu have enchanted food enthusiasts from around the world. Immerse yourself in the culinary delights of Elfo Pub Perugia, a popular restaurant in Perugia. With a menu designed to delight, it ensures a dining experience that transcends the ordinary. Experience the culinary magic of Sangallo Palace Hotel, a hidden gem nestled in Perugia. Known for its exquisite cuisine and inviting atmosphere, it's a dining experience you won't soon forget.
Keep the evening going at Il Birrino, a great choice for enjoying the after-dinner hours with a drink. You could also go to Quei Bravi Ragazzi, which offers a similarly pleasant setting and great drinks. Another option is Lo Chalet - Lounge Bar, which provides an inviting environment for unwinding after a busy day out.
Get a good night's sleep and look forward to another great day on the road in Italy!
Day 10
- Perugia - Departure day
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- Etruscan Arch
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Day 10 of your road trip in Italy is your departure day. This is your chance to catch a last glimpse of Perugia before saying goodbye to this wonderful destination. If you've still got time left, we recommend doing some last-minute shopping or sightseeing.
If you're up for some more sightseeing, begin at Etruscan Arch. This beloved historical landmark is a popular place to see in the city.
Explore local shops for souvenirs to remember your trip or find unique gifts for loved ones.
Before you conclude your road trip in Italy, drop by another restaurant for a last chance at a memorable dining experience in Perugia.
Treat yourself to a delicious dinner at Alphaville, an excellent option for tonight's dining. Looking for something different? Osteria a Priori offers a tantalizing alternative with its diverse menu. And don’t miss La Bottega di Perugia.
You’ll then say farewell to Perugia. Drive to the airport, return your car, and take the opportunity to get some last-minute souvenirs before you board your flight home. We wish you a pleasant journey and hope you leave with many wonderful memories of your road trip in Italy!
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